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Kidney Fibrosarcoma

Presentation

In the present case, the patient was free of symptoms 6 months postsurgery. [ijpmonline.org]

The usual clinical presentation including abdominal mass, haematuria and flank pain are late symptoms. [jcdr.net]

In one research on 17 cases (1), 4 presented lung, liver or bone metastases and evolved to death, 2 presented pelvic recurrence. [scielo.br]

Case presentation A 22-year-old female presented to us with complaints of right flank pain and a large mass in the right side of abdomen for the last 6 months. [afju.springeropen.com]

Abstract A 14-year-old, 7.4 kg, neutered male mongrel dog presented with vomiting, anorexia, and hematuria starting 3 days prior to admission. Serum biochemical profiles indicated severe azotemia. [koreascience.kr]

Entire Body System

  • Malaise

    The constitutional symptoms of weight loss, malaise, anorexia, and anemia were legion in this group of patients.* We have recently seen a primary fibrosarcoma of the kidney in a 69-year-old woman and were stimulated to review the literature and to consider [jamanetwork.com]

Gastrointestinal

  • Left Flank Pain

    […] in the lumbar region RN Vim (+), CK (-), Desmin (-), EMA (-), SMA (-), PAN (-), S100 (-) R – 6 Ares Valdés et al3 53 F 10 Left flank pain, fever and palpable mass RN NS L Brain After 24 months, death Kaneoya et al4 64 F NS Hematuria Nephrectomy NS L [ncbi.nlm.nih.gov]

Liver, Gall & Pancreas

  • Liver Mass

    A liver mass has a different contrast on contrast-enhanced CT (CECT) than a renal origin mass. [clinicalimagingscience.org]

Psychiatrical

  • Suggestibility

    No evidence of filling defect was noted in the inferior vena cava suggesting absence of thrombosis [Figure 3]. [clinicalimagingscience.org]

    Furthermore, a genetic link between sclerosing epithelioid fibrosarcoma and low-grade fibromyxoid sarcoma has been suggested [17]. [diagnosticpathology.biomedcentral.com]

    Malignant fibrous histiocytoma: database review suggests a favorable prognosis in the head and neck. Laryngoscope. 2018;128(4):885–888. doi: 10.1002/lary.26909 [PubMed] [CrossRef] [Google Scholar] 22. Robin YM, Penel N, Pérot G, et al. [ncbi.nlm.nih.gov]

Neurologic

  • Meningism

    Immunohistochemistry and light microscopy can differentiate fibrosarcoma from other meningeal tumors with similar intracranial location and morphology–especially malignant fibrous histiocytoma (MFH), leiomyosarcoma and malignant schwannoma. [ncbi.nlm.nih.gov]

Treatment

There are no standard treatment options available for patient with renal fibrosarcoma. Radical nephrectomy is historically accepted as the main treatment for primary localized renal fibrosarcoma. [ncbi.nlm.nih.gov]

Prognosis

* We have recently seen a primary fibrosarcoma of the kidney in a 69-year-old woman and were stimulated to review the literature and to consider the pathogenesis, prognosis, and therapy of renal fibrosarcomas. [jamanetwork.com]

Prognosis Renal sarcomas have a poor prognosis compared to sarcomas in other localizations. Major prognostic factors are the grading (differentiation) and margin status after resection. [urology-textbook.com]

Renal fibrosarcoma is a highly malignant tumor with poor prognosis, and the etiology of renal fibrosarcoma remains obscure. There are no standard treatment options available for patient with renal fibrosarcoma. [ncbi.nlm.nih.gov]

Etiology

The etiology of renal fibrosarcoma is incompletely understood. It is still lacking in simple and specific tissue-based biomarkers to assist the diagnosis of renal fibrosarcoma. [europeanreview.org]

At present, it is still necessary to carry out basic biology research to better understand etiology and therapeutical strategy of renal fibrosarcoma. [ncbi.nlm.nih.gov]

Epidemiology

Epidemiology 1–2% of all malignant renal tumors. Peak incidence in the fifth decade of life. Pathology of Renal Sarcomas Histology: Leiomyosarcoma is the most common renal sarcoma, followed by liposarcoma. [urology-textbook.com]

Pathophysiology

Currently, there is no evidence-based pathophysiological explanation for the simultaneous occurrence of renal fibrosarcoma and renal pelvic carcinoma in one kidney. We believe that this case has its own characteristics. [ncbi.nlm.nih.gov]

Prevention

Unspecific preoperative findings, associated with its rarity, prevent its early diagnosis. CASE REPORT Male, 27-year old patient, presenting gross hematuria and large abdominal mass. [scielo.br]

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