Presentation
For administration by inhalation, the compounds of the present invention are delivered in the form of an aerosol spray presentation from pressurized packs or nebulisers. [google.com]
We suggest that preceding administration of pranlukast aggravates clinical presentations of CSS. [ncbi.nlm.nih.gov]
Respiratoric
- Chronic Cough
CONCLUSIONS: Montelukast was confirmed to suppress chronic non-productive cough in CVA, whereas it was not effective in non-productive cough in AC. [ncbi.nlm.nih.gov]
Skin
- Lichenification
[…] subjects adult (male and female) with AD Montelukast 10mg OD vs. placebo Continuous adjunctive treatment: emollients, antihistamines, weak topical corticosteroids Clinical severity scores (6 signs of AD) Improvement in: • Scaling/dryness (p=0.003) • Lichenification [skintherapyletter.com]
The scoring assessed the patient-oriented outcome of severity of insomnia, as well as the distribution of the atopic dermatitis and the intensity of its appearance (e.g., erythema, edema, oozing, excoriation, lichenification, xerosis). 1 – 4 The studies [aafp.org]
Eyes
- Photophobia
The effect of montelukast in reducing burning, photophobia, secretion, and redness persisted 15 days after discontinuation. [jamanetwork.com]
Face, Head & Neck
- Facial Pain
Patients' symptoms were scored according to "facial pain", "headache", "nasal blockage", "nasal discharge", "sense of smell" and "daily activity", and measurements of peak inspiratory nasal flow were made, before and after the introduction of montelukast [ncbi.nlm.nih.gov]
Urogenital
- Microscopic Hematuria
She presented fever up to 38°C with microscopic hematuria and proteinuria, serum creatinine level of 0.7 mg/dl, and C-reactive protein of 11 mg/dl. [ncbi.nlm.nih.gov]
Treatment
Therefore, it has been suggested that antileukotrienes may be beneficial in the treatment of this disease. [ncbi.nlm.nih.gov]
Prognosis
Low expression of cyslt1r and high expression of cyslt2r mediate good prognosis in colorectal cancer. Eur J Cancer 46, 826–835 (2010). 29. Magnusson, C. et al. [nature.com]
Epidemiology
References [ 1 ] Houston, D.E., Noller, K.L., Melton III, L.J. and Selwyn, B.J. (1988) The Epidemiology of Pelvic Endometriosis. [scirp.org]
The paperwork is not onerous, and we will all benefit as we learn more about this syndrome, its epidemiology, and its expression. [asthma.partners.org]
Bozek A, Jarzab J (2013) Epidemiology of IgE-dependent allergic diseases in elderly patients in Poland. Am J Rhinol Allergy 27: e140–145. View Article Google Scholar 4. [journals.plos.org]
Pathophysiology
The pathophysiology of allergic rhinitis and its similarities to asthma suggest that these agents could play a significant therapeutic role in managing this upper airway disorder. [ncbi.nlm.nih.gov]
Cysteinyl-LTs and CysLTRs have been implicated in the pathophysiology of other inflammatory conditions including cancer, atopic dermatitis, idiopathic chronic urticaria, and cardiovascular diseases. [eurekaselect.com]
MAIN MESSAGE Leukotrienes appear to have an important role in the pathophysiology of asthma, including airway inflammation. [cfp.ca]
This is important in AD since LTB 4 and 5-oxo-ETE are chemoattractants for eosinophils,48 which as outlined above are implicated in the pathophysiology of AD. [skintherapyletter.com]
Prevention
In addition, it has been shown that LTRAs may have a potential role in preventing atherosclerosis progression. [ncbi.nlm.nih.gov]
[…] asthma symptoms and that is being studied in the prevention of lung cancer. [fpnotebook.com]