We report a case of a KS in homosexual man with AIDS that was originally presented and diagnosed as UC. We report a 31-year-old homosexual man who presented with rectal pain and bleeding and was found to have Kaposi sarcoma in both skin and rectum. [omicsonline.org]

No evidence of non-Hodgkin lymphoma was present on lymph node or bone marrow biopsies. [ncbi.nlm.nih.gov]

At physical examination he presented with an excellent general state, without skin lesions or palpable adenopathies. Rectal digital examination detected an irregular and painful rectal mass with rough consistence. [scielo.isciii.es]

• Pain

  Despite treatment with HAART, he developed diffuse cutaneous, confluent and nodular red changes in the back, which were 1 cm in diameter, accompanied with pain and itching. During the last four months, he experienced rectal pain and bleeding. [omicsonline.org]

  We report a case of a 24-year-old homosexual man who presented with rectal pain and bleeding and was found to have skin-sparing, disseminated Kaposi’s sarcoma with rectum, liver, lungs, and lymph node involvement. [ncbi.nlm.nih.gov]

  Rectal digital examination detected an irregular and painful rectal mass with rough consistence. [scielo.isciii.es]

• Pleural Effusion

  Despite aggressive measures, his condition continued to deteriorate, leading to pulmonary edema and pleural effusion requiring mechanical ventilation, multi-factorial kidney failure requiring dialysis, anemia, and coagulopathy from worsening liver failure [ncbi.nlm.nih.gov]

• Rectal Pain

  We report a 31-year-old homosexual man who presented with rectal pain and bleeding and was found to have Kaposi sarcoma in both skin and rectum. [omicsonline.org]

  We report a case of a 24-year-old homosexual man who presented with rectal pain and bleeding and was found to have skin-sparing, disseminated Kaposi’s sarcoma with rectum, liver, lungs, and lymph node involvement. [ncbi.nlm.nih.gov]

• Rectal Bleeding

  Leiria, Portugal Case report A 40-year old male patient, professor, without previous relevant medical history searched medical assistance for rectal bleeding for the previous two weeks associated with proctalgia. [scielo.isciii.es]

• Abdominal Pain

  Like in our case, the patients were presented with bloody or watery diarrhea, abdominal pain and weight loss. The majority of cases of gastrointestinal KS (GI-KS) is asymptomatic, and for this reason, remains undiagnosed. [omicsonline.org]

• Rectal Ulcer

  Colonoscopy revealed erythematous rectal mucosa with hemorrhagic nodules and a 3-cm friable necrotic ulcer in the rectum (Figure 1). [ncbi.nlm.nih.gov]

• Pleural Effusion

  Despite aggressive measures, his condition continued to deteriorate, leading to pulmonary edema and pleural effusion requiring mechanical ventilation, multi-factorial kidney failure requiring dialysis, anemia, and coagulopathy from worsening liver failure [ncbi.nlm.nih.gov]

Cases with widespread visceral involvement are commonly poorly responsive to treatment. UC is a chronic inflammatory bowel disease that affects large bowel, causing inflammation and ulcers. [omicsonline.org]

Kaposi sarcoma-associated herpes virus-associated malignancies: Epidemiology, pathogenesis, and advances in treatment. Semin Oncol. 2015; 42(2):223–46. [PMC free article] [PubMed] [Google Scholar] 2. PDQ Adult Treatment Editorial Board. [ncbi.nlm.nih.gov]

Five patients with advanced AIDS received no specific treatment for anorectal KS. Follow-up ranged from 1 month to 5 years. [pubmed.ncbi.nlm.nih.gov]

Non-AIDS asso- ciated Kaposi’s sarcoma: Clinical features and treatment outcome. PLoS ONE. 2011;6(4):e18397. Svrcek M, Tiret E, Bennis M, Guyot P, Fléjou JF. [revistagastrocol.com]

HHV-8 is the main etiological agent of the four clinical-epidemiological forms of KS. [omicsonline.org]

Part 1: Epidemiology, environmental predispositions, clinical manifestations, and therapy. Lancet Infect Dis. 2002;2(5):281-92. Chang Y, Cesarman E, Pessin MS, Lee F, Culpepper J, Knowles DM, et al. [revistagastrocol.com]

KS can have four epidemiological variants: classic, African or endemic, iatrogenic or related to immunosuppressive treatment, and epidemic or AIDS-related [11]. HHV-8 is the main etiological agent of the four clinical-epidemiological forms of KS. [omicsonline.org]

PMID: 8639315 The epidemiology of AIDS-related Kaposi's sarcoma in San Francisco. Rutherford GW, Payne SF, Lemp GF. Rutherford GW, et al. J Acquir Immune Defic Syndr (1988). 1990;3 Suppl 1:S4-7. J Acquir Immune Defic Syndr (1988). 1990. [pubmed.ncbi.nlm.nih.gov]

Kaposi sarcoma-associated herpes virus-associated malignancies: Epidemiology, pathogenesis, and advances in treatment. Semin Oncol. 2015; 42(2):223–46. [PMC free article] [PubMed] [Google Scholar] 2. PDQ Adult Treatment Editorial Board. [ncbi.nlm.nih.gov]