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Lentigo Simplex


Presentation

  • In both conditions, an increased number of pigment-producing cells (melanocytes) is present. Lentigo simplex can occur anywhere on the body, including areas that are not exposed to sunlight.[skinsight.com]
  • A single lesion or multiple lesions (lentigines) may be present at birth or more commonly first develop in early childhood.[medicine.academic.ru]
  • In both conditions, an increased number of pigment-producing cells (melanocytes) are present. Lentigo simplex can occur anywhere on the body, including areas that are not exposed to sunlight.[skinsight.com]
  • Ink-spot lentigines present as solitary black spots, typically surrounded by solar lentigines. Ink-spot lentigines commonly affect those of Celtic heritage.[ozarkderm.com]
  • It was also revealed that compound melanosomes, similar in size and shape to giant pigment granules, were present in melanocytes.[ncbi.nlm.nih.gov]
Cat Scratch
  • scratch disease Cheilitis granulomatosa Miescher Melkerson Rosenthal Intersticial granulomatous dermatitis Crohn's disease, skin changes Connective tissue disorders Lupus erythematosus Lupus erythematodes, acute Acute neonatal lupus erythematodes Lupus[atlases.muni.cz]
Lymphedema
  • Ulcus cruris Superficial thrombosis Superficial thrombophlebitis Cutis marmorata, livedo reticularis, livedo racemosa Cryoglobulinemia Cryoglobulinemia in monoclonal gamapathy Mixed cryoglobulinemia Acrocyanosis Malignant atrophic papulosis of Degos Lymphedema[atlases.muni.cz]
Abdominal Pain
  • Foci of darkly pigmented mucosa (lower left portion of image) in the proximal and mid-esophagus, an incidental finding in an 82 year-old man undergoing endoscopy for evaluation of abdominal pain.[endoatlas.com]
Hypertension
  • Delivery Models Health Care Economics, Insurance, Payment Health Care Policy Health Care Quality Health Care Reform Health Care Safety Health Care Workforce Health Disparities Health Informatics Health Policy Hematology History of Medicine Humanities Hypertension[jamanetwork.com]
Hyperhidrosis
  • […] skin Rodent ulcer DiseasesBroken Blood Vessels telangiectasia rosacea spider veins Dermatitis Allergic Irritant CystsEar lobe PoresExcess HairExcessive Liver Spots Infections ringworm athlete foot Loss ProblemsHerpes Simplex cold sores Zoster shingles Hyperhidrosis[marcaliquida.com.ar]

Treatment

  • Treatment *Does not typically require treatment *Sunscreens may be used to prevent further development *May be permanently removed, if the affected person desires OTC Options: Sunscreen Lentigines do not typically require treatment, as lesions are benign[ozarkderm.com]
  • Peitsch Published online: 14 Jul 2015 Favourite Read & Respond COMMENTARIES BRAF in early stage melanoma: rationale for testing and treatment? Authors: M.A. Davies Published online: 14 Jul 2015 Favourite Read & Respond[bjdonline.com]
  • Skin Resurfacing cosmetic treatment Dr lentigo Picture Image on MedicineNet.com Herpes Zoster Also known as Shingles is painful viral infection of the nerves that causes rash with small blisters.[marcaliquida.com.ar]
  • If necessary, lentigines can be removed permanently through the use of chemical peels, cryotherapy, laser treatments or simple surgical excision. See smartphone apps to check your skin.[dermnetnz.org]

Prognosis

  • Thicker melanomas at discovery or those with regional lymph node metastasis have a poorer prognosis; and patients with disseminated disease at time of diagnosis have a bleak prognosis.[intechopen.com]
  • When treatment is required but cannot be provided within primary care - eg, treatment with local chemical peel or lasers (Q-switched Nd:YAG or ruby) are effective when available. [ 8, 9 ] Prognosis Lentigines tend to worsen over time but do not become[patient.info]
  • Prognosis Lentigines are benign by nature. In patients in whom lentigines are associated with systemic abnormalities or complications, the prognosis may depend on the severity of the associated conditions.[emedicine.medscape.com]
  • Keywords: Diagnosis; Melanoma; Nevi and melanomas; Pathology INTRODUCTION Early detection of malignant melanoma (MM) is critical for a good prognosis and its eventual cure.[scielo.br]

Etiology

  • (Etiology) The cause of development of Lentigo Simplex is unknown.[dovemed.com]
  • : The etiology of melanoma is unknown.[intechopen.com]
  • Epidemiology Frequency yet to be determined Etiology Present at birth or more commonly first develop in early childhood; not induced by sun or associated with any medical diseases Pathogenesis Only a few develop initially, but over time up until adult[dermpathdiagnostics.com]
  • Etiology and Pathophysiology Ephelides occur as a result of increased melanin content inside of keratinocytes, mainly seen in the basal cell layer. The number of melanocytes is normal.[unboundmedicine.com]
  • Multiple clinical and etiologic varieties exist. The distinction of a lentigo from other melanocytic lesions (eg, melanocytic nevi, melanoma ) and its role as a marker for ultraviolet damage and systemic syndromes is of major significance.[emedicine.medscape.com]

Epidemiology

  • Epidemiology and Etiology : The lesions are hereditary, occurring more commonly and more extensively in males, and they do not appear until after age 30.[intechopen.com]
  • Terminology Also called solar lentigines, age spots Epidemiology Sun exposed skin of elderly (90% of whites age 60 ); also truck drivers on sun exposed face ( J Dermatol 2008;35:146 ) Multiple large solar lentigos on upper back and shoulders suggest prior[pathologyoutlines.com]
  • Epidemiology Frequency yet to be determined Etiology Present at birth or more commonly first develop in early childhood; not induced by sun or associated with any medical diseases Pathogenesis Only a few develop initially, but over time up until adult[dermpathdiagnostics.com]
  • Epidemiology Incidence The incidence of ephelides, solar lentigines, and simple lentigines is currently unknown, with limited information on these benign entities reported in the literature.[unboundmedicine.com]
  • Epidemiology Frequency United States In America, solar lentigines are observed in as many as 90% of whites older than 60 years and in 20% of whites younger than 35 years.[emedicine.medscape.com]
Sex distribution
Age distribution

Pathophysiology

  • Etiology and Pathophysiology Ephelides occur as a result of increased melanin content inside of keratinocytes, mainly seen in the basal cell layer. The number of melanocytes is normal.[unboundmedicine.com]
  • Pathophysiology Long-term exposure to ultraviolet radiation and pollution as one ages may induce the common solar lentigo. [3] Depending on the type of lentigo present, a solitary lesion or multiple lesions can occur anywhere on the body.[emedicine.medscape.com]

Prevention

  • However, use of sunscreen may prevent new lesions from forming and existing lesions from becoming darker in the case of solar lentinges.[ozarkderm.com]
  • Currently, there are no known methods to prevent Lentigo Simplex occurrence. However, some of the risk factors may be recognized and controlled.[dovemed.com]
  • Transplantation Substance Use and Addiction Surgery Surgical Innovation Surgical Pearls Teachable Moment Technology and Finance The Rational Clinical Examination Tobacco and e-Cigarettes Toxicology Trauma and Injury Treatment Adherence United States Preventive[jamanetwork.com]
  • Prevention [ 1 ] New lesions can be prevented to some extent by sun avoidance. Clothing is more effective than sunscreens. Avoiding the excessive use of sunbeds helps to prevent tanning-bed lentigines.[patient.info]
  • General Prevention The best way to prevent ephelides and solar lentigines is sun avoidance.[unboundmedicine.com]

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