In this report, a late onset depression was the initial presentation of SREAT in a middle aged patient, something rarely described before, indicating the need to suspect SREAT as a possible etiology for depression in this age group. [ncbi.nlm.nih.gov]

• Pulmonary Disorder

  disorder; interleukin 10; late onset depression; polymerase chain reaction; single nucleotide polymorphism [ncbi.nlm.nih.gov]

• Motor Symptoms

  PURPOSE: Lewy body disease (LBD) is comprised of a spectrum of diseases that includes Parkinson's disease (PD), PD dementia (PDD) and dementia with LBD (DLBD), an array of dementia, and motor symptoms. [ncbi.nlm.nih.gov]

  The frequency and severity of each NMS was evaluated by Non-Motor Symptom Scale (NMSS), which consists of 9 subdomains. [pubfacts.com]

  She had a long history of epilepsy and headache, epilepsy consisting of both partial and generalized seizures, simple partial seizures presenting with motor symptoms and causing jerking movements of the foot, face, arm and complex partial seizures showing [dovepress.com]

• Akinesia

  When both groups were matched for duration of the disease, the early-onset group still showed a significantly higher frequency of depression, whereas tremor, akinesia, and rigidity were significantly more severe in the late-onset group. [neurology.org]

  Changes are characterized by indifference, apathy, reduced sexuality, akinesia, loss of initiative and crying. [dovepress.com]

Physical examination to rule out any medical or neurological disorder should be part of the total workup. [statpearls.com]

• White Matter Lesions

  Therefore, we wished to investigate the relationship between age of first depression onset and hippocampal volume, with adjustment for subcortical white matter lesions. [ncbi.nlm.nih.gov]

  Some white matter lesions may be vascular in origin. [research.manchester.ac.uk]

• Gliosis

  Neuropathological evaluation included bilateral semi-quantitative assessment of lacunes, deep white matter and periventricular demyelination, cortical microinfarcts and both focal and diffuse gliosis. [ncbi.nlm.nih.gov]

Multivariate analysis showed that treatment with tricyclic or tetracyclic antidepressants, atypical antipsychotics were associated with prolonged LOHS. [ncbi.nlm.nih.gov]

Further research is warranted to ascertain the link between late-onset depression, neuropsychological deficits and prognosis. Copyright 2010 John Wiley & Sons, Ltd. [ncbi.nlm.nih.gov]

This will give us a better understanding of the connection between brain changes, neuropsychology and depression prognosis, which is decisive for accurate diagnostics, effective treatment and targeted prevention of the disease in the long run. [clinicaltrials.gov]

In fact for every medical illness studied, e.g. heart disease, diabetes, cancer, individuals who are depressed have a worse prognosis. [books.google.com]

Millard proposed the 'rule of thirds' concerning the prognosis of geriatric depression [ 114 ]. [annals-general-psychiatry.biomedcentral.com]

In this report, a late onset depression was the initial presentation of SREAT in a middle aged patient, something rarely described before, indicating the need to suspect SREAT as a possible etiology for depression in this age group. [ncbi.nlm.nih.gov]

Various theories have been postulated to elucidate the etiology of late onset depression, but a unifying hypothesis is lacking. [go.gale.com]

These data suggest that depression in patients with early-onset PD may have a different etiology than in patients with late-onset PD. 1989 by the American Academy of Neurology AAN Members: Sign in with your AAN member credentials (e-mail or 6-digit Member [neurology.org]

Emerging data suggest that late-onset depression is a distinct entity with a pathophysiology, etiology, trajectory and treatment response different from adult MDD. [isctm.org]

OBJECTIVES: In this paper we review clinical, epidemiological, structural neuroimaging and genetic investigations of late life depression that have been performed over the past two decades and offer evidence that LOD is often a prodromal disorder for [ncbi.nlm.nih.gov]

[sup][2] The prevalence of either a major depressive episode or dysthymia in the epidemiologic catchment area survey was 2.5% in the geriatric age group. [go.gale.com]

This is the first volume devoted to the epidemiology, phenomenology, psychobiology, treatment and consequences of late-life depression. [books.google.com]

Patients who scored 16 on the Center for Epidemiologic Studies Depression Scale (CES-D) and/or were currently taking antidepressant medication specifically for the treatment of depression were considered to have depressive symptoms. [psychiatryadvisor.com]

CONCLUSIONS: Our findings suggest that loss of white matter integrity in parahippocampal gyrus may be associated with the pathophysiology of LOD, and thus highlight the limbic contribution to the pathophysiology of LOD. Copyright 2014 Elsevier B.V. [ncbi.nlm.nih.gov]

These differential findings are important factors to keep in mind for diagnostics, treatment, and prevention. Copyright 2012 Elsevier B.V. All rights reserved. [ncbi.nlm.nih.gov]