We present the case of a 16-yearold Yemeni boy with juvenile colloid milium, who presented with an unusual variant of juvenile colloid milium with waxy transparent papules on the helices which resembled a cutaneous horn. [avensonline.org]

In this case report we present a case of colloid milium in a 55 years old male with verrucous violaceous colloid milium on the dorsum of both hands, face, and ears. [article.sapub.org]

In this report, three cases, all presenting as multiple plaques and nodules over the nose and the face are depicted. [idoj.in]

Solar elastosis is often present immediately adjacent to colloid deposits. Nodular type: Deposits are similar to the adult type, but exist in most of the dermis. [dermatologyadvisor.com]

In this case report, we present a 52-year-old man who presented with a nodule on his upper lip that mistakenly was diagnosed and treated as keloid. Read More Unusual Manifestations of Familial Juvenile Colloid Milium in Two Siblings. [pubfacts.com]

• Hodgkin Lymphoma

  Non-Hodgkins lymphoma and auricular hypoplasia: associated with juvenile colloid milium or ligneous conjunctivitis? J Eur Acad Dermatol Venereol 2005;19:348-51. Hidayat AA, Riddle PJ. Ligneous conjunctivitis. A clinicopathologic study of 17 cases. [medigraphic.com]

  Non-Hodgkin’s lymphoma and auricular hypoplasia: associated with juvenile colloid milium or ligneous conjunctivitis? J Eur Acad Dermatol Venereol. 2005;19:348–351. [PubMed] [Google Scholar] 12. Denguezli M, Ghariani N, Kourda M, et al. [ncbi.nlm.nih.gov]

• Periodontitis

  There are usually no systemic implications, with the exception of a rare ligneous conjunctivitis or periodontitis in the juvenile type. [moh-it.pure.elsevier.com]

  Unusual involvements have also been reported, with nodular colloid milium located on the conjunctiva and anterior orbit (15), upper eyelid (16), the oral cavity (17) or in association with ligneous conjunctivitis or periodontitis (5). [ncbi.nlm.nih.gov]

• Facial Angiofibroma

  A clinical suspicion of facial angiofibromas associated with tuberous sclerosis complex has been raised and, because of the lack of additional clinical features required to sustain this diagnosis, a cutaneous biopsy has been considered. [ncbi.nlm.nih.gov]

The sun exposure is linked to the pathogenesis and treatment basically is photoprotection. REFERENCES Muscardin M, Bellocci M, Balus L. Papuloverrucous colloid milium: an occupational variant. Br J Dermatol 2000;143:884- 87. [medigraphic.com]

Treatment Options No satisfactory therapies are currently available. Treatment options are summarized in the Table 1. Table 1. [dermatologyadvisor.com]

She was continued with the same treatment and reviewed after 3 months. At this time, the woody membrane over conjunctiva had recurred because definitive treatment with plasminogen could not be started. [journals.lww.com]

Hence, we continued with the same treatment, but again the woody membrane recurred. [cyberleninka.org]

Treatment of Poikiloderma of Civatte with an intense pulsed light source. Dermatol Surg 2000; 26: 823-7. [jpma.org.pk]

Prognosis Colloid milium lesions remain static and do not resolve. Lesions reach their peak within 3 years, after which very few new papules occur. Patient Education Genetic counseling is advisable for the rare juvenile form of colloid milium. [emedicine.medscape.com]

Discussion Colloid milium is a degenerative change of uncertain etiology, There are three main forms of colloid milium: adult, juvenile and nodular colloid degeneration type [1, 2]. [article.sapub.org]

We suggest the long-term sun exposure as an etiologic factor; thus sun protection would be the most preventive and available treatment. [idoj.in]

Several etiologies have been postulated including chronic exposure to UV light, contact with petroleum products, application of bleaching creams containing hydroquinone, and genetic predisposition [1]. [escholarship.org]

Etiology The classic adult and nodular forms of colloid milium are believed to be due to excessive sun exposure, which appears to cause degeneration of elastin. [emedicine.medscape.com]

Etiology Possible risk factors have been identified, but the origin and mechanism of pathogenesis remain unclear. For the adult and nodular forms, unprotected and prolonged UV exposure is likely responsible for the skin degeneration. [dermatologyadvisor.com]

Prolonged use of hydroquinones has resulted in the development of the pigmented form of colloid milium, sometimes in association with ochronosis. [13] Epidemiology Frequency Colloid milium is rare, but more than 100 case reports are present in the world [emedicine.medscape.com]

Similar to adult colloid milium (ACM), sun exposure appears to be an important factor in inducing such lesions in susceptible pediatric patients, but the two diseases show different pathophysiology and clinicopathological features. [ncbi.nlm.nih.gov]

We suggest the long-term sun exposure as an etiologic factor; thus sun protection would be the most preventive and available treatment. [idoj.in]

Protection from the sun and petroleum derivatives is advised, but whether these precautions are actually preventive is still unclear. No follow-up is needed and it is not yet determined if maintenance therapy is required once successfully treated. [dermatologyadvisor.com]

Exposure to sunlight is thought to be a pivotal factor and could be responsible for the structural damage caused to the elastin, thereby preventing elastin synthesis in fibroblasts. [elsevier.es]