Thirty-eight patients presented with previously untreated, predominantly low-grade juxtacortical osteosarcoma. There were 12 (32%) men and 26 (68%) women with a mean age of 28.9 years. [miami.pure.elsevier.com]

Pain in the affected site was the second most frequent clinical finding, present in 16 (69.6%) patients; five of these latest presented only pain. [scielo.br]

Clinical Presentation Signs/Symptoms: Painless slowly enlarging firm immobile mass in an extremity (most commonly posterior distal thigh/popliteal fossa behind the knee) Mass may be present for several years (usually for more than a year and some patients [tumor-surgery.org.stage.maddevelopment.com]

Varun PowerPoint Presentation: Dr. Varun PowerPoint Presentation: Dr. [authorstream.com]

• Trismus

  Figure 5: Histopathology slide showing highly cellular areas and plump osteoblasts (H&E, 40×) Click here to view Within 2 weeks of the biopsy, the patient developed trismus and increasing pain in the same region. [amsjournal.com]

• Bone Pain

  Patients usually present with bone pain, occasionally accompanied by a soft-tissue mass or swelling. At times, the first symptoms are related to pathologic fracture. [radiologykey.com]

  […] with nerve involvement or pelvic obstruction Cervico occipital region ® head aches, pain and visual problems Sacrococcygeal 70% ® pain and paraesthesia X-Rays Large osteolytic lesion in the midline May contain flecks of calcification Marked bone destruction [flinders.edu.au]

• Knee Pain

  Because of the location in the popliteal fossa, the patient may note inability to flex the knee. Pain is the second most important symptom, and patients may present with pain without having noted a lump. [musculoskeletalkey.com]

• Bone Disorder

  Second most common bone disorder after osteoporosis. 70-90% of persons with Paget disease are asymptomatic. Study the images and then continue reading. [radiologyassistant.nl]

• Osteopenia

  Generalised osteopenia, scleorsis of phalangeal tufts, focal/generalised sclerosis. MRI shows bone marrow granulomas with high T2, intermediate T1, enhancement (DDx mets). [radnotes.co.nz]

[…] describing patients treated with less than wide margins include only few lesions in this location, indicating the difficulty of making the diagnosis on radiographs when the lesion involves a different bone. [27] MRI should be performed as part of the initial workup [emedicine.medscape.com]

Bone lesion workup – If it appears non-aggressive on XR then no further workup required. If appears aggressive, then bone scan (?polyostotic), chest CT (?mets), MRI and biopsy. [radnotes.co.nz]

A diagnosis of parosteal osteosarcoma (POS) at the femoral diaphysis was made following a diagnostic workup. Previous reports of long bone diaphyseal POS are rare. [spandidos-publications.com]

Full-color photomicrographs help you identify pathologic elements and provide correct diagnoses and treatment plans. Boxes and tables offer clear, at-a-glance information on the clinical features, diagnosis, and treatment for many conditions. [books.google.com]

A case report. 61 Chen G...Dai M 30633158 2019 10 A rare rib lesion due to parosteal osteosarcoma: a case report. 61 Tozum H...Kilic B 30670083 2019 11 Osteosarcoma in patients below 25 years of age: An observational study of incidence, metastasis, treatment [malacards.org]

Journal of Orthopaedics and Traumatology 7(4): 198-200, 2006 Juvenile primary lung cancer in a 17-year-old girl as a 2nd malignant neoplasm after osteosarcoma treatment in childhood. Kyobu Geka. [eurekamag.com]

Treatment Surgical Treatment No surgery is indicated; the main role of the consulting surgeon is to exclude other diagnostic possibilities. Prognosis Observed lesions rarely progress. [oncohemakey.com]

Osteosarcoma is a highly malignant tumour which despite modern surgery and chemotherapy still retains a relatively poor prognosis. This prognosis is, however, much better in the rare variant known as juxtacortical osteosarcoma. [ncbi.nlm.nih.gov]

Prognosis Generally good—80% 5-year survival; recurrence with dedifferentiation significantly worsens the prognosis. [medical-dictionary.thefreedictionary.com]

