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Isolated Ectopia Lentis

Ectopia Lentis Et Pupillae


Presentation

  • Patients with ectopia lentis commonly present with a marked loss in visual acuity in addition to a number of possibly accompanying ocular complications including cataract, myopia, and retinal detachment.[ncbi.nlm.nih.gov]
  • Our study presented detailed clinical manifestations, including some novel ophthalmic findings, such as pupillary abnormality, different types of glaucoma, and progressive hyperopia.[ncbi.nlm.nih.gov]
  • The information presented is not intended to replace medical advice or treatment from your own doctor or healthcare provider.[wellnessadvocate.com]
  • A 27-year-old man presented with complaint of low visual acuity. No evidence of the syndrome was found at presentation. The results of supplementary tests were normal.[ncbi.nlm.nih.gov]
  • Type your tag names separated by a space and hit enter Abstract A rare case of congenital bilateral ectopia lentis et pupillae (ELEP) is reported in a 32 year old female presenting with complaints of diminution of vision in both eyes.[unboundmedicine.com]
Nightmare
  • Agarwal is the author of several books published by SLACK Incorporated, publisher of Ocular Surgery News, including Phaco Nightmares: Conquering Cataract Catastrophes, Bimanual Phaco: Mastering the Phakonit/MICS Technique, Dry Eye: A Practical Guide to[healio.com]
Pupillary Abnormality
  • Our study presented detailed clinical manifestations, including some novel ophthalmic findings, such as pupillary abnormality, different types of glaucoma, and progressive hyperopia.[ncbi.nlm.nih.gov]
  • There were no areas of iris atrophy, pupillary abnormalities, or iris transillumination in any of the 18 patients examined or their relatives.[cags.org.ae]
  • According to him, absence or hypoplasia of the dilator muscle of the pupil manifesting as corectopia also suggested neuroectodermal origin of ectopia lentis associated with pupillary abnormalities.[ijo.in]
  • Professor, Ulucanlar Eye Training and Research Hospital, Ankara/TURKEY Ectopia lentis et pupillae is a rare congenital hereditary disorder usually characterized with a combination of ectopia lentis and pupillary abnormalities, but without systemic manifestations[glaucomacataractjournal.com]
Arthralgia
  • Clinical: Patients may have arthralgias, seizures, episodes of tetany, muscular weakness, or paresthesia; also may be asymptomatic. Al-Ghamdi SM, Cameron EC, Sutton RA. Magnesium deficiency: pathophysiologic and Clinical review.[uchebana5.ru]
Impulsivity
  • The lens is the transparent structure inside the eye that focuses light rays onto the retina (the nerve layer that lines the back of the eye, senses light, and creates impulses that go through the optic nerve to the brain).[marfan.org]
Screaming
  • Dan let out a loud scream and immediately grabbed his eye. He was relieved to find out that he wasn't bleeding, however, his vision was very blurry and the eye was getting very swollen.[study.com]
Cognitive Deficit
  • When caused by a mutation in the ADAMTSL4 gene, IEL is inherited in an autosomal recessive manner. 0001387 30%-79% of people have these symptoms Cognitive impairment Abnormality of cognition Cognitive abnormality Cognitive defects Cognitive deficits Intellectual[rarediseases.info.nih.gov]
Excitement
  • It was considered that the only definitive treatment would be to remove the exciting hypermature lens from the vitreous. Figure 1 Preoperative slit-lamp photograph of left eye.[nature.com]

Workup

  • An overview Signs and Symptoms Etiology of ectopia lentis Workup and evaluation Treatment Low Vision Management Conculsion Reference Workup and evaluation Sharma IP 34. Detailed history History of ocular trauma.[slideshare.net]
  • Workup  Cardiac evaluation for Marfan syndrome  Serum and urine levels of homocysteine or methionine for homocystinuria  Axial length measurement 32.[slideshare.net]
  • Twenty-four people presented for complete ophthalmological workups. In addition, complete detailed clinical examinations including echocardiography could be performed in six people ( Table 1 ). All mutation carriers showed ocular involvement only.[molvis.org]

Treatment

  • The uveitis responded to treatment with g betamethasone q.d.s., but persisting raised IOP required the substitution of g latanoprost o.n. for dorzolamide.[nature.com]
  • Nienaber's and Fattori's new book aptly is addressing both the diagnos tic procedure as well as the treatment of aortic disease.[books.google.de]
  • The information presented is not intended to replace medical advice or treatment from your own doctor or healthcare provider.[wellnessadvocate.com]
  • Ectopia Lentis et Pupillae Syndrome: Treatment Treatment depends on how far the lens has been dislocated out of place.[study.com]
  • Treatment Treatment Options: Lens removal may be indicated when vision cannot otherwise be corrected. References References Chandra A, Aragon-Martin JA, Sharif S, Parulekar M, Child A, Arno G.[disorders.eyes.arizona.edu]

