A few minutes later, he regained consciousness but developed chest discomfort, with new-onset ST elevation in leads II, III, and aVF and ST depression in leads I, aVL, and V1 through V3 (Figure). [jamanetwork.com]

He developed constricting chest discomfort associated with dyspnea, sweating and hypotension. [revportcardiol.org]

Kounis syndrome Hypersensitivity myocarditis Cardiac symptoms Acute chest pain - Chest discomfort Dyspnea Palpitations Sudden death Cardiac signs Elevated JVP Irregular pulse Gallop rhythm Electrocardiographic signs Atrioventricular block Left bundle [medscape.com]

A few minutes after administration of the drug, the patient had sudden chest discomfort and pain in the left arm, shortness of breath, sweating and palpitations, generalized erythema and cutaneous rashes that justified admission to Emergency Room. [clinmedjournals.org]

Treatment for anaphylaxis was initiated with intravenous hydrocortisone, diphenhydramine, and famotidine with improvement in pruritus, dyspnea, and chest discomfort. The patient's blood pressure also improved to 120/60 mm Hg. [ncbi.nlm.nih.gov]

Clinical symptoms Acute chest pain Chest discomfort Difficulty in swallowing Dyspnea Faintness Headache Malaise Nausea Pruritus Syncope Vomiting Urticaria Clinical signs Bradycardia or tachycardia Cardiorespiratory arrest Cold extremities Diaphoresis [medscape.com]

The patient presents a coronary syndrome that can manifest as malaise with chest pain of anginal characteristics, and simultaneously also shows symptoms typical of an anaphylactic reaction: hypotension in the context of contact with a known allergen, [medintensiva.org]

[…] was 120/70mmHg, pulse rate was 80 beat per minute, and ECG revealed no abnormalities while the symptom had relieved. 24h Holter (Figs. 11, 12 and 13) revealed ST segment elevation for 2 3 mm in leads II, III, aVF, V5, V6 at 13:40-13:42 (when he felt malaise [bmccardiovascdisord.biomedcentral.com]

He developed facial swelling and hypotension. Emergency medical services found him to be in respiratory distress associated with facial swelling. [ncbi.nlm.nih.gov]

In allergic ACS there may also be specific symptoms relating to the underlying allergic reaction, such as swelling of the face and tongue, wheeze, hives and potentially very low blood pressure (anaphylactic shock).[2] Pathophysiology[edit] In allergy, [en.wikipedia.org]

The patient developed swelling of the face and lips, with severe bronchoconstriction requiring intubation and mechanical ventilation. [joicc.org]

with involvement of the skin, mucosal tissue, or both (eg, generalized urticaria, itching or flushing, swollen lips-tongue-uvula) AND AT LEAST ONE OF THE FOLLOWING: A) Respiratory compromise (eg, dyspnea, wheeze-bronchospasm, stridor, reduced PEF, hypoxemia [ekjm.org]

We present a case of a young woman who experienced attacks of dyspnea, hypoxemia, and hypotension during and after a spinal anesthesia with bupivacaine. [journals.lww.com]

Fentanyl and its derivatives show only limited mast cell activation and may be the option of choice when opiates are required.Oxygen Oxygen should be administered to patients with ACS in the presence of saturation values of under 90%, or a risk of hypoxemia [medintensiva.org]

[…] tissues, surrounding the coronary arteries.[5][6] Signs and symptoms[edit] Acute coronary syndrome (ACS) is usually associated with a constrictive pain in the chest, characteristically with radiation to the neck or the left arm and often associated with pallor [en.wikipedia.org]

[…] symptoms Acute chest pain Chest discomfort Difficulty in swallowing Dyspnea Faintness Headache Malaise Nausea Pruritus Syncope Vomiting Urticaria Clinical signs Bradycardia or tachycardia Cardiorespiratory arrest Cold extremities Diaphoresis Hypotension Pallor [medscape.com]

He developed constricting chest discomfort associated with dyspnea, sweating and hypotension. [revportcardiol.org]

