Presentation
In the first case, the patient presented with vesicular eruptions in the larynx and paralysis of the glossopharyngeal, vagus, and accessory nerves on the left side. [keio.pure.elsevier.com]
About 70% of supraglottic tumours present with advanced disease (stages III-IV),1 while 75% of glottic tumours present with localized disease (stages I-II).1 Smoking and alcohol consumption are considered highly significant etiologic factors but evidence [pjohns.pso-hns.org]
A rationalisation of the 1350 boxes used throughout the book gives a simpler and clearer presentation of the various categories. [books.google.com]
About 70% of supraglottic tumours present with advanced disease (stages III-IV), 1 while 75% of glottic tumours present with localized disease (stages I-II). 1 Smoking and alcohol consumption are considered highly significant etiologic factors but evidence [philjol.info]
Herpes may prove to be a common cause of cord palsies presently labelled as idiopathic and serological tests for herpes should be asked for. [ncbi.nlm.nih.gov]
Entire Body System
- Candidiasis
Oral candidiasis as a marker for esophageal candidiasis in the acquired immunodeficiency syndrome. Ann Intern Med 1986;104:54-55. 89. Marelli RA, Biddinger PW, Gluckman JL. [hivinsite.ucsf.edu]
Fungal Infection: Candidiasis. Immunosuppression and the use of steroid inhalers are risk factors. Trauma: Trauma due to voice misuse - screaming, yelling, loud singing. [patient.info]
Granulomatous fungal infections can also affect the larynx, including candidiasis ( Candida albicans ), blastomycosis ( Blastomycosis dermatitidis ), histoplasmosis ( Histoplasma capsulatum ) ( Figure 7 ), aspergillosis ( Aspergillus fumigatus ), coccidioidomycosis [nature.com]
- Pallor
Other warning signs of severe respiratory disease are tachypnea, tachycardia out of proportion to the presence of fever, lethargy, pallor, and hypotonia (decreased muscle tone). [atsu.edu]
Respiratoric
- Hoarseness
Hoarseness is a harsh, rough, raspy quality to the voice. Hoarseness is generally caused by irritation of, or injury to, the vocal cords. This trauma to the vocal cords leads to a change in the pitch of the voice. [medicinenet.com]
Luke’s Medical Center, Quezon City DOI: https://doi.org/10.32412/pjohns.v31i1.325 Keywords: Viruses, Carcinoma Abstract Laryngeal SCCA usually presents with hoarseness when the glottis is involved, dysphagia if the supraglottis is involved, and difficulty [pjohns.pso-hns.org]
Laryngeal SCCA usually presents with hoarseness when the glottis is involved, dysphagia if the supraglottis is involved, and difficulty of breathing and stridor in subglottic invovlement. [philjol.info]
After 15 months, he had mild facial palsy and hoarseness, but no hearing loss, dizziness, dysphagia, or hiccups. [e-jnc.org]
We present a 62-year-old woman presented with neck pain, hoarseness, crepitus over the larynx, and what appeared to be a necrotic mass of the right true vocal cord on laryngoscopy. [ncbi.nlm.nih.gov]
- Stridor
Once stridor develops, you may only have minutes to act. [atsu.edu]
Mass Psychogenic Illness Presenting as Acute Stridor in an Adolescent Female Cohort. Annals of Otology, Rhinology & Laryngology, Vol. 116, Issue. 7, p. 525. CrossRef Google Scholar Miner, Lonnie and Bale, James F. 2006. [cambridge.org]
Our patient was observed to have dysphagia and stridor, but evaluation of dysphonia was difficult due to the tracheostomy. [ncbi.nlm.nih.gov]
We report a case of a 69-year-old woman, smoker, who presented with a large ulcerated supraglottic mass mimicking laryngeal cancer, requiring emergency tracheostomy for worsening stridor, which turned out to be an HSV laryngitis superimposed onto an underlying [casereports.bmj.com]
- Pneumonia
In the absence of bacterial pneumonia, recovery generally occurs 4-5 days after the onset of signs. IBR. [veepro.nl]
The second case study refers to a patient with severe kyphoscoliosis who was intubated for acute on chronic hypercapnic respiratory failure due to community-acquired pneumonia. [mrmjournal.biomedcentral.com]
Cats with feline calicivirus infection do not sneeze as often and have less eye discharge and inflammation; they are also more likely to have pneumonia. [healthcommunities.com]
