We describe a girl presenting with a childhood dermal mucinosis in which we had the unique opportunity to find all the transitional histological features of lichen myxoedematosus (papular mucinosis), from its early focal mucin deposition in the reticular [ncbi.nlm.nih.gov]

Of these reports presentation with plaques and nodule are rare. [ijdvl.com]

APPM is much more commonly seen in women and presents as white to flesh-coloured papules exclusively on the dorsal hands and extensor forearms. [casereports.bmj.com]

This review will describe the most recent classification on lichen myxedematosus in the generalized (scleromyxedema) and the localized forms, as well as the different organ systems involved in scleromyxedema, diagnostic workup, current management, and [ncbi.nlm.nih.gov]

• Hyperviscosity

  The pathophysiology is poorly understood, but monoclonal gamma paraproteinemia and blood hyperviscosity have been postulated as causes for this rare complication.17,18 Treatment is empirical, although IVIG has been used successfully in combination with [ncbi.nlm.nih.gov]

What is the treatment of lichen myxoedematosus? Treatment of scleromyxoedema is difficult and disappointing. [dermnetnz.org]

Treatment Options Treatment options for scleromyxedema are summarized in Table II. Table II. [dermatologyadvisor.com]

Medicalhistory revealed treatment of a psychological depressionby a variety of medications for about 20 years. [docslide.com.br]

APPM does not exhibit regression, and despite the benign course of the disease, patients frequently seek cosmetic treatment. [ncbi.nlm.nih.gov]

However, when myeloma is present, the patient generally has a poor prognosis. Scleromyxedema usually has a poorer prognosis than that of the other forms. [emedicine.medscape.com]

WITH PARAPROTEINEMIA Assosiated with: peripheral neuropathy, arhtropathy, carpel tunnel syndrome poor prognosis : Often due to Bronchopneumonia Coronary occlusion Hematologic abnormalities 12. [slideshare.net]

Lichen myxoedematosus is an unusual disorder of unknown etiology and pathogenesis. Although several treatments have reportedly been tried, therapeutic efficacies are variable and unsatisfactory. [ncbi.nlm.nih.gov]

Abstract References Citations Supplementary Data Article Media Metrics Suggestions Lichen myxoedematosus is an unusual disorder of unknown etiology and pathogenesis. [ingentaconnect.com]

A1 - VON ZEZSCHWITZ,K A, PY - 1959/1/1/pubmed PY - 1959/1/1/medline PY - 1959/1/1/entrez KW - LICHEN PLANUS/complications KW - MYXEDEMA/etiology and pathogenesis SP - 301 EP - 16 JF - Archiv fur klinische und experimentelle Dermatologie JO - Arch Klin [unboundmedicine.com]

DISCUSSION Scleromyxedema or lichen myxedematosus (LM) is a rare type of papular mucinosis, with a chronic and progressive course, chronic, progressive, of unknown etiology. [scielo.br]

Figure 4: M u c i n deposition dissecting the dermal collagen fibers (colloidal iron) DISCUSSION Scleromyxedema or lichen myxedematosus (LM) is a rare type of papular mucinosis, with a chronic and progressive course, chronic, progressive, of unknown etiology [docksci.com]

Epidemiology Race Persons of any race can be affected. Sex No sex-related predilection is reported. Age Most individuals with lichen myxedematosus are aged 30-70 years. [emedicine.medscape.com]

[…] referred to as lichen myxedematosus, papular mucinosis, or lichen fibromucinoidosis, the clinical circumstance of mucin deposited in the skin in the form of papules, nodules or plaques is now generally accepted as the cutaneous expression of the same pathophysiologic [annals.org]

Pathophysiology The etiology is unknown; however, the disease is commonly associated with plasma cell dyscrasia. The basic defect is hypothesized to be a fibroblast disorder, which causes the increased mucin deposition in the skin. [emedicine.medscape.com]

Etiology Pathophysiology The etiopathogenesis of scleromyxedema is unknown. The significance of the monoclonal gammopathy is a matter of debate. Paraprotein levels do not correlate with either the extent or the progression of the disease. [dermatologyadvisor.com]

Current medical research has not established a method of preventing the occurrence of Localized Lichen Myxedematosus with Monoclonal Gammopathy and/or Systemic Symptoms. [dovemed.com]

In this Article: Treating Symptoms with Home Remedies Treating Lichen Planus with Medical Care Preventing Outbreaks Community Q A 16 References. [sklxsp.ga]

[…] intralesionalinjections of hyaluronidase and triamcinolone, with littlesuccess.3,6 Surgical interventions using the carbondioxide laser for dermabrasion have been used to goodeffect, giving a moderate cosmetic improvement, but thistreatment does not prevent [documents.tips]

Recently it has been recently shown that FcRn is a protective receptor that prevents the catabolism of IgG. [ard.bmj.com]