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Joint Contracture


  • METHODS: In the present study, we investigated its molecular mechanism, focusing on the role of a transcription factor, hypoxia inducible factor-1 (HIF-1), which regulates the expression of connective tissue growth factor (CTGF) and vascular endothelial[ncbi.nlm.nih.gov]
  • We present a new patient of this syndrome, with frequent fractures, congenital joint contractures, kyphoscoliosis, bilateral clubfoot, and pectus carinatum. The clinical and genetic features of all previously reported cases are also reviewed.[ncbi.nlm.nih.gov]
  • The clinical features of the present case are similar to those of the Emery-Dreifuss syndrome; however, this case may be inherited through an autosomal recessive trait.[ncbi.nlm.nih.gov]
  • The present study investigates whether VEGF is also involved in the development of shoulder contracture in diabetics with rotator cuff disease.[ncbi.nlm.nih.gov]
  • Learning issues, if present, can be mild.[ped-rheum.biomedcentral.com]
  • Haug Browse recently published Learning/CME Learning/CME View all learning/CME CME Partial Oral versus Intravenous Antibiotic Treatment of Endocarditis Case 4-2019: An 18-Year-Old Man with Abdominal Pain and Hematochezia Bridging the Gap Challenge Yourself[nejm.org]
Flexion Contracture
  • The knee flexion contractures were corrected from 38.9 degrees preoperatively to a mean of 6.5 degrees postoperatively and to 17.3 degrees at follow-up (34 months).[ncbi.nlm.nih.gov]
  • Abstract The most frequent cause of flexion contracture is immobilization, which may occur with or without trauma. Posttraumatic flexion contracture mainly develops from direct injury, intraarticular fluid and the physiological muscle balance.[ncbi.nlm.nih.gov]
  • Abstract Various splints are available for the correction of proximal interphalangeal (PIP) joint flexion contracture in patients with hand injuries. This article discusses the mechanics of several splints.[ajot.aota.org]
  • Congenital knee flexion contracture. 4th ed. Philadelphia: Saunders Elsevier; 2008. p. 926–9. Google Scholar 19. Van Bosse HJP, Feldman DS, Anavian J, Sala DA. Treatment of knee flexion contractures in patients with arthrogryposis.[link.springer.com]
  • Some examples: a knee flexion contracture lacks full extension; an elbow extension contracture lacks full flexion; and an ankle plantar flexion contracture lacks dorsiflexion.[clinicalgate.com]
Unable to Walk
  • In addition, she experienced humeropelvic muscular weakness and atrophy, so that she was unable to walk by age 27. At 34 years of age, she required a permanent pacemaker to treat complete atrioventricular block with ventricular bradycardia.[ncbi.nlm.nih.gov]
Speech Disorders
  • It can cause breathing problems, speech disorders, and make feeding difficult for infants. It can also occasionally cause developmental delays.[gillettechildrens.org]
  • Over time all involuntary movements are slowed, and dystonia and loss of motor control dominate. Prevention of contractures is very important in maintaining ability to walk and to do daily living activities.[endoflifecare.tripod.com]


  • Abstract The prevention and treatment of scar contracture is critical after significant burn injuries to avoid functional impairment. However, descriptions of specific contracture treatment interventions and outcomes are limited.[ncbi.nlm.nih.gov]
  • A 22-year-old male with a PIP joint contraction following replantation failed conventional treatment for release.[ncbi.nlm.nih.gov]
  • INTERVENTIONS: After remobilization, rats were assigned to 3 treatment groups: stretching only (S), stretching with infrared therapy (S IR), and stretching with ultrasonic therapy (S US). Six treatment sessions were given in 2 weeks.[ncbi.nlm.nih.gov]
  • BACKGROUND: Limited range of motion (ROM) as a result of joint contracture in treatment associated with joint immobilization or motor paralysis is a critical issue.[ncbi.nlm.nih.gov]
  • Abstract The purpose of this study was to investigate the efficacy of an external fixator (Ilizarov apparatus) for the treatment of severe joint contractures in patients with arthrogryposis multiplex congenita.[ncbi.nlm.nih.gov]


