Among the reactive conditions, Kimura disease was considered because of the clinical presentation of a tumorlike swelling in the submandibular subcutaneous area with typical lymphadenopathy. [medical-dictionary.thefreedictionary.com]

We report a case of Kimura disease from western Asia, presenting itself as nephrotic syndrome, and this case was seen at a nontransplant kidney presenting with focal segmental glomerulonephritis. [ncbi.nlm.nih.gov]

• Weight Loss

  Case Report A well-nourished 12 year old girl reported to our Out Patient Department with a history of slowly enlarging painless swelling on left side of neck for past 8 months, not associated with fever, weight loss, cough, loss of appetite and night [medresearch.in]

  There was no h/o fever, cough, weight loss, cough, night sweats or exposure to tuberculosis. He did not have any rash, joint swelling or bone pain. [mjmsr.net]

  The present swelling was not associated with fever, weight loss, and chronic cough. On examination, a globular matted nontender lymphadenopathy was seen extending from posterior auricular to posterior border of the mastoid measuring 4.5 cm × 4 cm. [jcytol.org]

  The patient had no history of fever, cold sweating, or weight loss. During the physical examination, firm and movable masses, measuring up to 3×3×2 cm (the largest one) were found. [kjim.org]

  Correlation with the clinical findings would also help since Kimura's disease usually presents with painless head and neck subcutaneous masses not associated with fever, weight loss, or constitutional symptoms. [ccij-online.org]

• Surgical Procedure

  The role of surgical procedures was also underlined. Kimura disease is a rare and benign chronic inflammatory soft tissue disorder of unknown origin. [psjd.icm.edu.pl]

  The patient refused surgical procedure and opted for application of imiquimod once a day, 5 times a week for 12 weeks, without any improvement of the clinical picture. Fig. 1 Grouped erythematous nodules in the occipital region. [karger.com]

  KD presents as a benign tumor-like lesion or cyst, which may be removed by a surgical procedure ( 9 ). [spandidos-publications.com]

  procedure and hospital stay. [massgeneral.org]

• Rhinitis

  KD is associated with allergic conditions such as asthma, rhinitis, and eczema. We present the cases of 2 patients treated for chronic endogenous eczema and KD in our dermatology clinic. [ncbi.nlm.nih.gov]

  An aberrant allergic response is further supported by the association with asthma, allergic rhinitis and conjunctivitis, atopic dermatitis, and peripheral hypereosinophilia as well as raised serum IgE levels. [4] Most cases have been reported in the dermatology [ijo.in]

  Complications such as atopic dermatitis, allergic rhinitis, asthma, and urticaria occur among patients. [aacijournal.biomedcentral.com]

  Many patients also develop asthma, chronic eczema, pruritus, rhinitis, cutaneous eosinophilic vasculitis, alopecia, and coexisting renal involvement usually presenting as nephrotic syndrome. [2], [7], [9], [12] In the present study, all four individuals [imjsu.org]

  […] development and recurrence may be attributed to a clonal T-cell population. [4] The immune reaction that is believed to be the root of Kimura's disease also predisposes the patient to allergic conditions like asthma, chronic urticaria, pruritis and rhinitis [jomfp.in]

• Hypertension

  The 46 canada goose outlet trillium parka black year old hasn’t been able to work since they’ve been in New York City she has diabetes and hypertension, takes 14 medications a day and uses a walker. [bolibygg.se]

  Abdominal ultrasonography showed no intrahepatic mass, portal hypertension, or splenomegaly. [karger.com]

  Certifications Internal Medicine Gastroenterology Transplant Hepatology Locations Boston: Massachusetts General Hospital Thiim, Michael, MD, MPH Clinical Interests Autoimmune hepatitis Cirrhosis Hepatitis C Hepatitis B Liver failure Liver transplant Portal hypertension [massgeneral.org]

  Longmuir PE, Brothers JA, de Ferranti SD, Hayman LL, Van Hare GF, Matherne GP, Davis CK, Joy EA, McCrindle BW ; on behalf of the American Heart Association Atherosclerosis, Hypertension and Obesity in Youth Committee of the Council on Cardiovascular Disease [ahajournals.org]

• Heart Disease

  […] of Adults With Congenital Heart Disease). [ahajournals.org]

  Small dense low-density lipoprotein-cholesterol concentrations predict risk for coronary heart disease: the Atherosclerosis Risk In Communities (ARIC) study. [journals.plos.org]

• Ulcer

  It is often associated with autoinflammatory disorders (i.e. ulcerative colitis, bronchial asthma) and a co-existing renal disease. [orpha.net]

  Kimura's disease associated with ulcerative colitis: detection of IL-5 mRNA expression of peripheral blood mononuclear cells and colon lesion. Acta Derm Venereol 1998; 78: 375-7. [ispub.com]

