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JC Virus Infection


  • "JC virus DNA is present in many human brain samples from patients without progressive multifocal leukoencephalopathy". J. Virol. 66 (10): 5726–4. PMC 241447. PMID 1326640.[en.wikipedia.org]


  • […] and later isolated in culture and named using the two initials of a patient, John Cunningham, with progressive multifocal leukoencephalopathy (PML). [5] The virus causes PML and other diseases only in cases of immunodeficiency, as in AIDS or during treatment[en.wikipedia.org]


  • Further research is needed to determine the exact etiological role of T-antigen, but there seems to be a connection to the early initiation of the active virus from its archetypal dormant state.[en.wikipedia.org]


  • "Molecular biology, epidemiology, and pathogenesis of progressive multifocal leukoencephalopathy, the JC virus-induced demyelinating disease of the human brain". Clin. Microbiol. Rev. 25 (3): 471–506. doi : 10.1128/CMR.05031-11. PMC 3416490.[en.wikipedia.org]
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