The authors present 2 cases of LPG with apo E3/3 genotyping associated with psoriasis vulgaris. [ncbi.nlm.nih.gov]

Herein, the authors present the first described case of LPG in a Brazilian male patient, 11 years, who presented with a steroid-resistant nephrotic syndrome. Renal function was normal. [scielo.br]

• Hypertensive Retinopathy

  Malignant hypertension was defined as severe elevation of mean arterial pressure in combination with grade III to IV hypertensive retinopathy, according to the Keith-Wagener and Barker classification. [bmcnephrol.biomedcentral.com]

Progress logically from the histologic pattern, through the appropriate workup, around the pitfalls, to the best diagnosis. [books.google.de]

Laboratory workup showed the features of a nephrotic syndrome, with normal urine sediment and oval fat bodies (detailed data on Table 1). Workup for underlying infectious disease was negative. [scielo.br]

• Fibrinoid Necrosis

  Reduction of NO and activation of a coagulation cascade leads to fibrinoid necrosis, edema of arterioles and local platelet aggregation. [bmcnephrol.biomedcentral.com]

  Focal cellular crescents were seen in only 2 (13%) cases, while fibrinoid necrosis was not seen in any case. Twelve (80%) cases showed interstitial inflammation, which was predominantly focal. [academic.oup.com]

• Ischemic Changes

  The other six moderately-enlarged glomeruli showed extensive ischemic changes, retraction of the glomerular tuft and marked thickening and wrinkling of the capillary wall (Figure 1 A,B,C). [bmcnephrol.biomedcentral.com]

A successful treatment for LPG has not yet been established. [ncbi.nlm.nih.gov]

Each treatment session consisted of 10 cycles, and a total of 3 000 ml plasma was regenerated. One treatment course consisted of 10 treatment sessions, and a total of 30 l plasma was regenerated. [academic.oup.com]

[…] for the treatment of hypertension. [jmedicalcasereports.biomedcentral.com]

The renal outcome as well as the prognosis of this disease is worse than other forms of RPGN such as those from microscopic polyangiitis. Therefore, early therapeutic intervention is essential to improve its prognosis. [medworm.com]

In addition, the tests give directions to improve your prognosis. ● Blood Urine Location Tests: to find out where the blood cells from, glomeruli or urinary tract; the severity of blood urine; to offer direction for the drug use. ● Heart Function Tests [aadilhospital.com]

Treatment and Prognosis Treatment with fenofibrate and irbesartan was initiated. Two weeks later, serum triglycerides and urinary protein excretion were reduced to 200 mg/dL and 1 g/g Cre, respectively. [karger.com]

Comparison of types I and II in children and adults and long-term prognosis. Am J Med. 1983 Feb. 74(2):175-92. [Medline]. O'Shaughnessy MM, Montez-Rath ME, Lafayette RA, Winkelmayer WC. [emedicine.medscape.com]

The virus-mediated transduction of apoE Sendai resulting in the development of LPG in apoE-deficient mice confirms the etiologic role of apoE mutation in LPG. [ncbi.nlm.nih.gov]

Recently, effective therapy with intensive lipid-lowering agents was established, and epidemiologic data are required for early diagnosis. [ncbi.nlm.nih.gov]

Familial renal amyloidosis due to Apolipoprotein AII variant Synonym(s): - LPG Classification (Orphanet): - Inborn errors of metabolism - Rare endocrine disease - Rare genetic disease - Rare renal disease Classification (ICD10): (no data available) Epidemiological [csbg.cnb.csic.es]

Renal AA amyloidosis: survey of epidemiologic and laboratory data from one nephrology centre. ----Int Urol Nephrol. 2009 Dec;41(4):941-5. Cuchard P1, Cuchard R, Rotman S, Burnier M, Gauthier T. Renal amyloidosis. [wwjournals.com]

Epidemiologic and clinical studies to assess the contribution of novel HDL metrics to cardiovascular disease and stroke risk prediction. [ohsu.edu]

To clarify the pathophysiologic role of this mutation, we investigated the binding and the uptake of apoE3' triglyceride-rich lipoproteins to human umbilical vein endothelial cells (HUVEC). [ncbi.nlm.nih.gov]

New chapters on common issues regarding prescribing in kidney disease, palliative nephrology, endemic nephropathies, pathophysiology of chronic kidney disease, and outcomes of dialysis. [books.google.it]

The pathophysiological effect of this mutation was investigated in vitro by binding studies of recombinant apo E2 Kyoto to LDL receptors on human fibroblasts. [uniprot.org]

On the other hand, the administration of fibrate with the intensive control of triglyceride and apolipoprotein E particularly from the early phase will ameliorate LPG and prevent renal dysfunction. [ncbi.nlm.nih.gov]

Although there have been considerable advances in the management of renal failure by dialysis and transplantation, there has been relatively little progress in its prevention. [books.google.es]

The Center for Preventive Cardiology at the Knight Cardiovascular Institute aims to reduce the burden of cardiovascular disease through prevention, early detection, and tailored treatment. [ohsu.edu]

Early treatment with lipid-lowering agents is important to prevent the development of renal failure. [jstage.jst.go.jp]

The following three topics were the focus of the three-day program: I) The molecular approach to studying risk factors and prevention 2) The creation of novel animal models 3) Lipoprotein disorder as a cause of activation of vascular endothelial cells [books.google.de]