Streptococcus pneumoniae. Staphylococcus aureus. Group B beta-haemolytic streptococci. Moraxella catarrhalis. Klebsiella pneumoniae. Less commonly in the developed world, mycobacterial and syphilitic infection. Fungal Infection: Candidiasis. [patient.info]
Other Causes of Epiglottitis Bacteria Streptococcus groups A, B, and C, Nontypeable Haemophilus influenzae, Streptococcus pneumoniae, Klebsiella pneumoniae, Staphylococcus aureus, Haemophilus parainfluenza, Neisseria meningitidis Viruses Varicella zoster [atsu.edu]
- Dyspnea
[…] severe headache; shows signs of poor balance or has trouble walking; finds bright lights hard to look at; is having breathing problems or is coughing a lot; In severe cases, laryngeal or tracheal vesicles in the pharynx, larynx, and trachea may cause dyspnea [lianavargas.com]
Erosive lesions may lead to scarring, stenosis, synechiae, obstruction, and dyspnea. Q: What is oral pemphigus vulgaris? A: Pemphigus vulgaris is an intraepithelial blistering disorder. [blogs.nejm.org]
Clinical signs include high fever, anorexia, coughing, excessive salivation, nasal discharge that progresses from serous to mucopurulent, conjunctivitis with lacrimal discharge, inflamed nares (hence the common name ‘red nose’), and dyspnea if the larynx [veepro.nl]
On the day of examination he was not found with dyspnea. His GP agreed to stop the Beclomethasone and put him on a Salbutamol inhaler. [edoj.org.eg]
[…] among the edema is edema of the epiglottis (the lid larynx), which makes it difficult to swallow and that, in most cases, makes it difficult to breathe, other edema can affect vocal cords, especially their bottom surface, causing a delay in breathing or dyspnea [laryngitisknowledgebase.com]
- Respiratory Distress
He responded well to acyclovir therapy, did not develop respiratory distress, was conservative, and became asymptomatic within 2 weeks. [laryngologyandvoice.org]
Pyrexia, ocular and nasal discharges, respiratory distress, diarrhea, incoordination, and eventually convulsions and death may occur in a short period after generalized viral infection Diagnosis Uncomplicated BHV-1 infections can be diagnosed based on [veepro.nl]
Steroid is often recommended along with antiviral therapy for minimizing the laryngeal edema in acute respiratory distress.[6] Steroids help to reduce the inflammation of the cranial nerves and alleviate the neurological symptoms and pain. [jscisociety.com]
distress syndrome, failure to thrive, and recurrent upper respiratory infections can be diagnosed. [4] [5] The risk of laryngeal papillomatosis spreading to the lungs is higher in the juvenile-onset than the adult-onset. [3] In children, symptoms are [en.wikipedia.org]
Gastrointestinal
- Constipation
Constipation is also a common side effect caused by change of diet and medications. Some patients experience odynophagia (pain on swallowing) and others experience total dysphagia. Enteral feeding is common for head and neck cancer patients. [inmo.ie]
Jaw & Teeth
- Oral Ulcers
There was no fever, cough, nasal discharge or congestion, hoarseness, dysphagia, difficulty of breathing, weight loss, oral ulcers, difficulty opening and closing the mouth, or facial asymmetry, and he did not consult a health professional or take any [pjohns.pso-hns.org]
- Halitosis
Dyspnoea and stridor, pain, dysphagia, cough, swelling in the neck, haemoptysis, halitosis, reflective otalgia, tenderness of the larynx and weight loss can also occur during the course of disease. [atlasgeneticsoncology.org]
- Aphthous Ulceration
aphthous lesions, HIV-infected patients frequently present with giant (several centimeters in diameter) aphthous ulcerations. [hivinsite.ucsf.edu]
Skin
- Skin Lesion
For patients with skin lesions associated with varicella or smallpox or draining skin lesions caused by M. tuberculosis, cover the affected areas to prevent aerosolization or contact with the infectious agent in skin lesions IB V.D.5.d. [cdc.gov]
Both the skin lesions and hiccups responded promptly to acyclovir therapy further strengthening this correlation. Acknowledgement We thank Dr. Kura Sharath Chandra, MD, MPH (New Jersey, USA) and Dr. H. [ijdvl.com]