The prognosis of Parosteal Osteosarcoma depends on the stage of cancer; higher grade osteosarcomas indicate a poorer prognosis Osteosarcomas are classified in several different ways. [dovemed.com]

bone surface tumors – better prognosis Dr. [authorstream.com]

This prognosis is, however, much better in the rare variant known as juxtacortical osteosarcoma. [semanticscholar.org]

 Definition Introduction and brief history Epidemiology Etiology Pathology Classification 2.  A mesenchymalmalignancy thatdifferentiates toproduce osteoid is anosteosarcoma nomatter how muchosteoid is produced OsteoidDeposition 3.  Malignant [slideshare.net]

[…] blood CF cerebrospinal fluid CI chemically induced CH chemistry CL classification CO complications CN congenital DI diagnosis DG diagnostic imaging DH diet therapy DT drug therapy EC economics EM embryology EN enzymology EP epidemiology EH ethnology ET etiology [decs.bvs.br]

The etiology is thought to be related to repetitive trauma, similar to tug lesions elsewhere in the body. It is, therefore, also called an avulsive cortical irregularity. [roentgenrayreader.blogspot.com]

Expanded sections on etiology, treatment, and diagnosis of oral cancer (HPV) describe how subtypes can play an important role in the development and natural history of some head and neck cancers, most notably those arising in the oropharynx. [books.google.com]

Pathogenesis Etiology is unknown. [oncohemakey.com]

English: BS blood supply BL blood CF cerebrospinal fluid CI chemically induced CH chemistry CL classification CO complications CN congenital DI diagnosis DG diagnostic imaging DH diet therapy DT drug therapy EC economics EM embryology EN enzymology EP epidemiology [decs.bvs.br]

Epidemiology Most often found in adults undergoing testing for other reasons, although presumably develops at a younger age during skeletal maturation No gender predilection or inheritance pattern Distribution Found within cancellous bone Preference for [oncohemakey.com]

 Definition Introduction and brief history Epidemiology Etiology Pathology Classification 2.  A mesenchymalmalignancy thatdifferentiates toproduce osteoid is anosteosarcoma nomatter how muchosteoid is produced OsteoidDeposition 3.  Malignant [slideshare.net]

126 : pulmonary metastase of an osteosarcoma Case 115 : chondroblastic osteosarcoma of the calcaneum UI:323 - Osteosarcoma 1 (NOS) UI:856 - Osteosarcoma 2 (NOS) Images Male 17 y/o Osteosarcoma https://twitter.com/ga_torres/status/744913535063494656 Epidemiology [humpath.com]

Osteosarcoma incidence and survival rates from 1973 to 2004: data from the Surveillance, Epidemiology, and End Results Program. Cancer 2009;115(7):1531–1543. [pubs.rsna.org]

[…] familial polyposis coli) Osteomas Multiple cutaneous and subcutaneous skin lesions (sebaceous cysts, desmoids, Gardner fibromas) Epidemiology Estimated prevalence: 0.4% Male:female ratio: 2:1 Location: ethmoid and frontal sinuses of the cranium most common Pathophysiology [oncohemakey.com]

Based on these data, close but negative margins may be adequate in achieving local disease control and preventing metastases in these patients. [miami.pure.elsevier.com]

[…] distal femur (thigh bone), in approximately 70% of the cases Parosteal Osteosarcoma presents as a mass with signs and symptoms that include pain and decreased joint movement The exact cause of the condition is unknown and presently, it is not possible to prevent [dovemed.com]

[…] diet therapy DT drug therapy EC economics EM embryology EN enzymology EP epidemiology EH ethnology ET etiology GE genetics HI history IM immunology ME metabolism MI microbiology MO mortality NU nursing PS parasitology PA pathology PP physiopathology PC prevention [decs.bvs.br]

Expanded section on bisphosphonate-related osteonecrosis of the jaws helps you effectively manage patients taking bisphosphonates to prevent bone loss, including information on oral complications, risk factors, and benefits. [books.google.com]

The higher success rate associated with such aggressive surgical resections could be due to two reasons: Wide excision of adjacent bone and periosteum prevents local recurrence by removing small satellite lesions and Overcomes the risk of local spread [amsjournal.com]