We report a case of Kimura disease from western Asia, presenting itself as nephrotic syndrome, and this case was seen at a nontransplant kidney presenting with focal segmental glomerulonephritis. [ncbi.nlm.nih.gov]

• Axillary Lymphadenopathy

  A CT chest revealed left axillary lymphadenopathy. The patient was treated with Cryotherapy and there was complete regression of skin lesions, with no recurrence after 1 year of follow-up. [e-ijd.org]

• Cushingoid

  However, symptoms of cushingoid and hirsutism were observed before the patient was removed from the courses of steroids and placed on 10 mg/day of cetirizine to prevent skin lesions;[6] an agent suitable for the treatment of pruritus associated with such [en.wikipedia.org]

• Recurrent Pleural Effusion

  On admission, he had right moderate pleural effusion, but no ascites or any lymph nodal involvement. He developed recurrent pleural effusion and ascites in the ward. [sjmms.net]

• Hypoxemia

  He developed dyspnea and hypoxemia, apparent SVCS, edema of the inferior extremities and recurrent arrhythmia. [bloodjournal.org]

• Pleural Effusion

  On admission, he had right moderate pleural effusion, but no ascites or any lymph nodal involvement. He developed recurrent pleural effusion and ascites in the ward. [sjmms.net]

• Chronic Cough

  The present swelling was not associated with fever, weight loss, and chronic cough. On examination, a globular matted nontender lymphadenopathy was seen extending from posterior auricular to posterior border of the mastoid measuring 4.5 cm × 4 cm. [jcytol.org]

• Hepatojugular Reflux

  Physical examination showed marked edema in the neck and upper chest, and the hepatojugular reflux was positive. There was no change in skin appearance or hepatosplenomegaly. [bloodjournal.org]

• Parotid Mass

  On MR the nodes had high T1-weighted and T2-weighted signal intensities as did portions of the parotid mass. There were suspected flow voids in the parotid mass. The clinical, pathological, and imaging findings are reviewed. [ncbi.nlm.nih.gov]

  Kimura's disease presenting as bilateral parotid masses. Eur Arch Otorhinolaryngol 2005;262:8-10. [ PUBMED ] 2. Kimura T, Yoshimura S, Ishikawa E. On the unusual granulation combined with hyperplastic changes of lymphatic tissue. [jcytol.org]

  Kimura′s disease presenting as bilateral parotid masses. Eur Arch Otorhinolaryngol 2005; 262:8-10. 4. Goldenberg D, Gatot A, Barki Y, Leiberman A, Fliss DM. Computerized tomographic and ultrasonographic features of Kimura′s disease. [ejo.eg.net]

  Our preoperative plan was to perform a lumpectomy, including mass excision with partial parotid gland removal where the mass was in contact with the gland, because the masses were adhered to the parotid gland and facial nerve branches. [e-aps.org]

• Parotid Swelling

  RESULTS: Parotid swelling with inhomogeneities and subcutaneous invasion on magnetic resonance imaging and eosinophils > 10.5 percent in Asian patients clearly indicates Kimura disease. [ncbi.nlm.nih.gov]

  Based on the CT and FNAC findings, an incisional biopsy from the right cheek swelling and image guided biopsy from the left parotid lesion was advised. [jomfp.in]

  Kimura disease manifesting as synchronous bilateral parotid swelling in a young middle-eastern patient. Case Rep Surg 2014;2014:648607. 2. Tseng CF, Lin HC, Huang SC, et al. Kimura’s disease presenting as bilateral parotid masses. [e-aps.org]

• Lip Swelling

  Here, we report a case of a 32-year-old Saudi male presenting with lip mass and epiglottic swelling without any history of hoarse voice or airway compromise. [docksci.com]

• Gingival Swelling

  Recurrent gingival swelling in pregnant women. J Cutan Aesthet Surg 2013; 6: 48-50. 8. Yamamoto T, Minamiguchi S, Watanabe Y, Tsuji J, Asato R, Manabe T, et al. Kimura disease of the epiglottis: a case report and review of literature. [docksci.com]

• Lagophthalmos

  The consequent exophthalmos and lid changes caused lagophthalmos that resulted in severe visual impairment due to chronic bilateral corneal exposure. Kimura's disease may have a devastating effect on visual function. [nature.com]

• Head and Neck Swelling

  Author information 1 Department of Orthopaedics, All India Institute of Medical Sciences, New Delhi 110029, India. [email protected] Abstract Kimura's disease is a rare, chronic inflammatory disorder, presenting usually as head and neck swellings [ncbi.nlm.nih.gov]

  Kiran Rao and Sudesh Kumar, Kimura’s Disease—A Rare Cause of Head and Neck Swelling, International Journal of Otolaryngology and Head & Neck Surgery, 03, 04, (200), (2014). M. Chopinaud, C. Morice, F. Comoz, A. Petit, M. Battistella, A. [dx.doi.org]

