Presentation
Discussion In sub-Saharan Africa, where many patients access ART with advanced HIV disease, AIDS-related KS presents with a high tumour burden and rapid disease progression, resulting in a life expectancy of 1 KS involving the lung presents as shortness [sajhivmed.org.za]
Synthesizing disparate information into a readily accessible format, this insightful volume presents state-of-the-art reviews on the basic and clinical features of pulmonary diseases in HIV-infected individuals-informing critical decision making as well [books.google.com]
Case Presentation A 40 year-old HIV positive homosexual male not on HAART Therapy presents with a 1month history of intractable cough, hemoptysis and shortness of breath. [austinpublishinggroup.com]
No evidence of non-Hodgkin lymphoma was present on lymph node or bone marrow biopsies. [acgcasereports.gi.org]
Entire Body System
- Intermittent Fever
He reported intermittent fever and 7-kg weight loss over the past 3 months. On exam he appeared malnourished with oral thrush, and exhibited axillary and inguinal lymphadenopathy. Anal tenderness precluded a digital rectal exam. [acgcasereports.gi.org]
Respiratoric
- Labored Breathing
Pulmonary Kaposi sarcoma occurs when the delicate bronchiole tissue of the lungs are infected, often identified with symptoms of labored breathing and coughing up blood. Pulmonary Kaposi sarcoma is by far the most dangerous form of KS. [disability-benefits-help.org]
Cardiovascular
- Vascular Disease
Hammar Springer Science & Business Media, 29 Jun 2013 - Medical - 1656 pages The first edition of Pulmonary Pathology was dedicated to Vascular Diseases. Vasculitis is so complex as to con two giants in the field, Drs. [books.google.com]
Initial clinical diagnostic impressions included pericarditis, vasculitis due to a collagen vascular disease, interstitial pneumonia, sarcoidosis, and metastatic adenocarcinoma ( n = 13). [nature.com]
Cardiovascular late side effects have been termed radiation-induced heart disease (RIHD) and radiation-induced vascular disease (RIVD). [24] Symptoms are dose dependent and include cardiomyopathy, myocardial fibrosis, valvular heart disease, coronary [en.wikipedia.org]
Workup
In this series, four patients with pericardial effusions were at first thought to have nonneoplastic disease, the workups of whom included two negative bloody pericardial fluid cytology exams, and two patients were initially treated with prednisone for [nature.com]
X-Ray
- Pulmonary Infiltrate
[…] along septa and infiltration of small airways, pulmonary arteries, veins Microscopic (histologic) images Images hosted on PathOut server : Case of the Week #336 : Back to top [pathologyoutlines.com]
Other infections The endemic mycoses can present with pulmonary infiltrates and often have associated mediastinal lymphadenopathy. Imaging characteristics of IPA include nodules, cavitary lesions, and infiltrates. [clinicaladvisor.com]
Kaposi’s sarcoma causing pulmonary infiltrates and respiratory failure in the acquired immunodeficiency syndrome. Ann Intern Med 1985 ;102:471–475. [pubs.rsna.org]
Treatment
About this Kaposi’s Treatment Information The following is a general overview of treatment for Kaposi’s sarcoma. Treatment may consist of surgery, chemotherapy, or a combination of these treatment techniques. [texasoncology.com]
Treatment Options for Kaposi Sarcoma For information about the treatments listed below, see the Treatment Option Overview section. [cancer.gov]
Trials are often designed to treat a certain stage of cancer, either as the first form of treatment offered, or as an option for treatment after other treatments have failed to work. [oncolink.org]
In some treatment centres, it has become the treatment of choice for KS. [cancer.ca]
Response rates are quite high and treatment is well tolerated. Chemotherapy can be used in treatment but there is concern that aggressive treatment might further depress the immune system. [healthcentral.com]
Prognosis
People who take HAART have a better prognosis. [drugs.com]
Certain factors affect prognosis (chance of recovery) and treatment options. The prognosis (chance of recovery) and treatment options depend on the following: The type of Kaposi sarcoma. [rarecancers.org.au]
The KS was controlled with chemotherapy and ongoing HAART. [ 13 ] Prognosis Prognosis depends on the type of KS, status of the patient's immune system, presence of dissemination and whether this is the first appearance of KS or a recurrence. [patient.info]
Patients with only skin involvement, higher CD4 and who are free of HIV-related symptoms have better prognosis. [info.gov.hk]
Depending on the progression of pulmonary Kaposi sarcoma and considering other complications related to AIDS, prognosis for survival of pulmonary Kaposi sarcoma can vary from 4 to 19 months. [disability-benefits-help.org]
Etiology
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10coded.com]
ICD-10-CM Codes › C00-D49 Neoplasms › C45-C49 Malignant neoplasms of mesothelial and soft tissue › Code First Code First Help Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10data.com]
In Lung Cancer, Volume 1: Molecular Pathology Methods and Reviews, leading physicians, scientists, and noted researchers review novel methods for determining the etiology of a variety of lung cancers and present readily reproducible techniques for examining [books.google.com]
Etiology An etiological association with human herpes virus type 8 (HHV8) has been postulated. The AIDS-related and post-transplant variant are associated with immunosuppressive states. [radiopaedia.org]
Epidemiology
A beneficial compendium for those dealing with pulmonary complications of HIV infection, Human Immunodeficiency Virus and the Lung surveys current knowledge on the epidemiology of HIV infection examines HIV's effects on lung cells in addition to immune [books.google.com]
Epidemiology KS is one of the major complications of AIDS [ 10 ]. [ojrd.biomedcentral.com]
Kaposi sarcoma-associated herpes virus-associated malignancies: Epidemiology, pathogenesis, and advances in treatment. Semin Oncol. 2015;42(2):223–46. Article | PubMed PDQ Adult Treatment Editorial Board. [acgcasereports.gi.org]
Franceschi S, Geddes M: Epidemiology of classic Kaposi’s sarcoma, with special reference to Mediterranean population. Tumori 1995; 81:308–314. [karger.com]
Prevention
Prevention There is no way to prevent the milder forms of Kaposi's sarcoma (classic, African, and immunosuppression-related). The most effective way to avoid developing AIDS-related Kaposi's sarcoma is to prevent the spread of HIV. [drugs.com]
Your doctor will prescribe anti-sickness (anti-emetic) drugs to help prevent or control sickness. Take the drugs exactly as your nurse or pharmacist explains to you. It’s easier to prevent sickness than to treat it after it has started. [macmillan.org.uk]
Causes The most likely cause of Kaposi's sarcoma is infection with HHV8 combined with the weakening of defense mechanisms that normally prevent this virus from multiplying. [medbroadcast.com]
How can I prevent Kaposi’s sarcoma? Kaposi sarcoma is caused by the HHV-8 infection. There are no vaccines to protect against it at this point. Preventing the transmission of HHV-8 is the best way to prevent KS. [oncolink.org]
Safer sexual practices can prevent HIV infection. This prevents HIV/AIDS and its complications, including KS. KS almost never occurs in people with HIV/AIDS whose disease is well controlled. Kaposi's sarcoma; HIV - Kaposi; AIDS - Kaposi Habif TP. [medlineplus.gov]