Two Caucasian females aged 5 years and an 18-month male of north African descent presented with a membranous conjunctivitis, which recurred after surgical excision. [ncbi.nlm.nih.gov]

Clinical Presentation: The median age at diagnosis is about 5 years, and patients present with papillary white red lesions of firm consistency. Below is an image of lesions in both eyelids. [images.missionforvisionusa.org]

• Turkish

  In this report, a 1-month-old Turkish boy who had pseudomembranous conjunctivitis, occlusive hydrocephalus, and hydrocele is presented. [ncbi.nlm.nih.gov]

  […] of Turkish conflict of laws. [turkiyeklinikleri.com]

• Hodgkin Lymphoma

  We report a case of mucosal and skin deposits of an amyloid-like homogeneous material associated with non-Hodgkin's lymphoma and congenital auricular hypoplasia. [ncbi.nlm.nih.gov]

• Inspiratory Stridor

  After surgery for ventriculo-peritoneal shunt establishment, he developed inspiratory stridor, respiratory distress, and pulmonary atelectasis. Tracheal pseudomembranes were also demonstrated by bronchoscopy. [ncbi.nlm.nih.gov]

• Esotropia

  Case 2 was a 5-year-old patient with unilateral membranous conjunctivitis, esotropia, mechanical ptosis and complicated cataract, and had been treated with a number of medications. Histological investigation of the membrane in both cases showed LC. [ncbi.nlm.nih.gov]

  Upon examination, we found that she had right mechanical ptosis, esotropia, corneal leukoma, and complicated cataract, possibly steroid induced. [ijo.in]

• Conjunctival Disease

  Discussion Additional studies included corneal sensitivity testing, to rule out chronic conjunctival disease, and eyelid eversion, to rule out superior palpebral conjunctival involvement or scarring. [reviewofoptometry.com]

• Suggestibility

  We suggest a strategy for investigating known and new cases of ligneous conjunctivitis and/or pseudomembranous disease. [ncbi.nlm.nih.gov]

• Human Papillomavirus

  Because the patient had multiple papillomata of both hands, a possible association with human papillomavirus was suspected but never confirmed. [ncbi.nlm.nih.gov]

• Granulomatous Tissue

  Several times, granulomatous tissue was removed from the conjunctiva of the right eye but the result was recurrences at shorter intervals. Seven years after the onset in the right eye the left eye became affected. [ncbi.nlm.nih.gov]

Treatment with topical plasminogen resulted in prompt resolution of the membranes. Treatment with topical plasmin was ineffective. [ncbi.nlm.nih.gov]

Prognosis The visual prognosis is moderate. Corneal involvement may lead to blindness due to scarring, vascularisation, keratomalacia and perforation. The documents contained in this web site are presented for information purposes only. [orpha.net]

Prognosis The prognosis of ligneous conjunctivitis depends on the ability to control the inflammation and recurrence of the pseudomembranes. [eyewiki.aao.org]

The prognosis of ligneous conjunctivitis depends on the ability to control the inflammation and recurrence of the pseudomembranes. [eyewiki.org]

Prognosis: The prognosis for ligneous conjunctivitis is variable and is based upon the extent, length and the affected site producing symptoms. It depends on the ability to control inflammation and recurrence of pseudo-membranes. [nhp.gov.in]

With the knowledge of the etiology of ligneous conjunctivitis, efforts are underway to identify the best method of delivery of plasminogen. [ncbi.nlm.nih.gov]

Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10coded.com]

Etiology : Several mutations have been detected in the plasminogen gene of patients affected with ligneous conjunctivitis. [images.missionforvisionusa.org]

Summary Epidemiology Prevalence in the general population is unknown but estimates range between 0.13% and 0.42% in healthy subjects with heteterozygous hypoplasminogenemia. More than 200 cases have been reported so far. [orpha.net]

Definition / general Chronic relapsing pseudomembranous conjunctivitis with woody induration of eyelid and tarsal conjunctiva and pseudomembrane on tarsal conjunctiva Also affects other mucosa Epidemiology Usually children (median age 5 years), but can [pathologyoutlines.com]

Neurology and Neurosurgery Czech and Slovak Ophthalmology Czech and Slovak Psychiatry Czech Geriatric Review Czech Gynaecology Czech Rheumatology Czech Dental Journal Czech Urology Czech-Slovak Dermatology Czecho-Slovak Pathology Czech-Slovak Pediatrics Epidemiology [prolekare.cz]

Epidemiology Ligneous conjunctivitis is a rare disease that classically affects children, with a higher prevalence in females. 3 However, a review of the literature comprising 84 cases underlined that it is not only young girls who are affected. 4, 5 [entokey.com]

May 2005 Volume 46, Issue 13 Free ARVO Annual Meeting Abstract May 2005 Ligneous Conjunctivitis in an Adult Patient: A Study of Molecular Pathophysiology and Treatment Options Author Affiliations & Notes J. [iovs.arvojournals.org]

The pathophysiological mechanism is unclear at present. It is advisable to look for plasminogen deficiency in patients with congenital hydrocephalus, because obstruction of ventriculoperitoneal shunts is possible when such a condition is overlooked. [ncbi.nlm.nih.gov]

General Pathology The histology shows ulcerated conjunctiva with sub-epithelial, amyloid-like, eosinophilic material containing clotted fibrinogen and immunoglobulins, accompanied by lymphocytes, granulocytes, and plasma cells (Figure 1). [1] Pathophysiology [eyewiki.aao.org]

Although it responds well to steroid therapy, recurrence and relapse occur following the early reduction or withdrawal of medication. [2] As for the pathophysiologic correlation between LC and IgG4-RD, there is no literature available to illustrate the [ijo.in]

Prophylactic use of topical and subconjunctival fresh frozen plasma may help in the prevention of membranes in susceptible patients with plasminogen deficiency. [ncbi.nlm.nih.gov]