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Jugular Foramen Syndrome


Presentation

  • We present the case of a 58-year-old diabetic renal transplant patient who developed a left jugular foramen syndrome, secondary to an ipsilateral staphylococcal malignant (necrotizing) otitis externa.[ncbi.nlm.nih.gov]
  • We report an elderly man who presents with dysphagia, dysarthria, hoarseness, and a 12-pound weight loss. Examination demonstrated paralysis of the right vagus and hypoglossal nerve.[ncbi.nlm.nih.gov]
  • Argoff, MD and Gary McCleane, MD who present a thorough update on the latest in pain management. Presents a new contemporary internal design that helps you navigate the text easier.[books.google.com]
  • Extramedullary plasmacytoma of the head and neck was discussed and its relation to cranial nerve dysfunction was reviewed, with presentation of an unusual case of plasmacytoma resulting in a variant of the jugular foramen syndrome.[ncbi.nlm.nih.gov]
  • Presents full-color images throughout to match the images that you see in practice. Extensive use of "combination" imaging presents a complete picture of how to more precisely locate and target the radiotherapy field.[books.google.com]
Hoarseness
  • A 46-year-old male patient was evaluated for hoarseness. It was learnt from his anamnesis that he had been operated for otitis media nearly 20 years ago. Uvula deviated towards right. Loss of gag reflex was remarkable on the left.[ncbi.nlm.nih.gov]
  • We report an elderly man who presents with dysphagia, dysarthria, hoarseness, and a 12-pound weight loss. Examination demonstrated paralysis of the right vagus and hypoglossal nerve.[ncbi.nlm.nih.gov]
  • As such, in an affected patient, you may find: dysphonia/hoarseness soft palate dropping deviation of the uvula towards the normal side dysphagia loss of sensory function from the posterior 1/3 of the tongue decrease in the parotid gland secretion loss[en.wikipedia.org]
  • […] carotid nerve tumor (primary form the nasopharynx or secondary from the uper cervical lymph nodes) symptoms : - pain in or behind ear due to irritation of the auricular branches of the 9 and 10 - headache due to irritation of the meningeal branch of 10 -hoarseness[cobocards.com]
Cough
  • Features depend on involved nerves: Symptions: Choking, dysphagia, speech changes, auditor canal pain, headache Features by nerve: IX: loss of gag reflex, sensation of the palate, auditor canal pain, glossopharyngeal neuralgia X: hoarse voice, weak cough[learningneurology.com]
  • He also noticed that he is coughing while eating food. There was no history of fever, trauma or ear discharge.[cancerjournal.net]
  • The larger, posterolateral, “pars vascularis” compartment contains CN X, CN XI, Arnold's nerve (or the auricular branch of CN X involved in the Arnold's reflex, where external auditory meatus stimulation causes cough), jugular bulb, and posterior meningeal[operativeneurosurgery.com]
  • Also, the cough reflex is partially mediated via general visceral afferent parasympathetic fibers. [4] The cough reflex is initiated by cough receptors.[ruralneuropractice.com]
  • Over the next two days the patient continued to spike high temperatures and developed a productive cough. Chest X-ray revealed an abscess and infiltrate in the right lung.[ispub.com]
Gagging
  • Loss of gag reflex was remarkable on the left. Paresis was found on the left vocal cord. There was weakness in rotation of the head to the right.[ncbi.nlm.nih.gov]
  • […] such, in an affected patient, you may find: dysphonia/hoarseness soft palate dropping deviation of the uvula towards the normal side dysphagia loss of sensory function from the posterior 1/3 of the tongue decrease in the parotid gland secretion loss of gag[en.wikipedia.org]
  • Cerebellopontine Angle Syndrome Acoustic Tumours CN IX and CN VIII and CN V can be affected Symptoms: IX: Tinnitus Gag reflex decreased VIII: Vertigo Deafness V Facial Sensory defecit Jugular Foramen Syndrome (Vernet Syndrome) Glomus Jugular Tumours Base[en.wikibooks.org]
  • ’s syndrome Hypoglossal canal syndrome, Foramen magnum syndrome, Carotid canal syndrome Clinical features: Features depend on involved nerves: Symptions: Choking, dysphagia, speech changes, auditor canal pain, headache Features by nerve: IX: loss of gag[learningneurology.com]
Nausea
  • A small number of patients present primarily with a phaeochromocytoma-like picture - eg, perspiration, pallor, nausea, hypertension and tachycardia.[patient.info]
  • For 2 months, he complained of dizziness, nauseas, vomiting and frontal headache irradiated to the whole cranium. In this period, he presented with three episodes of the syncope.[arquivosdeorl.org.br]
  • Other related symptoms include headache, perspiration, pallor, and nausea [ 13 , 14 ]. The treatment of glomus jugulare tumors presents the surgeon with a significant management problem.[wjso.biomedcentral.com]
  • Other related symptoms include headache, perspiration, pallor, and nausea. [ 3 ] Otoscopic examination reveals a characteristic, pulsatile, reddish-blue tumor behind the tympanic membrane that is often the beginning of more extensive findings (ie, the[emedicine.medscape.com]
Vomiting
  • Nystagmus, diplopia, vertigo, vomiting Vestibular nucleus. 4. Horner’s syndrome Descending sympathetic tract 5. Dysphagia, hoarseness, gag reflex negative IX, X nerve. 6. Loss of taste Nucleus & tractus solitarius 7.[gradestack.com]
  • For 2 months, he complained of dizziness, nauseas, vomiting and frontal headache irradiated to the whole cranium. In this period, he presented with three episodes of the syncope.[arquivosdeorl.org.br]
Choking
  • […] lacerocondylar area syndrome intercondylar space syndrome Retropharyngeal space syndrome Villaret’s syndrome Hypoglossal canal syndrome, Foramen magnum syndrome, Carotid canal syndrome Clinical features: Features depend on involved nerves: Symptions: Choking[learningneurology.com]
Corneal Opacity
  • Neurologically, his higher mental functions were normal; fundus could not be checked because of bilateral corneal opacities.[cancerjournal.net]
Hypertrichosis
  • Cyclosporin-induced hypertrichosis (excess hair growth) in his external auditory canal contributed greatly to the initial difficulty in managing his otitis externa.[ncbi.nlm.nih.gov]
Cranial Nerve Involvement
  • Cranial nerve examination showed left sided facial droop with drooling of saliva, left sided sensorineural deafness, impaired gag reflex on left side and difficulty in swallowing (left seventh, eighth, ninth and tenth cranial nerve involvement).[cancerjournal.net]
  • Cranial nerve involvement produces hoarseness and dysphagia.[wjso.biomedcentral.com]
  • Lower cranial nerve involvement as the initial manifestation of Lyme borreliosis. Neurologia 1999;14:36-7. 86. Hirabayashi K, Morikawa N, Mori H, Miyake T, Suda K, Kondo T, et al.[ruralneuropractice.com]
Nasal Speech
  • Vagus nerve lesion (X) Etiology Clinical features Loss of the gag reflex (efferent limb) Flaccid paralysis of the soft palate nasal speech and deviation of the uvula away from the lesion Epiglottic paralysis aspiration Dysphagia Features of vocal cord[amboss.com]

