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Juvenile Temporal Arteritis
Non-Giant Cell Granulomatous Temporal Arteritis with Eosinophilia

Presentation

Only 11.4% of patients presented general symptoms and 6.8% a biological inflammatory syndrome; 34.1% had peripheral blood eosinophilia; 83.7% presented a single episode and complete excision without further treatment was documented for 72.7%. [pubmed.ncbi.nlm.nih.gov]

Peripheral blood eosinophilia could be present [2]. [ncbi.nlm.nih.gov]

Workup

Systemic workup revealed a mildly elevated erythrocyte sedimentation rate, mild changes in white and red blood cells, and a remote history of sensorineural hearing loss. [ajnr.org]

Treatment

The first chapter stresses the etiology and pathophysiology of childhood stroke as the basis for evaluations and treatment. [books.google.com]

We describe the first known case of bilateral JTA in a 21-year-old man and differential diagnoses are discussed to distinguish JTA from the classic giant cell (temporal) arteritis of the elderly, which requires corticosteroid drug treatment. [ncbi.nlm.nih.gov]

A new treatment for Giant Cell Arteritis The Food and Drug Administration accepted Roche’s supplemental biologics license application (sBLA) for Actemra (tocilizumab) under priority review with the aim of seeking the approval of this product in the treatment [pulseheadlines.com]

[…] effective ‘emergency’ treatment option to prevent damage such as vision loss. [pharmanews.eu]

[…] an effective ‘emergency’ treatment option to prevent damage such as vision loss. [roche.com]

Prognosis

The prognosis of the diseases is considered to be good. [ncbi.nlm.nih.gov]

The prognosis of the diseases is considered to be good. © 1996 S. [karger.com]

Etiology

The first chapter stresses the etiology and pathophysiology of childhood stroke as the basis for evaluations and treatment. [books.google.com]

INTRODUCTION: Juvenile temporal arteritis (JTA) is a recently-described and little-known inflammatory disease and its etiology is undetermined. Less than forty cases have been published. [ncbi.nlm.nih.gov]

Abstract Introduction: Juvenile temporal arteritis (JTA) is a recently-described and little-known inflammatory disease and its etiology is undetermined. Less than forty cases have been published. [pubmed.ncbi.nlm.nih.gov]

Epidemiology

Epidemiology of giant cell arteritis and polymyalgia rheumatica. Arthritis Rheum. 2009; 61 (10): 1454-61[ DOI ][ PubMed ] 4. Kobayashi S, Yano T, Matsumoto Y, Numano F, Nakajima N, Yasuda K, et al. [ircmj.com]

Temporal arteritis, a 25-year epidemiologic, clinical, and pathologic study. Ann Intern Med 1978;88:162–167.PMID: 626444 Salvarani C, Cantini F, Boiardi L, et al. Polymyalgia rheumatica and giant-cell arteritis. [rheumaknowledgy.com]

[…] healthily—helping to maintain a strong immune system and build strong muscles and bones. [21] A diet of fruits, vegetables, whole grains, and low-fat meat and dairy products, avoiding foods with high levels of refined sugars and salt is recommended. [22] Epidemiology [en.wikipedia.org]

The epidemiology of giant cell arteritis: a 12-year retrospective study. Ophthalmology 108: 1145-1149, 2001. [PubMed: 11382644] [Full Text: https://linkinghub.elsevier.com/retrieve/pii/S0161-6420(01)00574-7] Pache, M., Kaiser, H. [omim.org]

Epidemiology The Horton's Disease is the most prominent vasculitis in adults older than 50 years, with peak of incidence between 70 and 80 years (3), and it's of about 200 cases per 100.000 inhabitants, specially in the old-aged, and the age average of [arquivosdeorl.org.br]

Pathophysiology

The first chapter stresses the etiology and pathophysiology of childhood stroke as the basis for evaluations and treatment. [books.google.com]

Giant cell arteritis: a review of classification, pathophysiology, geoepidemiology and treatment. Autoimmun Rev. 2012;11:A544–A554. [PubMed] [Google Scholar] 2. Nesher G, Oren S, Lijovetzky G, Nesher R. [ncbi.nlm.nih.gov]

Prevention

[…] migration of neutrophils and phagocytes into gouty joints Binds to tubulin to result in depolymerisation of microtubules and reduced cell motility Prevents release of inflammatory products by these cells by preventing/limiting phagocytosis of urate crystals [brainscape.com]

Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients. ‎ [books.google.com]

Founded in 1896, Roche continues to search for better ways to prevent, diagnose and treat diseases and make a sustainable contribution to society. [roche.com]

The rheumatologist's role in the treatment of giant cell arteritis Giant cell arteritis can be hard to detect and requires prompt treatment to prevent complications, especially loss of vision. [rheumatology.org]

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