As many of the presenting symptoms can be non-specific, there may be a delay in diagnosis. LP can, however, be diagnosed in a multitude of ways. [cancertherapyadvisor.com]

We present an unusual case of gastric linitis plastica and peritoneal carcinomatosis as first manifestations of an occult breast cancer. [hindawi.com]

The average age upon presentation was 75 years (range 59–87 years). All patients were symptomatic at presentation. [ncbi.nlm.nih.gov]

The mucosa can, however, also appear normal, which requires high clinical suspicion in further workup. The antrum and pylorus are most commonly involved in LP, while the fundus is the least involved. [cancertherapyadvisor.com]

Treatment for linitis plastica in the stomach The main treatments for linitis plastic are surgery or chemotherapy. You might also have radiotherapy to help relieve your symptoms. Unfortunately, most people won't be able to have surgery. [cancerresearchuk.org]

Sometimes an endoscopic ultrasound is useful to establish the diagnosis and in guiding treatment. The treatment for linitis plastica is a controversial issue. [ncbi.nlm.nih.gov]

Prognosis Gastric LP has a very poor prognosis due to the frequent occurrence of peritoneal dissemination, lymphatic invasion and extension toward neighboring organs. The 5-year survival rate is around 10-20% in Japan and Europe. [orpha.net]

Poorer prognosis has been reported by some authors [13] in comparison with other histotypes, while others have demonstrated equivalence of the prognosis in early stages [38] and in advanced stages after stage-adjustment [39]. [wjso.biomedcentral.com]

Conclusions: Gastric LP is associated with a poor prognosis. Early diagnosis and adherence to multimodal therapy may improve survival after surgical resection. [ascopubs.org]

LP is an uncommon and aggressive form of gastric carcinoma with a high rate of metastatic disease at the time of diagnosis, and the diagnosis is delayed owing to sparing of the gastric mucosal layer by the malignancy; therefore, LP carries a poorer prognosis [academic.oup.com]

Patients with LP have a poor prognosis, with a 5-year survival of less than 10%. Early diagnosis of LP is critical to the patient’s outcome, though that can be extremely challenging. [cancertherapyadvisor.com]

Etiology LP is generally a sporadic disease but familial cases have been described. Etiology is unknown. [orpha.net]

Summary Epidemiology Gastric LP accounts for about 10% of all gastric cancers but the exact prevalence in the general population is unknown. [orpha.net]

A comprehensive analysis of the epidemiology and clinical characteristics of anti-LRP4 in myasthenia gravis. J Autoimmun 2014;52:139-145. 5. Sun F, Ladha SS, Yang Li, Liu Q, Shi SX, Su N, et al. [jkna.org]

These characteristics are in line with published epidemiology of linitis plastica.4,12,13 Piessen et al also found in their study a younger age at diagnosis with 53.1% of patients below 60 years of age diagnosed in signet ring cell carcinoma group versus [dovepress.com]

Giving up smoking improves your overall health and prevents heart attacks. [mayoclinic.org]

Aside from treating cancer cells in the stomach, the goal of treatment is to prevent the cells from spreading. Stomach cancer, when left untreated, may spread to the: lungs lymph nodes bones liver Stomach cancer alone can’t be prevented. [healthline.com]

Rekomendatsii Ukrainskoi asotsiatsii kardiolohiv z profilaktyky ta likuvannia arterialnoi hipertenzii [Recommendations of Ukrainian Association of Cardiology on prevention and treatment of hypertension]. [zmj.zsmu.edu.ua]

[…] eating a healthful diet low in salt limiting alcohol exercising regularly managing stress levels maintaining a healthy weight quitting smoking Treatment for mitral stenosis may include: taking diuretics to reduce fluid buildup using blood thinners to prevent [medicalnewstoday.com]

In our case, the absence of primitive lesion prevented any possibility of the histological subdefinition, although the lobular histological subtype is the most common cause of metastatic gastric linitis plastica caused by breast cancer [4]. 3. [hindawi.com]