Presentation
[…] characteristic radiologic features of uremic leontiasis ossea. 6 Case Report We present case report of two patients (12-year-old girl and 29- year-old male) presenting with jaw masses. [slideplayer.com]
In conclusion, we present an unusual presentation of PFD with diffuse involvement of the cranio-facio-vertebral skeleton with leontiasis ossea and a post traumatic cervical cord contusion secondary to hyperextension injury of the cord in a compromised [doi.org]
This study presents a report on a patient with advanced hyperparathyroidism with skeletal changes compatible with leontiasis ossea. [journalrip.com]
In the present article, we describe the case of an uncooperative female patient with a brown tumor, involving the left maxillary sinus and massive thickening of the cranial vault and facial bones, secondary to severe secondary hyperparathyroidism during [ncbi.nlm.nih.gov]
Entities such as cherubism usually present at 2-3 years of age and spontaneously resolve after puberty. 8 Paget’s disease typically presents later than the current patient’s age and has a male predilection. [appliedradiology.com]
Entire Body System
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Turkish
Look up "leontiasis" at Merriam-Webster Look up "leontiasis" at dictionary.com In other languages: Spanish French Italian Portuguese Romanian German Dutch Swedish Russian Polish Czech Greek Turkish Chinese Japanese Korean Arabic Advertisements Word of [wordreference.com]
Deutsch (German) العربية (Arabic) Français (French) Русский (Russian) ಕನ್ನಡ (Kannada) 한국어 (Korean) עברית (Hebrew) Український (Ukrainian) اردو (Urdu) Magyar (Hungarian) मानक हिन्दी (Hindi) Indonesia (Indonesian) Italiano (Italian) தமிழ் (Tamil) Türkçe (Turkish [definitions.net]
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Vietnamese
Русский (Russian) ಕನ್ನಡ (Kannada) 한국어 (Korean) עברית (Hebrew) Український (Ukrainian) اردو (Urdu) Magyar (Hungarian) मानक हिन्दी (Hindi) Indonesia (Indonesian) Italiano (Italian) தமிழ் (Tamil) Türkçe (Turkish) తెలుగు (Telugu) ภาษาไทย (Thai) Tiếng Việt (Vietnamese [definitions.net]
Respiratoric
Jaw & Teeth
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Mouth Breathing
Physical examinations revealed: toggled speech (nasal speech), mouth breathing and facial change, saddle nose, nares widening, increased interdental space and mandibular enlargement. [journalrip.com]
Although he had facial deformities since early childhood, he professed only to cosmetic embarassment, nasal blockage, mouth breathing, mild snoring and progressing bowing of his shins. There were no other affected family members. [doi.org]
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Widely Spaced Teeth
Physical exam revealed marked non-tender maxillary and mandibular hypertrophy with nasal flattening, wide-spaced teeth and severe palatal changes. [file.scirp.org]
Eyes
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Visual Impairment
Leontiasis ossea can be associated with progressive proptosis, visual impairment or nasal obstruction. [doi.org]
Musculoskeletal
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Joint Subluxation
subluxations or dislocations and compressive symptoms [ 1 ]. [doi.org]
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Hand Muscle Weakness
He was discharged home on the 10 th day with residual distal hand muscle weakness and grade 4 muscle power in his legs. [doi.org]
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Neck Pain
He was able to turn over, but immediately noticed some neck pain and weakness of all four limbs. He was just able to lift his arms and move his legs from side to side. [doi.org]
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Saber Shin
He had broad forearms, sausage like fingers and bowing of both legs with saber shins (Figure 2 ). The nasal bridge was flat and elevated due to a soft tissue thickening (Figure 1 & 2 ). No café au lait spots were observed. [doi.org]
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Atlanto-Axial Instability
View Article PubMed Google Scholar Perlick L, Rolf V, Wallny T, Schmitt O: Atlanto-axial instability presenting a rare complication in fibrous dysplasia – a case report. Unfallchirurg. 2000, 103: 73-75. 10.1007/s001130050011. [doi.org]
