The patients were aged 53, 51 and 56 years and presented 4, 7 and 90 months post-transplant, respectively. [ncbi.nlm.nih.gov]

Symptoms were present for > 4 days prior to presentation in 8 (27%) patients. [ahcmedia.com]

In 19 (63%) of 30 patients, symptoms were present for >24 h; in 8 (27%), symptoms were present for ⩾4 days. [cid.oxfordjournals.org]

• Fever

  Abstract A 65-year-old man with primary haemochromatosis was admitted because of fever and confusion. He was found to have bacteraemia and meningitis due to Listeria monocytogenes. [ncbi.nlm.nih.gov]

  Intravenous ampicillin improved the symptoms of fever, bloody diarrhea, and headache without any neurological sequelae. [jstage.jst.go.jp]

  Persisting fever was defined as a body temperature of ⩾38°C for >10 days after the start of appropriate antimicrobial treatment. Recurrent fever was defined as fever reoccurring after at least 1 afebrile day. [cid.oxfordjournals.org]

• Chills

  The patient had followed Department of Health advice to immunocompromised patients and had avoided soft cheeses, cook-chill meals, and salads. He had, however, recently eaten paté produced in Belgium. [ncbi.nlm.nih.gov]

  Symptoms caused by this organism can be similar to flu and include high temperature, muscle ache or pain, chills, feeling or being sick and diarrhoea. [metro.co.uk]

  Chill : Make sure that your fridge is at 5°C or below. Put chilled food in the fridge straight away and eat it as soon as possible. Throw out food that has passed the ‘use by’ or the ‘best before’ date. [safefood.eu]

  Tests uncovered Listeria monocytogenes, which can cause high temperature, muscle ache or pain, chills, feeling or being sick and diarrhoea. However, in rare cases, the infection can be more severe, causing serious complications, such as meningitis. [mirror.co.uk]

  You can get it from lots of types of food, but it's mainly a problem with chilled, ready-to-eat foods, such as: cooked sliced meats and cured meats smoked fish and cooked shellfish blue veined and mould-ripened soft cheeses, like camembert and brie pâté [nhs.uk]

• High Fever

  A 90-year-old woman presented with high fever, nausea, diarrhea, and incontinence of urination and feces. Lumbar puncture was performed. [ncbi.nlm.nih.gov]

  Read more: Meningitis » The hallmark symptoms of bacterial meningitis are: high fever stiff neck severe headache If you develop the disease, you may also experience: nausea vomiting sensitivity to bright light confusion a rash of purple discoloration [healthline.com]

  Symptoms and Signs Primary listerial bacteremia is rare and causes high fever without localizing symptoms and signs. Endocarditis, peritonitis, osteomyelitis, septic arthritis, cholecystitis, and pleuropneumonia may occur. [merckmanuals.com]

  Symptoms High fever, headache, and stiff neck are common symptoms in anyone over the age of 2 years. These symptoms can develop over several hours, or they may take 1 to 2 days. [pritzkerlaw.com]

• Malaise

  She had been unwell with fever and malaise for 3 days. On examination, her temperature was 39.1°C, pulse rate was 90 per minute and blood pressure 150/90 mm Hg. She was alert with no signs of meningism. [pn.bmj.com]

  Fever and malaise Clinical features during admission Embolism No Yes No No Heart failure Yes Yes No No Kidney failure Yes No No No Persistent infection b No No No No Septic shock No No No No Vegetation diameter, mm 4,7 7 12 5,4 Periannular complication [revespcardiol.org]

  […] renal failure) immunosuppression (e.g. functional asplenia, splenectomy, hypogammaglobulinemia, complement deficiency, steroids, diabetes mellitus) malnutrition low socioeconomic status and overcrowding exposure to epidemic CLINICAL FEATURES History malaise [lifeinthefastlane.com]

  On day 12, he developed a fever, night sweats, chills, dyspnea and general malaise. [ncbi.nlm.nih.gov]

• Rigor

  Journal of Probiotics & Health is one of the top leading journals in biomedical engineering which publishes novel research articles after rigorous peer-review process by at least 2 expert reviewers of the associated fields. [omicsonline.org]

  The fever was intermittent, high grade, not associated with chills and rigors, was occurring daily and used to normalize with antipyretic medications. The headache was continuous, holocranial, throbbing and was associated with nausea and vomiting. [neurologyindia.com]

