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Ledderhose Disease

Plantar Fibromatosis


  • Lesions typically present in middle-aged or elderly individuals and involve the medial plantar fascia.[mdedge.com]
  • Signs and symptoms : Plantar fibromatosis is most frequently present near the highest point of the arch, on the medial border of the sole.[xpertdox.com]
  • The nodules had been present for more than 4 years but were gradually enlarging and the patient felt discomfort while walking.[clinmedjournals.org]
  • Fausto de Souza D, Micaelo L, Cuzzi T, Ramos-E-Silva M (2010) Ledderhose disease: an unusual presentation. J Clin Aesthet Dermatol 3:45–47 PubMed Google Scholar 9.[link.springer.com]
  • Ledderhose Disease: An Unusual Presentation. The journal of Clinical and Aesthetic Dermatology, 3.[physio-pedia.com]
  • Caucasians of northern European descents tend to fall victim to this and other fibrotic diseases more often than other ethnicities, while Asians are rarely affected.[kimfoot.com]
  • MICHAEL ATHENS GA Collagenase injection 26 JOSEPH FRANK ROSWELL GA Needle Fasciotomy 14 KROPP WILLIAM SAVANNAH GA Fasciectomy 16 DUNCAN JAMES AUGUSTA GA Collagenase injection 19 KIRKPATRICK DELORES ROSWELL GA Needle Fasciotomy 15 MULLEN PATRICK POST FALLS[dupuytrens.org]
  • This doctor confirmed it was indeed, Plantar fibroma (my worst nightmare). He said, if the 1st round of cortisone shot worked for 9 months then this one would too. He did not explain anything about this condition. He gave me the shot.[plantarfibroma.blogspot.com]
Skin Lesion
  • Surgical treatment was suggested, so, in pneumoischemia, we made a surgical incision including the skin lesion. Then we proceeded to sculpture the anterolateral thigh fasciacutaneous flap to obtain adequate soft tissue coverage.[ncbi.nlm.nih.gov]
  • Rothstein AR 1992 43 Plantar fibromatosis and bilateral flexion contractures: a review of the literature. ( 1622023 ) Classen DA...Hurst LN 1992 44 Sonography of plantar fibromatosis. ( 1663131 ) Reed M...Griswold VJ 1991 45 Plantar fibromatosis and hyperkeratosis[malacards.org]


  • An ulcerative nodule had been noted in the last 16 months on the right foot, in the absence of trauma, not responsive to conservative treatment, so we decided to perform a biopsy.[ncbi.nlm.nih.gov]
  • This includes discussions on the options for a treatment and a personal account of treatment via Radiotherapy in the UK, and interviews with other patients.[dupuytrens-society.org.uk]
  • Treatment People with Ledderhose disease have a few different options for treatment, including natural remedies. Individuals with the condition should talk to a doctor before starting any course of treatment.[medicalnewstoday.com]
  • Learn more Radiotherapy We’re always investing in the most advanced proven technologies and evidenced based treatments to deliver targeted radiotherapy treatments.[genesiscare.co.uk]
  • Treatment options have been limited and surgical treatment of the nodules often recommended. The recurrence rate after excision is unacceptably high. Dr.[southtexaspodiatrist.com]


  • What is the Prognosis of Plantar Fibromatosis? (Outcomes/Resolutions) The prognosis of Plantar Fibromatosis depends on the severity of the condition With proper treatment, the prognosis is generally good.[dovemed.com]
  • The condition has a good prognosis, although slow progression is not uncommon. Fasciectomy has been shown to reduce the rate of recurrence. [1] [3] Last updated: 7/3/2018[rarediseases.info.nih.gov]
  • Signal characteristics T1: iso to low signal compared with muscle 1,2 T1 C (Gd): demonstrates variable contrast enhancement 4 T2: low to intermediate signal compared with muscle 1,2 Treatment and prognosis Initially orthotics and local steroid injection[radiopaedia.org]
  • What is the prognosis for Dupuytren’s contracture? The prognosis depends on its genetic expression. Individuals from families with many cases of Dupuytren’s contracture requiring surgery will most likely have a difficult course.[healio.com]
  • Dupuytren-like fibrotic tissue can occur on the sole of the foot (Ledderhose disease) and penis (Peyronie’s disease). 2,3 In patients with these coexisting conditions, prognosis is generally worse. 4 With the hands, bilateral involvement is common, although[mdedge.com]


  • Co-authored by: Jan Van Der Bauwhede MD - Discussion: - disorder of unknown etiology characterised by local proliferation of abnormal fibrous tissue in the plantar fascia - this tissue is locally aggressive and progressively replaces the normal plantar[wheelessonline.com]
  • Plantar fibromatosis is associated with other fibroproliferative disorders such as: Dupuytren disease (also known as palmar fibromatosis ) is seen in 40% (range 10-65%) of patients keloids Peyronie disease Unfortunately, exact etiology of plantar fibromatosis[radiopaedia.org]
  • Bilateral involvement is seen in 25% of patients. [8] [4] Due to the lack of information about the formation of this condition, the etiology is still controversial.[physio-pedia.com]
  • 1 The etiology, evaluation, and management of plantar fibromatosis. ( 30774465 ) 2019 2 T2 signal intensity as an imaging biomarker for patients with superficial Fibromatoses of the hands (Dupuytren's disease) and feet (Ledderhose disease) undergoing[malacards.org]


  • His special interests include epidemiology of hand and wrist disorders and Dupuytren’s contracture. He has published over 150 scientific articles and has authored multiple national reports and NICE-accredited clinical pathways.[books.google.com]
  • […] the metatarsophalangeal joints and the bases of the proximal phalanges. [5] [3] [6] Figure 1: Plantar and medial views of the foot demonstrating the origin and insertion of the plantar fascia and the location of nerves in proximity to the heel. [5] Epidemiology[physio-pedia.com]
  • Epidemiology While only about 7% percent of the general population is affected, about 15-20% of patients with diabetes will get Dupuytren's disease.[diapedia.org]
  • "Epidemiology of Dupuytren's disease". Journal of Clinical Epidemiology. 53 (3): 291–6. doi : 10.1016/s0895-4356(99)00145-6. PMID 10760640. "Dupuytren's Contracture".[en.wikipedia.org]
  • […] between corpora cavernosa and tunica albuginea, causing curvature towards side of lesion and restricting movement of these structures during erection Etiology may be related to Parc protein ( BJU Int 2010;106:1706 ) or Wnt2 ( J Sex Med 2012;9:1430 ) Epidemiology[pathologyoutlines.com]
Sex distribution
Age distribution


  • In very severe diathesis flaps should be considered in an earlier phase to prevent multiple procedures and early recurrence.[ncbi.nlm.nih.gov]
  • Physiotherapy : stretching exercises, massage, and splints to prevent contractures or stiffening of the foot. Orthotics : special inserts in shoes may reduce pressure on the lump and reduce pain when walking.[dupuytrens-society.org.uk]
  • Diet There does not seem to be any specific diet that will help prevent the disorder. Drinking alcoholic beverages only in moderation may reduce the risk of forming nodules. It may also help prevent and avoid injuries to the feet.[medicalnewstoday.com]
  • Administering gadolinium also helps in preventing recurrences. Skin grafts have been shown to prevent recurrence of the disease. Many patients benefit with shock waves in pain control.[xpertdox.com]

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