  In dendritic (branching) keratitis, or dendritic ulcer, the cornea is inflamed by infection with the herpes simplex (cold sore) virus or herpes zoster (shingles) virus. [britannica.com]

  Colonoscopy revealed dark purple mucosa with multiple ulcers in the cecum and the ascending colon. Biopsy specimens showed a marked hyalinous thickening of the wall of small blood vessels in the mucosa. [onlinelibrary.wiley.com]

• Eruptions

  Three years later, a new eruption, again asymptomatic, appeared in the posterior region of the patient's right ear. Subsequently, she was referred to our department. [ncbi.nlm.nih.gov]

  Eosinophilic dermatosis of myeloproliferative disease: characterization of a unique eruption in patients with hematologic disorders. Arch Dermatol 2001; 137:1378–1380. [link.springer.com]

  Eosinophilia, skin eruption, and dry cough disappeared quickly, whereas digital gangrene of his right thumb and index finger improved gradually ( Figure 6 ). [circ.ahajournals.org]

  It is often accompanied by peripheral blood eosinophilia and elevated serum IgE. [1] [2] [3] [4] Angiolymphoid hyperplasia with eosinophilia (ALHE) is characterized by multiple, small dermal papular or nodular eruptions, which occur in older patients [ijdvl.com]

  The differentiating feature of ALHE lesions are multiple dermal papular or nodular eruption in older patients not frequently associated with eosinophilia. [medresearch.in]

• Skin Rash

  Article First published: 01 October 2003 Abstract We report findings in a Japanese boy with severe skin rash attributable to biotin deficiency. [onlinelibrary.wiley.com]

  The latter is often accompanied by thromboembolic phenomena, persistent dry cough, pulmonary infiltrates, and skin rash. 2 Uncommon location of the nodules, the disappearance of the nodules after initial steroid treatment, an atypical age of the disease [circ.ahajournals.org]

Hence, a thorough workup for the severity and extent of the disease and optimal planning is essential for the successful management of these cases. [ijhas.in]

Pre-excision workup showed blood eosinophilia of >52% with total leukocyte count (TLC) being increased (14 × 10 9 /L). [imjsu.org]

We could not see any evidence of relapsing and decided that proper surgical resection of the lesion can be a treatment for KD. [ncbi.nlm.nih.gov]

Cetirizine's properties of being effective both in the treatment of pruritus (itching) and as an anti-inflammatory agent make it suitable for the treatment of the pruritus associated with these lesions.[6] In a 2005 study, the American College of Rheumatology [en.wikipedia.org]

The disease has an excellent prognosis, although it may recur locally. [ncbi.nlm.nih.gov]

Prognosis ALHE is clinically benign but persistent and treatment is refractory. Kimura, Tetsuji, 20th century Japanese pathologist. Kimura disease - solitary or multiple small benign cutaneous erythematous nodules. [medical-dictionary.thefreedictionary.com]

(Outcomes/Resolutions) The prognosis for Kimura Disease is good with proper treatment. [dovemed.com]

Kimura disease is an uncommon chronic, benign, inflammatory condition of unknown etiology. [medical-dictionary.thefreedictionary.com]

Abstract Kimura disease is a benign rare chronic inflammatory disorder of unknown etiology that involves the lymph nodes and subcutaneous tissue of the head and neck regions. [ncbi.nlm.nih.gov]

We review the epidemiology, the aetiology and clinical features of this entity. [ncbi.nlm.nih.gov]

Epidemiology Males > females. Young. Asian. Microscopic Features: [2] Angiolymphoid proliferation. Thick walled blood vessels with (plump) hobnail endothelial cells. [3] Eosinophils - abundant - key feature. DDx: Drug reaction. Parasitic infection. [librepathology.org]

EN This article describes Kimura’s disease as a rare case of lymphadenitis and reviews its epidemiology, clinical aspects, diagnosis and treatment methods. The role of surgical procedures was also underlined. [psjd.icm.edu.pl]

KIMURA DISEASE AND ANGIOLYMPHOID HYPERPLASIA WITH EOSINOPHILIA Epidemiology The skin lesions of Kimura disease and angiolymphoid hyperplasia with eosinophilia (AHLE) most commonly affect young to middle-aged adults. [dermaamin.com]

Although the underlying pathophysiology is not clear yet, the diagnosis can be established based on specific histopathological characteristics. [ncbi.nlm.nih.gov]

To date, none of these theories has been substantiated.[1] Pathophysiology[edit] The pathophysiology of Kimura's disease remains unknown, although an allergic reaction, trauma, and an autoimmune process have all been implicated as possible causes. [en.wikipedia.org]

The control of hypereosinophilia may contribute to the prevention of thrombosis and its recurrence in patients with Kimura disease. [ncbi.nlm.nih.gov]

There is no known prevention for Kimura Disease, as the cause is not fully-understood. [dovemed.com]

Preventing viral outbreaks Some forms of viral keratitis can't be completely eliminated. [mayoclinic.org]