Lesions begin in the oral cavity in up to 60% of patients, with skin lesions developing months or years later. The soft palate and the mucosa of the hard palate are commonly involved because of trauma from swallowing. [blogs.nejm.org]
A distinctive feature of varicella is the simultaneous presence, in any one area of the skin, of lesions in all stages of development. [plasticsurgerykey.com]
Although skin lesions can occur on the nose and face, sinus and intranasal lesions are less common. [hivinsite.ucsf.edu]
- Dermatitis
Seborrheic Dermatitis Facial seborrheic dermatitis also occurs in HIV-infected patients. [hivinsite.ucsf.edu]
Scabies Always Rule Out Secondary syphilis Disseminated herpes zoster Dermatitis herpetiformis Smallpox and other poxviruses Always Rule Out Bullous pemphigoid Pemphigus vulgaris Dermatitis herpetiformis Epidermolysis bullosa herpetiformis Clinical Diagnosis [plasticsurgerykey.com]
Neurologic
- Irritability
CONCLUSION: Neuronal damage by varicella-zoster virus results in irritable nociceptors and deafferentation, mechanisms known to cause post-herpetic neuralgia. [ncbi.nlm.nih.gov]
Hoarseness is generally caused by irritation of, or injury to, the vocal cords. This trauma to the vocal cords leads to a change in the pitch of the voice. [medicinenet.com]
The symptoms of laryngitis include hoarse voice, sore throat, difficult speaking, headache, mild fever, irritating cough. You may only able to whisper, or you may not be able to talk at all. [laryngitisknowledgebase.com]
Overview MeSH Major Cough Herpes Zoster Laryngeal Diseases abstract Neuronal damage by varicella-zoster virus results in irritable nociceptors and deafferentation, mechanisms known to cause post-herpetic neuralgia. [vivo.med.cornell.edu]
Prevention There are no particular preventative measures for acute laryngitis, although avoidance of irritant factors such as cigarette smoke may be helpful. [patient.info]
Workup
Previous workup of these episodes included a negative electroencephalogram and CT scan and negative cerebrospinal fluid, serologic, and skin tests for relevant microbial pathogens. [nejm.org]
Serum
- Neutropenia
Other potentially serious adverse effects with parenteral cidofovir include: neutropenia (reduced neutrophil white cells) nephrotoxicity ocular effects metabolic acidosis Use of cidofovir in special populations Pregnancy and lactation No studies regarding [dermnetnz.org]
Microbiology
- Candida
These include dry mouth and throat, hoarseness voice and oropharangeal and laryngeal infection with candida.[ 1 ] The present article describes the occurrence of herpes simplex of the buccal mucosa in a steroid - dependent immunocompetent asthmatic child [edoj.org.eg]
Immunosuppressant therapy - consider candida. Inhalation treatments - thermal baths. Surgical history: History of intubation - recurrent laryngeal damage, particularly likely in thoracic and abdominal surgery. [patient.info]
Epiglottitis Bacteria Streptococcus groups A, B, and C, Nontypeable Haemophilus influenzae, Streptococcus pneumoniae, Klebsiella pneumoniae, Staphylococcus aureus, Haemophilus parainfluenza, Neisseria meningitidis Viruses Varicella zoster virus Fungi Candida [atsu.edu]
Pneumocystis carinii, M. tuberculosis, and Candida have been cultured from the middle ear aspirates of HIV-infected patients. [hivinsite.ucsf.edu]
Granulomatous fungal infections can also affect the larynx, including candidiasis ( Candida albicans ), blastomycosis ( Blastomycosis dermatitidis ), histoplasmosis ( Histoplasma capsulatum ) ( Figure 7 ), aspergillosis ( Aspergillus fumigatus ), coccidioidomycosis [nature.com]
Laboratory
- Leukocytosis
A leukocytosis can be seen in the complete blood count (CBC). A positive thumb sign on lateral radiographs of the neck is diagnostic of epiglottitis. [atsu.edu]
Treatment
A problem-based approach makes it easy to apply principles to treatment planning and delivery. New to this edition are updates on current equipment, procedures, and treatment planning. [books.google.de]
In this case also, the paralysis of the acoustic and vagus nerves persisted after the treatment. [keio.pure.elsevier.com]
