This text brings together leading authorities presenting state-of-the-art clinical reviews covering the science, recognition, and treatment of the inherited metabolic epilepsies and related disorders. [books.google.com]

Acronym LIH Synonyms Leucine-sensitive hypoglycemia of infancy Disclaimer Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. [uniprot.org]

Children with HIHA frequently present seizures (most commonly atypical or absence) and learning difficulties. Neurologic abnormalities appear to be unrelated to hypoglycemia. [orpha.net]

The present report describes a mother and 2 children with leucine-induced hypoglycemia (LIH). Hypoglycemic episodes following high-protein meals first appeared at age 4-7 months. [ncbi.nlm.nih.gov]

• Hunting

  Profound hypoglycemia or a very rapid fall in blood sugar causes convulsions and final coma. hunting dog hypoglycemia a stress-related syndrome seen in dogs that are fasted before a hunt, later experiencing exhaustion and hypoglycemic seizures. juvenile [medical-dictionary.thefreedictionary.com]

• Emotional Outbursts

  Symptoms - Hypoglycemia- leucine-induced * cold and pale skin * numbness around the mouth * apprehension * heart palpitations * emotional outbursts * hand tremors * mental cloudiness * dilated pupils * sweating * fainting Causes - Hypoglycemia- leucine-induced [checkorphan.org]

• Irritability

  The classic form presents as a neonate, with the ingestion of dietary protein, with a maple syrup-like odor of cerumen, sweat and urine, irritability, poor feeding, vomiting, lethargy and a progressive encephalopathy that may result in coma with respiratory [genedx.com]

  The various signs and symptoms exhibited by the sufferers of reactive hypoglycemia include: Coma Fatigue Nausea Rhinitis Anxiety Tremors Flushing Dizziness Vomiting Sweating Irritability Confusion Numbness Headaches Depression Nervousness Panic attacks [hxbenefit.com]

• Hand Tremor

  Symptoms - Hypoglycemia- leucine-induced * cold and pale skin * numbness around the mouth * apprehension * heart palpitations * emotional outbursts * hand tremors * mental cloudiness * dilated pupils * sweating * fainting Causes - Hypoglycemia- leucine-induced [checkorphan.org]

Make the best clinical decisions with an enhanced emphasis on evidence-based practice and expert opinions on treatment strategies. Zero in on the most relevant and useful references with the aid of a more focused, concise bibliography. [books.google.com]

To evaluate the therapeutic effects and to study the mechanism of hyperinsulinism in LIH, the leucine test was repeated under treatment with diphenylhydantoin, oxprenolol (a beta-blocker), and diazoxide. [ncbi.nlm.nih.gov]

It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice . [uniprot.org]

The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment. [orpha.net]

Prognosis - Hypoglycemia- leucine-induced Like diabetes, there is no cure for reactive hypoglycemia, only ways to control it. [checkorphan.org]

Reactive Hypoglycemia Prognosis Although there are no permanent cures for Reactive hypoglycemia, maintaining a strict diet plan and regularly coordinating with the physician will allow an individual to manage the symptoms associated with this condition [hxbenefit.com]

Etiology Glutamate dehydrogenase (GDH) is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate, yielding alpha-ketoglutarate and an ammonia by-product. [orpha.net]

Summary Epidemiology Prevalence is estimated at 1 in 200,000. [orpha.net]

Patients who use insulin as a part of intensive therapy are at increased risk of hypoglycemia several hours after drinking alcohol. return to top Pathophysiology Glucagon and epinephrine are the most important immediate responders to hypoglycemia. [sharinginhealth.ca]

Rapidly find the answers you need with separate sections on diseases and disorders, differential diagnosis, clinical algorithms, laboratory results, and clinical preventive services, plus an at-a-glance format that uses cross-references, outlines, bullets [books.google.com]

The dietary supplements also recommended are intended to assist regeneration of tissue and prevent osteopenia and osteoporosis. [practicalpainmanagement.com]

Prevention - Hypoglycemia- leucine-induced Drug-induced hypoglycemia Preventing hypoglycemic insulin reactions in diabetics requires taking glucose readings through frequent blood sampling. Insulin then can be regulated based on those readings. [checkorphan.org]

[…] an excessive/ uncontrolled insulin secretion (inappropriate for the level of glycemia), asymptomatic hyperammonemia and recurrent episodes of profound hypoglycemia induced by fasting and protein rich meals, requiring rapid and intensive treatment to prevent [orpha.net]

[…] creatinine [51] (half-life of creatinine is 3.85 hours in healthy subjects [52] ) Absorbed reactive AGEs such as Pentosidine may swiftly be cleared from the blood, only to get reabsorbed and/or rapidly bind to tissue proteins to a major extend [53], preventing [waiwiki.org]