Pain was evaluated with a 10-item questionnaire, a pain rating scale (PRS), and the Wong-Baker Faces scale. Treatment resulted in a significant reduction of pain with a decrease in mean scores of all three measures. [ncbi.nlm.nih.gov]

Pain in affected areas likely Pain in affected areas No pain initially No pain Pain is likely Affected population: Best estimate is 11% adult women (study done in Germany) Unknown; best estimate is a few percent of adult women Low 30% of US adults 30% [en.wikipedia.org]

After years of weight gain, pain, and swelling, you're finally diagnosed with lipedema – a common but "enigmatic" disease of the peripheral fat. [news-medical.net]

Although weight loss may not help, prevention of additional weight gain is important, as any weight gain to the affected body areas becomes difficult to treat. Emotional support is often overlooked. [journals.sagepub.com]

In each group, the results were dismal as leg swelling worsened or was unchanged in greater than 90% whereas symptoms such as heaviness, fatigue, cramps (termed varicogenic symptomatology) were improved in less than 10%. [ncbi.nlm.nih.gov]

Keywords: lipedema, leg swelling, lipodystrophy, localized adiposity, lower extremity liposuction This work is published and licensed by Dove Medical Press Limited. [dx.doi.org]

Symptoms include painful legs and symmetrical leg swelling ending abruptly just above the ankles, known as the ‘cut-off sign’, as seen in Figure 1. [journals.sagepub.com]

Brautigam, P., Foldi, E., Schaiper, I., Krause, T., Vanscheidt, W., and Moser, E. (1998) Analysis of lymphatic drainage in various forms of leg edema using two compartment lymphoscinctigraphy. Lymphology 31, 43-55 20. [lipomadoc.org]

Clinical use of indirect lymphography in different forms of leg edema. Lymphology 1988;21:152160. 16. Tiedjen KU, Schultz-Ehrenburg U. Holzmann H, Altmeyer P, Hör G. Isotopenlymphographische Befunde beim Lipödem. [journals.lww.com]

Abstract Lipedema is a chronic vascular disease almost exclusively of female sex, characterized by the deposit of fat on the legs, with an "Egyptian column" shape, orthostatic edema, hypothermia of the skin, alteration of the plantar support, and negativity [ncbi.nlm.nih.gov]

Areas affected: Buttocks, legs, thighs, arms Areas not affected: Hands, feet, upper torso Pain: Present with pressure Pitting edema: No Stemmer’s sign: No Orthostatic edema: Present, particularly in warmer months Other signs: Fat pad at medial ankle, hypothermia [consultqd.clevelandclinic.org]

Karen Herbst, an international expert in lipedema and other fat disorders has also added the following criteria: Hypothermia of the involved skin Involvement of the upper extremities/arms in 30% of patients Worsened swelling with orthostasis in the summer [prsinstitute.wustl.edu]

[…] issues that can accompany Lipedema and I have listed some of them here: pain and tenderness on pressure, uncontrollable weight gain, venous insufficiency, lymphedema, hypermobility, cellulitis, digestive issues, numbness, joint pain, painful lipomas, hypothermia [gofundme.com]

Decongestive therapy resulted in a significant reduction of the number of petechiae while no change was detected within the control group. [ncbi.nlm.nih.gov]

Upon examination, petechiae were noted in both lower extremities and a lipoma was observed under the right knee joint ( Fig. 1, 2 ). [dx.doi.org]

Side effects can include pain, bruising, and petechiae (broken blood vessels). [lymphaticnetwork.org]

According to studies, decongestive treatments significantly reduce capillary fragility and the number of petechiae, as well as the mean limb volume in patients with lipedema[33]. [parjournal.net]

Microscopically, there are dermal and septal edema, adipocyte degeneration, and numerous mast cells, features held in common with lipedematous alopecia. [ncbi.nlm.nih.gov]

This is usually bilateral (affects both sides) and symmetrical (occurs evenly) The feeling of fatty ‘nodules’ underneath the skin Bruising occurs easily and is often unexplained Legs are sensitive to touch Deep throbbing pain in legs, pain in knee joints [allthingsholistic.net]

*Horse chestnut capsules relieve leg pain and swelling. *Bio-rutin improves circulation and keeps capillaries open. It also stops the bruising and bleeding so common with lipedema. *Cayenne Pepper will also stop the bleeding caused by lipedema. [alignlife.com]

Lipedema Other names Lipoedema, lipödem, lipalgia, adiposalgia, adipoalgesia, adiposis dolorosa, lipomatosis dolorosa of the legs, lipohypertrophy dolorosa, painful column leg, painful lipedema syndrome A very advanced case of lipedema of the right leg [en.wikipedia.org]

Symptoms: Symptoms vary significantly by person, not all people have all symptoms : - Symmetrical presentation, involving both legs - Pain in soft tissues at rest, and upon walking or when touched; hypersensitivity to touch - Accumulation of lipedemic [tawfiksefriouimd.com]

Yet there are many telltale symptoms, including: Fat deposits on the legs, thighs and buttocks. Painful legs. Swelling that doesn’t indent if you apply pressure to it (called non-pitting edema). [health.clevelandclinic.org]

The pre/post-treatment VAS mean score changes were: heaviness from 4.57 3.46 to 2.43 2.57 (-47%), dysesthesias from 1.71 2.63 to 0.71 1.50 (-58%), pain from 1.57 2.57 to 0.57 0.79 (-64%). [ncbi.nlm.nih.gov]

Key signs and symptoms include: • feeling of heaviness in the legs (aching dysesthesia) • easy bruising • sensitivity to touch (called “painful fat syndrome”) • orthostatic edema • oatmeal-like changes to skin texture. [woundcareadvisor.com]

The patient was a 45-year-old woman with chronic back pain, worsening bilateral L5 radiculopathy, and degenerative disc disease. [ncbi.nlm.nih.gov]