The authors present a case of a 35-year-old Myanmarese man with a sclerosing lipogranuloma of the penis due to injection of mineral oil successfully managed with penile biopsy and excision with split-thickness skin graft phalloplasty and provide a review [scholars.northwestern.edu]

We aimed with this presentation to keep in mind this benign lesion and also to assist the algorithmic approach. [ncbi.nlm.nih.gov]

• Surgical Procedure

  The lesion should be recognized as a benign process for which biopsy is the only feasible surgical procedure. These masses are thought to be the result of degenerative and mild chronic inflammatory changes in the fat. [typeset.io]

  Sometimes, post-surgical infection could occur as well Warm compresses to the affected eyelid, administration of corticosteroid injections, or minor surgical procedures are used to treat a Chalazion; although, in many cases, the condition is self-limiting [dovemed.com]

  Although ESS is generally a safe surgical procedure, complications can occasionally occur, especially in the orbit due to the close proximity of the paranasal sinus. [ajnr.org]

• Turkish

  English Arabic German English Spanish French Hebrew Italian Japanese Korean Dutch Polish Portuguese Romanian Russian Swedish Turkish Ukrainian Chinese Show more (Greek, Hindi, Thai, Czech...) [context.reverso.net]

  Turkish Journal of Rheumatology. 2014 Sep 1;29(3):228. Akbulut M, Utku Y, Soysal S. Lipogranuloma of the cervix in a postmenopausal patient with a uterine prolapse. Arch Gynecol Obstetr. 2008;277(3):277-9. Sasidaran R, Zain MA, Basiron NH. [ijord.com]

• Subcutaneous Nodule

  Lipogranuloma commonly manifests clinically as palpable lymphadenopathy and subcutaneous nodules. [ibimapublishing.com]

  Lipogranuloma commonly manifests clinically as palpable lymphadenopathy and subcutaneous nodules or can involve other components of reticuloendothelial system (bone marrow, liver, spleen). [1] Being rare, lipogranulomas have been reported in penis, nasal [ijpmonline.org]

  Patients experience painful erections and penile deformity and usually have tender subcutaneous nodules from penile base, along its shaft and in the scortum. [tandfonline.com]

  Reports on the development of subcutaneous nodules at the sites of injection abound – commonly referred to as sclerosing lipogranuloma (SL) and paraffinoma (6). [medicaljournals.se]

  Clinically, periorbital and orbital lipogranuloma commonly manifests as a palpable subcutaneous nodule, eyelid swelling, or even proptosis[8]. Currently there are only four published reports of lipogranuloma with orbital involvement[9]–[10]. [ncbi.nlm.nih.gov]

• Headache

  Occasionally, headache and fever might occur A progressively growing Chalazion may place adverse pressure on the eye ball, or even cause a temporary disruption in vision. [dovemed.com]

METHODS: Clinical history, ocular workup, and CT were performed. Histopathologic examination was performed after eyelid tissue excision. [ncbi.nlm.nih.gov]

Progress logically from the histologic pattern, through the appropriate workup, around the pitfalls, to the best diagnosis. [books.google.com]

Lymphoma workup was negative, with no evidence of B cell rearrangement by kappa light chain PCR, nor presence of clonal lymphocyte population. Figure 1. Hematoxalin and Eosin, 4x. [ibimapublishing.com]

Her hematological workup revealed a marked normochromic normocytic anemia and high ESR. There was no evidence of leukocytosis or lymphocytosis. Blood and urine culture showed negative growth. [ijpmonline.org]

Further workup for confirmation is usually not necessary except in recurrent cases where sebaceous gland carcinoma needs to be excluded. [eyewiki.aao.org]

• Granulomatous Tissue

  The masses are composed of granulomatous tissue formed around an either exogenous or endogenous lipomatous substance. We describe a 47-year-old male patient who presented with a growing, painless scrotal mass on physical examination. [ncbi.nlm.nih.gov]

  The masses are composed of granulomatous tissue formed around an either exogenous or endogenous lipomatous substance. In case of incomplete resection the masses show a rapid recurrence, thus mimicking a neoplastic lesion. [springerlink.com]

  Introduction Lipogranuloma or sclerosing lipogranuloma is an unusual benign granulomatous reaction to exogenous or endogenous lipids.(1,2) Although this benign process may involve various organs, there has only been one report of axillary localization [archivesofrheumatology.org]

