Presentation
Children usually present with a mildly painful mass, which prompts diagnostic imaging studies. The rarity of this condition often presents a diagnostic challenge. Correct diagnosis is crucial in guiding surgical management. [link.springer.com]
Underlying cortical erosion is present, without evidence of medullary involvement. [emedicine.medscape.com]
The tumor most frequently occurs in young adults, with patients presenting in their 20s to 40s. [appliedradiology.com]
Cervical chondromas are rare, benign cartilaginous tumors that may present with spinal cord or nerve root compression. They are more complex when they present in patients with co-existing spinal deformities. [cureus.com]
1 Periosteal Chondroma of the Radial Diaphysis-Rare Presentation and Review of Literature. 61 33364706 2020 2 Quantitative bone SPECT/CT applications for cartilaginous bone neoplasms. 61 Kitajima K...Yamakado K 32716404 2020 3 Periosteal chondroma of [malacards.org]
Entire Body System
- Pain
Clinically, presentation of a juxtacortical chondroma may be with a firm, nonmobile, slowly growing, palpable mass that may have pain that increases with lesion size. [medical-dictionary.thefreedictionary.com]
The patient’s radicular pain resolved and neck pain improved postoperatively but she still has some left sided neck pain and hand dysesthesias that are controlled with oral medication one year following surgery. [cureus.com]
Mild pain and a palpable mass were present in all seven children. Plain radiographs were available in 6/7, MR in 7/7, CT in 4/7 and skeletal scintigraphy in 5/7 children. [link.springer.com]
Only 2.2% of benign tumors and 0.5% of all tumors are juxtacortical chondromas.2 Clinically, presentation of a juxtacortical chondroma may be with a firm, nonmobile, slowly growing, palpable mass that may have pain that increases with lesion size. [appliedradiology.com]
[…] wall (Indian J Thorac Cardiovasc Surg 2019;35:101) 39 year old man with a pelvic mass (Int J Burns Trauma 2020;10:174) 54 year old woman presented with difficulty ambulating and worsening cognition (Cureus 2018;10:e2099) 55 year old woman with neck pain [pathologyoutlines.com]
Musculoskeletal
- Fracture
[…] with histological findings. 61 Nishio J...Naito M 26137286 2015 18 Periosteal chondroma of the femur: A case report and review of the literature. 61 Zheng K...Xu M 25789014 2015 19 Extensive Periosteal Chondroma in the Middle Phalanx with Pathological Fracture [malacards.org]
Of note, an area of more pronounced cortical thinning and a cortical break in its outer portion was suggestive of a pathologic fracture. There was no visualized soft-tissue component, with the surrounding soft tissues appearing normal (Figure 2). [appliedradiology.com]
Neurologic
- Confusion
[…] that are well circumscribed; - lesion is usually hypocellular and well circumscribed; - isolated areas of increased cellularity may be seen; - lesion is composed of benign cartilage but it looks more active than an enchondroma; - this lesion may be confused [wheelessonline.com]
While the lesion is composed of benign cartilage, the appearance is more active than an enchondroma, and may be confused with chondrosarcoma. [appliedradiology.com]
Workup
[…] describing patients treated with less than wide margins include only few lesions in this location, indicating the difficulty of making the diagnosis on radiographs when the lesion involves a different bone. [27] MRI should be performed as part of the initial workup [emedicine.medscape.com]
Treatment
Although the recommended treatment is simple curettage or marginal excision, the reported recurrence rate is significantly higher for lesions in the hand than those in other locations and recurrences only occurred in patients who had local treatments [journals.sagepub.com]
[…] lesion is usually hypocellular and well circumscribed; - isolated areas of increased cellularity may be seen; - lesion is composed of benign cartilage but it looks more active than an enchondroma; - this lesion may be confused with chondrosarcoma; - Treatment [wheelessonline.com]
Local excision is often the treatment of choice. Once resected lesions usually do not recur. [radiopaedia.org]
However, the chondrocytes also may demonstrate some atypia. [14] Treatment consists of wide surgical resection. The Mayo Clinic series reported an 80% survival rate with surgical treatment. [emedicine.medscape.com]
Treatment is currently surgical resection with wide marginal excision including underlying cortex, without capsular disruption, to prevent recurrence. [appliedradiology.com]
Prognosis
Due to differences in aggressiveness and long-term prognosis, this distinction impacts initial treatment. [emedicine.medscape.com]
[…] characteristics include 8: T1: typically iso to low signal relative to muscle T2/T2*: high signal but with low signal areas representing calcification T1 C+ (Gd): heterogeneous and tends to show peripheral predominant contrast enhancement Treatment and prognosis [radiopaedia.org]
Etiology
Introduction: Chondroma is a benign neoplasm of mesenchymal origin and of unknown etiology, very infrequently appearing in the soft tissues due to its constitution of mature cartilage cells without bone; however, they usually present focal calcifications [es.glosbe.com]
Discussion Etiology Chondromas are uncommonly seen in the cervical spine. A recent review of the literature indicates there have been 18 reported cases of cervical chondroma since 1960 [4]. [cureus.com]
Epidemiology
[…] hyaline cartilage No connection with medullary cavity (radiologically) Terminology Juxtacortical chondroma, subperiosteal chondroma ICD coding ICD-O: 9221/0 - periosteal chondroma ICD-11: 2E82 & XH3BC3 - benign chondrogenic tumors & periosteal chondroma Epidemiology [pathologyoutlines.com]
Pathophysiology
[…] and young adults, predominantly < 30 years of age (Oncol Lett 2015;9:1637) M:F = 1.5:1 Sites Small bones of the hands and long bones of the skeleton, particularly proximal metaphyseal or diaphyseal regions of humerus and femur (Oncol Lett 2015;9:1637) Pathophysiology [pathologyoutlines.com]
Prevention
[…] cellularity may be seen; - lesion is composed of benign cartilage but it looks more active than an enchondroma; - this lesion may be confused with chondrosarcoma; - Treatment: - most of these lesions present in stage 2 & require en bloc marginal excision to prevent [wheelessonline.com]
Surgical fusion with instrumentation following tumor resection was necessary in this case to restore cervical lordosis, prevent further kyphosis, re-align, and stabilize the spine. [cureus.com]
Treatment is currently surgical resection with wide marginal excision including underlying cortex, without capsular disruption, to prevent recurrence. [appliedradiology.com]