Presentation
He presented significant improvement after 72h. [bjid.org.br]
The present study was designed to determine the virulence factors and antibiogram of klebsiellae, isolated from various clinical specimen in a tertiary care hospital of West Bengal, India. [ncbi.nlm.nih.gov]
It had irregular and mildly indurated margins, was painful on palpation and its floor was granulated and a mild exudate was present (Figure 1). The presumptive diagnosis was that of a squamous cell carcinoma. [forp.usp.br]
The sequencing of all bacterial genetic material present showed that all three Klebsiella species were sharing drug-resistance genes amongst themselves -- including at least two genes that code for powerful enzymes that disable a broad spectrum of penicillin-like [sciencedaily.com]
Associated factors significant in multivariable analysis are presented in Table 2, and univariate analyses are shown in S3 Table. [journals.plos.org]
Immune System
- Splenomegaly
Upon admission, the patient was in good general condition with widespread jaundice tone, abdomen with no evidence of neither hepato nor splenomegaly or peritoneal irritation; normal upper and lower extremities with capillary refill of 2s. [bjid.org.br]
Entire Body System
- Fever
Symptoms include chest pain when you breathe or cough, fever and chills, shortness of breath, fatigue, a cough that may produce phlegm, and changes in mental awareness. [everydayhealth.com]
[…] your kidneys, you might have: fever chills nausea vomiting pain in your upper back and side You can experience an upper or a lower UTI. [healthline.com]
Teach your family about fever and other signs of infection so they can call for help quickly. [webmd.com]
Tick-borne Rickettsia rickettsii Rocky Mountain spotted fever Rickettsia conorii Boutonneuse fever Rickettsia japonica Japanese spotted fever Rickettsia sibirica North Asian tick typhus Rickettsia australis Queensland tick typhus Rickettsia honei Flinders [en.wikipedia.org]
About 48h after, he had developed fever (38°C) with chills and increased irritability. The physical evaluation revealed, rash and purple lesions on chest and extremities. [bjid.org.br]
- Pain
Symptoms include chest pain when you breathe or cough, fever and chills, shortness of breath, fatigue, a cough that may produce phlegm, and changes in mental awareness. [everydayhealth.com]
If you do have symptoms, you might experience: frequent urge to urinate pain and burning when urinating bloody or cloudy urine passing small amounts of urine pain in your back or pelvic area discomfort in your lower abdomen fever If you have a UTI in [healthline.com]
It is painful, disabling, costly and it lacks definitive treatment guidelines. Klebsiella spp. are uncommon causes of Total Hip Arthroplasty. [online.boneandjoint.org.uk]
The size, depth, outline, base, aspect of the floor, pain, time of evolution and resolution of oral ulcers are discussed. [forp.usp.br]
For example, if the bacteria gives you pneumonia, you may have: Fever Cough Chest pain Trouble breathing More mucus, which may be thick and bloody Klebsiella pneumoniae can hit other parts of your body, too. [webmd.com]
- Fatigue
Symptoms include chest pain when you breathe or cough, fever and chills, shortness of breath, fatigue, a cough that may produce phlegm, and changes in mental awareness. [everydayhealth.com]
K. pneumoniae wound infections include: cellulitis necrotizing fasciitis myositis Depending on your type of infection, you might experience: fever redness swelling pain flu-like symptoms fatigue wounds or ulcers, which are sores on the lining of your [healthline.com]
- Recurrent Infection
Three patients had recurrent infections involving different sites, 2 (16%) died of fulminant septicemia, and 3 (25%) had significant permanent neurological deficits. [ncbi.nlm.nih.gov]
- Asymptomatic
Full Text A three-day-old male with asymptomatic jaundice was admitted to the hospital. First-born by vaginal delivery to a young mother at 39 weeks of gestation; Apgar 9/9, weight 2850g, height 50cm, no history of chronic diseases. [bjid.org.br]
Respiratoric
- Pertussis
/Bordetella parapertussis Pertussis γ Enterobacteriales (OX−) Lac+ Klebsiella pneumoniae Rhinoscleroma, Pneumonia Klebsiella granulomatis Granuloma inguinale Klebsiella oxytoca Escherichia coli: Enterotoxigenic Enteroinvasive Enterohemorrhagic O157:H7 [en.wikipedia.org]
Liver, Gall & Pancreas
- Jaundice
Full Text A three-day-old male with asymptomatic jaundice was admitted to the hospital. First-born by vaginal delivery to a young mother at 39 weeks of gestation; Apgar 9/9, weight 2850g, height 50cm, no history of chronic diseases. [bjid.org.br]
Skin
- Cutaneous Manifestation
Nosocomial infections with resistant Gram-negative organisms, particularly strains of K. pneumoniae, have become a significant problem.1 However, cutaneous manifestations are considered as atypical manifestations; Viswanathan et al.2 reported neonatal [bjid.org.br]
Neurologic
- Irritability
About 48h after, he had developed fever (38°C) with chills and increased irritability. The physical evaluation revealed, rash and purple lesions on chest and extremities. [bjid.org.br]
