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Linear Atrophoderma of Moulin


  • We present a case of a young and healthy patient that developed such lesions on her upper and lower extremities over 5 years.[ncbi.nlm.nih.gov]
  • We present here a peculiar case of linear atrophoderma affecting a teenager.[moh-it.pure.elsevier.com]
  • It follows the line of Blaschko, and occurs without preceding inflammation, subsequent induration or scleroderma. The lesions usually develop during childhood or adolescence, and the prognosis is good.[ncbi.nlm.nih.gov]
  • We present a 40-year-old woman with asymptomatic, linear, hyperpigmented atrophic plaques in a Blaschkoid distribution on the right back and right upper extremity that is consistent with a diagnosis of linear atrophoderma of Moulin.[ncbi.nlm.nih.gov]
  • The lesions were asymptomatic and the child was otherwise healthy.[scinapse.io]
  • CASE REPORT A 22-year-old Malay woman presented with an 11-year history of asymptomatic, unilateral brown patches affecting the right arm, right side of the trunk, and right leg. There were no prior skin lesions or inflammation.[semanticscholar.org]
  • It is characterized by asymptomatic hyperpigmented atrophic band-like lesions localized mostly on the trunk following the lines of Blaschko. Distribution is usually unilateral, and extensive lesions with bilateral involvement are extremely rare.[papersearch.net]
  • Lipo-aspiration had previously been carried out in our departmentwith poor results.Due to the limitation of lipo-aspiration, the complexity of alternativesurgical procedures, and their recurrence rate, we decided to usein this patient laser lipolysis:[documents.tips]
  • […] site you agree to the terms outlined in our Cookies used here: Privacy / Disclaimer , Decide now: Start ROK II Current Leaders Krusten Krusten (14) Wizard Merlin (12) Hunter Thorin (12) Stacia Sapphire (8) KNtoran Wothfard (8) Anronrosby Cedrick (6) Aspiring[bordeglobal.com]
  • Minaga K, Kitano M, Enoki E, Kashida H, Kudo M: Needle-Tract Seeding on the Proximal Gastric Wall After EUS-Guided Fine-Needle Aspiration of a Pancreatic Mass. Am J Gastroenterology 111:1515, 2016.[med.kindai.ac.jp]
  • We present a case of a young and healthy patient that developed such lesions on her upper and lower extremities over 5 years.[ncbi.nlm.nih.gov]
  • Linear atrophoderma of moulin over face: An exceedingly rare entity. Indian J Dermatol 2017;62:214-5 How to cite this URL: Darung I, Rudra O, Samanta A, Agarwal M, Ghosh A. Linear atrophoderma of moulin over face: An exceedingly rare entity.[e-ijd.org]
  • Visualize more of the conditions you see in practice with over 3500 illustrations, of which over 1,400 are new: 1,039 clinical images, 398 pathology slides, and 152 schematics.[books.google.com]
  • 1 Inflamed bilateral linear atrophoderma of Moulin in an adult woman: a case report. ( 29589642 ) 2018 2 Linear atrophoderma of Moulin: A rare entity. ( 30106014 ) Kharkar VD...Mahajan SA 2018 3 Linear Atrophoderma of Moulin over Face: An Exceedingly[malacards.org]
  • It is characterized by atrophic bandlike skin lesions that often show hyperpigmentation and always follow the lines of Blaschko. Usually it begins in childhood or adolescence and there is no evidence of any long term progression.[ncbi.nlm.nih.gov]
  • Our data support the hypothesis that LAM had a history of inflammatory phase, which ultimately evolved into hyperpigmentation with atrophy (5).[docksci.com]
  • Firstly described by Moulin et al. in 1992 in 5 patients [1], LAM is a distinct clinical entity characterized by acquired atrophic bandlike skin lesions that often show hyperpigmentation and always follow the lines of Blaschko.[publicatt.unicatt.it]
Skin Atrophy
  • The swellinginitially developed after trauma 4 months before Evaluation of skin atrophy associated with linear atrophoderma of Moulin by ultrasound imaging References[dokument.tips]
  • Keywords : linear atrophoderma of moulin (1 items found) Atrophoderma of Moulin (1 items found) review (2982 items found) Linear dermatosiscalcipotriol treatment response priority journal Blaschko's lines histopathology skin atrophy skin disease case[info.rdi.ku.ac.th]
  • In the dermis, there was no distinct pigment incontinence, no inflammation or alteration of connective tissue texture, and the clinical impression of skin atrophy was attributed to atrophy of the subcutaneous tissue [ 1 ].[derm101.com]
  • atrophy associated with linear atrophoderma of Moulin by ultrasound imaging. ( 21679833 ) Norisugi O....Shimizu T. 2011 19 A teen-ager with linear atrophoderma of Moulin. ( 20178703 ) Schepis C....Lentini M. 2010 20 Lentiginosis within plaques of linear[malacards.org]
  • atrophy Localized abdominal wall skin atrophy Localized abdominal wall skin atrophy (disorder) Macular atrophy NSF - Nephrogenic fibrosing dermopathy Nephrogenic fibrosing dermopathy Nephrogenic systemic fibrosis Nephrogenic systemic fibrosis (disorder[averbis.com]
  • Pope FM, Narcisi P, Nicholls AC, Germaine D, Pals G, Richards AJ: COL3A1 mutations cause variable clinical phenotypes including acrogeria and vascular rupture. Br J Dermatol 1996;135:163–181.[karger.com]
  • The cited article by Utikalet al5 is remarkable because the authors discuss theLAM (COL3A1) gene as a possible causative factor.This gene has been shown to be defective in somecases of acrogeria/Ehlers-Danlos syndrome type IV.We should like to underline[docslide.fr]
Skin Discoloration
  • Division of Pediatric Dermatology Hackensack University Medical Center 2 Birthmarks and other skin discoloration Amount/location of melanin pigment 3 Origin and destinations of melanocytes from the neural crest Explains CNS, ocular, and auditory findings[healthdocbox.com]
Short Arm
  • Ballabio A, Andria G: Deletions and translocations involving the distal short arm of the human X-chromosome: Review and hypotheses. Hum Mol Genet 1992;1:221–227.[karger.com]


