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Laryngeal Edema

Edemas Laryngeal


Presentation

  • We present a patient in which direct laryngoscopy was used to distinguish acute laryngeal edema from nonorganic disease.[ncbi.nlm.nih.gov]
  • She was diagnosed with COPD 2 months prior to her presentation and started on treatment with fluticasone propionate and albuterol.[ncbi.nlm.nih.gov]
  • A rare case of a young female with chronic diffuse laryngeal edema causing severe swallowing difficulty is presented. The patient was previously treated with antibiotics and steroids with no improvement.[ncbi.nlm.nih.gov]
  • A possible mechanism by which this complication was produced is discussed and experience with a drug regimen to prevent its occurrence is presented.[ncbi.nlm.nih.gov]
  • Objective: We present a patient in which direct laryngoscopy was used to distinguish acute laryngeal edema from nonorganic disease.[scholars.northwestern.edu]
Hoarseness
  • We here describe two cases whose only symptoms were hoarseness and in which inspection revealed laryngeal edema when the patients ingested any of these substances.[ncbi.nlm.nih.gov]
  • Symptoms of stridor, hoarseness, and tachypnea developed within 24 hours after peeling and subsided within another 24 hours after inhalation therapy with heated aerosol mist was begun. All patients who developed this complication were heavy smokers.[ncbi.nlm.nih.gov]
  • A case report of a woman who had presented to numerous emergency rooms with symptoms of cough, sensation of throat closing, and hoarseness when exposed to odors such as nail polish remover and musk cologne.[ncbi.nlm.nih.gov]
  • Methods: A case report of a woman who had presented to numerous emergency rooms with symptoms of cough, sensation of throat closing, and hoarseness when exposed to odors such as nail polish remover and musk cologne.[scholars.northwestern.edu]
Cough
  • A case report of a woman who had presented to numerous emergency rooms with symptoms of cough, sensation of throat closing, and hoarseness when exposed to odors such as nail polish remover and musk cologne.[ncbi.nlm.nih.gov]
  • Methods: A case report of a woman who had presented to numerous emergency rooms with symptoms of cough, sensation of throat closing, and hoarseness when exposed to odors such as nail polish remover and musk cologne.[scholars.northwestern.edu]
  • METHODS: A case report of a woman who had presented to numerous emergency rooms with symptoms of cough, sensation of throat closing, and hoarseness when exposed to odors such as nail polish remover and musk cologne.[ncbi.nlm.nih.gov]
  • Swelling of the inner ring of the larynx, as a rule, there hoarseness, uncomfortable in phonation, feeling of pressure in the throat, coughing. In diagnosis of laryngeal edema plays a big role indirect (mirror) laryngoscope.[medicalency.com]
  • Symptomatic treatment (eg, cough suppressants, voice rest, steam inhalations) No specific treatment is available for viral laryngitis. Cough suppressants, voice rest, and steam inhalations relieve symptoms and promote resolution of acute laryngitis.[merckmanuals.com]
Hypoventilation
  • The most common adverse respiratory events originating in this setting are airway obstruction, hypoventilation, hypoxemia, and pulmonary aspiration of gastric contents.[ncbi.nlm.nih.gov]
Pleural Effusion
  • Abstract We examined two middle-aged male cousins with unexplained edema of postpubertal onset involving the upper and lower limbs, face, and larynx and, in one of them, a persistent pleural effusion.[ncbi.nlm.nih.gov]
Osteophyte
  • A case of DISH is reported in which excessively enlarged cervical osteophytes led to edema of the laryngeal inlet and consequent severe dyspnea, necessitating emergency tracheotomy.[ncbi.nlm.nih.gov]
Peripheral Neuropathy
  • Her medical history was relevant for undifferentiated connective tissue disorder diagnosed 5 years prior due to a positive antinuclear antibody test, arthralgia, recurrent urticarial skin rash, peripheral neuropathy, abdominal pain, and diffuse body swelling[ncbi.nlm.nih.gov]

Workup

  • […] type III) Acquired C1-INH deficiency Low (type I) Normal or low (type II) ACE inhibitor–induced angioedema 8 simple questions to differentiate HAE from other angioedema 9 Patients who answer “yes” to all or most of the questions may require further workup[allabouthae.com]
Pleural Effusion
  • Abstract We examined two middle-aged male cousins with unexplained edema of postpubertal onset involving the upper and lower limbs, face, and larynx and, in one of them, a persistent pleural effusion.[ncbi.nlm.nih.gov]

