Presentation
The Late presenting group experienced acute otitis media several weeks prior to presentation and in this group neurologic symptoms dominated the clinical picture at admission. All patients received antibiotics. [ncbi.nlm.nih.gov]
Entire Body System
- Swinging Fever
The third group comprises all causes of inflammation, infection, or damage to the sinus wall. [18] The classic presentation of cerebral venous sinus thrombosis is severe illness associated with typically high and swinging fever. [sjmms.net]
Respiratoric
- Aspiration
Because pus was not aspirated via punctures of the other two cases, their sinuses were not explored. Only radical mastoidectomy was performed surgically for these cases. [ncbi.nlm.nih.gov]
Skin
- Vesicular Rash
Zoster sine herpete (ZSH) is an uncommon manifestation of VZV infection and presents with similar symptoms but without the vesicular rash. [ncbi.nlm.nih.gov]
Ears
- Ear Discharge
They presented with low-grade fever, headache, nausea, vomiting and ear discharge. One patient had facial nerve palsy. CT scan was helpful in managing these patients. They were treated with antibiotics followed by surgery. [ncbi.nlm.nih.gov]
Examination showed slight discharge with an inflamed right ear drum and no neurological signs apart from neck stiffness. A CT scan revealed right transverse sinus thrombosis. He was treated with intravenous antibiotics and heparin. [123doc.com]
A haemogram, a routine urine study and the culture and sensitivity (c/s) of the ear discharge was done in all the cases. [jcdr.net]
- Postauricular Pain
A 55-year-old woman presented with a 3-day history of left temporal and postauricular pain, nausea, vomiting, and mild photophobia. She denied otalgia, otorrhea, and hearing loss. [ncbi.nlm.nih.gov]
Workup
All children underwent laboratory workup for hypercoagulability. All the five children were found to be heterozygote for the C677T MTHFR mutation and a child presented also heterozygosity for factor V Leiden mutation. [ncbi.nlm.nih.gov]
Diagnosis ~Orbital cellulitis~Internal carotid artery aneurysm~Stroke~Migraine headache~Allergic blepharitis~Thyroid exophthalmos~Brain tumor~Meningitis~Mucormycosis~Trauma~Workup[edit]~Cavernous sinus thrombosis is a clinical diagnosis with laboratory [pediascape.org]
Symptoms and signs, presence or absence of papilledema, modes of onset, neuroimaging findings, causes and risk factors, including a thrombophilic workup, and outcome at discharge and at 1 year were systematically recorded. [stroke.ahajournals.org]
Treatment
Intracranial complications in children resulted from unsuccessful treatment of AOM, which led to acute mastoiditis and lateral sinus thrombosis. [ncbi.nlm.nih.gov]
Prognosis
The prognosis of LST is good if treatment is instituted early with broad-spectrum intravenous antibiotics and surgery. The role of clot removal at surgery and the use of anticoagulation are discussed in this paper. [ncbi.nlm.nih.gov]
Prognosis of cerebral vein and dural sinus thrombosis: Results of the International Study on Cerebral Vein and Dural Sinus Thrombosis (ISCVT). Stroke 2004;35:664-70. 2. Tanislav C, Siekmann R, Sieweke N, Allendörfer J, Pabst W, Kaps M, et al. [joacp.org]
Complications include seizures, hydrocephalus, intracranial hypertension and neurological deterioration. [ 10 ] Prognosis Long-term follow-up suggests a generally good prognosis but there may be residual pyramidal symptoms, epilepsy, visual field defects [patient.info]
Etiology
Etiologic investigation lead to the diagnosis of left lateral sinus thrombosis. Anticoagulation was started with heparin followed by dicumarinics. This treatment was maintained during eight months. [actamedicaportuguesa.com]
Clinical, etiologic, and prognostic features were compared with those of other 133 CVT cases. RESULT: Sixty-two patients (32%) had isolated lateral sinus thrombosis. Headaches were present in 95% of patients. [ncbi.nlm.nih.gov]
In 183 short chapters, the book provides the essentials clinicians need on symptoms/signs, diagnostic tests, and neurologic disorders of all etiologies. For this edition, Timothy A. [books.google.com]
Etiology :1. Associated lateral sinus thrombosis obstruction of cerebral venous return. 2. Superior sagittal sinus thrombosis ed C.S.F. absorption Both of these factors result in raised ICP 16. Clinical features • Symptoms 1. [slideshare.net]
Epidemiology
Source: Current Opinion in Rheumatology - January 29, 2019 Category: Rheumatology Tags: EPIDEMIOLOGY AND HEALTH-RELATED SERVICES: Edited by Kenneth Saag Source Type: research Conclusion: Patients who sustain an unstable pelvic fracture continue to have [medworm.com]
Epidemiology Frequency Lateral sinus thrombosis accounts for 6% of all intracranial complications in the era of antibiotic treatment of suppurative ear disease. [emedicine.medscape.com]
Please refer to the article on cerebral venous thrombosis for a broad discussion on epidemiology and risk factors. Presentation is variable and can range from asymptomatic to coma and death. [radiopaedia.org]
Epidemiology Intracranial venous thrombosis appears to have become more common in recent years. However, this has occurred as modern imaging techniques have improved diagnosis. [patient.info]
Pathophysiology
To describe a case of lateral sinus insufficiency, presumably occurring just prior to lateral sinus thrombosis (LST), and to discuss the importance of early surgical intervention and the pathophysiology of full-blown LST. [ncbi.nlm.nih.gov]
Further inflammation of outer and inner walls of sinus results in the formation of mural thrombosis. [3] In our case, the pathophysiology was osteothrombophlebitis of small venules as evident from radiology of temporal bone (HRCT temporal bone). [indianjotol.org]
In: Barnett HJM, Mohr JP, Stein BM, Yatsu FM (eds) Stroke: pathophysiology, diagnosis and management, 3rd edn. Churchill Livingstone, New York, NY, pp 623–647 Google Scholar 7. [link.springer.com]
Pathophysiology • Perisinus abscess penetrates dura reaches intima mural thrombus forms due to intimal damage, hypercoagulation and blood flow in sinus • Bacteria & thrombus platelet aggregtion fibrin formation mural clot necrosis of clot [slideshare.net]
Schaller B, Graf R: Cerebral ischemia and reperfusion: the pathophysiologic concept as a basis for clinical therapy. J Cereb Blood Flow Metab 2004;24:351–371. [karger.com]
Prevention
Anticoagulants have been advocated to prevent extension of the thrombus to the distal sinuses. [emedicine.medscape.com]
Anticoagulation has been advocated to prevent extension of the thrombus to distal sinuses(27,28). However, it is rarely used now as most infections can be controlled with antibiotics and surgery, and this tends to prevent thrombus propagating. [arquivosdeorl.org.br]
This prevents blood from draining out of the brain. As a result, blood cells may break and leak blood into the brain tissues, forming a hemorrhage. This chain of events is part of a stroke that can occur in adults and children. [hopkinsmedicine.org]
A case of lateral sinus insufficiency with acute otitis media: Early surgical intervention for prevention of lateral sinus thrombosis. Auris Nasus Larynx, Vol. 42, Issue. 6, p. 492. CrossRef Google Scholar Singh, Gautam Bir Rai, Anil K. [cambridge.org]