Two hours later, he developed chest pain, dyspnea and diaphoresis. Repeat ECG revealed ST elevation in leads II, III, and aVF with reciprocal changes. He received aspirin and heparin and was taken for coronary angiography. [onlinejacc.org]

Kounis syndrome Hypersensitivity myocarditis Cardiac symptoms Acute chest pain - Chest discomfort Dyspnea Palpitations Sudden death Cardiac signs Elevated JVP Irregular pulse Gallop rhythm Electrocardiographic signs Atrioventricular block Left bundle [medscape.com]

We present a case of a young woman who experienced attacks of dyspnea, hypoxemia, and hypotension during and after a spinal anesthesia with bupivacaine. [journals.lww.com]

Treatment for anaphylaxis was initiated with intravenous hydrocortisone, diphenhydramine, and famotidine with improvement in pruritus, dyspnea, and chest discomfort. The patient's blood pressure also improved to 120/60 mm Hg. [ncbi.nlm.nih.gov]

[…] after exposure to a likely allergen for that patient (minutes to several hours) A) Involvement of the skin-mucosal tissue (eg, generalized urticaria, itch-flush, swollen lips-tongue-uvula) B) Respiratory compromise (eg, dyspnea, wheeze-bronchospasm, stridor [ekjm.org]

[…] pain, nausea and diaphoresis and simultaneously typical symptoms of an anaphylactic reactions in the context of contact with known allergens including hypotension, skin symptoms (rash, urticaria, angioedema), breathing (dyspnoea, wheezing, hoarseness, stridor [signavitae.com]

[…] characteristics, and simultaneously also shows symptoms typical of an anaphylactic reaction: hypotension in the context of contact with a known allergen, skin manifestations (rash, urticaria, angioedema), respiratory alterations (dyspnea, wheezing, dysphonia, stridor [medintensiva.org]

[…] words: Kounis syndrome, Coreopsis atramentaria, acute coronary syndrome Case report A 27-year-old man, with no cardiovascular risk factors and a history of mild persistent asthma, nasal polyps and aspirin allergy, was transferred with dizziness and vomiting [signavitae.com]

Clinical symptoms Acute chest pain Chest discomfort Difficulty in swallowing Dyspnea Faintness Headache Malaise Nausea Pruritus Syncope Vomiting Urticaria Clinical signs Bradycardia or tachycardia Cardiorespiratory arrest Cold extremities Diaphoresis [medscape.com]

It can manifest with a constellation of symptoms, but common manifestations include urticaria, shortness of breath, vomiting, lightheadedness, and low blood pressure. [joicc.org]

Respiratory compromise (eg, dyspnea, wheeze-bronchospasm, stridor, reduced PEF, hypoxemia) C) Reduced blood pressure or associated symptoms (eg, hypotonia [collapse], syncope, incontinence) D) Persistant gastrointestinal symptoms (eg, crampy abdominal pain, vomiting [ekjm.org]

Due to his confusion upon admission, we could only take a detailed history one hour after the initial symptoms, revealing NSAID ingestion (75 mg of diclofenac) for shoulder pain ten minutes before the syncope accompanied by palmoplantar pruritus, vomiting [scielo.br]

[…] symptoms (rash, urticaria, angioedema), breathing (dyspnoea, wheezing, hoarseness, stridor) and/or gastrointestinal (abdominal pain, nausea, vomiting). [signavitae.com]

[…] coronary arteries.[5][6] Signs and symptoms[edit] Acute coronary syndrome (ACS) is usually associated with a constrictive pain in the chest, characteristically with radiation to the neck or the left arm and often associated with pallor, sweatiness, nausea [en.wikipedia.org]

Clinical symptoms Acute chest pain Chest discomfort Difficulty in swallowing Dyspnea Faintness Headache Malaise Nausea Pruritus Syncope Vomiting Urticaria Clinical signs Bradycardia or tachycardia Cardiorespiratory arrest Cold extremities Diaphoresis [medscape.com]

