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Lactococcus Lactis


Presentation

  • In the present study, the contribution of plasmid-encoded factors to the adhesive and transit properties of the L. lactis subsp. cremoris IBB477 strain was investigated.[ncbi.nlm.nih.gov]
  • Abstract The present work focuses on the role of pili present at the cell surface of Lactococcus lactis in bacterial adhesion to abiotic (hydrophobic polystyrene) and biotic (mucin-coated polystyrene) surfaces.[ncbi.nlm.nih.gov]
  • In the present report, we have shown that non-invasive L. lactis efficiently delivered the newly constructed reporter plasmid pPERDBY to mammalian cells without any chemical enhancers.[ncbi.nlm.nih.gov]
  • These data were presented as mean   SD. We also investigated cumulative days of symptoms regarding infections and fatigue and used Chi-square test for comparison between groups. These data were presented as cumulative number.[ncbi.nlm.nih.gov]
  • We present an atypical case of necrotising pneumonia caused by L. lactis cremoris.[ncbi.nlm.nih.gov]
Down Syndrome
  • Herein, we present the case of a 1-year-old boy with Down syndrome and Hirschprung's disease (HD) who developed a catheter-related bloodstream infection with L. lactis after gastrointestinal surgery.[ncbi.nlm.nih.gov]
Pleural Effusion
  • Abdominal computed tomography (CT) revealed a liver abscess and chest CT showed loculated pleural effusion consistent with empyema. L. lactis cremoris was isolated from culture of the abscess material and blood.[ncbi.nlm.nih.gov]
Sneezing
  • LC-Plasma: URTI positive 39, URTI negative 299; days; p   0.028) and symptoms like sneeze or running nose were significantly lower in the LC-Plasma group (Placebo: Symptom positive 52, Symptom negative 258, vs.[ncbi.nlm.nih.gov]
Abdominal Pain
  • A 42-yr-old man was admitted with fever and abdominal pain. Abdominal computed tomography (CT) revealed a liver abscess and chest CT showed loculated pleural effusion consistent with empyema.[ncbi.nlm.nih.gov]
  • Abstract Irritable bowel syndrome (IBS) is a gastrointestinal disorder characterized by chronic abdominal pain, discomfort, and bloating.[ncbi.nlm.nih.gov]
Regurgitation
  • Abstract We report a case of subacute endocarditis in a 55-year-old patient affected by left atrial myxoma and with a severe mitral regurgitation.[ncbi.nlm.nih.gov]
Chronic Diarrhea
  • In this article, we describe two cases of infection due to L. lactis in patients with chronic diarrhea.[ncbi.nlm.nih.gov]
Periodontitis
  • Abstract Porphyromonas gingivalis, a pathogen involved in the development of chronic periodontitis, has a number of major virulence factors, among which are its surface cysteine protease gingipains.[ncbi.nlm.nih.gov]
  • These results suggest that L. lactis may be a useful probiotic to prevent and treat periodontitis and halitosis. KEYWORDS: L. lactis; antibacterial activity; neutralizing activity; periodontopathogens; probiotics [Indexed for MEDLINE] Free full text[ncbi.nlm.nih.gov]
Halitosis
  • Periodontopathogens induce inflammation and halitosis through the actions of lipopolysaccharide (LPS) and trypsin-like enzymes.[ncbi.nlm.nih.gov]
Hemianopsia
  • A 33-year-old man was admitted with fever, right facial pain, left hemiparesis, and left hemianopsia. Computed tomography demonstrated low density fluid collection in the right falcotentorial subdural space.[ncbi.nlm.nih.gov]
Facial Pain
  • A 33-year-old man was admitted with fever, right facial pain, left hemiparesis, and left hemianopsia. Computed tomography demonstrated low density fluid collection in the right falcotentorial subdural space.[ncbi.nlm.nih.gov]
Meningism
  • Abstract Listeria monocytogenes is a significant food-borne pathogen and the causative agent of listeriosis, a disease which manifests as meningitis in immunocompromised adults or infection of the fetus and miscarriage in pregnant women.[ncbi.nlm.nih.gov]
  • The pathogenesis of streptococcal infections: from tooth decay to meningitis . Nat. Rev. Microbiol. 1 , 219–230 (2003). 5. Tettelin, H. et al. Complete genome sequence of a virulent isolate of Streptococcus pneumoniae .[dx.doi.org]
  • Karanth, Vandana KE, Faisal Hasan and Vasudev Acharya , A Pregnant Woman with Lactococcus lactis Meningitis: To Treat or Not to Treat? , The Journal of Obstetrics and Gynecology of India , 64 , 1 , (63) , (2014) . Anna M.[doi.org]

