We report a case of Kimura disease from western Asia, presenting itself as nephrotic syndrome, and this case was seen at a nontransplant kidney presenting with focal segmental glomerulonephritis. [ncbi.nlm.nih.gov]

• Cushingoid

  However, symptoms of cushingoid and hirsutism were observed before the patient was removed from the courses of steroids and placed on 10 mg/day of cetirizine to prevent skin lesions;[6] an agent suitable for the treatment of pruritus associated with such [en.wikipedia.org]

• Parotid Mass

  On MR the nodes had high T1-weighted and T2-weighted signal intensities as did portions of the parotid mass. There were suspected flow voids in the parotid mass. The clinical, pathological, and imaging findings are reviewed. [ncbi.nlm.nih.gov]

  Kimura's disease presenting as bilateral parotid masses. Eur Arch Otorhinolaryngol 2005;262:8-10. [ PUBMED ] 2. Kimura T, Yoshimura S, Ishikawa E. On the unusual granulation combined with hyperplastic changes of lymphatic tissue. [jcytol.org]

  Kimura′s disease presenting as bilateral parotid masses. Eur Arch Otorhinolaryngol 2005; 262:8-10. 4. Goldenberg D, Gatot A, Barki Y, Leiberman A, Fliss DM. Computerized tomographic and ultrasonographic features of Kimura′s disease. [ejo.eg.net]

  Kimura’s disease presenting as bilateral parotid masses. Eur Arch Otorhinolaryngol 2005;262:8–10. 3. Fouda MA, Gheith O, Refaie A, et al. Kimura disease: a case report and review of the literature with a new management protocol. [e-aps.org]

• Parotid Swelling

  RESULTS: Parotid swelling with inhomogeneities and subcutaneous invasion on magnetic resonance imaging and eosinophils 10.5 percent in Asian patients clearly indicates Kimura disease. [ncbi.nlm.nih.gov]

  Fine needle aspiration cytology (FNAC) from the left parotid swelling and lymph nodes, as well as from the right cheek gave the impression of chronic nonspecific lymphadenitis and myoepithelial sialadenitis. [jomfp.in]

  Kimura disease manifesting as synchronous bilateral parotid swelling in a young middle-eastern patient. Case Rep Surg 2014;2014:648607. 2. Tseng CF, Lin HC, Huang SC, et al. Kimura’s disease presenting as bilateral parotid masses. [e-aps.org]

• Neck Swelling

  Author information 1 Department of Orthopaedics, All India Institute of Medical Sciences, New Delhi 110029, India. [email protected] Abstract Kimura's disease is a rare, chronic inflammatory disorder, presenting usually as head and neck swellings [ncbi.nlm.nih.gov]

  Right cheek and neck swellings were the largest, measuring 2 2 and 3 3 cm, respectively, and had been increasing in size for the last 2 years. [ejo.eg.net]

  N Dinesh K, A Manoharan, Kumaran AA, S Balaji, S Sivaraman .Kimura’s Disease - A Rare Cause of Neck Swelling. Pediatr Rev: Int J Pediatr Res 2014;1(2):64-67. doi:10.17511/ijpr.2014.02.02. [medresearch.in]

  Kiran Rao and Sudesh Kumar, Kimura’s Disease—A Rare Cause of Head and Neck Swelling, International Journal of Otolaryngology and Head & Neck Surgery, 03, 04, (200), (2014). M. Chopinaud, C. Morice, F. Comoz, A. Petit, M. Battistella, A. [doi.org]

• Head and Neck Swelling

  Author information 1 Department of Orthopaedics, All India Institute of Medical Sciences, New Delhi 110029, India. [email protected] Abstract Kimura's disease is a rare, chronic inflammatory disorder, presenting usually as head and neck swellings [ncbi.nlm.nih.gov]

  Kiran Rao and Sudesh Kumar, Kimura’s Disease—A Rare Cause of Head and Neck Swelling, International Journal of Otolaryngology and Head & Neck Surgery, 03, 04, (200), (2014). M. Chopinaud, C. Morice, F. Comoz, A. Petit, M. Battistella, A. [doi.org]

  Keywords: Eosinophilic infiltrate, head and neck swelling, Kimura′s disease, lymphoid hyperplasia How to cite this article: Qureshi TA, Siddiqui MI, Tariq MU. Kimura's disease of head and neck: a rare case presentation. [ejo.eg.net]

