A 75-year-old female presented for left total hip reimplantation and suffered pulseless electrical activity arrest upon lateral positioning and administering vancomycin. Resuscitation was achieved according to Advanced Cardiac Life Support protocol. [ncbi.nlm.nih.gov]

Case presentation: We present a case that displays the unique therapeutic challenges of treating a patient who developed both LVOT obstruction and mitral PVL after undergoing surgical aortic and mitral valve replacement (MVR). [arizona.pure.elsevier.com]

• Intravenous Administration

  On cardiac catheterization, a left ventricular peak systolic outflow gradient of 50 mm Hg was noted; this decreased to 10 mm Hg following intravenous administration of 100 mg of cibenzoline. [ncbi.nlm.nih.gov]

• Pathologist

  Street SW, Rochester, MN 55905, USA; ommen.steve{at}mayo.edu Statistics from Altmetric.com Fifty years ago, the first modern reports of what we now recognise as hypertrophic cardiomyopathy (HCM) were written by a surgeon, Sir Russell Brock, 1 and a pathologist [heart.bmj.com]

• Persistent Vomiting

  Case Reports Case 1 A 65-year-old male, hypertensive for 6 years on treatment with metoprolol 25 mg once daily, was admitted under surgical oncology with complaints of persistent vomiting for 20 days with a history of melena and exertional dyspnea for [jiaecho.org]

• Melena

  Case Reports Case 1 A 65-year-old male, hypertensive for 6 years on treatment with metoprolol 25 mg once daily, was admitted under surgical oncology with complaints of persistent vomiting for 20 days with a history of melena and exertional dyspnea for [jiaecho.org]

• Heart Disease

  disease in pediatric and adult patients. [books.google.de]

  Congenital Heart Disease in Adults. 2nd ed. Philadelphia, Pa: WB Saunders Co; 1998 : 91–128. Google Scholar 101 Child JS. Echocardiographic evaluation of the adult with postoperative congenital heart disease. In: Otto CM, ed. [circ.ahajournals.org]

• Systolic Murmur

  Four hours after thrombolysis she developed acute pulmonary oedema and a new systolic murmur. It was presumed she had acute mitral regurgitation secondary to a ruptured papillary muscle, ischaemic dysfunction or an acute ventricular septal defect. [ncbi.nlm.nih.gov]

  […] anterior motion of the the mitral vale important to recognise as can contribute to a low output state that gets worse with inotropic support ASSESSMENT History hypertenison post AVR known LVH or HOCM increasing inotropes no tamponade Examination late systolic [lifeinthefastlane.com]

  A newly detected systolic murmur in the left lower sternal border may be noticed upon physical examination; however a definitive diagnosis would require an echocardiographic examination. [kjim.org]

  A grade III/IV systolic murmur was described at the right sternal border. Aside from dyspnea on exertion, our patient had no additional cardiac symptoms at presentation. [ommegaonline.org]

  Cardiac examination revealed a Grade 2/6 cresendo-decrescendo systolic murmur heard in the left third intercostal space close to the sternum. Except for hemoglobin of 10 g%, other biochemical investigations were within normal limits. [jiaecho.org]

• Heart Murmur

  Other forms of LVOTO are often asymptomatic and may be detected by the presence of a heart murmur or abnormalities on ECG. Chest pain, dyspnea, and palpitations occur with increased activity as the degree of obstruction worsens. [mhmedical.com]

  murmurs and other sounds (Medical Encyclopedia) Patent ductus arteriosus (Medical Encyclopedia) Ventricular septal defect (Medical Encyclopedia) [ Read More ] [icdlist.com]

  Patients with severe hypertrophic obstructive cardiomyopathy (HOCM, or outflow tract obstruction) may have a heart murmur. [163.178.103.176]

  murmurs, sudden cardiac death! [slideplayer.com]

• S4 Gallop

  S4 gallop is common. Aortic coarctation Absent or mild brachial to femoral pulse delay. 0-1/6 paraspinal MSM may be present. Significantly decreased/absent and delayed femoral pulses. 2/6 paraspinal MSM or continuous murmur. [circ.ahajournals.org]

• Exertional Chest Pain

  chest pain; NYHA, New York Heart Association dyspnoea class; FHHCM, family history of hypertrophic cardiomyopathy; FHSCD, family history of sudden cardiac death; ABPR, abnormal blood pressure response during upright exercise; Peak VO 2 (%), percentage [academic.oup.com]

• Left Axis Deviation

  ECG: Findings also may include right or left axis deviation, conduction abnormalities, sinus bradycardia with ectopic atrial rhythm and atrial enlargement. Voltage criteria for LVH alone are nonspecific and are often seen in normal young adults. [patient.info]

  axis deviation that is indistinguishable from the findings in severe valvar aortic stenosis. [circ.ahajournals.org]