Face, Head & Neck
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Facial Swelling
The second case represents a patient with hyperparathyroïdism, showing an unusual facial swelling as only physical symptom of the disease. [ncbi.nlm.nih.gov]
Neurologic
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Nasal Speech
Physical examinations revealed: toggled speech (nasal speech), mouth breathing and facial change, saddle nose, nares widening, increased interdental space and mandibular enlargement. [journalrip.com]
Workup
X-Ray
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Rugger-Jersey Spine
Findings in secondary (and tertiary) hyperparathyroidism are numerous: sub periosteal bone resorption, osteopenia, osteosclerosis e.g. rugger-jersey spine, soft tissue calcification, generalized increased uptake on Tc-99m pertechnetate bone scan, superior [file.scirp.org]
Hypertrophy
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Ventricular Hypertrophy
Electro-cardiogram : The conclusion from the examination was one of left ventricular hypertrophy. X-ray of skull: A.P. and Lateral views showed diffuse hyperostosis of bone with loss of differentiation between outer and inner tables [Figure - 2]. [ijo.in]
Treatment
[…] the case of an uncooperative female patient with a brown tumor, involving the left maxillary sinus and massive thickening of the cranial vault and facial bones, secondary to severe secondary hyperparathyroidism during 8 years of regular hemodialysis treatment [ncbi.nlm.nih.gov]
A medical practitioner should always be consulted for diagnosis and treatment of all medical conditions. [hospitalhelp.co.uk]
There is no treatment other than exposing the overgrown bone, and chipping away pieces, or excising entirely where possible. [en.wikipedia.org]
Prognosis
Treatment usually entails parathyroidectomy with monitoring of serum calcium, phosphate, and vitamin D levels while on appropriate replacement (calcium/vitamin D) or binding (phosphate) pharmacotherapy. 4 The prognosis is usually favorable. [appliedradiology.com]
More often, most lesions can be managed through staged procedures with overall very favorable outcomes and good long term prognosis. [skullbaseinstitute.com]
Etiology
Clinical-Medical Image: Paget disease of the bone is a chronic disorder of unknown etiology that typically results in enlarged, deformed bones due to abnormal and excessive bone remodeling. [imagejournals.org]
Indian J Ophthalmol 1969;17:166-70 Introduction The term leontiasis ossea was first coined by Virchow [6] in 1896 to describe the leonine appearance of the facial deformity in this rare condition of unknown etiology. [ijo.in]
However, nutritional and secondary hyperparathyroidism due to uremia has been suggested as major etiologies for the disease [5]. After parathyroidectomy, facial changes can be stabilized or improve mildly. [file.scirp.org]
Pathophysiology
Pathophysiological origin of the disease is not clearly understood. However, nutritional and secondary hyperparathyroidism due to uremia has been suggested as major etiologies for the disease [5]. [file.scirp.org]
Prevention
Hence, early recognition and treatment of leontiasis ossea can prevent its complications. Please cite this paper as: Raffiei Jelodar H, Yarmohamadi M, Baghai Wadji M, Babaei MR. Leontiasis ossea; a rare presentation of secondary hyperparathyroidism. [journalrip.com]
Early recognition andconfident diagnosisof ULO is essential to prevent progression to facial disfigurement andavoid invasive procedures. [posterng.netkey.at]
During hemodialysis patients often develop numerous comorbid conditions that may interfere with the existing disease and prevent further treatment, as was the reported case. [ncbi.nlm.nih.gov]
Ultimately, early recognition of incipient uremic leontiasis ossea clinically and on imaging is essential to prevent progression to severe disfigurement that can result from prolonged untreated secondary hyperparathyroidism [12]. [file.scirp.org]
Hence, CKD‐MBD patients should be educated about their illness, early prevention, multidisciplinary early diagnosis, and treatment plans, thereby improving their quality of life and long‐term survival.24 We hope this case report will highlight the awareness [asbmr.onlinelibrary.wiley.com]