Presentation
We report a case of a KS in homosexual man with AIDS that was originally presented and diagnosed as UC. We report a 31-year-old homosexual man who presented with rectal pain and bleeding and was found to have Kaposi sarcoma in both skin and rectum. [omicsonline.org]
No evidence of non-Hodgkin lymphoma was present on lymph node or bone marrow biopsies. [ncbi.nlm.nih.gov]
At physical examination he presented with an excellent general state, without skin lesions or palpable adenopathies. Rectal digital examination detected an irregular and painful rectal mass with rough consistence. [scielo.isciii.es]
Gastrointestinal
- Rectal Mass
Rectal digital examination detected an irregular and painful rectal mass with rough consistence. [scielo.isciii.es]
- Rectal Bleeding
Leiria, Portugal Case report A 40-year old male patient, professor, without previous relevant medical history searched medical assistance for rectal bleeding for the previous two weeks associated with proctalgia. [scielo.isciii.es]
Skin
- Skin Disease
Many associated skin diseases are more severe in this group. The most common cutaneous infections caused by Staphylococcus aureus especially MRSA that is one of the most important health concerns is antimicrobial resistance [3-6]. [omicsonline.org]
Abstract Visceral involvement in AIDS-related Kaposi’s sarcoma is common, but it is rarely seen in the absence of cutaneous disease. [ncbi.nlm.nih.gov]
Treatment
Cases with widespread visceral involvement are commonly poorly responsive to treatment. UC is a chronic inflammatory bowel disease that affects large bowel, causing inflammation and ulcers. [omicsonline.org]
Kaposi sarcoma-associated herpes virus-associated malignancies: Epidemiology, pathogenesis, and advances in treatment. Semin Oncol. 2015; 42(2):223–46. [PMC free article] [PubMed] [Google Scholar] 2. PDQ Adult Treatment Editorial Board. [ncbi.nlm.nih.gov]
Five patients with advanced AIDS received no specific treatment for anorectal KS. Follow-up ranged from 1 month to 5 years. [pubmed.ncbi.nlm.nih.gov]
Non-AIDS asso- ciated Kaposi’s sarcoma: Clinical features and treatment outcome. PLoS ONE. 2011;6(4):e18397. Svrcek M, Tiret E, Bennis M, Guyot P, Fléjou JF. [revistagastrocol.com]
Etiology
HHV-8 is the main etiological agent of the four clinical-epidemiological forms of KS. [omicsonline.org]
Epidemiology
Part 1: Epidemiology, environmental predispositions, clinical manifestations, and therapy. Lancet Infect Dis. 2002;2(5):281-92. Chang Y, Cesarman E, Pessin MS, Lee F, Culpepper J, Knowles DM, et al. [revistagastrocol.com]
KS can have four epidemiological variants: classic, African or endemic, iatrogenic or related to immunosuppressive treatment, and epidemic or AIDS-related [11]. HHV-8 is the main etiological agent of the four clinical-epidemiological forms of KS. [omicsonline.org]
PMID: 8639315 The epidemiology of AIDS-related Kaposi's sarcoma in San Francisco. Rutherford GW, Payne SF, Lemp GF. Rutherford GW, et al. J Acquir Immune Defic Syndr (1988). 1990;3 Suppl 1:S4-7. J Acquir Immune Defic Syndr (1988). 1990. [pubmed.ncbi.nlm.nih.gov]
Kaposi sarcoma-associated herpes virus-associated malignancies: Epidemiology, pathogenesis, and advances in treatment. Semin Oncol. 2015; 42(2):223–46. [PMC free article] [PubMed] [Google Scholar] 2. PDQ Adult Treatment Editorial Board. [ncbi.nlm.nih.gov]