  Keywords: Eosinophilic infiltrate, head and neck swelling, Kimura′s disease, lymphoid hyperplasia How to cite this article: Qureshi TA, Siddiqui MI, Tariq MU. Kimura's disease of head and neck: a rare case presentation. [ejo.eg.net]

  Kimura’s disease – A rare cause of head and neck swelling. Int J Otolaryngol Head Neck Surg 2014;3:200-4. Armstrong WB, Allison G, Pena F, Kim JK. Kimura’s disease: Two case reports and a literature review. Ann Otol Rhinol Laryngol 1998;107:1066-71. [surgeryijss.com]

• Facial Mass

  Our preoperative plan was to perform a lumpectomy, including mass excision with partial parotid gland removal where the mass was in contact with the gland, because the masses were adhered to the parotid gland and facial nerve branches. [e-aps.org]

Hence, a thorough workup for the severity and extent of the disease and optimal planning is essential for the successful management of these cases. [ijhas.in]

Pre-excision workup showed blood eosinophilia of >52% with total leukocyte count (TLC) being increased (14 × 10 9 /L). [imjsu.org]

• Toxoplasma Gondii

  Serological tests for HBsAg, anti-HCV, anti-HIV, and antibodies for distoma pulmonala, distoma japonicum, schistosome, bladder worm, sparganum, trichina cystica and filarial were negative, however toxoplasma gondii antibody IgG was positive, while the [bloodjournal.org]

• Non Specific ST-T Changes

  Electrocardiogram showed tall T waves with non-specific ST-T changes. Immediately patient was shifted to intensive care unit, and anti-TB drugs and cyclosporine were withdrawn but prednisolone was continued. [sjmms.net]

• Pleural Effusion

  On admission, he had right moderate pleural effusion, but no ascites or any lymph nodal involvement. He developed recurrent pleural effusion and ascites in the ward. [sjmms.net]

Cetirizine's properties of being effective both in the treatment of pruritus (itching) and as an anti-inflammatory agent make it suitable for the treatment of the pruritus associated with these lesions.[6] In a 2005 study, the American College of Rheumatology [en.wikipedia.org]

We could not see any evidence of relapsing and decided that proper surgical resection of the lesion can be a treatment for KD. [ncbi.nlm.nih.gov]

Two months after the initial treatment, significant reduction in the violaceous colour and the size of palpable nodules was observed. A second treatment was given at 11 J/cm 2. [medicaljournals.se]

The disease has an excellent prognosis, although it may recur locally. [ncbi.nlm.nih.gov]

(Outcomes/Resolutions) The prognosis for Kimura Disease is good with proper treatment. [dovemed.com]

Prognosis ALHE is clinically benign but persistent and treatment is refractory. Kimura, Tetsuji, 20th century Japanese pathologist. Kimura disease - solitary or multiple small benign cutaneous erythematous nodules. [medical-dictionary.thefreedictionary.com]

Abstract Kimura disease is a benign rare chronic inflammatory disorder of unknown etiology that involves the lymph nodes and subcutaneous tissue of the head and neck regions. [ncbi.nlm.nih.gov]

Kimura disease is an uncommon chronic, benign, inflammatory condition of unknown etiology. [medical-dictionary.thefreedictionary.com]

We review the epidemiology, the aetiology and clinical features of this entity. [ncbi.nlm.nih.gov]

Epidemiology Males > females. Young. Asian. Microscopic Features: [2] Angiolymphoid proliferation. Thick walled blood vessels with (plump) hobnail endothelial cells. [3] Eosinophils - abundant - key feature. DDx: Drug reaction. Parasitic infection. [librepathology.org]

EN This article describes Kimura’s disease as a rare case of lymphadenitis and reviews its epidemiology, clinical aspects, diagnosis and treatment methods. The role of surgical procedures was also underlined. [psjd.icm.edu.pl]

KIMURA DISEASE AND ANGIOLYMPHOID HYPERPLASIA WITH EOSINOPHILIA Epidemiology The skin lesions of Kimura disease and angiolymphoid hyperplasia with eosinophilia (AHLE) most commonly affect young to middle-aged adults. [dermaamin.com]

Although the underlying pathophysiology is not clear yet, the diagnosis can be established based on specific histopathological characteristics. [ncbi.nlm.nih.gov]

To date, none of these theories has been substantiated.[1] Pathophysiology[edit] The pathophysiology of Kimura's disease remains unknown, although an allergic reaction, trauma, and an autoimmune process have all been implicated as possible causes. [en.wikipedia.org]

Surgical resection of the lesions can be performed to prevent relapse. Here, the authors report a case of Kimura disease presenting as an eyelid mass in a 13-year-old Asian boy with pronounced eosinophilia and elevated immunoglobulin E levels. [ncbi.nlm.nih.gov]

There is no known prevention for Kimura Disease, as the cause is not fully-understood. [dovemed.com]

Preventing viral outbreaks Some forms of viral keratitis can't be completely eliminated. [mayoclinic.org]