Chemotherapy is also occasionally used for palliative treatment in advanced head and neck cancers. Management post treatment Side effects of head and neck cancer treatment do not generally heal for at least one month on completion of treatment. [inmo.ie]
Prognosis
Further, half of the cases reported in the literature did not present with any vesicular eruptions, and delay in treatment worsened the neurological prognosis. [keio.pure.elsevier.com]
Rarely, in severe infections such as those with herpes viruses, laryngeal erosion and necrosis may occur. [ 1 ] Prognosis In acute laryngitis, the prognosis is usually excellent. [patient.info]
Generally, the prognosis for facial nerve palsy caused by VZV reactivation is poorer than that of Bell’s palsy [10]. [hindawi.com]
Prognosis of ramsay hunt syndrome presenting as cranial polyneuropathy. Laryngoscope. 2010;120:2270-6. Patro S, Mishra GC, Toppo L, Katua P. Ramsay hunt syndrome with 8th cranial nerve palsy in a diabetic patient. [ijmedicine.com]
Etiology
The difficulties involved in diagnosing HSV CNS disease before death are discussed, and the medical literature is reviewed for evidence that HSV is the etiological agent in selected cranial neuropathies. (Arch Intern Med 139:1423-1424, 1979) [jamanetwork.com]
Viral carcinogenesis: revelation of molecular mechanisms and etiology of human disease. Carcinogenesis, 21 (2000), pp. 405-426 [4.] Z. Hausen. [elsevier.es]
This made it more difficult to diagnose, since neck masses can have varying etiologies involving a large number of different structures of the head and neck. [pjohns.pso-hns.org]
Many different risk factors play a role in the etiology of oral cancer. [ar.iiarjournals.org]
Epidemiology
Decannulation 252 Recurrent Respiratory Papillomatosis 255 Historical Perspective 256 Epidemiology 258 Disease Progression and Complications 259 Managing RRP in Children 260 AnesthesiaAirway Management Techniques 261 Adjuvant Medical Therapy 262 Photodynamic [books.google.de]
Epidemiology Epidemiology of Varicella Varicella is distributed worldwide, but its age-specific incidence differs in temperate versus tropical climates, and in populations that have received varicella vaccine. [plasticsurgerykey.com]
DISCUSSION This study establishes an epidemiological link between HSV and laryngeal cancer. However, this virus cannot be implicated in carcinogenesis until the mechanism of action is elucidated, that is, until causality is established. [onlinelibrary.wiley.com]
It can be used for molecular epidemiology, diagnostics and targeting. [atlasgeneticsoncology.org]
Epidemiology of human papillomavirus detected in the oral cavity and fingernails of mid-adult women. Sex. Transm. Dis. 42(12), 677–685 (2015).Crossref, Medline, Google Scholar 13. Taghavi-Farahabadi M, Mahmoudi M, Rezaei N, Hashemi SM. [futuremedicine.com]
Pathophysiology
We present one case of herpetic laryngitis by reactivation of varicella zoster, with central nervous system spreading, and discuss the relevant literature on the pathophysiology, diagnosis, evaluation, and management of this disease. [ncbi.nlm.nih.gov]
RRP in Children 260 AnesthesiaAirway Management Techniques 261 Adjuvant Medical Therapy 262 Photodynamic Therapy 263 Pharynx and Oesophagus 266 Ontogeny of Oesophageal Motor Function 269 The Oesophageal Phase 270 Oesophageal Sphincter Physiology 271 Pathophysiology [books.google.de]
This suggests that differences in pathophysiology between LPR and GERD patients are part of the basis for the contrasting symptomology. [nature.com]
Prevention
Cancer Prevention and Smoking Tobacco use, particularly smoking, is the single most preventable cause of death in the United States. [my.clevelandclinic.org]
Of the cancers that are linked to herpes, cervical cancer stands out as one that could be prevented. It's important to find and treat pre-cancers before they become malignant, and then to prevent the pre-cancers. [qualityhealth.com]
Early administration (< 72 h) of acyclovir showed an increased rate of facial nerve function recovery and prevented further nerve degeneration. [emedicine.medscape.com]
US Preventive Services Task Force. Screening for bacterial vaginosis in pregnancy to prevent preterm delivery: U.S. Preventive Services Task Force recommendation statement. Ann Intern Med. 2008;148:214–9. 22. [cdc.gov]