CASE PRESENTATIONS Case 1 A 64-year-old man with known peripheral arterial disease, chronic obstructive pulmonary disease, coronary artery disease, dyslipidemia, and hypertension presented with pruritus, chest pain, dyspnea, and nausea immediately after [ncbi.nlm.nih.gov]

[…] of an anaphylactic reaction: hypotension in the context of contact with a known allergen, skin manifestations (rash, urticaria, angioedema), respiratory alterations (dyspnea, wheezing, dysphonia, stridor) and/or digestive disorders (abdominal pain, nausea [medintensiva.org]

Uniquely, in our patient in addition to acute coronary thrombosis his hospital course was also complicated by acute venous thrombosis and heparin induced thrombocytopenia which may suggest a disorder of inherent coagulopathy behind Kounis syndrome. [cdt.amegroups.com]

Although the pathophysiology of thrombosis of drug-eluting stents is multifactorial, a recent review by Chen et al.2 states that Kounis syndrome can be one of the potential causes. [revespcardiol.org]

Catecholamine increase in patients with angina renders blood platelets more sensitive and more prone to aggregation and thrombosis. Indeed, adrenaline administration has been shown to induce acute drug-eluting stent thrombosis [18]. [tmsforacure.org]

[…] patients with culprit but inactive preexisting atheromatous disease, in whom the allergic insult leads to plaque erosion or rupture, leading to acute myocardial infarction or coronary vasospasm with normal cardiac enzymes type III: coronary artery stent thrombosis [radiopaedia.org]

However, ischemic chest pain continued attacking in the morning during hospitalization. [bmccardiovascdisord.biomedcentral.com]

However the subtle ST- changes and anginal chest pain prompted suspicion for acute coronary syndrome (ACS) then confirmed by a positive troponin. [ahajournals.org]

Approximately 5 minutes after arrival to the hospital, he complained of chest pain, accompanied by nausea and diaphoresis. Urticarial skin lesions appeared, scattered on the trunk and extremities, and syncope ensued with loss of consciousness. [signavitae.com]

The patient continued to have chest pain, and hence, a coronary angiogram was done. Left injection showed mid left anterior descending mild plaque; the patient started developing breathlessness with ST elevation in leads II, III, and aVF. [joicc.org]

Two months later, the patient was again hospitalized with a second episode of syncope arrest and chest pain. In the brain magnetic resonance image, no significant focal intracranial abnormality was detected. [wjgnet.com]

Prolonged hypotension is another pathogenic mechanism for acute coronary syndrome, especially in patients with compromised cardiovascular system. [eusem.org]

While still on the table in the electrophysiology lab, the patient developed hypotension and the monitor showed ST elevations in the inferior leads, as shown in Figure 1. [cureus.com]

Physical examination demonstrated a heart rate of 30 bpm and severe hypotension (60/40 mmHg). [signavitae.com]

He developed constricting chest discomfort associated with dyspnea, sweating and hypotension. [revportcardiol.org]

Five minutes after receiving a vial of intravenous metamizole, she started to show generalized urticaria, chest pain, and intense dyspnea, accompanied by severe hypotension (systolic blood pressure: 70mmHg). [revespcardiol.org]

ST segment elevation ST segment depression T-wave inversion Ventricular tachycardia Laboratory signs Coronary angiography /- - Eosinophilia /- /- Increased cardiac enzymes and especially CPK-MB Increased troponins Cardiomegaly in the chest X-ray /- / [medscape.com]

Physical exam was significant for tachycardia, extensive envenomation and urticaria. Initial electrocardiogram (ECG) revealed no evidence of active ischemia. [onlinejacc.org]

They also induce tachycardia, dysfunctional ventricular contractility and blockade of atrioventricular conduction. [eusem.org]

The initial electrocardiogram showed sinus tachycardia at 120 bpm with ST elevation in the anterior leads. Treatment began with volume replacement, steroids, and intravenous antihistamines. [revespcardiol.org]