Workup

  • The purpose of this section is to define this syndrome and elucidate the epidemiology, pathogenesis, clinical manifestations, diagnostic workup, and general treatment options for the syndrome.[doctorabel.us]
  • After diagnosis has been made additional investigations are required as part of the preoperative workup.[jnnp.bmj.com]
Borrelia Burgdorferi
  • In rare cases Clostridium botulinum infection may involve cranial nerves. [84] Particularly hemorrhaghe within the vagal nerve has been reported. [84] Borreliosis Borreliosis and Lyme disease are due to an infection with the spirochete Borrelia burgdorferi[ruralneuropractice.com]

Treatment

  • Early surgery is important to completely reverse the lost nerve functions in treatment.[ncbi.nlm.nih.gov]
  • Despite further intensive treatment including antimicrobials, a subtotal petrosectomy and hyperbaric oxygen therapy he eventually succumbed to his disease.[ncbi.nlm.nih.gov]
  • (November 2017) Treatment [ edit ] This section is empty. You can help by adding to it . (November 2017) References [ edit ] Erol FS, Kaplan M, Kavakli A, Ozveren MF.Jugular foramen syndrome caused by choleastatoma.[en.wikipedia.org]
  • The tumor was small and located entirely within the jugular foramen; the patient sought treatment for a jugular foramen syndrome.[ncbi.nlm.nih.gov]
  • Progressing from fundamental principles through specific treatment strategies for the cancers of each organ system, it also addresses the effects of radiation on normal structures and the avoidance of complications.[books.google.com]

Prognosis

  • […] multiple swelling all over the body and the patient had painful enlargement that he perceived as an ongoing process of the von Recklinghausen's disease and made a delay in seeking the medical advice resulting in a well advanced disease and with poor prognosis[cancerjournal.net]
  • Retropharyngeal lymph nodes [ edit ] It is not clear whether these are staged as N0 or N1, with differences among institutions Prognosis for RLN N0 appears comparable to N1 RLNs atrophy with age, and are usually obliterated by adulthood.[en.wikibooks.org]
  • Fraktur tipe longitudinal memiliki prognosis paling buruk, terutama bila mengenai sistem vertebrobasilar.[skepra27osis.wordpress.com]
  • Prognosis Glomus jugulare tumours tend to grow slowly with only a small proportion metastasising. The associated cranial nerve palsies tend to be more cosmetic than debilitating.[patient.info]
  • Prognosis bervariasi tergantung dari keparahan stroke, lokasi dan volume perdarahan Semakin rendah nilai GCS maka prognosis semakin buruk dan tingkat mortalitasnya tinggi Semakin besar volume perdarahan maka prognosis semakin buruk, dan adanya darah[sarafambarawa.wordpress.com]

