Presentation
The authors present 2 cases of LPG with apo E3/3 genotyping associated with psoriasis vulgaris. [ncbi.nlm.nih.gov]
Entire Body System
- Congestive Heart Failure
The liquid is initially concentrated in the ankles but it subsequently becomes generalized and is called anasarca. [34] Patients with congestive heart failure also experience an abnormal swelling of the heart cardiomegaly, which aids in making a correct [en.wikipedia.org]
Respiratoric
- Cough
• Recurrent cough, cold, infections • Chronic high blood pressure • Weakness of the arm, legs, face, or other areas • Reduced urine and frequent urination at night • Chest pain • Dizziness and headache • Protein in urine, blood in urine • Back pain [aadilhospital.com]
Cardiovascular
- Heart Failure
This phenomenon may lead to heart failure. This issue explores in depth the relationship between glucolipotoxicity and heart failure. Vista previa del libro » [books.google.es]
failure due to pericarditis or myocarditis, liver dysfunction measured on at least 2 separate occasion) Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the [clinicaltrials.gov]
Studies to understand the contribution of factors secreted by the epicardial adipose depot to heart disease and heart failure. [ohsu.edu]
● Heart Function Tests: It includes Accu Troponin and NT-proBNP. Accu Troponin > 14pg/ml, it indicates myocardial damage; Accu Troponin > 100pg/ml, it indicates myocardial infarction; Elevated NT-proBNP level marks heart failure. [aadilhospital.com]
heart failure can cause liquid retention in tissues as a consequence of the decrease in the strength of ventricular contractions. [en.wikipedia.org]
- Chest Pain
• Recurrent cough, cold, infections • Chronic high blood pressure • Weakness of the arm, legs, face, or other areas • Reduced urine and frequent urination at night • Chest pain • Dizziness and headache • Protein in urine, blood in urine • Back pain [aadilhospital.com]
Ikizler 2018 reported seven study‐related adverse events with six of those happening in the aerobic exercise and caloric restriction group (atrial fibrillation requiring hospitalisation (1), hypotension due to weight loss (2), chest pain during exercise [cochranelibrary.com]
Musculoskeletal
- Arthritis
Guidance News;2005-15 4 Wu Yan-hong, He Xi-nan, Ma Xiao-lu, Pang Xue-feng, Liu Huan, Huang Ren-fa, Meng Yu-hua; Clinical Observation of the Treatment of Systemic Lupus with Severe Thrombocytopenia by Double Filtration Plasmapheresis [J];Rheumatism and Arthritis [en.cnki.com.cn]
Remission of proteinuria and preservation of renal function in patients with renal AA amyloidosis secondary to rheumatoid arthritis. [wwjournals.com]
Clinical Medicine Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders about the journal submit your research Indexing: ESCI, DOAJ, EBSCO, PubMed Central (PMC) and more. [insights.sagepub.com]
[…] basement membrane, nodules within glomeruli ( Kimmelstiel-Wilson nodules ) Treatment of underlying disease Amyloidosis May also involve other tissues (e.g., heart ) Can be associated with multiple myeloma or chronic inflammatory disease (e.g., rheumatoid arthritis [amboss.com]
Renin Mutations and Autosomal Dominant Tubulointerstitial Kidney Disease Renin Secreting Tumors (Juxtaglomerular Cell Tumor) Reset Osmostat Retrocaval Ureter Retroperitoneal Fibrosis Rhabdomyolysis, Rhabdomyolysis related to Bariatric Sugery Rheumatoid Arthritis-Associated [kidney.nyc]
- Back Pain
• Recurrent cough, cold, infections • Chronic high blood pressure • Weakness of the arm, legs, face, or other areas • Reduced urine and frequent urination at night • Chest pain • Dizziness and headache • Protein in urine, blood in urine • Back pain [aadilhospital.com]
Psychiatrical
- Withdrawn
Venous blood samples were withdrawn after an overnight fast of 12-14 hours and sera were separated and stored at -70°C till analysis. Lp (a) levels were measured using enzyme linked immunosorbent assay (Immuno-Diagnostics, USA). [jpma.org.pk]
Neurologic
- Headache
