Signs and symptoms : Plantar fibromatosis is most frequently present near the highest point of the arch, on the medial border of the sole. [xpertdox.com]

Lesions typically present in middle-aged or elderly individuals and involve the medial plantar fascia. [mdedge.com]

The nodules had been present for more than 4 years but were gradually enlarging and the patient felt discomfort while walking. [clinmedjournals.org]

[5] Options for intervention include radiation therapy, cryosurgery, treatment with collagenase clostridium histolyticum, or surgical removal only if discomfort hinders walking. [6] Signs and symptoms [ edit ] Plantar fibromatosis is most frequently present [en.wikipedia.org]

Ledderhose Disease: An Unusual Presentation. The journal of Clinical and Aesthetic Dermatology, 3. [physio-pedia.com]

• Nodular Fibrosis

  It is a hyperproliferative disorder characterized by nodular fibrosis of the plantar fascia. It may occur at any age, with the greatest prevalence at middle age and beyond and men are affected twice as often as women. [clinmedjournals.org]

This includes discussions on the options for a treatment and a personal account of treatment via Radiotherapy in the UK, and interviews with other patients. [dupuytrens-society.org.uk]

Complications Ledderhose disease treatment complications, whether medical or surgical, often involve recurrence or incomplete treatment of the primary lesion. [emedicine.medscape.com]

After a thorough examination, your board certified podiatrist will be able to determine the best treatment for you. [jerseyshorefootdoctor.com]

Series, Review of the Literature, and a Novel Descriptive Appearance Termed the "Comb Sign". ( 29603334 ) Cohen BE...McKenzie GA 2018 4 Current Concepts Review: Plantar Fibromatosis. ( 29619843 ) Espert M...Baumhauer JF 2018 5 Current concepts about treatment [malacards.org]

[…] are the treatment of choice. [radiopaedia.org]

What is the Prognosis of Plantar Fibromatosis? (Outcomes/Resolutions) The prognosis of Plantar Fibromatosis depends on the severity of the condition With proper treatment, the prognosis is generally good. [dovemed.com]

Signal characteristics T1: iso to low signal compared with muscle 1,2 T1 C+ (Gd): demonstrates variable contrast enhancement 4 T2: low to intermediate signal compared with muscle 1,2 Treatment and prognosis Initially orthotics and local steroid injection [radiopaedia.org]

The condition has a good prognosis, although slow progression is not uncommon. Fasciectomy has been shown to reduce the rate of recurrence. [1] [3] Last updated: 7/3/2018 [rarediseases.info.nih.gov]

What is the prognosis for Dupuytren’s contracture? The prognosis depends on its genetic expression. Individuals from families with many cases of Dupuytren’s contracture requiring surgery will most likely have a difficult course. [healio.com]

Dupuytren-like fibrotic tissue can occur on the sole of the foot (Ledderhose disease) and penis (Peyronie’s disease). 2,3 In patients with these coexisting conditions, prognosis is generally worse. 4 With the hands, bilateral involvement is common, although [mdedge.com]

Co-authored by: Jan Van Der Bauwhede MD - Discussion: - disorder of unknown etiology characterised by local proliferation of abnormal fibrous tissue in the plantar fascia - this tissue is locally aggressive and progressively replaces the normal plantar [wheelessonline.com]

Plantar fibromatosis is associated with other fibroproliferative disorders such as: Dupuytren disease (also known as palmar fibromatosis ) is seen in ~40% (range 10-65%) of patients keloids Peyronie disease Unfortunately, exact etiology of plantar fibromatosis [radiopaedia.org]

Bilateral involvement is seen in 25% of patients. [8] [4] Due to the lack of information about the formation of this condition, the etiology is still controversial. [physio-pedia.com]

[…] features ( eMedicine ) Penile fibromatosis (Peyronie's) Fibrous thickening of dermis and Buck's fascia between corpora cavernosa and tunica albuginea, causing curvature towards side of lesion and restricting movement of these structures during erection Etiology [pathologyoutlines.com]

Up to date information is provided on the epidemiology, biology, and pathology of the disease. The principles and specifics of treatment are explored in detail. [books.google.com]

Epidemiology While only about 7% percent of the general population is affected, about 15-20% of patients with diabetes will get Dupuytren's disease. [diapedia.org]

"Epidemiology of Dupuytren's disease". Journal of Clinical Epidemiology. 53 (3): 291–6. doi : 10.1016/s0895-4356(99)00145-6. PMID 10760640. ^ "Dupuytren's Contracture". [en.wikipedia.org]

[…] between corpora cavernosa and tunica albuginea, causing curvature towards side of lesion and restricting movement of these structures during erection Etiology may be related to Parc protein ( BJU Int 2010;106:1706 ) or Wnt2 ( J Sex Med 2012;9:1430 ) Epidemiology [pathologyoutlines.com]

Plantar fibromatosis, as well as Dupuytren’s contracture, has no clear pathophysiologic factors. [podiatrytoday.com]

Administering gadolinium also helps in preventing recurrences. Skin grafts have been shown to prevent recurrence of the disease. Many patients benefit with shock waves in pain control. [xpertdox.com]

Physiotherapy : stretching exercises, massage, and splints to prevent contractures or stiffening of the foot. Orthotics : special inserts in shoes may reduce pressure on the lump and reduce pain when walking. [dupuytrens-society.org.uk]

Diet There does not seem to be any specific diet that will help prevent the disorder. Drinking alcoholic beverages only in moderation may reduce the risk of forming nodules. It may also help prevent and avoid injuries to the feet. [medicalnewstoday.com]

CONCLUSIONS: Radiotherapy is effective in treating ML and may prevent otherwise necessary surgical interventions. Nodules, cords and symptoms regress, but long-term outcome of at least 5 years has to be awaited. [ncbi.nlm.nih.gov]