A single lesion or multiple lesions (lentigines) may be present at birth or more commonly first develop in early childhood. [medicine.academic.ru]

In both conditions, an increased number of pigment-producing cells (melanocytes) is present. Lentigo simplex can occur anywhere on the body, including areas that are not exposed to sunlight. [skinsight.com]

Ink-spot lentigo limited also to sun-exposed areas of the body, the most common presentation includes one ink-spot among an extensive number of solar lentigines. [dermpathdiagnostics.com]

• Hypertension

  Delivery Models Health Care Economics, Insurance, Payment Health Care Policy Health Care Quality Health Care Reform Health Care Safety Health Care Workforce Health Disparities Health Informatics Health Policy Hematology History of Medicine Humanities Hypertension [jamanetwork.com]

• Purpura

  /Eczematid-like purpura of Doucas and Kapetanakis Lichen aureus Angioma serpiginosum Hemosiderin hyperpigmentation Other metals Argyria Chrysiasis Arsenic poisoning Lead poisoning Titanium metallic discoloration Other Carotenosis Tar melanosis Dyschromia [zims-en.kiwix.campusafrica.gos.orange.com]

  + Thrombotic thrombocytopenic purpura of Moschowitz + Urticarial vasculitis + Vasculitis and mycotic sepsis + Chronic venous insufficiency + Venous varices + Ulcus cruris + Superficial thrombosis + Superficial thrombophlebitis + Cutis marmorata, livedo [atlases.muni.cz]

• Piebaldism

  ILDS L81.420) DiseasesDB: 34326 Pigmentation disorders/Dyschromia (L80–L81, 709.0) Hypo-/ leucism Loss of melanocytes Vitiligo Quadrichrome vitiligo Vitiligo ponctué Syndromic Alezzandrini syndrome Vogt–Koyanagi–Harada syndrome Melanocyte development Piebaldism [zims-en.kiwix.campusafrica.gos.orange.com]

• Hyperhidrosis

  […] skin Rodent ulcer DiseasesBroken Blood Vessels telangiectasia rosacea spider veins Dermatitis Allergic Irritant CystsEar lobe PoresExcess HairExcessive Liver Spots Infections ringworm athlete foot Loss ProblemsHerpes Simplex cold sores Zoster shingles Hyperhidrosis [marcaliquida.com.ar]

Workup Dermoscopic evaluation of a few lichenoid regressing solar lentigines showed a pattern similar to that of lichenoid regressing seborrheic keratosis. [3] Preferentially expressed antigen in melanoma immunostaining may be utilized to distinguish [emedicine.medscape.com]

Treatment Does not typically require treatment Sunscreens may be used to prevent further development May be permanently removed, if the affected person desires OTC Options: Sunscreen Lentigines do not typically require treatment, as lesions are benign [ozarkderm.com]

One to two treatments will be necessary. There are many non-laser treatment approaches to treat such spots. [dermcoll.edu.au]

Peitsch Published online: 14 Jul 2015 Favourite Read & Respond COMMENTARIES BRAF in early stage melanoma: rationale for testing and treatment? Authors: M.A. Davies Published online: 14 Jul 2015 Favourite Read & Respond [bjdonline.com]

Thicker melanomas at discovery or those with regional lymph node metastasis have a poorer prognosis; and patients with disseminated disease at time of diagnosis have a bleak prognosis. [intechopen.com]

When treatment is required but cannot be provided within primary care - eg, treatment with local chemical peel or lasers (Q-switched Nd:YAG or ruby) are effective when available. [ 8, 9 ] Prognosis Lentigines tend to worsen over time but do not become [patient.info]

Prognosis Lentigines are benign by nature. In patients in whom lentigines are associated with systemic abnormalities or complications, the prognosis may depend on the severity of the associated conditions. [emedicine.medscape.com]

Keywords: Diagnosis; Melanoma; Nevi and melanomas; Pathology INTRODUCTION Early detection of malignant melanoma (MM) is critical for a good prognosis and its eventual cure. [scielo.br]

The etiology of melanoma is unknown. [intechopen.com]

Epidemiology Frequency yet to be determined Etiology Present at birth or more commonly first develop in early childhood; not induced by sun or associated with any medical diseases Pathogenesis Only a few develop initially, but over time up until adult [dermpathdiagnostics.com]

(Etiology) The cause of development of Lentigo Simplex is unknown. [dovemed.com]

Etiology and Pathophysiology Ephelides occur as a result of increased melanin content inside of keratinocytes, mainly seen in the basal cell layer. The number of melanocytes is normal. [unboundmedicine.com]

Multiple clinical and etiologic varieties exist. The distinction of a lentigo from other melanocytic lesions (eg, melanocytic nevi, melanoma) and its role as a marker for ultraviolet damage and systemic syndromes is of major significance. [emedicine.medscape.com]

Terminology Also called solar lentigines, age spots Epidemiology Sun exposed skin of elderly (90% of whites age 60+); also truck drivers on sun exposed face (J Dermatol 2008;35:146) Multiple large solar lentigos on upper back and shoulders suggest prior [pathologyoutlines.com]

Epidemiology and Etiology : The lesions are hereditary, occurring more commonly and more extensively in males, and they do not appear until after age 30. [intechopen.com]

Epidemiology Frequency yet to be determined Etiology Present at birth or more commonly first develop in early childhood; not induced by sun or associated with any medical diseases Pathogenesis Only a few develop initially, but over time up until adult [dermpathdiagnostics.com]

Epidemiology Incidence The incidence of ephelides, solar lentigines, and simple lentigines is currently unknown, with limited information on these benign entities reported in the literature. [unboundmedicine.com]

Radiation lentigo is caused by local high-dose irradiation. [15] Epidemiology Frequency United States In America, solar lentigines are observed in as many as 90% of whites older than 60 years and in 20% of whites younger than 35 years. [emedicine.medscape.com]

Etiology and Pathophysiology Ephelides occur as a result of increased melanin content inside of keratinocytes, mainly seen in the basal cell layer. The number of melanocytes is normal. [unboundmedicine.com]

Pathophysiology Long-term exposure to ultraviolet radiation and pollution as one ages may induce the common solar lentigo. [5] Depending on the type of lentigo present, a solitary lesion or multiple lesions can occur anywhere on the body. [emedicine.medscape.com]

However, use of sunscreen may prevent new lesions from forming and existing lesions from becoming darker in the case of solar lentinges. [ozarkderm.com]

How can lentigines be prevented Lentigines associated with exposure ultraviolet radiation can be prevented by very careful sun protection. Clothing is more successful at preventing new lentigines than are sunscreens. [myskindoctor.co.uk]

Currently, there are no known methods to prevent Lentigo Simplex occurrence. However, some of the risk factors may be recognized and controlled. [dovemed.com]

Prevention [ 1 ] New lesions can be prevented to some extent by sun avoidance. Clothing is more effective than sunscreens. Avoiding the excessive use of sunbeds helps to prevent tanning-bed lentigines. [patient.info]