We present a case of a young and healthy patient that developed such lesions on her upper and lower extremities over 5 years. [ncbi.nlm.nih.gov]

We present here a peculiar case of linear atrophoderma affecting a teenager. [moh-it.pure.elsevier.com]

We present a 17-year-old girl with multiple asymptomatic brownish atrophic plaques in a zosteriform distribution on the left side of the trunk. Clinical presentation and dermatopathology was compatible with the diagnosis of linear atrophoderma. [scinapse.io]

Case presentation A 17-year-old girl presented with a six-month history of multiple asymptomatic brownish atrophic plaques in a zosteriform distribution on the left side of her trunk ( Figure 1 ). [derm101.com]

The information presented here is not intended to diagnose, treat, cure or prevent any disease. Read disclaimer. [gulfdoctor.net]

• Inflammation

  It follows the line of Blaschko, and occurs without preceding inflammation, subsequent induration or scleroderma. The lesions usually develop during childhood or adolescence, and the prognosis is good. [ncbi.nlm.nih.gov]

  Role of PPARgamma in inflammation. Prospects for ... Skin inflammation was confirmed as the cause of alopecia when topical aspirin cured the inflammation and prevented the hair loss. [reizendeaardeschool.nl]

• Asymptomatic

  We present a 40-year-old woman with asymptomatic, linear, hyperpigmented atrophic plaques in a Blaschkoid distribution on the right back and right upper extremity that is consistent with a diagnosis of linear atrophoderma of Moulin. [ncbi.nlm.nih.gov]

  The lesions were asymptomatic and the child was otherwise healthy. [scinapse.io]

  It is characterized by asymptomatic hyperpigmented atrophic band-like lesions localized mostly on the trunk following the lines of Blaschko. Distribution is usually unilateral, and extensive lesions with bilateral involvement are extremely rare. [papersearch.net]

  CASE REPORT A 22-year-old Malay woman presented with an 11-year history of asymptomatic, unilateral brown patches affecting the right arm, right side of the trunk, and right leg. There were no prior skin lesions or inflammation. [semanticscholar.org]

• Congestive Heart Failure

  […] rate and fainting due to conduction abnormalities, hypertension and congestive heart failure. [ipfs.io]

• Overeating

  Linear atrophoderma of moulin over face: An exceedingly rare entity. Indian J Dermatol 2017;62:214-5 How to cite this URL: Darung I, Rudra O, Samanta A, Agarwal M, Ghosh A. Linear atrophoderma of moulin over face: An exceedingly rare entity. [e-ijd.org]

  We present a case of a young and healthy patient that developed such lesions on her upper and lower extremities over 5 years. [ncbi.nlm.nih.gov]

  Blaschko’s lines follow a V-shape over the upper spine, an S-shape over the abdomen, an inverted U-shape from the breast to the upper arm, and perpendicular lines up and down the arms and legs. [aocd.org]

  1 Inflamed bilateral linear atrophoderma of Moulin in an adult woman: a case report. ( 29589642 ) 2018 2 Linear atrophoderma of Moulin: A rare entity. ( 30106014 ) Kharkar VD...Mahajan SA 2018 3 Linear Atrophoderma of Moulin over Face: An Exceedingly [malacards.org]

• Hyperpigmentation

  Our data support the hypothesis that LAM had a history of inflammatory phase, which ultimately evolved into hyperpigmentation with atrophy (5). [docksci.com]

  Firstly described by Moulin et al. in 1992 in 5 patients [1], LAM is a distinct clinical entity characterized by acquired atrophic bandlike skin lesions that often show hyperpigmentation and always follow the lines of Blaschko. [publicatt.unicatt.it]

  They also proposed the terms 'Diffuse LWNH' for previous reported cases of LWNH and 'Localized-form' for PCZH. [4] Also known as zebra-like hyperpigmentation in whorls and streaks, reticulate and zosteriform hyperpigmentation, reticulate hyperpigmentation [idoj.in]

  It is characterized by atrophic bandlike skin lesions that often show hyperpigmentation and always follow the lines of Blaschko. Usually it begins in childhood or adolescence and there is no evidence of any long term progression. [ncbi.nlm.nih.gov]

