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2.1
Jatropha Curcas Poisoning
Purge Nut Poisoning

Presentation

The phorbol esters present in the seed cake act as a biological pesticide particularly against soil nematodes, slugs and snails that are harmful to plants. [jatropower.ch]

Zimbabwe Present Introduced Not invasive Chivandi et al., 2005 North America Mexico Present Native Not invasive Natural USDA-ARS, 2008 USA Present Present based on regional distribution. [cabi.org]

Patient number 4, ingested 10 seeds, presented with nausea, vomiting, abdominal pain and diarrhea. His initial laboratory results had elevated AST (49 U/L) and elevated ALT (80 U/L). [apjmt.mums.ac.ir]

Presented here is an unfortunate incident of mass poisoning, where some people (mostly children) consumed jatropha fruits & seeds mistaking them for edible sunflower seeds. Victims were hospitalized, promptly managed and recuperated successfully. [ingentaconnect.com]

We present a case report about J. curcas poisoning. [sajch.org.za]

Entire Body System

  • Gastric Lavage

    Childrean are especially vulnerable because of the pleasant-tasting seeds. [1] [2] [9] Management Gastric lavage is often done unless vomiting has been extensive. Treated with bismuth subcarbonate and magnesium trisilicate to protect the stomach. [globinmed.com]

Gastrointestinal

  • Vomiting

    As per limited literatures available on the subject, the toxic products of Jatropha are known to cause nausea, vomiting, diarrhoea and atropine like symptoms. [worldwidejournals.com]

    […] and antiemetic drug 2 5 Nausea, vomiting Elevated AST (AST=39) 3 Intravenous hydration and antiemetic drug 3 10 Nausea, vomiting and diarrhea Elevated AST/ALT (AST=70, ALT=94) 3 Intravenous hydration and antiemetic drug 4 10 Nausea, vomiting, abdominal [apjmt.mums.ac.ir]

    Vomiting and diarrhoea can set in within fifteen minutes of consumption. Acute abdominal pain is experienced about half an hour after the ingestion of the seeds. [jrfmt.com]

    Symptoms of poisoning occur about 30 minutes after ingestion and include burning in the throat, nausea, vomiting, dehydration, cardiovascular collapse, and diarrhea. Vomit and feces may contain blood. [wildernessarena.com]

    Within two hours all of them were rushed to hospital suffering abdominal pain‚ nausea‚ vomiting‚ diarrhoea and a burning sensation in the throat. [medicalbrief.co.za]

  • Nausea

    As per limited literatures available on the subject, the toxic products of Jatropha are known to cause nausea, vomiting, diarrhoea and atropine like symptoms. [worldwidejournals.com]

    […] and antiemetic drug 2 5 Nausea, vomiting Elevated AST (AST=39) 3 Intravenous hydration and antiemetic drug 3 10 Nausea, vomiting and diarrhea Elevated AST/ALT (AST=70, ALT=94) 3 Intravenous hydration and antiemetic drug 4 10 Nausea, vomiting, abdominal [apjmt.mums.ac.ir]

    Within two hours all of them were rushed to hospital suffering abdominal pain‚ nausea‚ vomiting‚ diarrhoea and a burning sensation in the throat. [medicalbrief.co.za]

    Four children suffered severe symptoms of abdominal pain, nausea and vomiting after ingesting the seeds of J. curcas. These cases support the listing of J. curcas as a noxious weed. [sajch.org.za]

    Higher Education and Training (DHET) SciELO SA Science Citation Index (Web of Science (WoS) Core Collection) Abstract HTML Metrics Related Content Abstract During the first 3 months of 1983 8 children were admitted to Ga-Rankuwa Hospital with marked nausea [journals.co.za]

  • Diarrhea

    The clinical manifestations of curcin poisoning consist of nausea, vomiting, abdominal pain, diarrhea and hepatitis. [apjmt.mums.ac.ir]

    However, we found a group of 18 agricultural labourers affected by the poisoning of its seeds, who presented with complaints of vomiting, colicky abdominal pain, giddiness and diarrhea with in few minutes and reported to the casualty in a couple of hours [i-scholar.in]

