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Leishmania


Presentation

  • A retrospective study was performed among patients who presented at The Sheba Medical Center between 2005 and 2014 with atypical clinical presentations of CL due to L. major.[ncbi.nlm.nih.gov]
Cervical Lymphadenopathy
  • KEYWORDS: Leishmania siamensis, parasites, visceral leishmaniasis, zoonosis, phlebotomine sand fly, Sergentomyia (Neophlebotomus) gemmea, anthropophilic, zoophilic, authochthonous, hepatosplenomegaly, cervical lymphadenopathy; sequence typing, sandflies[ncbi.nlm.nih.gov]
Hoarseness
  • Two male immunocompetent subjects who developed Leishmania mucosal lesion mimicking a laryngeal tumor presented with a several-months history of dysphonia, dyspnea, hoarseness, and odynophagia.[ncbi.nlm.nih.gov]
Odynophagia
  • Two male immunocompetent subjects who developed Leishmania mucosal lesion mimicking a laryngeal tumor presented with a several-months history of dysphonia, dyspnea, hoarseness, and odynophagia.[ncbi.nlm.nih.gov]
Thrombosis
  • In mammals, the NTPDases play important roles in the regulation of thrombosis and inflammation. In parasites of the genus Leishmania, the causative agents of leishmaniasis, two NTPDase isoforms, termed NTPDase-1 and NTPDase-2 have been described.[ncbi.nlm.nih.gov]
Cutaneous Manifestation
  • We report the first case of leishmaniasis with exclusively cutaneous manifestations caused by L. (L.) infantum chagasi in an urban area of Rio de Janeiro.[ncbi.nlm.nih.gov]
Photosensitivity
  • Zn(ii) meso-tetrakis(N-ethylpyridinium-2-yl)porphyrin (ZnTE-2-PyP4 , ZnP) is a cationic, water-soluble, zinc porphyrin-based photosensitizer whose photodynamic effect on Leishmania braziliensis was analyzed by evaluating the number of visibly undamaged[ncbi.nlm.nih.gov]
Maculopapular Rash
  • He had developed a generalized maculopapular rash on his face after initiation of highly active antiretroviral therapy.[ncbi.nlm.nih.gov]
Cutaneous Larva Migrans
  • Angela Schuster, Hannah Lesshafft, Sinésio Talhari, Silás Guedes de Oliveira, Ralf Ignatius, Hermann Feldmeier and Xiao-Nong Zhou, Life Quality Impairment Caused by Hookworm-Related Cutaneous Larva Migrans in Resource-Poor Communities in Manaus, Brazil[doi.org]
Larva Migrans
  • Angela Schuster, Hannah Lesshafft, Sinésio Talhari, Silás Guedes de Oliveira, Ralf Ignatius, Hermann Feldmeier and Xiao-Nong Zhou, Life Quality Impairment Caused by Hookworm-Related Cutaneous Larva Migrans in Resource-Poor Communities in Manaus, Brazil[doi.org]

Treatment

  • The treatment showed no considerable toxicity against mammalian cells. Therefore, the results indicated that PDT associated with ZnTE-2-PyP4 represents a promising alternative to cutaneous leishmaniasis treatment.[ncbi.nlm.nih.gov]
  • Screening for the best potential drug compounds is an early step in the process of developing effective treatments for the disease.[worldcommunitygrid.org]

Prognosis

  • […] complex and L. mexicana complex L. braziliensis may also produce espundia, a destructive mucocutaneous form Human infection through bite of Phlebotomus sand fly (smaller than mosquitoes); rarely through blood contamination Clinical presentation and prognosis[pathologyoutlines.com]
  • The presentation and prognosis will vary depending on the species involved.[dermnetnz.org]
  • Therefore, diagnostic solutions that can provide point-of-care testing, prognosis and parasite species identification are essential. Better diagnostic solutions for VL are equally pressing. VL has high rates of mortality.[finddx.org]

Etiology

  • Despite that Leishmania mexicana is the main etiological agent of cutaneous leishmaniasis (CL) in other regions of Mexico, the species causing CL in patients from Sinaloa state has not been previously established, although Leishmania braziliensis has[ncbi.nlm.nih.gov]

Epidemiology

  • Epidemiological characterization with identification of existing Leishmania species in a particular region is essential for understanding this parasitosis epidemiology.[ncbi.nlm.nih.gov]
Sex distribution
Age distribution

Pathophysiology

  • Pathophysiology After inoculation by a sand fly, promastigotes are phagocytized by host macrophages; inside these cells, they transform into amastigotes.[merckmanuals.com]

Prevention

  • Electronic address: rbregano@uel.br. 8 Department of Preventive Veterinary Medicine, Londrina State University, Londrina, PR, 86057-970, Brazil.[ncbi.nlm.nih.gov]
  • There are No Vaccines to prevent leishmaniasis. 25. PREVENTION AND CONTROL (.....contd.) 26.[slideshare.net]
  • […] for Disease Control and Prevention[medlineplus.gov]

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