Leaflet thickening or regurgitation may be present. [en.wikipedia.org]

• Severe Abdominal Pain

  abdominal pain), or peripheral arterial embolism (presenting with limb coldness)).[2] Causes[edit] Libman–Sacks endocarditis occurs in association with systemic lupus erythematosus, antiphospholipid syndrome, and malignancies.[2] Systemic lupus erythematosus [en.wikipedia.org]

• Heart Disease

  Clinically significant valvular heart disease in systemic lupus erythematosus.Am J Med. 1989; 86: 407-412 Cervera R. Font J. Pare C. et al. [amjmed.com]

  Valvular heart disease is relatively rising in both congenital and acquired cases, but the autoimmune endocarditis remains rare. [actamedindones.org]

  […] role in pediatrics, diagnosing patients with valvular heart disease and other congenital abnormalities. [en.wikipedia.org]

  Note also the thickened, shortened, and fused chordae tendineae that represent remote rheumatic heart disease. [webpath.med.utah.edu]

  Disease Valvular heart disease is a well-recognized cardiac manifestation in APS and SLE. [phaonlineuniv.org]

• Heart Murmur

  Fever and a heart murmur are sometimes present. Blood cultures Echocardiography Noninfective endocarditis should be suspected when chronically ill patients develop symptoms suggesting arterial embolism. [merckmanuals.com]

  The second question came down to a left-sided systolic murmur. [forums.studentdoctor.net]

  Heart Endocarditis Noninfective endocarditis Topic Completed: 1 April 2014 Revised: 4 March 2019 Copyright: 2014-2019, PathologyOutlines.com, Inc. [pathologyoutlines.com]

  Visits to the dentist offer opportunities for bacteria to sneak into the blood and land on a heart valve. Therefore, people with severe heart murmurs should speak to their doctor about taking an antibiotic before receiving dental work. [hopkinslupus.org]

  A previously healthy 14-year-old girl was found to have a heart murmur when examined during an episode of upper respiratory tract infection. [annalspc.com]

Autoimmune workup was negative. Hematological workup showed an isolated lupus anticoagulant with normal anti-cardiolipin antibodies. Repeat lupus anticoagulant a few days later was negative. [ncbi.nlm.nih.gov]

Outline the treatment and management options available for Libman-Sacks endocarditis. [ncbi.nlm.nih.gov]

[…] options for persons with Libman–Sacks endocarditis, and treatment should focus on the underlying cause. [en.wikipedia.org]

Prognosis The prognosis of LS endocarditis requires further study, and there continues to be a need for additional research to better define prognosis. From clinical observations, the prognosis of LS is considered poor. [ncbi.nlm.nih.gov]

The diagnosis of LS generally gets delayed as we look for other etiologies of patients presenting illness (thromboembolic event). [ncbi.nlm.nih.gov]

In this article Epidemiology History Examination Investigations Management Complications Prognosis Historical Libman-Sacks Endocarditis In this article Epidemiology History Examination Investigations Management Complications Prognosis Historical Synonyms [patient.info]

"Current Cancer Epidemiology". Journal of Epidemiology and Global Health. 9 (4): 217–222. doi:10.2991/jegh.k.191008.001. PMC 7310786. PMID 31854162. ^ a b Bender E (September 2014). "Epidemiology: The dominant malignancy". [en.wikipedia.org]

Epidemiologic, twin, and human leukocyte antigen data suggest a strong genetic contribution to the etiology of SLE, but the exact cause is unknown. [pedsinreview.aappublications.org]

In some cases, Libman–Sacks endocarditis may be the presenting pathology in systemic lupus erythematosus, especially in the presence of concurrent antiphospholipid syndrome.[4] Pathophysiology[edit] The initial cause of Libman–Sacks endocarditis is poorly [en.wikipedia.org]

In case of SLE with APLS, in which anticoagulation and antiplatelet therapy is required to prevent the thromboembolic event and thrombocytopenic purpura, after valve replacement, strict management of anticoagulation plays an essential role to prevent [jstage.jst.go.jp]

Rapidly find the answers you need with separate sections on diseases and disorders, differential diagnosis, clinical algorithms, laboratory results, and clinical preventive services, plus an at-a-glance format that uses cross-references, outlines, bullets [books.google.com]

Anticoagulation should be considered as secondary prevention for thromboembolic phenomena in patients who have had a thromboembolic event. [statpearls.com]

Anticoagulation merits consideration as secondary prevention for thromboembolic phenomena in patients who have had a thromboembolic event. [ncbi.nlm.nih.gov]