• Severe Clinical Course

  Despite of our patient had no such data, the disease had severe clinical course with the both of purulent meningoencephalitis and sepsis. [aclr.com.es]

• Vomiting

  Call your doctor immediately if your child develops fast or labored breathing, a fever, loss of appetite, vomiting, dehydration, a high-pitched cry, excessive sleepiness, or irritability. [kidshealth.org]

  Primary clinical picture manifests as intestinal infection - diarrhea, nausea and vomiting [ 2 ]. [aclr.com.es]

  Other symptoms may include nausea, vomiting, discomfort looking into bright lights, confusion, and sleepiness. [pritzkerlaw.com]

• Nausea

  A 90-year-old woman presented with high fever, nausea, diarrhea, and incontinence of urination and feces. Lumbar puncture was performed. [ncbi.nlm.nih.gov]

  Primary clinical picture manifests as intestinal infection - diarrhea, nausea and vomiting [ 2 ]. [aclr.com.es]

  Other symptoms include high temperatures, muscle aches, chills, nausea and diarrhoea. The now-recalled sandwich meat has a use-by date of February 21. The FSA said: ‘If you have bought the above product, do not eat it. [metro.co.uk]

  Encephalitis caused by Listeria are often misdiagnosed initially due a nonspecific prodromal (fever, headache, nausea and vomiting) and unusual meningeal signs 1-3. [radiopaedia.org]

  […] the sudden onset of fever, chills, severe headache, vomiting, and other influenza-type symptoms. [18, 28] Along these same lines, the CDC notes that infected individuals may develop fever, muscle aches, and sometimes gastrointestinal symptoms such as nausea [about-listeria.com]

• Tachycardia

  On physical examination, he had lethargy and acutely ill with a high fever (temperature 38℃), tachycardia and meningeal signs. [ncbi.nlm.nih.gov]

• Photophobia

  There are often other symptoms, such as Nausea Vomiting Photophobia (increased sensitivity to light) Altered mental status (confusion) In newborns and babies, the meningitis symptoms of fever, headache, and neck stiffness may be absent or difficult to [cdc.gov]

• Diplopia

  However she noticed diplopia due to left 6th nerve paresis, which resolved over in one-week. On the 12 th day, her CRP was reduced to 2.3 mg/L and ESR came down to 23 mm/1 hour. [esciencecentral.org]

  A brain MRI was performed because of a suspected increase in the intracranial pressure and the development of diplopia; there were no clinical findings suggestive of brain edema, such as an increase in the size of the ventricles. [ncbi.nlm.nih.gov]

• Headache

  Intravenous ampicillin improved the symptoms of fever, bloody diarrhea, and headache without any neurological sequelae. [jstage.jst.go.jp]

  Clinical manifestations include FEVER, altered mentation, HEADACHE, meningeal signs, focal neurologic signs, and SEIZURES. (From Medicine 1998 Sep;77(5):313-36) [ http://www.ebi.ac.uk/ontology/webulous#OPPL_pattern ] Synonyms: Meningitis, Listeria [ebi.ac.uk]

  We report a 60-year-old immunocompetent woman who presented with progressively intermittent headache for 3 weeks. Brain magnetic resonance imaging revealed leptomeningeal enhancement on T1-weighted imaging. [tzuchi.com.tw]

  […] infection, the resulting illness is either mild or quite severe, in what is sometimes referred to as a “bimodal distribution of severity.” [13, 28] On the mild end of the spectrum, listeriosis usually consists of the sudden onset of fever, chills, severe headache [about-listeria.com]

• Seizure

  Symptoms including confusion, seizures, pain and paralysis may be a result of either metastases to the nervous system or one of several nonmetastatic complications of cancer. [books.google.ro]

  Clinical manifestations include FEVER, altered mentation, HEADACHE, meningeal signs, focal neurologic signs, and SEIZURES. (From Medicine 1998 Sep;77(5):313-36) [ http://www.ebi.ac.uk/ontology/webulous#OPPL_pattern ] Synonyms: Meningitis, Listeria [ebi.ac.uk]

  For example, seizures are often more frequent. It can be a long road to being able to walk and communicate well again. [pritzkerlaw.com]

  Patients with impairment of consciousness, neurological deficits, or seizures, underwent cranial computed tomography (CT) before lumbar puncture. [bmcinfectdis.biomedcentral.com]

