Fundoscopy showed optic nerve head pallor, retinal vascular attenuation, macular staphylomata, varying degrees of pigmentary disturbance and white spots, all features recognised to lie within the clinical spectrum of LCA. [iovs.arvojournals.org]

Examination of the posterior segment of the eye showed optic disc pallor, retinal vascular attenuation, varying degrees of macular staphyloma, widespread pigmentary disturbance heaviest equatorially and numerous fundal white spots. [nature.com]

Most patients present optic disc pallor, vascular attenuation and pigmentary retinal changes. [wjgnet.com]

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The protocols can reduce blood clots, nausea, infection, muscle atrophy, hospital stay and more. [crainscleveland.com]

The book is divided into 13 sections covering: Principles of ophthalmology Ophthalmic History and Examination Correction of Refractive errors Basic Eye Examination Acute ophthalmology Gradual loss of vision Paediatric ophthalmology Eyelid, lacrimal and [books.google.com]

LCA 10 leads to progressive loss of vision causing most patients to lose their sight in the first few years of life. To date, there are no treatments approved or products in clinical development that treat the underlying cause of the disease. [globenewswire.com]

Main clinical features congenital non evolutive blindness, with pendular nystagmus, anterior keratoconus, roving eye movements, absent ocular pursuit and eye poking, severe photophobia, hypermetropia, normal fundus at birth followed by salt and pepper [genatlas.medecine.univ-paris5.fr]