Abstract Lattice degeneration has certain invariable histologic features but presents clinically in a variety of similar and dissimilar forms. [ncbi.nlm.nih.gov]

Prevalence It is present in about 8 percent of the general population and occurs in about 40 percent of eyes with retinal detachment. Symptoms The patient is nearly always asymptomatic, except for possible complaints of flashing lights. [retinahawaii.com]

The present study durther highlights the role of hereditary factors in the development of lattice degeneration of the retina. [ijo.in]

• Death in Infancy

  […] in infancy. striatonigral degeneration a form of multiple system atrophy with nerve cell degeneration mainly in the region of the substantia nigra and the neostriatum; symptoms are similar to those of parkinsonism. subacute combined degeneration of spinal [medical-dictionary.thefreedictionary.com]

• Gliosis

  […] cause subsequent retinal detachment Fundoscopy: circumferential area of involvement with small criss-crossing white lattice lines (thickened hyalinized blood vessels) Microscopic (histologic) description Atrophic and thinned retina with superficial gliosis [pathologyoutlines.com]

• Granulovacuolar Degeneration

  See Age-related macular degeneration, Ballooning degeneration, Fatty degeneration, Feathery degeneration, Granulovacuolar degeneration, Hereditary degeneration, Liquefactive degeneration, Macular degeneration, Myxoid degeneration, Paraneoplastic cerebellar [medical-dictionary.thefreedictionary.com]

In one case laser treatment was not able to cause a firm chorioretinal adhesion and RD progressed to the macula despite the treatment. In this highly myopic patient a complete PVD was present at the time of laser treatment. [bjo.bmj.com]

Treatment should be considered if the detachments are documented to increase in size.4,5 Generally, however, atrophic round holes within lattice lesions and minimal subretinal fluid do not require treatment. [ejournalofophthalmology.com]

The risk of retinal detachment in lattice degeneration with atrophic holes was estimated to be about 1 in 90 patients, and prophylactic treatment for this common anomaly is not readily recommended. [ncbi.nlm.nih.gov]

April 2011 Volume 52, Issue 14 Free ARVO Annual Meeting Abstract April 2011 Treatment Of Lattice Degeneration In Vitrectomy For Rhegmatogenous Retinal Detachment Author Affiliations & Notes Young-Joon Jo Ophthalmology, Chungnam National University, Daejeon [iovs.arvojournals.org]

Subclinical RD was seen in 10 (6.7%) of 150 eyes with atrophic holes, involving 9 (7.5%) of 120 patients, and had a much less serious prognosis than clinical detachment. [ncbi.nlm.nih.gov]

Prognosis The prognosis of lattice degeneration is generally good. Patient Education Educate the patient on signs of retinal detachment. Encourage annual follow-up for dilated eye examinations. [emedicine.medscape.com]

Prognosis The prognosis for lattice degeneration in itself is good. The vast majority of patients will have lesions that are completely stable or slowly progressive. [eyewiki.aao.org]

Diagnosis and Prognosis: Lattice degeneration of the retina also occurs in individuals who do not carry this mutation and therefore your ophthalmologist must weigh the clinical signs as well as the family history. [disorders.eyes.arizona.edu]

Prognosis No complications are encountered in most patients with lattice degeneration, although in young myopes, retinal detachment can occur. [ipfs.io]

The etiology of this degeneration is still uncertain, but it is likely that both genetic and environmental factors play important roles in its development. [ncbi.nlm.nih.gov]

P athophysiology The etiology of lattice is questionable. It appears to be due to dropout of peripheral retinal capillaries with resulting ischemia, which induces thinning of all retinal layers. [eyecaretrust.org.uk]

Lattice Degeneration Etiology Lattice degeneration is a common clinical entity which has many morphologies. [eyewiki.aao.org]

The epidemiology of lattice degeneration is summarized, as are the possible precursors to retinal detachment. A clinical characterization of the natural history of lattice degeneration is offered, and interventions for complications are described. [ncbi.nlm.nih.gov]

Epidemiology Frequency United States Lattice degeneration affects approximately 10% of the population and is bilateral in 30-50% of patients who are affected. [emedicine.medscape.com]

This discussion outlines the pathophysiology of lattice retinal degeneration and the relationship of pathophysiology to clinical presentation. [ncbi.nlm.nih.gov]

[…] disease of the peripheral retina characterized by oval or linear patches of retinal thinning. [1, 2] The prevalence peaks by the second decade and is believed to be minimally progressive but may be complicated by retinal breaks and retinal detachment. [3] Pathophysiology [emedicine.medscape.com]

[…] loss of neurons, accumulation of glial material, pigment changes, and changes to the inner limiting lamina. [2] It has also been shown that there is a lack of basement membrane over the surface of lattice lesions and replacement with astrocytes. [3] Pathophysiology [eyewiki.aao.org]

Although the etiology of familial retinal detachment associated with lattice degeneration is thought to be polygenic and/or multifactorial [8], the pathophysiological mechanism and underlying genetic factors remain unknown. [journals.plos.org]

Preventive treatment of lattice degeneration has not been shown to prevent retinal detachment, but lattice degeneration should be monitored. [bouldereyesurgeons.com]

[…] and Early detection There are no effective methods of preventing the vitreous changes that lead to RRD. [ejournalofophthalmology.com]

Lasers or cryoretinopexy are sometimes used prophylactically to help prevent retinal detachments. [retinahawaii.com]

In certain cases, laser treatment is performed to prevent retinal tears and detachment in asymptomatic high-risk individuals. Stephen Ong Tone [retinacanada.com]

Such an approach would also help in formulating guidelines for the prophylactic treatment of this condition in the prevention of retinal detachment. [ijo.in]