CASE PRESENTATION: A 38-year-old Thai woman with systemic lupus erythematosus and myasthenia gravis treated with prednisolone and azathioprine presented to our hospital with low-grade fever, diarrhea, and indurated skin lesions on both thighs. [ncbi.nlm.nih.gov]

• Low Fever

  The symptoms of Legionnaire’s disease range from a mild cough and low fever to rapidly progressive pneumonia, coma, and death. [microbewiki.kenyon.edu]

• Arthritis

  We report the first case, to our knowledge, of acute purulent arthritis due to Legionella pneumophila in an immunosuppressed patient. [ncbi.nlm.nih.gov]

• Ulcer

  A chronic leg ulcer was probably the port of entry for the infection. Treatment required several operations and prolonged antimicrobial treatment. [ncbi.nlm.nih.gov]

• Skin Lesion

  Treatment comprised intravenous azithromycin for 3 weeks and the skin lesions, myositis and myocarditis resolved. Oral azithromycin and ciprofloxacin were continued for 3 months to ensure eradication of the organism. [ncbi.nlm.nih.gov]

• Indurated Skin Lesion

  CASE PRESENTATION: A 38-year-old Thai woman with systemic lupus erythematosus and myasthenia gravis treated with prednisolone and azathioprine presented to our hospital with low-grade fever, diarrhea, and indurated skin lesions on both thighs. [ncbi.nlm.nih.gov]

She was initially transferred to this institution for definitive workup of presumed B cell lymphoma and, during her hospital course, suffered a relapse of L. pneumophila-associated cellulitis that responded promptly to azithromycin. [ncbi.nlm.nih.gov]

• Colitis

  The first case had been treated initially with 60 mg prednisolone for ulcerative colitis, and L. pneumophila serogroup 1 was isolated from sputum samples after cavitation of the lung lesion. [ncbi.nlm.nih.gov]

To evaluate the effectiveness of different disinfection treatments in a spa water system contaminated by Legionella pneumophila and associated with a case of Legionella pneumonia. [ncbi.nlm.nih.gov]

Treatment with antibiotics usually cures Legionella infection; however, if the resultant disease is not timely recognized and treated properly, it leads to poor prognosis and high case fatality rate. [ncbi.nlm.nih.gov]

[…] most common 3 ) and/or ground glass opacities 2 ; pure ground glass changes can also uncommonly occur those with extensively consolidated lesions can have associated cavitation 3 can have a subpleural or peribronchovascular pattern 2,8 Treatment and prognosis [radiopaedia.org]

Abstract The use of urinary antigen tests (UATs) may provide early etiology in pneumonia, and facilitates rapid and directed antibiotic treatment. [ncbi.nlm.nih.gov]

Results : Epidemiologically unrelated ST345 isolates were clearly distinguishable from the epidemic clone. [ncbi.nlm.nih.gov]

We discuss the possible mechanisms of L. pneumophila associated acute pancreatitis for which the pathophysiology is still undetermined: infection, toxin release or cytokine secretion. [ncbi.nlm.nih.gov]

[…] clinical disorders or settings where the test may be helpful Evaluation of possible legionellosis (Legionnaires disease, Pontiac fever, extrapulmonary legionella infection caused by Legionella pneumophila ) Clinical Information Discusses physiology, pathophysiology [mayomedicallaboratories.com]

The Dot/Icm secretion system was necessary for L. pneumophila to prevent the eukaryotic proliferation. [ncbi.nlm.nih.gov]

Health departments and public agencies have issued infection prevention guidelines aimed at preventing outbreaks in facilities in which Legionnaires' disease has been overlooked. [text.apic.org]

Centers for Disease Control and Prevention. [idexx.com]