Their presentation may be masked by the use of antibiotics. We present a unique case of acute otitis media progressing to occipital, extradural and subdural abscess formation and lateral sinus thrombosis in a child. [ncbi.nlm.nih.gov]

• Pediatric Disease

  METHODS: A retrospective review was conducted of the clinical records of patients with OLST, treated in a single tertiary care referral center for pediatric disease from 2006 to 2017. [ncbi.nlm.nih.gov]

• Lymphadenopathy

  As the clot proliferates along the sinus, it is accompanied by peri-venous inflammation, tenderness, and jugular lymphadenopathy. The increased intracranial pressure is usually suggested by papilledema and visual loss. [sjmms.net]

• Swinging Fever

  The third group comprises all causes of inflammation, infection, or damage to the sinus wall. [18] The classic presentation of cerebral venous sinus thrombosis is severe illness associated with typically high and swinging fever. [sjmms.net]

• Aspiration

  Because pus was not aspirated via punctures of the other two cases, their sinuses were not explored. Only radical mastoidectomy was performed surgically for these cases. [ncbi.nlm.nih.gov]

• Vesicular Rash

  Zoster sine herpete (ZSH) is an uncommon manifestation of VZV infection and presents with similar symptoms but without the vesicular rash. [ncbi.nlm.nih.gov]

• Postauricular Pain

  A 55-year-old woman presented with a 3-day history of left temporal and postauricular pain, nausea, vomiting, and mild photophobia. She denied otalgia, otorrhea, and hearing loss. [ncbi.nlm.nih.gov]

• Dysphasia

  Dysphasia was the most common one (8 patients). [ncbi.nlm.nih.gov]

  The main focal sign was dysphasia due to a left temporal ischemic or hemorrhagic lesion secondary to thrombosis of the vein of Labbé, which drains in LS. Its frequency (13%) was the same as in other CVT. [stroke.ahajournals.org]

All children underwent laboratory workup for hypercoagulability. All the five children were found to be heterozygote for the C677T MTHFR mutation and a child presented also heterozygosity for factor V Leiden mutation. [ncbi.nlm.nih.gov]

Diagnosis Orbital cellulitis Internal carotid artery aneurysm Stroke Migraine headache Allergic blepharitis Thyroid exophthalmos Brain tumor Meningitis Mucormycosis Trauma Workup[edit] Cavernous sinus thrombosis is a clinical diagnosis with laboratory [pediascape.org]

Symptoms and signs, presence or absence of papilledema, modes of onset, neuroimaging findings, causes and risk factors, including a thrombophilic workup, and outcome at discharge and at 1 year were systematically recorded. [stroke.ahajournals.org]

Intracranial complications in children resulted from unsuccessful treatment of AOM, which led to acute mastoiditis and lateral sinus thrombosis. [ncbi.nlm.nih.gov]

The prognosis of LST is good if treatment is instituted early with broad-spectrum intravenous antibiotics and surgery. The role of clot removal at surgery and the use of anticoagulation are discussed in this paper. [ncbi.nlm.nih.gov]

Prognosis of cerebral vein and dural sinus thrombosis: Results of the International Study on Cerebral Vein and Dural Sinus Thrombosis (ISCVT). Stroke 2004;35:664-70. 2. Tanislav C, Siekmann R, Sieweke N, Allendörfer J, Pabst W, Kaps M, et al. [joacp.org]

The overall prognosis was good with 85% of patients having an mRS of 0 or 1 at discharge. This was significantly better than for the other varieties of CVT. [stroke.ahajournals.org]

Clinical, etiologic, and prognostic features were compared with those of other 133 CVT cases. RESULT: Sixty-two patients (32%) had isolated lateral sinus thrombosis. Headaches were present in 95% of patients. [ncbi.nlm.nih.gov]

Etiologic investigation lead to the diagnosis of left lateral sinus thrombosis. Anticoagulation was started with heparin followed by dicumarinics. This treatment was maintained during eight months. [actamedicaportuguesa.com]

In 183 short chapters, the book provides the essentials clinicians need on symptoms/signs, diagnostic tests, and neurologic disorders of all etiologies. For this edition, Timothy A. [books.google.com]

Synonyms Thrombosis of lateral venous sinus (disorder) ; Thrombosis transverse sinus (disorder) ; Etiology Please input defination information here. [pediascape.org]

Source: Current Opinion in Rheumatology - January 29, 2019 Category: Rheumatology Tags: EPIDEMIOLOGY AND HEALTH-RELATED SERVICES: Edited by Kenneth Saag Source Type: research Conclusion: Patients who sustain an unstable pelvic fracture continue to have [medworm.com]

Epidemiology Frequency Lateral sinus thrombosis accounts for 6% of all intracranial complications in the era of antibiotic treatment of suppurative ear disease. [emedicine.medscape.com]

Please refer to the article on cerebral venous thrombosis for a broad discussion on epidemiology and risk factors. Presentation is variable and can range from asymptomatic to coma and death. [radiopaedia.org]

Epidemiology Intracranial venous thrombosis appears to have become more common in recent years. However, this has occurred as modern imaging techniques have improved diagnosis. [patient.info]

To describe a case of lateral sinus insufficiency, presumably occurring just prior to lateral sinus thrombosis (LST), and to discuss the importance of early surgical intervention and the pathophysiology of full-blown LST. [ncbi.nlm.nih.gov]

Further inflammation of outer and inner walls of sinus results in the formation of mural thrombosis. [3] In our case, the pathophysiology was osteothrombophlebitis of small venules as evident from radiology of temporal bone (HRCT temporal bone). [indianjotol.org]

In: Barnett HJM, Mohr JP, Stein BM, Yatsu FM (eds) Stroke: pathophysiology, diagnosis and management, 3rd edn. Churchill Livingstone, New York, NY, pp 623–647 Google Scholar 7. [link.springer.com]

Schaller B, Graf R: Cerebral ischemia and reperfusion: the pathophysiologic concept as a basis for clinical therapy. J Cereb Blood Flow Metab 2004;24:351–371. [karger.com]

Pathophysiology • Perisinus abscess  penetrates dura  reaches intima  mural thrombus forms due to intimal damage, hypercoagulation and blood flow in sinus • Bacteria & thrombus  platelet aggregtion  fibrin formation  mural clot  necrosis of clot [slideshare.net]

Anticoagulants have been advocated to prevent extension of the thrombus to the distal sinuses. [emedicine.medscape.com]

A case of lateral sinus insufficiency with acute otitis media: Early surgical intervention for prevention of lateral sinus thrombosis. Auris Nasus Larynx, Vol. 42, Issue. 6, p. 492. CrossRef Google Scholar Singh, Gautam Bir Rai, Anil K. [cambridge.org]

Recently, anti-coagulant treatment has been proposed to prevent complications associated with thrombus persistence or its possible propagation 11. [ncbi.nlm.nih.gov]

Anticoagulation has been advocated to prevent extension of the thrombus to distal sinuses(27,28). However, it is rarely used now as most infections can be controlled with antibiotics and surgery, and this tends to prevent thrombus propagating. [arquivosdeorl.org.br]

This prevents blood from draining out of the brain. As a result, blood cells may break and leak blood into the brain tissues, forming a hemorrhage. This chain of events is part of a stroke that can occur in adults and children. [hopkinsmedicine.org]