  Histopathologic examination revealed irregular and moderate hyperpigmentation of the lower part of the epidermis with few perivascular lymphocytes in the dermis. The collagen bundles and the elastic fibers are unchanged. [papersearch.net]

• Skin Lesion

  The diagnosis is clinical, characterized by acquired unilateral hyperpigmented, depressed band-like skin lesions following Blaschko's lines. [ncbi.nlm.nih.gov]

  In our patient, we noted the coexistence of pigmented and erythematous areas on linear distributed skin lesions of LAM. [docksci.com]

• Skin Atrophy

  |Atrophy of skin caused by systemic corticosteroid|Atrophy of skin caused by systemic corticosteroid (disorder)|Atrophy of skin caused by topical corticosteroid|Atrophy of skin caused by topical corticosteroid (disorder)|Atrophy of skin due to systemic [averbis.com]

  The swellinginitially developed after trauma 4 months before Evaluation of skin atrophy associated with linear atrophoderma of Moulin by ultrasound imaging References [dokument.tips]

  Keywords : linear atrophoderma of moulin (1 items found) | Atrophoderma of Moulin (1 items found) | review (2982 items found) | Linear dermatosiscalcipotriol | treatment response | priority journal | Blaschko's lines | histopathology | skin atrophy | [info.rdi.ku.ac.th]

  In the dermis, there was no distinct pigment incontinence, no inflammation or alteration of connective tissue texture, and the clinical impression of skin atrophy was attributed to atrophy of the subcutaneous tissue [ 1 ]. [derm101.com]

  atrophy associated with linear atrophoderma of Moulin by ultrasound imaging. ( 21679833 ) Norisugi O....Shimizu T. 2011 19 A teen-ager with linear atrophoderma of Moulin. ( 20178703 ) Schepis C....Lentini M. 2010 20 Lentiginosis within plaques of linear [malacards.org]

• Acrogeria

  Pope FM, Narcisi P, Nicholls AC, Germaine D, Pals G, Richards AJ: COL3A1 mutations cause variable clinical phenotypes including acrogeria and vascular rupture. Br J Dermatol 1996;135:163–181. [karger.com]

  The cited article by Utikalet al5 is remarkable because the authors discuss theLAM (COL3A1) gene as a possible causative factor.This gene has been shown to be defective in somecases of acrogeria/Ehlers-Danlos syndrome type IV.We should like to underline [docslide.fr]

• Short Arm

  Ballabio A, Andria G: Deletions and translocations involving the distal short arm of the human X-chromosome: Review and hypotheses. Hum Mol Genet 1992;1:221–227. [karger.com]

• Incontinence

  Histopathologically, a moderate diffuse hyperpigmentation within the lower epidermis, a focal vacuolar degeneration of the basal layer, and a few dermal perivascular lymphocytes accompanied by signs of pigment incontinence were noted. [ncbi.nlm.nih.gov]

  In the dermis, there was no distinct pigment incontinence, no inflammation or alteration of connective tissue texture, and the clinical impression of skin atrophy was attributed to atrophy of the subcutaneous tissue [ 1 ]. [derm101.com]

  […] streaks of macular hyperpigmentation following Blaschko lines; no preceding vesicles, bullae or inflammation; no sex predilection; sparing of mucous membranes, eyes, palms and soles; and histologically by epidermal melanosis without dermal pigmentary incontinence [idoj.in]

  Linear atrophoderma of Moulin: a case report and review of ... was no distinct pigment incontinence, no inflammation or alteration of connective tissue texture, and the clinical ... [reizendeaardeschool.nl]

  Mar 11th, 2018 - The use of energy-based devices for the treatment of vaginal laxity, orgasmic dysfunction, and stress incontinence, such as minimally ablative fractional laser and radiofrequency, is gaining momentum. [allmedx.com]

"Scleroderma Workup". Medscape Reference. WebMD. Retrieved 6 March 2014. ↑ Jimenez, SA; Cronin, PM; Koenig, AS; O'Brien, MS; Castro, SV (15 February 2012). Varga, J; Talavera, F; Goldberg, E; Mechaber, AJ; Diamond, HS, eds. [ipfs.io]