• Cardiac Output Decreased

  As a net result, cardiac output decreases and hypotension worsens which further activates the sympathetic system. This process can continue to deteriorate until the cycle is interrupted. [jiaecho.org]

Swift intervention with transesophageal echocardiography revealed the tru pathology altering her intraoperative treatment and her subsequent chronic treatment for her heart condition. [ncbi.nlm.nih.gov]

Following neoadjuvant concurrent chemoradiation treatment, the patient underwent left lower lobectomy and mediastinal lymphadencetomy. [kjim.org]

The long-term prognosis is excellent. [ncbi.nlm.nih.gov]

Results LV obstruction and prognosis Of the 526 study patients, 141 (27%) had LV obstruction. [onlinejacc.org]

Untreated, this subset of patients has a poor prognosis, with one study reporting more than 50 percent to worsen symptomatically and 11 percent dying by four- year follow-up. [advances-in-medicine.net]

Four-year recurrence rate and prognosis of the apical ballooning syndrome. J Am Coll Cardiol 2007; 50 : 448–452. 17. Singh K, Carson K, Shah R, Sawhney G, Singh B, Parsaik A, et al. [jstage.jst.go.jp]

Incidence of LVOTO related to the mechanism of the mitral insufficiency and to the etiology demonstrates a direct relation to preoperative mitral valve prolapse (posterior leaflet /- anterior leaflet) of degenerative origin. [ncbi.nlm.nih.gov]

Keywords Adolescent — Cardiac Surgical Procedures — Child — Child, Preschool — Humans — Infant — Mitral Valve Insufficiency/complications/surgery — Reoperation — Retrospective Studies — Risk Factors — Treatment Outcome — Ventricular Outflow Obstruction/etiology [archive-ouverte.unige.ch]

LVOT obstruction can be managed medically or invasively with surgical or percutaneous methods depending on the etiology and severity. [bmccardiovascdisord.biomedcentral.com]

Choi, and Kim: Dynamic left ventricular outflow tract obstruction without basal septal hypertrophy, caused by catecholamine therapy and volume depletion Abstract Hypertrophic cardiomyopathy (HCM) with hypertrophy of the basal septum is the most common etiology [kjim.org]

He has since completed further training in emergency medicine, clinical toxicology, clinical epidemiology and health professional education. [lifeinthefastlane.com]

Epidemiology Left ventricular outflow tract obstruction (LVOTO) occurs in 2.8 of 10,000 live births, accounting for 3 to 6 percent of congenital heart defects. [mhmedical.com]

Epidemiology HCM is the most common genetic cardiovascular disease. HCM is generally inherited as an autosomal dominant trait with variable penetrance and expressivity. A minority of cases reflect a sporadic, non-familial form of the disease. [patient.info]

Epidemiology of hypertrophic cardiomyopathy-related death: revisited in a large non-referral-based patient population. Circulation 2000 ;102: 858 - 864 31. Olivotto I, Cecchi F, Casey SA, Dolara A, Traverse JH, Maron BJ. [nejm.org]

Epidemiology and clinical profile of takotsubo cardiomyopathy. Circ J 2014; 78 : 2119–2128. 33. Owa M, Aizawa K, Urasawa N, Ichinose H, Yamamoto K, Karasawa K, et al. [jstage.jst.go.jp]

The pathophysiology, treatment, and role of intraoperative echocardiography of dynamic left ventricular outflow tract obstruction are discussed. [ncbi.nlm.nih.gov]

It is imperative, therefore, that the pathophysiologic processes involved in DLVOTO be fully understood in order to initiate safe and appropriate therapy in critically ill patients.Our presentation and discussion focus on a hypotensive critically ill [karger.com]

Pathophysiology Obstruction at any level causes increased left ventricular systolic pressure and wall stress and consequent left ventricular hypertrophy. Left ventricular hypertrophy produces subendocardial ischemia and diastolic dysfunction. [mhmedical.com]

Stress (Takotsubo) cardiomyopathy: A novel pathophysiological hypothesis to explain catecholamine-induced acute myocardial stunning. Nat Clin Pract Cardiovasc Med 2008; 5 : 22–29. 28. [jstage.jst.go.jp]

As such, subvalvular left ventricular outflow obstruction complicating valvular aortic stenosis is a potentially preventable cause of persistently high gradients that remains relatively frequently encountered after AVR. [ncbi.nlm.nih.gov]

[…] exam CURRENT PHARMACY TABLES that highlight indications, toxic effects, and drug interactions sections that present TYPICAL INDICATION CLINICAL SCENARIOS EXTENSIVELY EDITED CHAPTERS on cardiology, pulmonology, nephrology, critical care, geriatrics, preventive [books.google.de]

Antibiotic medications are prescribed to prevent bacterial endocarditis, a potentially life-threatening condition. [163.178.103.176]

Patients with multiple risk factors for sudden death benefit from implantable cardioverter defibrillator (ICD) implantation for primary prevention. [patient.info]