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Leiomyosarcoma of the Kidney

Leiomyosarcoma of Kidney


  • In addition, our patient presented with a pulmonary embolism, which is different from the classic presentation of leiomyosarcoma.[ncbi.nlm.nih.gov]
  • One study of sarcoma patients [ 10 ], showed that many of sarcoma patients presented had thyroid disorders (goiter, thyroiditis and carcinoma). The interval between the diagnosis of the thyroid disorder and the sarcoma varied.[pubs.sciepub.com]
Congestive Heart Failure
  • Patients with pulmonary artery sarcomas present with chest pain, dyspnoea or intractable congestive heart failure. Primary pulmonary leiomyosarcomas are often asymptomatic, but patients can present with haemoptysis.[academic.oup.com]
  • Abstract A 41-year-old man presented with a large abdominal tumor that yielded, in the fine needle aspiration biopsy, dyshesive, pleomorphic malignant cells.[ncbi.nlm.nih.gov]
  • Left nephrectomy was performed after aspiration of about 1000ml bloody fluid. The renal tumor was filled with bloody fluid and necrotic mass. The weight of the kidney was 1630g. Histological diagnosis was primary leiomyosarcoma of the kidney.[jstage.jst.go.jp]
  • Presents two brand-new chapters covering urinary cytology and fine needle aspiration to keep you up to date. Covers newly described entities and application of ancillary study for precise diagnosis.[books.google.com]
  • Fine needle aspiration biopsy of primary renal synovial sarcoma. A case report. Acta Cytol 2003;47:668-72. [ PUBMED ] 5. Chen S, Bhuiya T, Liatsikos EN, Alexianu MD, Weiss GH, Kahn LB.[cancerjournal.net]
  • To confirm a diagnosis of leiomyosarcoma a fine-needle aspiration may be performed.[rarediseases.org]
Abdominal Mass
  • Case 2: A 49-year-old house wife was admitted because of left abdominal mass and pain in April 1977. A left pyelogram and retrograde pyelogram showed a displacement of the pelvis by the tumor. Aortogram showed poor vascularity in the renal mass.[jstage.jst.go.jp]
  • Usual clinical presentation mimics renal cell carcinoma with classical triad i.e. flank pain, hematuria & abdominal mass. 5 Currently available imaging systems are unable to differentiate between leiomyosarcoma & RCC, so diagnosis is usually made postoperatively[keralamedicaljournal.com]
  • Leiomyosarcoma usually present with flank pain, hematuria and an abdominal mass, thus mimicking renal cell carcinoma. Radiographic findings are non-specific and diagnosis is usually made postoperatively.[mjmsr.net]
  • We report a case of renal leiomyosarcoma in a 46 years old woman presenting with a left sided abdominal mass. Computed tomography scan of the abdomen revealed the mass to be renal in origin and involving the ipsilateral renal hilus and vein.[sciencedomain.org]
  • Case Report We present the case of 69-year-old woman who was found to have a large left abdominal mass in evaluation for diffuse abdominal pain accompanied by asthenia and nauseas.[pagepress.org]
Right Flank Pain
  • A 33-year-old male presented with right flank pain. Contrast enhanced computed tomogram (CT) of the abdomen showed 8.3 cm 7.5 cm 5.7 cm vascular mass arising from the suprarenal and hepatic segment of IVC.[archintsurg.org]
Back Pain
  • He also complained of left back pain, appetite loss and weight loss. Computed tomography revealed a large mass in the left retroperitoneum.[ncbi.nlm.nih.gov]
  • As mentioned, our patient presented with a history of intermittent lower back pain, lower extremity swelling, and weight loss.[jomi.com]
  • Tumors in the lower portion of the inferior vena cava may be associated with lower back pain and generalized swelling due to the abnormal accumulation of fluid (edema), especially in the legs and around the eyes.[rarediseases.org]
Flank Pain
  • The common signs and symptoms associated with renal sarcoma in adults include palpable mass, abdominal or flank pain and hematuria similar to those seen with large, rapidly growing renal cell carcinomas.[ncbi.nlm.nih.gov]
  • Case presentation A 70 years old male, with hypertension and ischemic disease, developed acute left flank pain. The general physician evaluated this using ultrasound, which showed a solid left renal mass.[bmcurol.biomedcentral.com]
  • No 12 [ 24 ] 2010 55 Female Flank pain Left RCC 20 16 RN No Unknown - -- 13 [ 25 ] 2011 57 Female Flank mass Left - 25 23 RN No 3 years No No 14 [ 26 ] 2011 65 Female Flank pain Right - 13 11 RN No 15 months No No 15 [ 27 ] 2012 74 Female Abd pain Left[jcmtjournal.com]
Macroscopic Hematuria
  • A 74-year-old male patient complained of turbid urine and macroscopic hematuria. He also complained of left back pain, appetite loss and weight loss. Computed tomography revealed a large mass in the left retroperitoneum.[ncbi.nlm.nih.gov]