• Neck Stiffness

  After 5 days, he developed an impaired consciousness, headache, and neck stiffness. A sample of the colonic mucosa, blood cultures, and cerebrospinal fluid revealed Listeria monocytogenes infection. [jstage.jst.go.jp]

  The prevalence of the classic triad of fever, neck stiffness, and altered mental status was 43%, and almost all patients presented with at least 2 of the 4 classic symptoms of headache, fever, neck stiffness, and altered mental status. [cid.oxfordjournals.org]

• Confusion

  Abstract A 65-year-old man with primary haemochromatosis was admitted because of fever and confusion. He was found to have bacteraemia and meningitis due to Listeria monocytogenes. [ncbi.nlm.nih.gov]

  Symptoms including confusion, seizures, pain and paralysis may be a result of either metastases to the nervous system or one of several nonmetastatic complications of cancer. [books.google.ro]

  Symptoms of a Listeria infection can take up to 70 days to develop and include fever, headache, muscle aches, upset stomach, diarrhea, stiff neck, loss of balance, and confusion. [foodpoisoningbulletin.com]

  Read more: Meningitis » The hallmark symptoms of bacterial meningitis are: high fever stiff neck severe headache If you develop the disease, you may also experience: nausea vomiting sensitivity to bright light confusion a rash of purple discoloration [healthline.com]

  Listeria (liss-TEER-ee-uh) infections can cause symptoms such as: fever muscle aches vomiting or diarrhea stiff neck confusion weakness Pregnant women with an infection may only have mild flu-like symptoms, like muscle aches, but are at risk for premature [kidshealth.org]

• Irritability

  […] infection in the blood). [3, 18] Early-onset listeriosis is most often acquired through trans-placental transmission. [18, 24] Late-onset neonatal listeriosis is less common than the early-onset form. [4, 18, 24] Clinical symptoms may be subtle and include irritability [about-listeria.com]

  […] stiff neck severe headache If you develop the disease, you may also experience: nausea vomiting sensitivity to bright light confusion a rash of purple discoloration Parents of babies and toddlers under the age of 2 should closely monitor any lingering irritability [healthline.com]

  His mother then took him to an emergency department, where he was found to be irritable, tachycardic, and febrile to 39.2°C. No other abnormal examination findings were identified. [jcm.asm.org]

  Call your doctor immediately if your child develops fast or labored breathing, a fever, loss of appetite, vomiting, dehydration, a high-pitched cry, excessive sleepiness, or irritability. [kidshealth.org]

• Hyponatremia

  Hyponatremia was defined as a plasma sodium concentration 18, 19 ]. [cid.oxfordjournals.org]

• Hyperglycemia

  There were no major side-effects of dexamethasone therapy (gastro-intestinal bleeding, hyperglycemia). The overall mortality was 28% (12 of 43 patients) and five of thirty-one (16.1%) surviving patients had a neurological deficit at discharge. [bmcinfectdis.biomedcentral.com]

• Monocytosis

  However emergence of opportunistic infections such as mycobacteria, listeria monocytosis, nocardiosis, and invasive aspergilosis raised safety concerns. [esciencecentral.org]

• Listeria Monocytogenes

  We present a case of a previously healthy 7-year-old boy who developed Listeria monocytogenes meningitis. [ncbi.nlm.nih.gov]

  Inflammatory lesions were associated with the presence of Listeria monocytogenes, as demonstrated by a positive anti-Listeria monocytogenes immunoperoxidase reaction within phagocytic cells. [visavet.es]

  Foods contaminated with Listeria monocytogenes can cause outbreaks of meningitis. Meningitis caused by Listeria monocytogenes bacteria occurs most often in newborns, older adults, and people with long-term illnesses or impaired immune systems. [wa.kaiserpermanente.org]

• Gram-Positive Rods

  Gram positive rod Beta hemolytic Catalase positive Motile at 25 degree centigrade (tumbling motility/umbrella motility) Non-spore forming rod Susceptible hosts Newborns Elderly Immunocompromised. [meddean.luc.edu]

  An early presumptive diagnosis of Listeria infection may be possible with close attention to preliminary reports of Gram-positive rods. [neoreviews.aappublications.org]

