Renal function generally stabilized or improved and the anemia improved. [ncbi.nlm.nih.gov]

Several days later, he returned with severe left upper quadrant pain and was admitted to the surgical service for further evaluation. A splenectomy was performed for a suspected splenic lymphoma. [ncbi.nlm.nih.gov]

Both have corneal opacity, splenomegaly and mild hemolytic anemia. The brother, the older of the 2, also has significant proteinuria. [ncbi.nlm.nih.gov]

Signs and symptoms In complete LCAT deficiency patients may present with Anemia, Corneal opacities, Hepatosplenomegaly, renal insufficiency while in partial deficiency (fish eye disease) corneal opacities is the main finding with hepatosplenomegaly. [ipfs.io]

A 20-year-old male of Indian extraction presented with visual impairment principally due to bilateral diffuse punctate corneal infiltration, with peripheral ring opacities. [tandfonline.com]

Physical examination revealed a tender guarded abdomen, no icterus, and bilateral corneal "arcus senilis"-like changes. Laboratory workup showed a mild normocytic, normochromic anemia; and target cells were seen in the peripheral blood smear. [ncbi.nlm.nih.gov]

It is characterized by cloudiness of the clear front surface of the eye ( corneal opacities), a shortage of red blood cells ( hemolytic anemia ), and kidney failure. [rarediseases.info.nih.gov]

The condition is characterized by corneal disorders, anemia, protein in the urine and ultimately, kidney failure. [checkorphan.org]

failure and vision deterioration are some of the potential complications of Complete LCAT Deficiency Disorder. [dovemed.com]

The kidney problems get worse over time and may eventually lead to kidney failure. [ghr.nlm.nih.gov]

In 2 patients hypertriglyceridemia and hypercholesterolemia were present, the latter because of an increase in unesterified cholesterol. [ncbi.nlm.nih.gov]

Patients may present with HDL deficiency, corneal opacification, hemolytic anemia, hypertension, hypertriglyceridemia, and proteinuria. [emedicine.com]

Absence of this enzyme can result in a rare syndrome that includes diffuse corneal opacities, normocytic normochromic anemia, proteinuria, renal failure, and premature arteriosclerosis. [ncbi.nlm.nih.gov]

The gene encoding for LCAT has been mapped to chromosome 16q22.1, and several mutations of this gene cause LCAT deficiency which is inherited as an autosomal recessive trait and which is characterized by corneal opacities, normochromic normocytic anemia [ncbi.nlm.nih.gov]