3,6) The rarest pattern--and that most representative of an advanced disease state--is uremic leontiasis ossea which presents as marked expansion of the mandible and maxilla, occasionally with obliteration of the maxillary sinuses and splaying of the [freethesaurus.com]

Herein, we present a 31-year-old man diagnosed with uremic leontiasis ossea. [cureus.com]

This study presents a report on a patient with advanced hyperparathyroidism with skeletal changes compatible with leontiasis ossea. [journalrip.com]

[…] characteristic radiologic features of uremic leontiasis ossea. 6 Case Report We present case report of two patients (12-year-old girl and 29- year-old male) presenting with jaw masses. [slideplayer.com]

Entities such as cherubism usually present at 2-3 years of age and spontaneously resolve after puberty. 8 Paget’s disease typically presents later than the current patient’s age and has a male predilection. [appliedradiology.com]

• Falling

  Classified in this way, ninety-seven of the total of 153 cases considered were classified as true leontiasis (forty-five Type 1 and fifty-two Type 2); forty were classified as false leontiasis; and sixteen did not fall into either category. [online.boneandjoint.org.uk]

  Ueber einen Fall von Akromegalie. B. Klin. Wochenschr. 21, 371–374, 1887 Google Scholar 3. Marie P. Acromegaly. Brain 12(1–2), 59–81, 1889 CrossRef Google Scholar 4. Marie P. De l’ostheo-arthropatie hypertrophiante pneumique. [link.springer.com]

  Case report A 25 year old man was brought to the emergency room (ER) with quadriparesis after a fall from a bicycle. [doi.org]

  Another bony swelling was present on the lateral aspect of the left humerus, giving it a curved shape which had been developed following a fall. [Figure - 1]. The patient was anaemic. [ijo.in]

• Fever

  Gradual loss of vision of the left eye following headache and fever about 3 years ago and loss of vision in the right eye following headache and fever about 2 years ago. Ultimately both eyes became totally blind. 3. [ijo.in]

  Haug Browse recently published Learning/CME Learning/CME View all learning/CME CME Case 3-2019: A 70-Year-Old Woman with Fever, Headache, and Progressive Encephalopathy Caplacizumab Treatment for Acquired Thrombotic Thrombocytopenic Purpura Randomized [nejm.org]

  He denied any headaches, fever, cough, nausea, vomiting or naso-oropharyngeal discharge. As per patient's report, he had a similar presentation affecting his left jaw in 2012. [cureus.com]

• Pathologist

  Rudolf Ludwig Carl Virchow (1821-1902) was a German pathologist and statesman 5. Promoted articles (advertising) [radiopaedia.org]

  Rudolf Ludwig Carl Virchow (1821-1902) was a German pathologist and statesman. Siehe auch: Morbus Paget des Knochens kraniofaziale fibröse Dysplasie und weiter: Osteoporosis circumscripta [pacs.de]

• Surgical Procedure

  At that time, the patient recalls undergoing a left jaw “surgical procedure” at an out-of-state, outside institution but has no recollection of imaging evaluation or indication for the procedure. [cureus.com]

• Goiter

  Acromegaly and goiter in the precolumbian, mesoamerican population. J Endocrinol Invest 30, 169–170, 2007. PubMed Google Scholar Copyright information © Springer International Publishing AG 2011 Authors and Affiliations Roberto Toni 1 2 1. [link.springer.com]

• Vomiting

  These symptoms include headache, intracranial hypertension with vomiting, blindness, exophthalmos, deafness, oral breathing, eating disorder (suffocation), facial palsy, balance disorder (excessive weight, vestibulo-cochlear and cerebellar involvement [hal.archives-ouvertes.fr]

  He denied any headaches, fever, cough, nausea, vomiting or naso-oropharyngeal discharge. As per patient's report, he had a similar presentation affecting his left jaw in 2012. [cureus.com]

• Nausea

  He denied any headaches, fever, cough, nausea, vomiting or naso-oropharyngeal discharge. As per patient's report, he had a similar presentation affecting his left jaw in 2012. [cureus.com]

• Hypertension

  The patient was a 34-year-old man with end-stage renal disease, uncontrolled hypertension, and dyspnea who was referred to our hospital. [journalrip.com]