Prognosis

  • Prognosis - Ectopia lentis isolated Not supplied. Treatment - Ectopia lentis isolated Not supplied. Resources - Ectopia lentis isolated Not supplied.[checkorphan.org]
  • Diagnosis of the ectopia lentis et pupillae is fundamental not only to evaluate the risk, prognosis and treatment, but also to assist in differentiating other syndromes with systemic impairment.[ncbi.nlm.nih.gov]
  • Treatment and prognosis Complications An anterior dislocation/subluxation carries greater complications than a posterior one. Such complications include: acute glaucoma corneal injury iridal injury Promoted articles (advertising)[radiopaedia.org]
  • PROGNOSIS • Good visual prognosis with early intervention and routine follow-up. • Even in patients requiring lensectomy most achieve vision of 20/40 or better ( 1 ). – If not complicated by untreated amblyopia.[entokey.com]
  • Prognosis An individual’s prognosis depends on any underlying ocular or systemic disease, the degree of subluxation, and the management strategy pursued.[eyewiki.aao.org]

Etiology

  • Lyons, both globally recognized leaders, provide authoritative coverage of all the pediatric ophthalmic conditions you’re likely to encounter in practice, including the latest clinical advances in etiology, diagnosis, and medical and surgical management[books.google.de]
  • An overview Signs and Symptoms Etiology of ectopia lentis Workup and evaluation Treatment Low Vision Management Conculsion Reference Etiology of ectopia lentis Sharma IP 16.[slideshare.net]
  • Pathology Etiology trauma systemic and syndromic disorders Marfan syndrome typically upwards and out most common spontaneous cause 2 homocystinuria - typically downwards Weil-Marchesani syndrome Ehlers-Danlos syndrome hereditary (or isolated) ectopia[radiopaedia.org]
  • As ectopia lentis may be the first sign of a more serious systemic disease, it is important to determine the etiology for appropriate patient management.[eyewiki.aao.org]
  • Etiologic Classification Etiology Congenital Metabolic Disorder Traumatic Consecutive or Spontaneous 5. Congenital Ectopia Lentis  Usually bilateral and symmetrical Simple Ectopia Lentis Ectopia Lentis et Pupillae 6.[slideshare.net]

Epidemiology

  • EPIDEMIOLOGY Incidence • Marfan disease 4–6/100,000 births ( 1 ) and approximately 60–75% have ectopia lentis. • Homocystinuria 1/200,000 births ( 1 ) and approximately 80–85% have ectopia lentis. Prevalence Unknown.[entokey.com]
  • Epidemiology Frequency  A rare condition.  Incidence in the general population is unknown. Mortality/Morbidity  Can cause marked visual disturbance, depending the degree of lens displacement and the underlying etiology Sex  More common in males.[slideshare.net]
  • Although no clear epidemiological data is available, it has been suggested that congenital EL may have a prevalence of six per 100 000. 22 It is probable that the second most common cause of EL is a condition termed isolated ectopia lentis (IEL). 22,[nature.com]
Sex distribution
Age distribution

Pathophysiology

  • Pathophysiology  Underlying pathophysiology - Disruption or dysfunction of the zonular fibers of the lens, regardless of cause (trauma or heritable condition)  The degree of zonular impairment determines the degree of lens Sharma IP 10.[slideshare.net]
  • PATHOPHYSIOLOGY Weakening or stretching of the zonular attachments lens ( 1 ).[entokey.com]
  • A recent study of over thousand probands with Marfan syndrome and FBN1 mutations demonstrated a striking correlation between ectopia lentis and mutations affecting cysteine residues, leading to the speculation that the pathophysiology of ectopia lentis[molvis.org]
  • Magnesium deficiency: pathophysiologic and Clinical review. Am J Kidney Dis 1994; 24:737-752. Bourcier T, et al. Sclerochoroidal calcification associated with Gitelman syndrome. Am J Ophthalmol 1999; 128: 767-768.[uchebana5.ru]

Prevention

  • Prevention - Ectopia lentis isolated Not supplied. Diagnosis - Ectopia lentis isolated signs and symptoms of Ectopia lentis, isolated may vary on an individual basis for each patient.[checkorphan.org]
  • And are not intended to diagnose, treat, cure or prevent disease. The information presented is not intended to replace medical advice or treatment from your own doctor or healthcare provider.[wellnessadvocate.com]
  • Prevent and plan for complications in advance by examining over 1,600 illustrations, photos and graphics (1,250 in color) capturing essential diagnostics techniques, imaging methods and surgical approaches.[books.google.ro]
  • The bag-in-the-lens intra-ocular lens technique was used to accommodate this small ill-suspended capsule and to prevent secondary cataract formation in this young child.[escrs.org]
  • Foods rich in Vitamin A - Weight Loss For All Five Tips For Eye Health to prevent cataracts and other eye problems after 3 Surprising Health Facts about your Eyes Shopping for eye health is similar to shopping for general health unlabeled eye diagram[pinterest.de]

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