  • Two years after the renal transplant, the patient's daughter was found to have a lesion in the transplanted kidney during workup for proteinuria.[academic.oup.com]
  • Upon workup by her primary care physician, she received a computed tomography (CT) scan of the abdomen and pelvis demonstrating a mass along the juxtarenal IVC that was biopsied and found to be consistent with leiomyosarcoma (Fig. 1).[jomi.com]
Abnormal Renal Function
Abnormal Renal Function


  • The tumor responded well to this treatment three times. He is alive and well in remission, the renal tumor decreased in size, and lung metastases became unclear more than 50 weeks after treatment was completed.[ncbi.nlm.nih.gov]


  • They are indistinguishable from other renal masses prior to surgery and are associated with an adverse prognosis.[ncbi.nlm.nih.gov]


  • Sarcoma and thyroid disorders: a common etiology? Oncol Rep. 2002; 9(4): 863-9. In article View Article [11] El-Khalfaoui K, du Bois A, Heitz F, Kurzeder C, Sehouli J, Harter P.[pubs.sciepub.com]
  • (Etiology) Currently, there are no known causes for Retroperitoneal Leiomyosarcoma As smooth muscles are found widely throughout the body, any individual is susceptible to leiomyosarcoma.[dovemed.com]
  • Phenotype / cell stem origin undifferentiated mesenchyme Embryonic origin mesoderm Etiology The tumor is composed of undifferentiated cells as illustrated by its relative lack of immunohistochemical reactivity.[atlasgeneticsoncology.org]
  • […] female preponderance is not fully known, but studies suggest that some malignancies are associated with genes located on X chromosome that escape X inactivation.[ 9 ] Renal LMS is found to occur equally on both sides and also bilaterally, however the etiology[jcmtjournal.com]


  • Definition / general Rare, 200 cases reported; 0.12% of all invasive renal malignancies Epidemiology Mean age 58 years, range 40 - 75 years; 70% women in one study Median overall survival is 25 months, 5 year overall survival is 25% ( Can J Urol 2007;[pathologyoutlines.com]
  • Epidemiology 1–2% of all malignant renal tumors. Peak incidence in the fifth decade of life. Pathology of Renal Sarcomas Histology: Leiomyosarcomas are the most common renal sarcoma, followed by liposarcomas.[urology-textbook.com]
  • Epidemiology Uterine LMS is a rare tumor. Only about 6 out of one million women will be diagnosed with this rare cancer in the U.S. annually. The average age of diagnosis is 51 years.[curesarcoma.org]
  • Epidemiology CCSK comprises 5 percent of primary pediatric renal tumors with the peak incidence in the second year of life; however, patients' ages have ranged from 2 months to 54 years. Adult cases are extraordinarily rare.[atlasgeneticsoncology.org]
  • Epidemiology, Presentation, andManagement of Retroperitoneal Leiomyomata: Systematic Literature Review andCase Report. J Minim Invasive Gynecol. 2008. 15(2): 152–160. [16] Esteban JM, Allen WM, Schaerf RH.[bjuinternational.com]
Sex distribution
Age distribution


  • Furthermore, we now better understand how to screen for this disease and prevent serious illness.[verywell.com]
  • Radiation therapy works to destroy cancer cells by depositing energy that damages their genetic material, preventing or slowing their growth and replication.[rarediseases.org]
  • This prevents pain and bleeding during systemic treatment and is associated with a better prognosis.[cancer.net]

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