Because this was a long-term ulcerated lesion which was exposed to local irritant factors and intense sunlight, and also considering that it was disturbing the normal daily life of the patient, the lesion was excised using a CO2 laser (Sharplan 20C, Laser [forp.usp.br]
Workup
Serum
- Leukopenia
Routine blood exams showed leukopenia and total bilirubin of 17.9mg/dl. He was managed with continuous blue light therapy. About 48h after, he had developed fever (38°C) with chills and increased irritability. [bjid.org.br]
Treatment
The frequency of Klebsiella infections in the urological wards dropped significantly after up-grading the treatment room, improving catheter storage and reducing ampicillin use. [ncbi.nlm.nih.gov]
Treatment Klebsiellainfections can be dangerous, so doctors start treatment with antibiotics right away. Examples include cephalosporins (cefotaxime and ceftriaxone) and carbapenems (imipenem or cilastatin). [webmd.com]
It is painful, disabling, costly and it lacks definitive treatment guidelines. Klebsiella spp. are uncommon causes of Total Hip Arthroplasty. [online.boneandjoint.org.uk]
If a doctor notices that a bacterial infection persists after the initial treatment, they may order tests to identify the specific bacteria responsible. The results help them choose the most appropriate antibiotic treatment. [medicalnewstoday.com]
Therefore, the probability of antibiotic treatment of Klebsiella infections is weak (12). 2. [genecelltissue.com]
Prognosis
When doctors identify K. pneumoniae in samples quickly and prescribe the appropriate antibiotics right away, the prognosis improves. However, delays in diagnosis and testing are common, and this can lead to a less favorable prognosis. [medicalnewstoday.com]
Prognosis The prognosis of Klebsiella pneumonia is poor, especially in patients who are alcoholic, diabetic, have nosocomial infection or septicemia. Mortality from this type of pneumonia is above 50%. [ncbi.nlm.nih.gov]
Herein, we analyzed risk factors and prognosis in invasive infections caused by KP versus EC, in an area with low antimicrobial resistance. [journals.plos.org]
Etiology
Microbial etiology in hospitalized North Indian adults with community-acquired pneumonia. Lung India. 2018 Mar-Apr;35(2):108-115. [PMC free article: PMC5846258] [PubMed: 29487244] 8. [ncbi.nlm.nih.gov]
[citation needed] Also, it is known as Friedlander's bacillum in honor of Carl Friedländer, a German pathologist, who proposed that this bacterium was the etiological factor for the pneumonia seen especially in immunocompromised individuals such as people [en.wikipedia.org]
Epidemiology
The extensive epidemiologic investigation carried out included a case-control study, careful review of aseptic technique, and cultures from nursery staff and environment. [ncbi.nlm.nih.gov]
WCHKl090001 [GN:klw] Other DBs ICD-11: CA40.03 ICD-10: A49.8 B96.1 J15.0 MeSH: D007710 Reference PMID:21653305 Authors Gupta N, Limbago BM, Patel JB, Kallen AJ Title Carbapenem-resistant Enterobacteriaceae: epidemiology and prevention. [genome.jp]
Carbapenem-resistant Enterobacteriaceae: epidemiology and prevention. Clin Infect Dis. 2011 Jul 1. 53(1):60-7. [QxMD MEDLINE Link]. van Duin D, Bonomo RA. [emedicine.medscape.com]
Pathophysiology
Mikulicz cells observed during Klebsiella rhinoscleromatis infection However, despite their clinical importance, many facets of the pathophysiology of Klebsiella pneumoniae remain unknown. [research.pasteur.fr]
Objectives: Describe the pathophysiology of Klebsiella. Identify the most common cause of hospital-acquired pneumonia in the United States. Recall patients most likely to get Klebsiella pneumonia. [ncbi.nlm.nih.gov]
[…] of the pathophysiology of Klebsiella pneumonia we see neutrophil myeloperoxidase defense against K P. [en.wikipedia.org]
Pathophysiology Host defense against bacterial invasion depends on phagocytosis by polymorphonuclear granulocytes and the bactericidal effect of serum, mediated in large part by complement proteins. [emedicine.medscape.com]
Prevention
Preventing Klebsiella from spreading To prevent spreading Klebsiella infections between patients, healthcare personnel must follow specific infection control precautions (see: Guideline for Isolation Precautions: Preventing Transmission of Infectious [cdc.gov]
Prevention One of the best ways to protect yourself is simple. [webmd.com]
WCHKl090001 [GN:klw] Other DBs ICD-11: CA40.03 ICD-10: A49.8 B96.1 J15.0 MeSH: D007710 Reference PMID:21653305 Authors Gupta N, Limbago BM, Patel JB, Kallen AJ Title Carbapenem-resistant Enterobacteriaceae: epidemiology and prevention. [genome.jp]
^ a b c d e "Guideline for Isolation Precautions: Preventing Transmission of Infectious Agents in Healthcare Settings 2007". Centers for Disease Control and Prevention. [en.wikipedia.org]
Conclusions Monitoring the drug-resistant patterns and risk factors is very important to prevent the dissemination and drug resistance in K. pneumoniae in hospital settings. [genecelltissue.com]