She presented initially with CS and underwent right adrenalectomy; a few years later she presented with macromastia and mastodynia, possibly due to estrogen excess from her remaining left adrenocortical masses. [ncbi.nlm.nih.gov]

According to the present invention, the peptide cleavage and global deprotection reagents used in the process of the present invention is a cocktail mixture of acid, scavengers and solvents. [google.ch]

Case Report A 78 year old man with recently diagnosed prostate cancer (Gleeson 7, non-invasive) saw his urologist two days prior to presentation. [headache.imedpub.com]

• Hunting

  Jones CU, Hunt D, McGowan DG, Amin MB, Chetner MP, Bruner DW, Leibenhaut MH, Husain SM, Rotman M, Souhami L, Sandler HM, Shipley WU. Radiotherapy and short-term androgen deprivation for localized prostate cancer. [ncbi.nlm.nih.gov]

• Hot Flushes

  The results of the QLQ-PR25 revealed that patients experienced an increase in hot flushes (p < 0.001) and erection problems and uncomfortable sexual intimacy among the sexual functioning items (p = 0.030 and p = 0.023, respectively), but day-time urinary [ncbi.nlm.nih.gov]

  In particular, low rates of hot flushes were reported. [bmcurol.biomedcentral.com]

  Common side effects Hot flushes and sweats Hot flushes are a common side effect of this treatment. During a flush, your neck and face may feel warm and look red. Flushes may last from a few seconds up to 10 minutes. [macmillan.org.uk]

  Hypoestrogenic effects (e.g. hot flushes) were reported less frequently in the dienogest group. As expected, bleeding episodes were suppressed less with dienogest than with LA. [pubmed.ncbi.nlm.nih.gov]

• Amenorrhea

  […] and subnormal plasma estradiol levels, or lack of cornification of the vaginal mucosa without an elevation in gonadotropin levels OR Hypothalamic amenorrhea in normally estrogenized women with amenorrhea or oligomenorrhea and normal plasma free testosterone [clinicaltrials.gov]

  A 43-year-old woman with a history of 5 years of amenorrhea sought help in achieving a pregnancy. Her gonadotropins were found to be elevated and thus she was diagnosed as having ovarian failure. [ncbi.nlm.nih.gov]

  Kaplan–Meier Estimates of Times to the Control of Bleeding and Persistent Amenorrhea. [nejm.org]

• Oligomenorrhea

  […] elevation in gonadotropin levels Women: Amenorrhea and subnormal plasma estradiol levels, or lack of cornification of the vaginal mucosa without an elevation in gonadotropin levels OR Hypothalamic amenorrhea in normally estrogenized women with amenorrhea or oligomenorrhea [clinicaltrials.gov]

Disease is recurrent androgen receptor-positive with distant metastases Individual has a performance status of 0-3 Uterine leiomyomas (fibroid tumors) if ALL of the following: Individual is a female 18 years of age or older Diagnosis confirmed by a workup [bcbst.com]

The use of leuprolide acetate can delay the diagnosis and treatment of leiomyosarcoma and thus may increase the risk of morbidity and affect the treatment outcome of patients with leiomyosarcoma. [ncbi.nlm.nih.gov]

Multimedia: Slideshows, Images & Quizzes Related Disease Conditions Endometriosis (Symptoms, Causes, Treatments, and Prognosis) Endometriosis implants are most commonly found on the ovaries, the Fallopian tubes, outer surfaces of the uterus or intestines [medicinenet.com]

[…] post-DL LH on 7.5 mg Greater than 2 IU/liter 6 (20) 2 IU/liter or less (proceed to lower dose) 24 (80) Study progress Dropout 3 (12) Completed three doses 21 (88) No. of subjects (%) Gender Male 6 (20) Female 24 (80) Etiology of early puberty Organic [doi.org]

Two of these AEs were considered serious, and the subjects received blood transfusions, but these events were considered not related to study drug by the investigator (alternative etiologies of suspected subacute upper gastrointestinal bleeding and metastatic [nature.com]

Large-scale, epidemiologically sound, long-term studies of the risks to women and offspring from lupron and other fertility drugs remain lacking - therefore the "informed consent process" is inherently flawed, and as such, is a misnomer. [lupronvictimshub.com]

Fertil Steril 54, 419 –427. and Warner ML ( 1997 ) Epidemiology of endometriosis. [doi.org]

The pathophysiologic mechanism by which these agents induce apoplexy remains unclear. We describe a case of pituitary apoplexy in a young woman receiving leuprolide in preparation for ovum donation. [ncbi.nlm.nih.gov]

But it neither activated anti-apoptotic pathways nor prevented follicle loss, DNA damage and apoptosis induced by these drugs. [ncbi.nlm.nih.gov]

Treatments developed for prevention will also need to have superior safety. [doi.org]

Leuprorelin also prevents stress-induced immunosuppression in animal models. Additionally, leuprorelin exhibits anticancer activity, inhibiting proliferation of prostate cancer cells in vitro. [lktlabs.com]