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Isolated Iridoschisis

Presentation

ICE most often presents as a unilateral, progressive finding in the third to fourth decade of life, in contrast to iridoschisis which is often bilateral and presents in the fifth to seventh decade of life.[25][26] While iridoschisis is characterized by [eyewiki.aao.org]

Entire Body System

  • Developmental Disorder

    A spectrum of developmental disorders. Surv Ophthalmol. 1985;29:387–409 ↑ 27.0 27.1 Romano A, Treister G, Barishak R, Stein R. Iridoschisis and angle-closure glaucoma. [eyewiki.aao.org]

Psychiatrical

  • Suggestibility

    They suggested that these conditions induced an intraocular pressure (IOP) spike, forcing aqueous humor into the iris, and subsequently splitting the anterior and posterior portions of the iris stroma. [eyewiki.aao.org]

Treatment

[…] glaucoma Reznicek L, Seidensticker F, Mann T, Hübert I, Buerger A, Haritoglou C, Neubauer AS, Kampik A, Hirneiss C, Kernt M Clinical Ophthalmology 2013, 7:1883-1888 Published Date: 19 September 2013 Original Research Real-world variability in ranibizumab treatment [dovepress.com]

[…] with miotics can cause a mechanical shearing action that provokes tearing of the iris stroma.[9] However, miotics were used quite commonly in the treatment of glaucoma for many years, and there has been no associated increase in the prevalence of iridoschisis [eyewiki.aao.org]

Etiology

[…] anterior stromal, and posterior stromal layers.[3] Epidemiology/Pathophysiology There have been over 100 cases of iridoschisis reported in the literature.[4] Though a number of ideas exist, there is not yet one defining theory of the pathogenesis or etiology [eyewiki.aao.org]

Epidemiology

This allowed for the first histological study of the condition, which revealed deep clefts between largely atrophic anterior stromal, and posterior stromal layers.[3] Epidemiology/Pathophysiology There have been over 100 cases of iridoschisis reported [eyewiki.aao.org]

Pathophysiology

This allowed for the first histological study of the condition, which revealed deep clefts between largely atrophic anterior stromal, and posterior stromal layers.[3] Epidemiology/Pathophysiology There have been over 100 cases of iridoschisis reported [eyewiki.aao.org]

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