  • Prognosis of Posterior Joint Capsule Contracture Due to advanced medical technology and medical care facilities the prognosis for posterior joint capsule contracture is much better than earlier years.[epainassist.com]
  • Changes in bone shape are also common and may infl uence prognosis and management. In children, joint contractures pose a particular problem.[link.springer.com]
  • Prognosis Prognosis of contractures will depend upon the cause of the contracture. In general, the earlier the treatment for the contracture begins, the better the prognosis.[medical-dictionary.thefreedictionary.com]
  • Prognosis The course of the disease is variable in terms of how fast and how far it will progress. It does not inevitably progress to contracture. Most patients do not require surgery.[patient.info]


  • BACKGROUNDS: There have been many reports describing that the capsular fibrosis of the shoulder joint is the main cause of frozen shoulder, whereas others reported the significance of subacromial impingement as an etiological factor.[ncbi.nlm.nih.gov]
  • Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology.[icd10coded.com]
  • Etiology The aetiology remains unknown. There are currently no human genes associated with this disease. Diagnostic methods The features of the hand are especially important for the diagnosis.[orpha.net]
  • A joint contracture can have a congenital or an acquired etiology. Regardless of the cause, all joint contractures can interfere with a child’s ability to function at full capacity.[link.springer.com]
  • Epidemiology/Etiology Flexion deformities can arise by different causes.[physio-pedia.com]


  • Summary Epidemiology Less than 20 cases have been reported in the literature. Clinical description The fingers are thin with absent knuckles and reduced creases over the joints, and patients show an inability to make a full fist.[orpha.net]
  • Epidemiological studies indicate a wide range of prevalence of joint contractures in older individuals between 20% and 80% [ 2 – 4 ].[bmcgeriatr.biomedcentral.com]
  • The epidemiology of major joint contractures: a systematic review of the literature. Clinical Orthopaedics & Related Research. 2007:456:22-299. Huckstep RL. Management of neglected joint contractures.[health.cvs.com]
  • Epidemiology/Etiology Flexion deformities can arise by different causes.[physio-pedia.com]
  • See Epidemiology and Presentation. Although the cause of Dupuytren disease is unknown, a family history is often present.[emedicine.medscape.com]
Sex distribution
Age distribution


  • Since there is no clear understanding of the pathophysiology of posterior joint capsule contracture, both in vitro and animal studies, are required to examine the tissue's cellular and mechanical response to repetitive tensile loads which lead to pathophysiology[epainassist.com]
  • As with any progressive metabolic disease, early initiation of therapy that addresses the underlying pathophysiology improves outcome, and can prevent or at least delay the development of irreversible disease manifestations.[ped-rheum.biomedcentral.com]
  • Pathogenesis/Etiology Although the underlying etiology for the development of Dupuytren disease is uncertain, the basic pathophysiology involves fibroblast proliferation, and collagen deposition leading to contractures of the palmar fascia.[emedicine.medscape.com]


  • These results imply that inflammation and nociception are involved in myogenic contracture formation independently of joint immobilization, and that CBX is effective in preventing joint contracture following immobilization in rats.[ncbi.nlm.nih.gov]
  • Providing frequent changes in position and range of motion exercises is important to prevent contrac- tures. The participation of a physiotherapist in his care is critically important to prevent serious pro- gressive deformity.[endoflifecare.tripod.com]
  • This will prevent the occurrence of DVT and movement in the ankle joint will alleviate stiffness.[clinicaltrials.gov]
  • Prevention: Prevention of contractures depends on the cause.[knowyourdisease.com]
  • Joint contracture is preventable. Once a joint wound has started to heal, the patient can enroll in massage therapy, learning exercises from a professional. Stretches can prevent permanent damage from contracture.[scarfade.com]

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