Etiology

  • While trauma, vascular disease, and infection may be etiologic, most cases result from malignancies, usually metastatic. We have described a case of metastatic adenocarcinoma of the prostate resulting in the Collet-Sicard variant of this syndrome.[ncbi.nlm.nih.gov]
  • TREATMENT Treatment must be directed toward the primary etiology.[doctorabel.us]
  • Tanaka M, Hirai S, Okamoto K, Morimatsu M, Yamaguchi H (1987) Benign and idiopathic jugular foramen syndrome-an etiological consideration. Clin Neurol (Tokyo) 27:329–333 Google Scholar Copyright information Authors and Affiliations H. Sawada 1 F.[link.springer.com]
  • Etiology Clinical features Extorsion of the eye : inability to depress and adduct the eyeball simultaneously (the pupil shoots upward during attempted adduction of the eyeball) Diplopia ( double vision ) Mild esotropia Trigeminal nerve lesion (V) Etiology[amboss.com]
  • Etiology A variety of neoplasms, vascular insults, infections, and trauma have been reported to cause JFS 2) .[neurocirugia.com]

Epidemiology

  • The purpose of this section is to define this syndrome and elucidate the epidemiology, pathogenesis, clinical manifestations, diagnostic workup, and general treatment options for the syndrome.[doctorabel.us]
  • Epidemiology [ 1 ] The annual incidence is about 1 in 1.3 million people per year. However, it is the most common tumour of the middle ear and the second most common tumour of the temporal bone.[patient.info]
  • From Wikibooks, open books for an open world Jump to navigation Jump to search Nasopharyngeal Cancer Overview Epidemiology [ edit ] Markedly different geographical prevalence Rare in the US: 0.2-0.5 cases per 100,000 people Common in China, Hong Kong[en.wikibooks.org]
  • Epidemiologi Epidemiologiske data er noe sprikende, trolig som en følge av at forfatterne har brukt ulike diagnostiske kriterier. Tilstanden debuterer i 1 – 8 års alder, med en topp rundt 3 – 5 år. Gutter er hyppigere affisert enn jenter ( 3 ).[tidsskriftet.no]
  • Epidemiology Glomus tumors occur with an estimated annual incidence of 1 case per 1.3 million people. [ 16 ] Although rare, glomus tumors are the most common tumor of the middle ear and are second to vestibular schwannoma as the most common tumor of the[emedicine.medscape.com]
Sex distribution
Age distribution

Pathophysiology

  • The potential role of hypocortisolism in the pathophysiology of stress-related bodily disorders. Psychoneuroendocrinology, 25(1), 1-35. ‎ Pagina 52 - In: Wall PD, Melzack R (eds), Textbook of pain. Churchill Livingstone, Edinburgh... ‎[books.google.it]
  • PATHOGENESIS Mass effect on neural contents of the jugular foramen from various neoplastic, vascular, infectious, and inflammatory processes is the main pathophysiologic mechanism of this syndrome.[doctorabel.us]
  • Pathophysiology (Ref. Hari. 18 th ed., Pg- 3362) In acute Bell's palsy there is inflammation of the facial nerve with mononuclear cells, consistent with an infectious or immune cause.[gradestack.com]
  • Pathophysiology The glomera jugulare, or glomus bodies, are small collections of paraganglionic tissue.[emedicine.medscape.com]
  • Pathophysiology, diagnostics and therapy of chronic cough: Neuronal reflexes and antitussiva. Pneumologie 2013;67:327-34. 5. Samandari F, Resßig D. Functional anatomy of cranial nerves and the vegetative nervous system.[ruralneuropractice.com]

Prevention

  • Prevention of bone loss with alendronate in postmenopausal women under 60 years of age. ‎ Pagina 74 - Heim, C".., Ehlert, U., & Hellhammer, DH (2000). The potential role of hypocortisolism in the pathophysiology of stress-related bodily disorders.[books.google.it]
  • Watertight closure with grafts, packing of the cavity with fat, and use of vascularized muscle flap are used to prevent CSF leak and its complications.[thamburaj.com]
  • Intraoperative mapping and monitoring of the motor rootlets at the cerebellomedullary cistern using endotracheal tube electrodes is a safe and effective procedure to prevent its injury. see jugular foramen stenosis .[operativeneurosurgery.com]
  • The indications for surgery include associated deep space neck infections, carotid sheath involvement (to prevent extension into the carotid artery), intra-luminal abscess and failed medical treatment.[ispub.com]
  • Management comprises appropriate antibiotic treatment supplemented by anticoagulation to prevent septic emboli, steroids to reduce oedema, and surgery to drain the primary infective source.[jnnp.bmj.com]

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