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Lanoteplase
7 L Glutamine 245 L Methionine

Presentation

The present study aimed to systematically examine the molecular mechanisms of papillary thyroid cancer (PTC), and identify… Reperfusion treatment in acute myocardial infarction represents the main indication for thrombolytic therapy. [semanticscholar.org]

Design: Seven-centre substudy of the InTIME-I angiographic trial in patients presenting within 6 hours of onset of suspected acute myocardial infarction. [researchwithrutgers.com]

Aims to compare the efficacy and safety of lanoteplase, a single-bolus thrombolytic drug derived from alteplase tissue plasminogen activator, with the established accelerated alteplase regimen in patients presenting within 6 h of onset of ST elevation [einstein.pure.elsevier.com]

Patients (n=602) presenting within 6 hours of acute myocardial infarction were randomized and treated with either a single-bolus injection of lanoteplase (15, 30, 60, or 120 kU/kg) or accelerated alteplase. [jhu.pure.elsevier.com]

Entire Body System

  • Intravenous Administration

    With current results, the advantage of thrombolytic therapy is by earliest restoration of flow due to its quick and simple intravenous administration. [appsread.com]

    […] more bleeding complications than is continuous intravenous infusion. [fqz301.brinkster.net]

Treatment

The difference in the incidence of stroke was not statistically significantly different between the treatment groups (1.89% for lanoteplase and 1.52% for alteplase). [brainkart.com]

Data on 180-day mortality reveal nearly identical results between the two treatment strategies. [acc.org]

The single-bolus regimen should shorten symptoms to treatment times and be especially convenient for emergency department or out-of-hospital administration. (C) 2000 The European Society of Cardiology. [einstein.pure.elsevier.com]

Myocardial Infarction: Symptoms and Treatments. [connection.ebscohost.com]

The present study aimed to systematically examine the molecular mechanisms of papillary thyroid cancer (PTC), and identify… Reperfusion treatment in acute myocardial infarction represents the main indication for thrombolytic therapy. [semanticscholar.org]

Prognosis

The need to have a state of the art overview of the epidemiology,physiopat- logical and electrogenetic mechanisms, diagnosis, pharmacological or electrical treatment,prognosis,patient management in and out of hospital,organisational and economical implications [books.google.com]

Time to treatment influences the impact of ST-segment resolution on one-year prognosis: insights form the assessment of the safety and efficacy of a new thrombolytic (ASSENT-2) trial. Circulation 2001;104(22):2653-9. [pmprb-cepmb.gc.ca]

Although PTC has a favorable prognosis, certain cases exhibit aggressive clinical characteristics, including invasion and metastasis, and the management of PTC remains controversial ( 5, 6 ). [spandidos-publications.com]

The method used to determine the degree and character of coronarosclerosis that matters for the choice of tactics of treatment (indications for coronary artery shunting and angioplastics) and evaluation of prognosis and for diagnostics of malformations [uchika.in.ua]

Epidemiology

The need to have a state of the art overview of the epidemiology,physiopat- logical and electrogenetic mechanisms, diagnosis, pharmacological or electrical treatment,prognosis,patient management in and out of hospital,organisational and economical implications [books.google.com]

NHLBI (National Heart, Lung and Blood Institute) Growth and Health Study NHAAP National Heart Attack Alert Programme NHANES National Health And Nutrition Examination Survey NHBPEP National High Blood Pressure Education Programme NHEFS National Health Epidemiologic [medon-solutio.cz]

Pathophysiology

Gain fresh perspectives and up-to-date insights from the world’s leading authorities on the pathophysiology, diagnosis, and management of stroke. [books.google.de]

Major pulmonary embolism: review of a pathophysiologic approach to the golden hour of hemodynamically significant pulmonary embolism. Chest. 2002;121:877-905. Tan KT, Oudkerk M, van Beek EJR. Deep Vein Thrombosis and Pulmonary Embolism. [activase.com]

Molecular features, pathophysiology and clinical implications. Virchows Arch. 431:1–9. 1997. [spandidos-publications.com]

B, Pathophysiology of HITT. [fqz301.brinkster.net]

Prevention

Stay up to date on hot topics such as mechanisms of action of commonly used drugs, neuronal angiogenesis and stem cells, basic mechanisms of spasm and hemorrhage, prevention of stroke, genetics/predisposing risk factors, and much more. [books.google.de]

Medical therapy Risk factors should be identified and addressed Antihypertensive therapy • To prevent primary and secondary stroke • Treatment if diastolic BP >100mmHg • BP should lowered slowly to avoid any sudden fall in perfusion 9. Contd. [de.slideshare.net]

They are used to open blood vessels and prevent blood clots, and treat high blood pressure or cholesterol. The medicines used will change over time depending on your needs. [cancercarewny.com]

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