[…] leading to plaque rupture and initiation of inflammatory cascade leading to acute thrombus formation.[10] Clinically, anaphylactic reactions occur as a systemic phenomenon, leading to activation of mast cells dwelling in the cardiac tissue producing tachycardia [joicc.org]

We report the case of 57-year-old man, with hypertension and history of allergy, referred for facial rash and palpitations appeared after consumption of canned tuna fish. [tandfonline.com]

Kounis syndrome Hypersensitivity myocarditis Cardiac symptoms Acute chest pain - Chest discomfort Dyspnea Palpitations Sudden death Cardiac signs Elevated JVP Irregular pulse Gallop rhythm Electrocardiographic signs Atrioventricular block Left bundle [medscape.com]

A few minutes after administration of the drug, the patient had sudden chest discomfort and pain in the left arm, shortness of breath, sweating and palpitations, generalized erythema and cutaneous rashes that justified admission to Emergency Room. [clinmedjournals.org]

Clinical effects usually occur within two hours of ethanol ingestion and include; headache, flushing of the face, neck, and trunk, Nausea and vomiting, tachycardia, palpitations, chest pain, dyspnea, marked apprehensiveness, rarely, hypotension, cardiac [signavitae.com]

[…] confusion upon admission, we could only take a detailed history one hour after the initial symptoms, revealing NSAID ingestion (75 mg of diclofenac) for shoulder pain ten minutes before the syncope accompanied by palmoplantar pruritus, vomiting, sweating, palpitations [scielo.br]

He also reported numerous episodes of feeling faint, generalized flushing and skin pruritus that led to repeated assessments at the emergency department. [cmaj.ca]

Treatment for anaphylaxis was initiated with intravenous hydrocortisone, diphenhydramine, and famotidine with improvement in pruritus, dyspnea, and chest discomfort. The patient's blood pressure also improved to 120/60 mm Hg. [ncbi.nlm.nih.gov]

The most commonly reported adverse events were periorbital oedema (1,339), pruritus (1,223), orbital oedema (828), urticarial (594) and rash (532)7. [npra.gov.my]

Clinical symptoms Acute chest pain Chest discomfort Difficulty in swallowing Dyspnea Faintness Headache Malaise Nausea Pruritus Syncope Vomiting Urticaria Clinical signs Bradycardia or tachycardia Cardiorespiratory arrest Cold extremities Diaphoresis [medscape.com]

Due to his confusion upon admission, we could only take a detailed history one hour after the initial symptoms, revealing NSAID ingestion (75 mg of diclofenac) for shoulder pain ten minutes before the syncope accompanied by palmoplantar pruritus, vomiting [scielo.br]

[…] tissue (eg, generalized urticaria, itch-flush, swollen lips-tongue-uvula) B) Respiratory compromise (eg, dyspnea, wheeze-bronchospasm, stridor, reduced PEF, hypoxemia) C) Reduced blood pressure or associated symptoms (eg, hypotonia [collapse], syncope, incontinence [ekjm.org]

Clinical symptoms Acute chest pain Chest discomfort Difficulty in swallowing Dyspnea Faintness Headache Malaise Nausea Pruritus Syncope Vomiting Urticaria Clinical signs Bradycardia or tachycardia Cardiorespiratory arrest Cold extremities Diaphoresis [medscape.com]

Clinical effects usually occur within two hours of ethanol ingestion and include; headache, flushing of the face, neck, and trunk, Nausea and vomiting, tachycardia, palpitations, chest pain, dyspnea, marked apprehensiveness, rarely, hypotension, cardiac [signavitae.com]

pylori infection in patients treated with non-steroidal anti-inflammatory drugs 2008 November;75(5) [ekjm.org]

Fig. 11 ST segment elevation for 2-3 mm in leads II, III, aVF, V5, V6 at13:40-13:42 in Holter Fig. 12 Nonsustained ventricular tachycardia at 13:42 in Holter Fig. 13 Ventricular bigeminy at 13:40 in Holter Discussion We report 5 rare cases of KS induced [bmccardiovascdisord.biomedcentral.com]