We present a comprehensive and clinically relevant study of the diversity of O- and K-antigen biosynthesis gene clusters across a global collection of over 500 K. pneumoniae whole-genome sequences and the seroepidemiology of human isolates from different [mgen.microbiologyresearch.org]

Patients demonstrate a wide range of presentations with pyelonephritis, ranging from a mild illness to sepsis. Patients usually present with fever, flank or back pain, shaking chills, and irritation related to bladder voiding. [clinicaladvisor.com]

The present study retrospectively analysed the infection trends, resistance patterns, and clonal relationships between isolates of Klebsiella spp. from a tertiary care hospital. [ncbi.nlm.nih.gov]

He had moved to the United States 25 years before presentation. His last visit to Asia was a trip to Vietnam 5 years before presentation. He worked in a restaurant before he became ill. [academic.oup.com]

• Cat Scratch

  […] granulocytic anaplasmosis, Anaplasmosis Ehrlichia chaffeensis Human monocytotropic ehrlichiosis Ehrlichia ewingii Ehrlichiosis ewingii infection Rhizobiales Brucellaceae Brucella abortus Brucellosis Bartonellaceae Bartonellosis: Bartonella henselae Cat-scratch [en.wikipedia.org]

• Pathologist

  Alternative Titles: Friedländer’s bacillus, Klebsiella friedlanderi Learn about this topic in these articles: description In Klebsiella Klebsiella pneumoniae, also called Friedländer’s bacillus, was first described in 1882 by German microbiologist and pathologist [britannica.com]

  Origin of klebsiella New Latin genus name after Edwin Klebs (1834-1913), German-American pathologist born in Königsberg (Kaliningrad) THE AMERICAN HERITAGE® DICTIONARY OF THE ENGLISH LANGUAGE, FIFTH EDITION by the Editors of the American Heritage Dictionaries [yourdictionary.com]

  Klebsiella) of nonmotile enterobacteria that includes causative agents of respiratory and urogenital infections First Known Use of klebsiella 1928, in the meaning defined above History and Etymology for klebsiella New Latin, from Edwin Klebs †1913 German pathologist [merriam-webster.com]

  […] bacteria of the genus Klebsiella, certain species of which, as K. pneumoniae, are found in the respiratory, intestinal, and genitourinary tracts of humans and animals… … Universalium klebsiella — noun Etymology: New Latin, from Edwin Klebs died 1913 German pathologist [medicine.academic.ru]

  [citation needed] Also, it is known as Friedlander's bacillum in honor of Carl Friedländer, a German pathologist, who proposed that this bacterium was the etiological factor for the pneumonia seen especially in immunocompromised individuals such as people [en.wikipedia.org]

• Sneezing

  […] patients also should clean their hands very often, including: Before preparing or eating food Before touching their eyes, nose, or mouth Before and after changing wound dressings or bandages After using the restroom After blowing their nose, coughing, or sneezing [cdc.gov]

  Always wash your hands before you: Eat Touch your eyes, nose, or mouth Change bandages on a cut And wash your handsafter you: Use the bathroom Blow your nose, cough, or sneeze Touch things that might have germs on them, especially in doctor’s offices [webmd.com]

• Pertussis

  […] consisting of 21 different substrates) IgG IgM field A: verification BIOCHIP, RSV, Adenovirus type 3, Influenza virus type A (H1N1 and H3N2) field B: Influenza virus type B, Parainfluenza virus type 1, 2, 3 field C: Parainfluenza virus type 4, Bordetella pertussis [euroimmun.com]

  /Bordetella parapertussis Pertussis γ Enterobacteriales (OX−) Lac+ Klebsiella pneumoniae Rhinoscleroma, Pneumonia Klebsiella granulomatis Granuloma inguinale Klebsiella oxytoca Escherichia coli: Enterotoxigenic Enteroinvasive Enterohemorrhagic O157:H7 [en.wikipedia.org]

• Guillain-Barré Syndrome

  Acinetobacter baumannii Xanthomonadaceae Stenotrophomonas maltophilia Cardiobacteriaceae Cardiobacterium hominis HACEK Aeromonadales Aeromonas hydrophila/Aeromonas veronii Aeromonas infection ε Campylobacterales Campylobacter jejuni Campylobacteriosis, Guillain–Barré [en.wikipedia.org]

• Bartonella Henselae

  henselae Cat-scratch disease Bartonella quintana Trench fever Either B. henselae or B. quintana Bacillary angiomatosis Bartonella bacilliformis Carrion's disease, Verruga peruana β Neisseriales M+ Neisseria meningitidis/meningococcus Meningococcal disease [en.wikipedia.org]

• Neisseria Gonorrhoeae

  […] meningitidis/meningococcus Meningococcal disease, Waterhouse–Friderichsen syndrome, Meningococcal septicaemia M− Neisseria gonorrhoeae/gonococcus Gonorrhea ungrouped: Eikenella corrodens/Kingella kingae HACEK Chromobacterium violaceum Chromobacteriosis [en.wikipedia.org]