  • "Scleroderma Workup" . Medscape Reference . WebMD . Retrieved 6 March 2014 . Jimenez, SA; Cronin, PM; Koenig, AS; O'Brien, MS; Castro, SV (15 February 2012). Varga, J; Talavera, F; Goldberg, E; Mechaber, AJ; Diamond, HS, eds.[ipfs.io]
Lymphocytic Infiltrate
  • Although the patient's overall clinical picture supports a diagnosis of LAM with hyperpigmented, depressed lesions following the lines of Blaschko and perivascular lymphocytic infiltrate on biopsy, the bilateral presentation typical of APP, collagen entrapment[ncbi.nlm.nih.gov]
  • The first skin biopsy from a hyperpigmented patch over the right arm found mild upper dermal perivascular lymphocytic infiltrate. No dermal sclerosis was seen.[mafiadoc.com]
  • In the papillary dermis proliferation of superficial vessels with mild lymphocytic infiltrate and melanin-laden macrophages were present. The collagen fibres and elastic fibres were normal.[jdcr.eu]


  • Due to its relationship to idiopathic atrophoderma of Pierini-Pasini and linear scleroderma, treatment with intravenous penicillin was tried. In our case it had no effect.[ncbi.nlm.nih.gov]
  • No previous reports have discussed the treatment of LAM. This case is reported to discuss the use of methotrexate as an effective treatment of this rare skin condition.[docksci.com]


  • The lesions usually develop during childhood or adolescence, and the prognosis is good. The diagnosis is made clinically and histopathologically.[ncbi.nlm.nih.gov]


  • LAM is an etiologically unknown form of dermal atrophy. It is generally characterized by oval or round atrophic, nonsclerotic, hyperpigmented patches following Blaschko's lines.[ncbi.nlm.nih.gov]
  • The exact etiology of LAM is still obscure. Several treatment modalities were reported but none was consistently successful. We report a case of LAM in which a favorable outcome was obtained with topical calcipotriol.[info.rdi.ku.ac.th]
  • Classification of these conditions often presents many nosological challenges, since underlying etiologies and pathogenetics are often not known.[howlingpixel.com]
  • […] role in diagnosing localized scleroderma.Br J Dermatol 2003;148:724-9.doi:10.1016/j.jaad.2009.12.005Retiform hemangioendothelioma treated withMohs micrographic surgeryTo the Editor: Retiform hemangioendothelioma is alow grade angiosarcoma of unknown etiology[dokument.tips]


  • “The epidemiology of morphea (localized scleroderma) in Olmsted County 1960-1993”. J. Rheumatol. 24 (1): 73–80. PMID 9002014. Laxer RM, Zulian F (2006). “Localized scleroderma”.[thetanningguru.com]
  • Juvenile localized scleroderma: clinical and epidemiological features in 750 children. An international study. Rheumatology (Oxford).[wikidoc.org]
  • "Epidemiology of systemic sclerosis: incidence, prevalence, survival, risk factors, malignancy, and environmental triggers.". Current Opinion in Rheumatology . 24 (2): 165–70. doi : 10.1097/BOR.0b013e32834ff2e8 .[ipfs.io]
  • Epidemiology, clinical presentation, and pathogenesis”. J Am Acad Dermatol. vol. 64. 2011. pp. 217-28. (This is a comprehensive review of morphea that highlights the different classifications of morphea that include APP.[clinicaladvisor.com]
  • Epidemiology, clinical presentation, and pathogenesis". J Am Acad Dermatol. vol. 64. 2011. pp. 217-28. (This is a comprehensive review of morphea that highlights the different classifications of morphea that include APP.[dermatologyadvisor.com]
Sex distribution
Age distribution


  • To date, the pathophysiology is unclear. Different authors hypothesize that the disease is secondary to a mosaic manifestation as a result of a post-zygotic mutational event.[ncbi.nlm.nih.gov]
  • Other possible factors involved in the pathophysiology include hemodynamic disturbances, neural alteration, angiogenic factors, and changes in supportive connective tissue and vasculature.[dermatologyadvisor.com]
  • Endothelin signalling is implicated in the pathophysiology of fibrosis. [19] Vitamin D is implicated in the pathophysiology of the disease.[ipfs.io]


  • The information presented here is not intended to diagnose, treat, cure or prevent any disease. Read disclaimer.[gulfdoctor.net]
  • Your skin Holds body fluids in, preventing dehydration Keeps harmful microbes out, preventing infections Helps you feel things like heat, cold, and pain Keeps your body temperature even Makes vitamin D when the sun shines on it Anything that irritates[icdlist.com]
  • Skin inflammation was confirmed as the cause of alopecia when topical aspirin cured the inflammation and prevented the hair loss .[reizendeaardeschool.nl]
  • Analgesia (painkillers) and anti-inflammatory drugs, including steroids, are used to suppress the symptoms, while disease-modifying antirheumatic drugs (DMARDs) are required to inhibit or halt the underlying immune process and prevent long-term damage[kriso.ee]

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