  These symptoms include headache, intracranial hypertension with vomiting, blindness, exophthalmos, deafness, oral breathing, eating disorder (suffocation), facial palsy, balance disorder (excessive weight, vestibulo-cochlear and cerebellar involvement [hal.archives-ouvertes.fr]

  […] underwent total parathyroidectomy (TPTX) with autotransplantation (AT).6 Case A 62‐year‐old male patient diagnosed with chronic glomerulonephritis was maintained on hemodialysis for the previous 12 years, twice per week, with felodipine to control his hypertension [asbmr.onlinelibrary.wiley.com]

• Contusion

  Cervical cord contusion has not been reported earlier in PFD. [doi.org]

  Cervical cord contusion has not been reported earlier in PFD. Mendeley readers Geographical breakdown Country Count As % United States 1 10% Unknown 9 90% Demographic breakdown Readers by professional status Count As % Student > Ph. D. [altmetric.com]

  Internal Medicine, 53, 1971-1976. http://dx.doi.org/10.2169/internalmedicine.53.2217 [3] Maramattom, B.V. (2006) Leontiasis Ossea and Post Traumatic Cervical Cord Contusion in Polyostotic Fibrous Dysplasia. [scirp.org]

It is possible that at this stage of the disease, the patient has tertiary hyperparathyroidism when treatment is rarely successful7. [ncbi.nlm.nih.gov]

A medical practitioner should always be consulted for diagnosis and treatment of all medical conditions. [hospitalhelp.co.uk]

Review the unique radiologic findings, differential diagnosis, treatment and follow up in uremic leontiasis ossea. [posterng.netkey.at]

HD treatment was initiated and further post-HD evaluation showed improvement of the patient's overall status. [cureus.com]

More often, most lesions can be managed through staged procedures with overall very favorable outcomes and good long term prognosis. [skullbaseinstitute.com]

Treatment usually entails parathyroidectomy with monitoring of serum calcium, phosphate, and vitamin D levels while on appropriate replacement (calcium/vitamin D) or binding (phosphate) pharmacotherapy. 4 The prognosis is usually favorable. [appliedradiology.com]

Clinical-Medical Image: Paget disease of the bone is a chronic disorder of unknown etiology that typically results in enlarged, deformed bones due to abnormal and excessive bone remodeling. [imagejournals.org]

Indian J Ophthalmol 1969;17:166-70 Introduction The term leontiasis ossea was first coined by Virchow [6] in 1896 to describe the leonine appearance of the facial deformity in this rare condition of unknown etiology. [ijo.in]

Case Presentation A 31-year-old man with a past medical history of ESRD of unknown etiology, on hemodialysis (HD) since 2004, presented to the emergency department (ED) complaining of missed dialysis. [cureus.com]

However, nutritional and secondary hyperparathyroidism due to uremia has been suggested as major etiologies for the disease [5]. After parathyroidectomy, facial changes can be stabilized or improve mildly. [file.scirp.org]

The discussion covers the phenotype spectrum, epidemiology, mode of inheritance, pathogenesis, and clinical profile of each condition, all of which is accompanied by a wealth of illustrations. [books.google.com]

The report aims to review the pathophysiology of the condition as described in the literature, the patient presentation and imaging modalities used to investigate, and classical findings seen in patients with uremic leontiasis ossea. [cureus.com]

Pathophysiological origin of the disease is not clearly understood. However, nutritional and secondary hyperparathyroidism due to uremia has been suggested as major etiologies for the disease [5]. [file.scirp.org]

Strict medical management of metabolic derangements, prevention of secondary hyperparathyroidism and adherence to hemodialysis are the best possible options to prevent this condition. [cureus.com]

Hence, early recognition and treatment of leontiasis ossea can prevent its complications. Please cite this paper as: Raffiei Jelodar H, Yarmohamadi M, Baghai Wadji M, Babaei MR. Leontiasis ossea; a rare presentation of secondary hyperparathyroidism. [journalrip.com]

Early recognition andconfident diagnosisof ULO is essential to prevent progression to facial disfigurement andavoid invasive procedures. [posterng.netkey.at]

During hemodialysis patients often develop numerous comorbid conditions that may interfere with the existing disease and prevent further treatment, as was the reported case. [ncbi.nlm.nih.gov]