Treatment

  • No significant differences were observed between treatment groups in improvement in stridor score or the number of subsequent aerosols required.[ncbi.nlm.nih.gov]
  • NamPhong.Nguyen@yahoo.com Abstract We would like to determine the effectiveness of image-guided radiotherapy (IGRT) to reduce laryngeal edema following treatment for head and neck cancer and to assess patient perception of voice and speech after treatment[ncbi.nlm.nih.gov]
  • Laryngeal edema was prospectively scored after treatment. Time to endpoint, moderate or worse laryngeal edema (Radiation Therapy Oncology Group Grade 2 ), was calculated with log rank test from the date of treatment end.[ncbi.nlm.nih.gov]
  • Post-radiotherapy laryngeal edema may affect the patients' quality of life, leading to repeated treatment attempts, which include massage/physical therapy, inhalations, and/or tracheostomy.[ncbi.nlm.nih.gov]
  • She was diagnosed with COPD 2 months prior to her presentation and started on treatment with fluticasone propionate and albuterol.[ncbi.nlm.nih.gov]

Prognosis

  • Treatment and prognosis The key goals of management are: maintaining airway: preserve life restoring function to larynx: voice quality uncooperative or unstable patients may not be in the normal anatomical position on the CT scanner.[radiopaedia.org]
  • Approximately 50% of all HAE patients experience at least 1 laryngeal attack, and some patients have them repeatedly. 2 Prior to effective HAE treatments, mortality rates were approximately 30%. 8 Current treatments have helped improve the prognosis for[allabouthae.com]
  • Complications and prognosis The main risk is death from laryngeal obstruction: Laryngeal oedema has a high mortality if untreated.[patient.info]

Etiology

  • Abstract Diffuse idiopathic skeletal hyperostosis (DISH), or ankylosing hyperostosis ("Forestier's disease"), is an ossifying diathesis of unknown etiology.[ncbi.nlm.nih.gov]
  • She also had a history of recurrent laryngeal edema of unclear etiology. She had no history of IV drug abuse, no exposure to animals, was not sexually active, and had no recent travel outside of Florida.[ncbi.nlm.nih.gov]
  • Nasal polyps are sac-like growths of inflamed tissue lining the nose etiology: etiology Nasal polyps typically start near the ethmoid sinuses and grow into the open areas. Large polyps can block the sinuses or nasal airway.[authorstream.com]
  • Annals of Pharmacotherapy 2008; 42(5): 686-691 Indexing Status Subject indexing assigned by NLM MeSH Adrenal Cortex Hormones /administration & Adult; Humans; Intubation, Intratracheal /adverse effects; Laryngeal Edema /etiology /prevention & Laryngoscopy[crd.york.ac.uk]
  • Independent effects of etiology of failure and time to reintubation on outcome for patients failing extubation. Am J Respir Crit Care Med. 1998;158:489-93. [PubMed ID: 9700126 ][acpjc.acponline.org]

Epidemiology

  • […] of HAE Reliable data on the epidemiology for HAE are lacking.[worldallergy.org]
  • Epidemiology The incidence is approximately 1 in 50,000 although there may be variation geographically [ 1 ]. It can affect people of any ethnic group or gender.[patient.info]
  • […] descriptions of the condition. [26] [27] [28] William Osler remarked in 1888 that some cases may have a hereditary basis; he coined the term "hereditary angio-neurotic edema". [29] The link with C1 esterase inhibitor deficiency was proved in 1963. [30] Epidemiology[en.wikipedia.org]
Sex distribution
Age distribution

Pathophysiology

  • References Enkhbaatar P,Traber DL (2004) Pathophysiology of acute lung injury in combined burn and smoke inhalation injury. Clin Sci (Lond) 107: 137-143.[omicsgroup.org]
  • Hoover, T., et al., Angiotensin converting enzyme inhibitor induced angio-oedema: a review of the pathophysiology and risk factors. Clin Exp Allergy, 2010. 40 (1): p. 50-61. 49.[worldallergy.org]
  • A review of the literature and pathophysiology". Annals of Internal Medicine . 117 (3): 234–42. doi : 10.7326/0003-4819-117-3-234 . PMID 1616218 . Kostis JB, Kim HJ, Rusnak J, Casale T, Kaplan A, Corren J, Levy E (July 25, 2005).[en.wikipedia.org]
  • Bradykinin can mimic all the significant pathophysiological effects of histamine but is far more potent and, again, this sequence of events would not be blocked by antihistaminic drugs.[appliedradiology.com]

Prevention

  • OBJECTIVE: To evaluate the efficacy and safety of prophylactic corticosteroid therapy in preventing postextubation laryngeal edema (PELE) and the need for reintubation in adults.[ncbi.nlm.nih.gov]
  • Abstract Because laryngeal edema (LE) after tracheal extubation is likely to result from an exudative response, corticosteroids often are given routinely as a preventive treatment. No adequate controlled study supports this strategy, however.[ncbi.nlm.nih.gov]
  • If applied in a timely manner, intravenous or nebulized corticosteroids can prevent postextubation laryngeal edema; however, the inability to identify high-risk patients prevents the targeted pretreatment of these patients.[ncbi.nlm.nih.gov]
  • A possible mechanism by which this complication was produced is discussed and experience with a drug regimen to prevent its occurrence is presented.[ncbi.nlm.nih.gov]
  • When mumps is diagnosed with significant swelling of the neck, an emergency airway should be established to prevent airway obstruction.[ncbi.nlm.nih.gov]

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