Surgical excision with penile reconstruction is the mainstay of treatment. [scholars.northwestern.edu]

Objective treatment outcomes after intralesional triamcinolone injection and/or oral prednisolone were evaluated by measuring the size of the lipogranulomas pre- and post-treatment. [ncbi.nlm.nih.gov]

Treatment and Outcome of Vaseline-Induced Sclerosing Lipogranuloma of the Penis. [hungary.pure.elsevier.com]

The prognosis of Chalazion is usually excellent with adequate treatment Please find comprehensive information on Chalazion regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis [dovemed.com]

Because of the long duration and the absence of acute local symptoms, this syndrome can be considered benign with favorable prognosis, but the physician should know it. top of page [minervamedica.it]

The prognosis is usually good following treatment with steroids. Similar articles [Pseudotumors of the orbit and their relationship to granulomatous inflammation]. Kaufman OIa, Khoroshilova IP, Zakharova GP. Kaufman OIa, et al. [pubmed.ncbi.nlm.nih.gov]

Prognosis Excellent prognosis is expected. Untreated chalazion can resolve spontaneously in weeks. Boyd K, Pagan-Duran B. Chalazia and Stye. American Academy of Ophthalmology. [eyewiki.aao.org]

[…] are somewhat different, as the accumulations in Erdheim-Chester disease are hypointense 3 brain: usually the hypothalamus 3 ; intraparenchymal masses in ECD appear nonspecific 10 pituitary infundibulum: presenting with diabetes insipidus Treatment and prognosis [radiopaedia.org]

Primary sclerosing lipogranuloma of the scrotum, therefore, is a peculiar inflammation characterized by granulomas consisting of monocytes and marked tissue eosinophilia of unknown etiology. [ncbi.nlm.nih.gov]

Endogenous etiology elicits lipid degeneration from an allergic/inflammatory mechanism as a result of severe heat/cold and/or trauma. Lipogranuloma via endogenous etiology is noted to be a more rare occurrence. [ibimapublishing.com]

The illustrations are supported by a concise, up-to-date text that describes etiology, pathology, clinical manifestations, laboratory tests, and treatment options for the individual diseases. [books.google.com]

Epidemiology Rare; most patients are young adults Sites Usually affects penis, scrotum, spermatic cord and perineum Etiology Usually due to injection or topical application of oil based substances (paraffin, silicone, oil or wax) for cosmetic or therapeutic [pathologyoutlines.com]

Epidemiology Rare; most patients are young adults Sites Usually affects penis, scrotum, spermatic cord and perineum Etiology Usually due to injection or topical application of oil based substances (paraffin, silicone, oil or wax) for cosmetic or therapeutic [pathologyoutlines.com]

Foreign body granulomas after the use of dermal fillers: pathophysiology, clinical appearance, histologic features, and treatment. Arch Plast Surg. 2015;42(2):232-9. doi:10.5999/aps.2015.42.2.232 Issue Section Case Report How to Cite 1. [jsurgmed.com]

Pathophysiology Meibomian glands are sebaceous glands located in the tarsal plate of eyelid. [eyewiki.aao.org]

The pathophysiology of lipogranuloma has been described via two different mechanisms, exogenous and endogenous. [ibimapublishing.com]

OBJECTIVES: The authors aimed to report 5 cases of patients with penile lipogranuloma-induced full necrosis of penile skin, wherein they obtained good results from simultaneous implementation of Y-V incision to prevent the shortening of penile length [ncbi.nlm.nih.gov]

The meibomian gland (also known as the tarsal gland) supplies oil or sebum that prevents the eye film from drying-up While some Chalazia may be tiny, most may often be visible as lumps on the eyelid. [dovemed.com]

This was attributed to the antibiotic ointment vehicle that coated the petroleum jelly-impregnated gauze placed intranasally to prevent epistaxis. Postoperatively, all four patients had an encapsulated cystic mass within 3 weeks. [journals.healio.com]

Affiliations PMID: 8858639 Case Reports Lipogranuloma: a preventable complication of dacryocystorhinostomy J Kerendian et al. Ophthalmic Surg Lasers. 1996 Aug. [pubmed.ncbi.nlm.nih.gov]