• Lymphocytic Infiltrate

  Although the patient's overall clinical picture supports a diagnosis of LAM with hyperpigmented, depressed lesions following the lines of Blaschko and perivascular lymphocytic infiltrate on biopsy, the bilateral presentation typical of APP, collagen entrapment [ncbi.nlm.nih.gov]

  The first skin biopsy from a hyperpigmented patch over the right arm found mild upper dermal perivascular lymphocytic infiltrate. No dermal sclerosis was seen. [mafiadoc.com]

  In the papillary dermis proliferation of superficial vessels with mild lymphocytic infiltrate and melanin-laden macrophages were present. The collagen fibres and elastic fibres were normal. [jdcr.eu]

Currently, there is no standard treatment regimen for LAM. [ncbi.nlm.nih.gov]

No previous reports have discussed the treatment of LAM. This case is reported to discuss the use of methotrexate as an effective treatment of this rare skin condition. [docksci.com]

The lesions usually develop during childhood or adolescence, and the prognosis is good. The diagnosis is made clinically and histopathologically. [ncbi.nlm.nih.gov]

LAM is an etiologically unknown form of dermal atrophy. It is generally characterized by oval or round atrophic, nonsclerotic, hyperpigmented patches following Blaschko's lines. [ncbi.nlm.nih.gov]

Classification of these conditions often presents many nosological challenges, since underlying etiologies and pathogenetics are often not known. [howlingpixel.com]

The exact etiology of LAM is still obscure. Several treatment modalities were reported but none was consistently successful. We report a case of LAM in which a favorable outcome was obtained with topical calcipotriol. [info.rdi.ku.ac.th]

Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis Pascal 002 Biological and medical sciences / 002B Medical sciences / 002B08 Dermatology / 002B08J Skin involvement in other diseases. [pascal-francis.inist.fr]

“The epidemiology of morphea (localized scleroderma) in Olmsted County 1960-1993”. J. Rheumatol. 24 (1): 73–80. PMID 9002014. ^ Laxer RM, Zulian F (2006). “Localized scleroderma”. [thetanningguru.com]

Juvenile localized scleroderma: clinical and epidemiological features in 750 children. An international study. Rheumatology (Oxford). [wikidoc.org]

"Epidemiology of systemic sclerosis: incidence, prevalence, survival, risk factors, malignancy, and environmental triggers.". Current Opinion in Rheumatology. 24 (2): 165–70. doi : 10.1097/BOR.0b013e32834ff2e8. [ipfs.io]

Epidemiology, clinical presentation, and pathogenesis”. J Am Acad Dermatol. vol. 64. 2011. pp. 217-28. (This is a comprehensive review of morphea that highlights the different classifications of morphea that include APP. [clinicaladvisor.com]

Epidemiology, clinical presentation, and pathogenesis". J Am Acad Dermatol. vol. 64. 2011. pp. 217-28. (This is a comprehensive review of morphea that highlights the different classifications of morphea that include APP. [dermatologyadvisor.com]

To date, the pathophysiology is unclear. Different authors hypothesize that the disease is secondary to a mosaic manifestation as a result of a post-zygotic mutational event. [ncbi.nlm.nih.gov]

Other possible factors involved in the pathophysiology include hemodynamic disturbances, neural alteration, angiogenic factors, and changes in supportive connective tissue and vasculature. [dermatologyadvisor.com]

Endothelin signalling is implicated in the pathophysiology of fibrosis. [19] Vitamin D is implicated in the pathophysiology of the disease. [ipfs.io]

The information presented here is not intended to diagnose, treat, cure or prevent any disease. Read disclaimer. [gulfdoctor.net]

Your skin Holds body fluids in, preventing dehydration Keeps harmful microbes out, preventing infections Helps you feel things like heat, cold, and pain Keeps your body temperature even Makes vitamin D when the sun shines on it Anything that irritates [icdlist.com]

Analgesia (painkillers) and anti-inflammatory drugs, including steroids, are used to suppress the symptoms, while disease-modifying antirheumatic drugs (DMARDs) are required to inhibit or halt the underlying immune process and prevent long-term damage [kriso.ee]

Skin inflammation was confirmed as the cause of alopecia when topical aspirin cured the inflammation and prevented the hair loss. [reizendeaardeschool.nl]