In February 2009, she had a severe headache and blurry vision and presented at a local hospital with severe hypertension. Blood pressure was 220/160 mmHg. [ncbi.nlm.nih.gov]
Just two months before admission (February 2009), she felt a severe headache, blurry vision, nausea, vomiting, and presented to a local hospital. [bmcnephrol.biomedcentral.com]
Case report A 16-year-old man presented with a 7-day history of headache. Direct questioning revealed a 1-month history of tiredness, breathlessness on exertion, ankle oedema, and blurred vision. There was no relevant past medical history. [mafiadoc.com]
• Recurrent cough, cold, infections • Chronic high blood pressure • Weakness of the arm, legs, face, or other areas • Reduced urine and frequent urination at night • Chest pain • Dizziness and headache • Protein in urine, blood in urine • Back pain [aadilhospital.com]
It is a poorly understood condition with symptoms such as high blood pressure, proteinuria, and headaches, potentially even leading to seizures. The treatment opti... [medworm.com]
- Confusion
• Change in mental status, such as restlessness, sleepiness, fatigue, confusion, decreased ability to concentrate etc. • Recurrent cough, cold, infections • Chronic high blood pressure • Weakness of the arm, legs, face, or other areas • Reduced urine [aadilhospital.com]
Membranoproliferative glomerulonephritis and C3 glomerulopathy: resolving the confusion. Kidney Int. 2012 Mar. 81(5):434-41. [Medline]. Nargund P, Kambham N, Mehta K, Lafayette RA. [emedicine.medscape.com]
- Dizziness
• Recurrent cough, cold, infections • Chronic high blood pressure • Weakness of the arm, legs, face, or other areas • Reduced urine and frequent urination at night • Chest pain • Dizziness and headache • Protein in urine, blood in urine • Back pain [aadilhospital.com]
- Seizure
It is a poorly understood condition with symptoms such as high blood pressure, proteinuria, and headaches, potentially even leading to seizures. The treatment opti... [medworm.com]
Urogenital
- Kidney Failure
Format Definition Uncommon kidney disease characterized by proteinuria, progressive kidney failure, and distinctive lipoprotein thrombi in glomerular capillaries. [uniprot.org]
Get Update Overview Lipoprotein glomerulopathy is an uncommon kidney disease characterized by proteinuria, progressive kidney failure, and distinctive lipoprotein thrombi in glomerular capillaries ({5:Saito et al., 2006}). [diseaseinfosearch.org]
About Me Conditions and Treatments kidney disease, glomerular disease, polycystic kidney disease, kidney transplant, kidney failure, high blood pressure disorder, glomerulonephritis, hemodialysis, kidney stone, peritoneal dialysis Credentials Positions [nyulangone.org]
Joshua Schwimmer A List of Kidney Diseases Abderhalden–Kaufmann–Lignac syndrome (Nephropathic Cystinosis) Abdominal Compartment Syndrome Acetaminophen-induced Nephrotoxicity Acute Kidney Failure/Acute Kidney Injury Acute Lobar Nephronia Acute Phosphate [kidney.nyc]
Dialysis Dialysis is suggested when hypertensive nephropathy develops kidney failure in which the kidneys cannot work properly to remove the toxins in the blood. Dialysis works to filter the small sized toxins out of the blood. [aadilhospital.com]
Workup
Progress logically from the histologic pattern, through the appropriate workup, around the pitfalls, to the best diagnosis. [books.google.de]
Laboratory workup showed the features of a nephrotic syndrome, with normal urine sediment and oval fat bodies (detailed data on Table 1 ). Workup for underlying infectious disease was negative. [scielo.br]
Serum
- Hyperglycemia
Accelemted atherogenesis in diabetic patients may be due to increased frequency of dyslipidemia, hyperglycemia. obesity, hypertension and associated nephropathy 4. [jpma.org.pk]
Treatment
A successful treatment for LPG has not yet been established. [ncbi.nlm.nih.gov]
Therefore, early biopsy, effective treatment (fibrate-containing treatment), and adequate control of blood pressure are important to improving the outcome of LPG. [bmcnephrol.biomedcentral.com]
