Since the intercellular canalicular system present between the tumor cells was continuous with the "peripheral canalicular system," both systems probably have a common function related to steroid metabolism. [ncbi.nlm.nih.gov]

The cut surfaces are typically yellow or orange if large amounts of lipid are present, red to brown if the cells are lipid-poor or dark brown to black if large quantities of cytoplasmic lipochrome pigment are present. [ijpmonline.org]

In this report, we present a rare case of a mesenteric steroid cell tumor. Case presentation A 31-year-old Asian woman presented in our institute with a history of pelvic mass. [jmedicalcasereports.biomedcentral.com]

Herein, we present a case of a 28-year-old female with NOS subtype of steroid cell tumor, who presented with hirsutism, virilization, and amenorrhea and a had successful response to surgery during follow-up. [edm.bioscientifica.com]

• Adnexal Mass

  A CT scan confirmed a 10.4 5.9 cm solid left adnexal mass as well as another solid nodule mass measuring 4.9 × 4 cm in the cul-de-sac and mild ascites (Figures 1(c) and 1(d)). [hindawi.com]

• Ovarian Disorder

  Young and Scully´s 1979 classification of ovarian tumors with endocrine manifestations ( Figure 1 ) includes sex-cord stromal tumors, steroid-cell tumors and other ovarian disorders with endocrine function. [omicsonline.org]

Tumor markers such as CA-125, CEA, and CA 19-9 are typically not helpful in the workup. [hindawi.com]

• Ovarian Mass

  Imaging including CT of the adrenals and ovaries can identify an ovarian or adrenal mass. There have been reports of small aberrant masses in the parametria that can go missed on imaging. [hindawi.com]

Prompt diagnosis and treatment are emphasized in this potentially malignant and disfiguring androgenic tumor that is readily amenable to surgery. [ncbi.nlm.nih.gov]

Salvage therapy Patients with failed primary treatment are offered salvage treatment protocols (e.g. TIP, GPT) and in some cases high dose intensity multi drug treatment. Salvage treatment is with curative intent. [bccancer.bc.ca]

The primary treatment is surgical extirpation of the primary lesion and there are no reports of effective treatment with radiation or chemotherapy. [ijpmonline.org]

Statistics and Prognosis Granulosa cell tumors occur at the peak age of 50-55, but can occur earlier in life. They are known to reappear as much as a decade or two after one is diagnosed. [knowcancer.com]

The prognosis of SCT is usually good and correlates with the stage and degree of differentiation of the tumor [ 3 ]. [ispub.com]

or therapies New developments in treatment As with any cancer, prognosis and long-term survival can vary greatly from individual to individual. [stanfordchildrens.org]

The prognosis is similar to that of the latter tumor. [glowm.com]

Prognosis of these germ cell tumors is excellent. [intechopen.com]

Register Malignant Lipid Cell Tumor of the Ovary: Clinical, Biochemical and Etiologic Considerations - 24 Hours access EUR €36.00 GBP £28.00 USD $45.00 Rental This article is also available for rental through DeepDyve. [academic.oup.com]

Malignant lipid cell tumor of the ovary: clinical, biochemical and etiologic considerations. J Clin Endocrinol Metab. 1970 Mar;30(3):336–344. [PubMed] [Google Scholar] Taylor HB, Norris HJ. Lipid cell tumors of the ovary. [ncbi.nlm.nih.gov]

Lipsett MB, Kirschner MA, et al (1970) Malignant lipid-cell tumor of the ovary: Clinical, biochemical and etiologic considerations. J Clin Endocrinol 30:336–344 Google Scholar 11. [link.springer.com]

Etiology The exact etiology of dysgerminomas is not identified, though recent molecular studies have implicated loss of function with potential tumor suppressor gene TRC8/RNF139 as a possible etiology [48]. [intechopen.com]

Discussion In a case of rapid-onset hirsutism, virilization, and menstrual irregularity, neoplastic etiology should always be kept in mind. Therefore, comprehensive workup is required. [edm.bioscientifica.com]

Ovarian Cancer, a volume in the American Cancer Society Atlas of Clinical Oncology series, thoroughly discusses pathology, biology, epidemiology, genetics and screening. [books.google.de]

Sertoli–Leydig cell tumor group Epidemiology Sertoli-Leydig cell tumors are uncommon benign tumors, accounting for less than 0.5% of all ovarian tumors. [emedicine.medscape.com]

Epidemiology They are the second most common% ) hepatic adenoma, after the inf. Adenoma; Carcinoma. [kunoyofymuxy.tk]

Hepatocellular Carcinoma: Epidemiology, Risk Factors, and Screening. Medscape, from Semin Liver Dis. 2005;25(2):143-154 [On-line information]. Available online at http://www.medscape.com/viewarticle/506830. (2005 January 05). LBA AFP-L3. [labtestsonline.hu]

Epidemiology studies have shown a correlation between increased risk of ovarian epithelial tumours with increased number of ovulation cycles. [atlasgeneticsoncology.org]

Furuya M (2012) Ovarian cancer stroma: pathophysiology and the roles in cancer development. Cancers (Basel) 4: 701-724. Roth LM, Talerman A (2006) Recent advances in the pathology and classification of ovarian germ cell tumors. [omicsonline.org]

Pathophysiology Historically, most theories of the pathophysiology of ovarian cancer included the concept that it begins with the dedifferentiation of the cells overlying the ovary. [emedicine.medscape.com]

Pathophysiology: Two theories exist as to the etiology of sex cord騯tromal tumors. The first proposes that these neoplasms are derived from the mesenchyme of the developing genital ridge. [www1.cgmh.org.tw]

[…] though research is still ongoing in this area.[24] Higher caffeine intake and consumption of more than two cups of tea a day have both been associated with lower ovarian cancer risk.[21] Smoking tobacco is protective for sex cord-stromal tumors.[22] Pathophysiology [en.wikipedia.org]

[…] aren’t many ways to prevent GCT, although it is possible to detect it early. [knowcancer.com]

Preventive Services Task Force Reaffirmation Recommendation Statement. USPSTF [On-line information].Available online at http://www.uspreventiveservicestaskforce.org/uspstf12/ovarian/ovarartaddend.htm.Accessed October 2012. [labtestsonline.it]

Is it possible to prevent ovarian cancer? There is no way to truly prevent ovarian cancer. [medicinenet.com]

Mechanism of action is through binding to guanine thereby preventing DNA transcription. [www1.cgmh.org.tw]