Workup

Pleural Effusion
  • Abdominal computed tomography (CT) revealed a liver abscess and chest CT showed loculated pleural effusion consistent with empyema. L. lactis cremoris was isolated from culture of the abscess material and blood.[ncbi.nlm.nih.gov]

Treatment

  • Administration of bacterial strains in drinking water was used, respectively, as a preventive or treatment measure, or continuously throughout the study.[ncbi.nlm.nih.gov]
  • Lactococcus lactis subsp. lactis was isolated from blood cultures and infection was eliminated by treatment with amoxicillin-clavulanic acid.[ncbi.nlm.nih.gov]
  • To attain efficient DNA delivery, L. lactis, a non-invasive bacterium is converted to invasive strain either by expressing proteins like Internalin A (InlA) or Fibronectin binding protein A (FnBPA) or through chemical treatments.[ncbi.nlm.nih.gov]
  • After EPS-treatment, a significant reduction in mitochondrial potential was observed, as was nuclear condensation and cell shrinkage. These results may be helpful in further understanding the anti-tumour properties of lactic acid bacteria.[ncbi.nlm.nih.gov]
  • Treatment of cancer cells such as SK-MES-1, DLD-1, HT-29, LoVo, AGS, and MCF-7 cells with 10(6) CFU/well of L. lactis NK34 resulted in strong inhibition of proliferation ( 77% cytotoxicity, p 0.05).[ncbi.nlm.nih.gov]

Prognosis

  • Downregulation of KiSS-1 expression is responsible for tumor invasion and worse prognosis in gastric carcinoma. Int J Cancer. 2004;111:868–72. View Article Google Scholar Ikeguchi M, Yamaguchi K-I, Kaibara N.[doi.org]

Epidemiology

  • Bacteriophages specific to L. lactis cause significant economic losses each year by preventing the bacteria from fully metabolizing the milk substrate. [24] Several epidemiologic studies showed the phages mainly responsible for these losses are from the[en.wikipedia.org]
  • Urwin R, Maiden MC (2003) Multi-locus sequence typing: a tool for global epidemiology. Trends Microbiol 11: 479–487. View Article Google Scholar 33.[doi.org]
  • So far, MLSA and multilocus sequence typing methods have been used primarily in epidemiology including the population analysis of food-related pathogens like Salmonella , Listeria monocytogenes , or Bacillus cereus ( 12 , 33 , 37 ).[dx.doi.org]
Sex distribution
Age distribution

Pathophysiology

  • Physiology and pathophysiology of matrix metalloproteases. Amino Acids. 2011;41:271–90. View Article Google Scholar Giannelli G, Falk-Marzillier J, Schiraldi O, Stetler-Stevenson WG, Quaranta V.[doi.org]

Prevention

  • CONCLUSIONS: We have demonstrated for the first time that L. lactis NZ9000 by itself, is able to prevent 5-FU-induced intestinal inflammation in BALB/c mice.[ncbi.nlm.nih.gov]
  • In conclusion, L. lactis HY 449 may be a useful probiotic for the prevention of dental caries.[ncbi.nlm.nih.gov]
  • No significant effect on eosinophilia was observed when NCC 2287 was given as a preventive or a continuous intervention.[ncbi.nlm.nih.gov]
  • Blocking lead uptake via the gastrointestinal tract is an important prevention strategy.[ncbi.nlm.nih.gov]
  • TNFα-binding L. lactis was less effective than control L. lactis, particularly when TNFα-binding L. lactis was administered in preventive fashion.[ncbi.nlm.nih.gov]

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