Each treatment session consisted of 10 cycles, and a total of 3 000 ml plasma was regenerated. One treatment course consisted of 10 treatment sessions, and a total of 30 l plasma was regenerated. [academic.oup.com]
Prognosis
The renal outcome as well as the prognosis of this disease is worse than other forms of RPGN such as those from microscopic polyangiitis. Therefore, early therapeutic intervention is essential to improve its prognosis. [medworm.com]
In addition, the tests give directions to improve your prognosis. ● Blood Urine Location Tests: to find out where the blood cells from, glomeruli or urinary tract; the severity of blood urine; to offer direction for the drug use. ● Heart Function Tests [aadilhospital.com]
Comparison of types I and II in children and adults and long-term prognosis. Am J Med. 1983 Feb. 74(2):175-92. [Medline]. O'Shaughnessy MM, Montez-Rath ME, Lafayette RA, Winkelmayer WC. [emedicine.medscape.com]
Prognosis [ edit ] The prognosis for nephrotic syndrome under treatment is generally good although this depends on the underlying cause, the age of the patient and their response to treatment. [en.wikipedia.org]
Etiology
TERMINOLOGY Abbreviations Lipoprotein glomerulopathy (LPG) Definitions Glomerular disease characterized by glomerular capillary lipoprotein thrombi, proteinuria, and progressive renal failure ETIOLOGY/PATHOGENESIS Genetics Mutation in APOE gene Encodes [basicmedicalkey.com]
The virus-mediated transduction of apoE Sendai resulting in the development of LPG in apoE-deficient mice confirms the etiologic role of apoE mutation in LPG. [ncbi.nlm.nih.gov]
Epidemiology
Recently, effective therapy with intensive lipid-lowering agents was established, and epidemiologic data are required for early diagnosis. [ncbi.nlm.nih.gov]
Familial renal amyloidosis due to Apolipoprotein AII variant Synonym(s): - LPG Classification (Orphanet): - Inborn errors of metabolism - Rare endocrine disease - Rare genetic disease - Rare renal disease Classification (ICD10): (no data available) Epidemiological [csbg.cnb.csic.es]
Renal AA amyloidosis: survey of epidemiologic and laboratory data from one nephrology centre. ----Int Urol Nephrol. 2009 Dec;41(4):941-5. Cuchard P1, Cuchard R, Rotman S, Burnier M, Gauthier T. Renal amyloidosis. [wwjournals.com]
Epidemiologic and clinical studies to assess the contribution of novel HDL metrics to cardiovascular disease and stroke risk prediction. [ohsu.edu]
Pathophysiology
To clarify the pathophysiologic role of this mutation, we investigated the binding and the uptake of apoE3' triglyceride-rich lipoproteins to human umbilical vein endothelial cells (HUVEC). [ncbi.nlm.nih.gov]
New chapters on common issues regarding prescribing in kidney disease, palliative nephrology, endemic nephropathies, pathophysiology of chronic kidney disease, and outcomes of dialysis. [books.google.it]
The pathophysiological effect of this mutation was investigated in vitro by binding studies of recombinant apo E2 Kyoto to LDL receptors on human fibroblasts. [uniprot.org]
Prevention
On the other hand, the administration of fibrate with the intensive control of triglyceride and apolipoprotein E particularly from the early phase will ameliorate LPG and prevent renal dysfunction. [ncbi.nlm.nih.gov]
Although there have been considerable advances in the management of renal failure by dialysis and transplantation, there has been relatively little progress in its prevention. [books.google.es]
The Center for Preventive Cardiology at the Knight Cardiovascular Institute aims to reduce the burden of cardiovascular disease through prevention, early detection, and tailored treatment. [ohsu.edu]
The following three topics were the focus of the three-day program: I) The molecular approach to studying risk factors and prevention 2) The creation of novel animal models 3) Lipoprotein disorder as a cause of activation of vascular endothelial cells [books.google.de]
Proximal tubules and epithelial cells of the kidney prevent the loss of these proteins in the urine by reabsorbing them from the urinary filtrates. [bhj.org.in]