  Kimura’s disease – A rare cause of head and neck swelling. Int J Otolaryngol Head Neck Surg 2014;3:200-4. Armstrong WB, Allison G, Pena F, Kim JK. Kimura’s disease: Two case reports and a literature review. Ann Otol Rhinol Laryngol 1998;107:1066-71. [surgeryijss.com]

• Facial Mass

  When encountered, it is possible for bilateral symmetric facial masses to be considered as part of the natural shape of a patient’s face because they are not common. [e-aps.org]

Pre-excision workup showed blood eosinophilia of 52% with total leukocyte count (TLC) being increased (14 10 9 /L). [imjsu.org]

Hence, a thorough workup for the severity and extent of the disease and optimal planning is essential for the successful management of these cases. [ijhas.in]

• Albuminuria

  Other rare sites include the axilla, oral cavity, nasal sinuses, and median nerve. [5] Approximately 12-16% of the patients have nephropathy presenting as nephrotic syndrome with albuminuria and increased serum creatinine. [ccij-online.org]

Cetirizine's properties of being effective both in the treatment of pruritus (itching) and as an anti-inflammatory agent make it suitable for the treatment of the pruritus associated with these lesions.[6] In a 2005 study, the American College of Rheumatology [en.wikipedia.org]

We could not see any evidence of relapsing and decided that proper surgical resection of the lesion can be a treatment for KD. [ncbi.nlm.nih.gov]

Another study demonstrated that radiotherapy (20-45 Gy) was more effective than local excision and steroid treatment, with local response rates of 64.3% versus 22.2%, respectively. [emedicine.medscape.com]

The disease has an excellent prognosis, although it may recur locally. [ncbi.nlm.nih.gov]

(Outcomes/Resolutions) The prognosis for Kimura Disease is good with proper treatment. [dovemed.com]

Prognosis ALHE is clinically benign but persistent and treatment is refractory. Kimura, Tetsuji, 20th century Japanese pathologist. Kimura disease - solitary or multiple small benign cutaneous erythematous nodules. [medical-dictionary.thefreedictionary.com]

Abstract Kimura disease is a benign rare chronic inflammatory disorder of unknown etiology that involves the lymph nodes and subcutaneous tissue of the head and neck regions. [ncbi.nlm.nih.gov]

We review the epidemiology, the aetiology and clinical features of this entity. [ncbi.nlm.nih.gov]

Epidemiology Males females. Young. Asian. Microscopic Features: [2] Angiolymphoid proliferation. Thick walled blood vessels with (plump) hobnail endothelial cells. [3] Eosinophils - abundant - key feature. DDx: Drug reaction. Parasitic infection. [librepathology.org]

EN This article describes Kimura’s disease as a rare case of lymphadenitis and reviews its epidemiology, clinical aspects, diagnosis and treatment methods. The role of surgical procedures was also underlined. [psjd.icm.edu.pl]

KIMURA DISEASE AND ANGIOLYMPHOID HYPERPLASIA WITH EOSINOPHILIA Epidemiology The skin lesions of Kimura disease and angiolymphoid hyperplasia with eosinophilia (AHLE) most commonly affect young to middle-aged adults. [dermaamin.com]

Although the underlying pathophysiology is not clear yet, the diagnosis can be established based on specific histopathological characteristics. [ncbi.nlm.nih.gov]

To date, none of these theories has been substantiated.[1] Pathophysiology[edit] The pathophysiology of Kimura's disease remains unknown, although an allergic reaction, trauma, and an autoimmune process have all been implicated as possible causes. [en.wikipedia.org]

Kimura disease may represent a primary inflammatory process with secondary vascular proliferation. [5, 6] Reports have described both diseases presenting simultaneously. [7] Pathophysiology The pathophysiology of Kimura disease remains unknown. [emedicine.medscape.com]

The control of hypereosinophilia may contribute to the prevention of thrombosis and its recurrence in patients with Kimura disease. [ncbi.nlm.nih.gov]

There is no known prevention for Kimura Disease, as the cause is not fully-understood. [dovemed.com]

However, symptoms of cushingoid and hirsutism were observed before the patient was removed from the courses of steroids and placed on 10 mg/day of cetirizine to prevent skin lesions;[6] an agent suitable for the treatment of pruritus associated with such [en.wikipedia.org]