    Side Effects, Risk Factors of, and Cautions for Jatropha Prolonged and excessive intake of Jatropha may cause : Poisoning Vomiting Abdominal Pain Nausea Diarrhea Weakness Children are highly susceptible to Jatropha Poisoning. [herbpathy.com]

    Symptoms of poisoning occur about 30 minutes after ingestion and include burning in the throat, nausea, vomiting, dehydration, cardiovascular collapse, and diarrhea. Vomit and feces may contain blood. [wildernessarena.com]

    Homeopathically used for cold sweats, colic, collapse, cramps, cyanosis, diarrhea, leg cramps. [hort.purdue.edu]

Musculoskeletal

  • Leg Cramp

    Difficulty in breathing, sorethroat, bloating, dizziness, vomiting, diarrhoea, drowsiness, dysuria, and leg cramps. The abdominal symptoms of intense pain, nausea, vomiting, and diarrhoea may appear within an hour after ingestion. [globinmed.com]

    Homeopathically used for cold sweats, colic, collapse, cramps, cyanosis, diarrhea, leg cramps. [hort.purdue.edu]

Neurologic

  • Dizziness

    Difficulty in breathing, sorethroat, bloating, dizziness, vomiting, diarrhoea, drowsiness, dysuria, and leg cramps. The abdominal symptoms of intense pain, nausea, vomiting, and diarrhoea may appear within an hour after ingestion. [globinmed.com]

  • Giddiness

    However, we found a group of 18 agricultural labourers affected by the poisoning of its seeds, who presented with complaints of vomiting, colicky abdominal pain, giddiness and diarrhea with in few minutes and reported to the casualty in a couple of hours [i-scholar.in]

Urogenital

  • Dysuria

    Difficulty in breathing, sorethroat, bloating, dizziness, vomiting, diarrhoea, drowsiness, dysuria, and leg cramps. The abdominal symptoms of intense pain, nausea, vomiting, and diarrhoea may appear within an hour after ingestion. [globinmed.com]

Treatment

In alternative, the oil of Barbados nut seeds can be applied for wood-coating treatment as a preservative measure to prevent termite attack. [myhousepests.com]

Sources at Manondwane Primary School in Bulawayo’s Nketa 7 said 16 pupils ingested the toxic fruits at the school playground at around 10AM and the rest of the class was taken for treatment as a precaution. [chronicle.co.zw]

The seeds are also used in the treatment of syphilis[303 ]. The oil from the seeds, known as 'curcas'’ is a powerful purgative and emetic[46, 272 ]. [pfaf.org]

Treatment is essentially symptomatic and supportive. Physic nut is usually avoided by horses, except during periods of drought and/or little other food is available to eat. [horsedvm.com]

Poisonous Plants: First Aid and Medical Treatment of Injuries. University of Hawaii. 2000 pg 88. 8. C.P. Khare. Indian Medicinal Plants: An Illustrated Dictionary Springer-Verlag, Berlin. 2007 pg. 345. 9. [globinmed.com]

Prevention

Get the skills you need now with new information on global humanitarian relief and expedition medicine, plus expanded coverage of injury prevention and environmental preservation. [books.google.com]

In alternative, the oil of Barbados nut seeds can be applied for wood-coating treatment as a preservative measure to prevent termite attack. [myhousepests.com]

These restrictions may prevent the use of one or more of the methods referred to, depending on individual circumstances. [keyserver.lucidcentral.org]

He said the school should cut down the tree to prevent a repeat of the horror. “It’s scary to know that such dangerous trees exist in schools. Our kids’ are no longer safe and I hear that many schools planted them. They should just chop them down.” [chronicle.co.zw]

[…] component of seed storage oil, is mainly synthesized by phospholipid:diacylglycerol acyltransferase in Jatropha, and continuous high expression of homologs of oleosin over seed development contributes to accumulation of high level of oil in kernels by preventing [ncbi.nlm.nih.gov]

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