• Burkholderia Mallei

  […] pseudomallei Melioidosis Burkholderia mallei Glanders Burkholderia cepacia complex Bordetella pertussis/Bordetella parapertussis Pertussis γ Enterobacteriales (OX−) Lac+ Klebsiella pneumoniae Rhinoscleroma, Pneumonia Klebsiella granulomatis Granuloma [en.wikipedia.org]

• Coxiella Burnetii

  burnetii Q fever Thiotrichales Francisella tularensis Tularemia Vibrionaceae Vibrio cholerae Cholera Vibrio vulnificus Vibrio parahaemolyticus Vibrio alginolyticus Plesiomonas shigelloides Pseudomonadales Pseudomonas aeruginosa Pseudomonas infection [en.wikipedia.org]

• Pleural Adhesions

  These patients have an increased tendency to develop lung abscess, cavitation, empyema, and pleural adhesions. It has a death rate around 50%, even with antimicrobial therapy. [en.wikipedia.org]

  Pleural effusion, empyema, abscess formation, and pleural adhesions occur with increased frequency in patients with Klebsiella pneumonia. [emedicine.medscape.com]

Treatment of Klebsiella pneumonia has discrepant results. [emedicine.medscape.com]

Thaden JT, Pogue JM, Kaye KS: Role of newer and re-emerging older agents in the treatment of infections caused by carbapenem-resistant Enterobacteriaceae. [msdmanuals.com]

Treatment is with antibiotics. Infections with Klebsiella, Enterobacter, and Serratia are often hospital-acquired and occur mainly in patients with diminished resistance. [merckmanuals.com]

Recovery can take several months, but early treatment will improve your prognosis. [healthline.com]

When doctors identify K. pneumoniae in samples quickly and prescribe the appropriate antibiotics right away, the prognosis improves. However, delays in diagnosis and testing are common, and this can lead to a less favorable prognosis. [medicalnewstoday.com]

A small percentage of pneumonias have as their etiologic agent Klebsiella pneumoniae, an organism belonging to the Friedländer group. Bullowa reports this organism as the causative agent in 1.1 per cent of 4,416 cases of pneumonia. [jamanetwork.com]

Species include K. pneumo´niae (also called K. friedlän´deri ), the etiologic agent of Friedländer's pneumonia ; K. pneumo´niae ozae´nae, which occurs in ozena and other respiratory diseases; and K. rhinosclero´matis, a species isolated from patients [medical-dictionary.thefreedictionary.com]

Etiology: Klebsiella pneumoniae is a Gram-negative facultatively anaerobic non spore-forming rod. K. pneumoniae has not been recognized as a primary pathogen. Incidence: The incidence of infection is rare. [dora.missouri.edu]

A recent publication by Elikwu et al., (2017) on etiology and antimicrobial susceptibility patterns from urinary tract infections in Nigeria described that of all bacteria isolated from urine samples only 4% were caused by ESBL. [ncbi.nlm.nih.gov]

The two isolates were identical as determined by ribotyping and pulsed-field gel electrophoresis, and they differed from 10 epidemiologically unrelated strains. [ncbi.nlm.nih.gov]

Its polysaccharide capsule is a major virulence determinant and epidemiological marker. However, little is known about capsule epidemiology since serological typing is not widely accessible and many isolates are serologically non-typeable. [mgen.microbiologyresearch.org]

DISCUSSION Epidemiology The genus Klebsiella is a member of the Enterobacteriaceae family. [nature.com]

Epidemiology and resistance phenotypes of carbapenemase-producing Klebsiella pneumoniae in Greece, 2014 to 2016. [eurosurveillance.org]

Mikulicz cells observed during Klebsiella rhinoscleromatis infection However, despite their clinical importance, many facets of the pathophysiology of Klebsiella pneumoniae remain unknown. [research.pasteur.fr]

Lactose fermenting, indole positive Many anatomic and environmental sources Opportunistic pathogenic, multiple sites Antibiotic associated hemorrhagic diarrhea Cytotoxin Frequently antibiotic resistant, including extended spectrum beta lactamases (ESBLs) Pathophysiology [pathologyoutlines.com]

Objectives: Describe the pathophysiology of Klebsiella. Identify the most common cause of hospital-acquired pneumonia in the United States. Recall patients most likely to get Klebsiella pneumonia. [ncbi.nlm.nih.gov]

The development of new therapeutic strategies requires a better understanding of K. pneumoniae pathophysiology in the context of the complex interactions between the microbe and our body. [healio.com]

Preventing Klebsiella from spreading To prevent spreading Klebsiella infections between patients, healthcare personnel must follow specific infection control precautions (see: Guideline for Isolation Precautions: Preventing Transmission of Infectious [cdc.gov]

Centers for Disease Control and Prevention. Retrieved from https://www.cdc.gov/mmwr/preview/mmwrhtml/mm5810a4.htm [nursesed.net]