  Gram stain showed pleomorphic short gram positive rods and coccobacilli, which exhibited a characteristic tumbling motility in hanging drop preparation. [ijmm.org]

  positive rods = Listeria MANAGEMENT Empiric Treatment antibiotics within 30 min of initial assessment dexamethasone 0.15mg/kg Q6 hourly with or before the first dose of antibiotics ceftriaxone (immunocompetent) or vancomycin + ciprofloxacin/moxifloxacin [lifeinthefastlane.com]

  Light microscopic findings show gram positive cocco-rods that were documented as Listeria monocytogenes in the CSF culture (×1,000, Gram stain, Thioglycollate broth culture of CSF). [ncbi.nlm.nih.gov]

• Gram-Positive Bacteria

  SLE patients who had a cerebrospinal fluid (CSF) culture positive for L. monocytogenes or other gram-positive bacteria were included. All patients fulfilled at least 4 ACR criteria for SLE. [acrabstracts.org]

  High degree of alert is essential among clinicians and microbiologists whenever gram variable or Gram-positive bacteria are noticed on Gram-stain. References 1. Swaminathan B, Gerner-Smidt P. The epidemiology of human listeriosis. [ijhas.in]

  Gram-staining resulted negative. On day 3, a real-time polymerase chain reaction (RT-PCR) for viruses and bacteria was positive for L. monocytogenes. [ijponline.biomedcentral.com]

  However, it allows only a retrospective diagnosis for listeriosis and lacks specificity, since a false-positive result can be due to cross-reactions with hemolysins from other Gram-positive bacteria. [jcm.asm.org]

• Leukocytosis

  Most children, including our patient, presented with leukocytosis with neutrophilia and with elevated CRP. [ijponline.biomedcentral.com]

Ampicillin with or without an aminoglycoside remains the best treatment for listeriosis. [ncbi.nlm.nih.gov]

Early diagnosis and adequate treatment are therefore essential to achieve the best outcome. [ijponline.biomedcentral.com]

1 Listeria Meningitis during Infliximab-based Treatment for Ulcerative Colitis. ( 29607962 ) Tsuchiya A....Terai S. 2018 2 Complications of Listeria meningitis in two immunocompetent children. ( 29878630 ) Shimbo A....Shimohira M. 2018 3 The right diagnosis [malacards.org]

MRI T1 : hypo to isointense lesion T2/FLAIR : hyperintense DWI : hyperintense/hypointense on ADC map T1 C+ : linear cranial nerve enhancement ring enhancement (abscess) heterogeneous if extensive inflammation Treatment and prognosis It is reported to [radiopaedia.org]

What is the outlook (prognosis)? Most cases of listeriosis in healthy adults and children are mild and only last for a short time with full recovery. Infection in babies often has a poor outlook. [patient.info]

We also review literature reports of this condition in post-neonatal immunocompetent children, published in English since 1996, in order to discuss its clinical presentation, diagnosis, treatment options and prognosis. [ijponline.biomedcentral.com]

The meningitis caused by L. monocytogenes differs from other types of bacterial meningitis, especially in treatment and prognosis. L. monocytogenes meningitis has been mostly reported at the extremes of life. [scielo.br]

Although some cases of other etiologies were also reported, this report informs those who manage patients with meningitis that not only Mycobacterium and Brucella spp. but also other facultative agents can increase ADA levels in cerebrospinal fluid, possibly [ncbi.nlm.nih.gov]

Since the etiologic importance of this organism can therefore be easily overlooked, it seems desirable to record one additional case. CASE REPORT The patient was a 62 year old woman whose past FULL TEXT [annals.org]

Etiology Listeria monocytogenes is an anaerobic and gram-positive bacillus. [radiopaedia.org]

It was an unusual etiological agent in immunocompetent patients. [aclr.com.es]

The presence of a brain stem abscess should especially alert the clinician to the Listeria as the possible etiology of the infection. [ahcmedia.com]

The epidemiologic implication of this observation is discussed. [ncbi.nlm.nih.gov]

Meningitis in Systemic Lupus Erythematosus Patients: Epidemiologic Profile of Listeria Monocytogenes Infection. a Single-Center Study [abstract]. [acrabstracts.org]

Contrary to the conventional epidemiology these patients were adults who were not immuno-compromised. Although all four cases produced positive cerebrospinal fluid cultures, in three, listeria was not microscopically identified. [pmj.bmj.com]

It would be the first illness and death tied to a recent Listeria recall if epidemiological tests establish a link. Shortly after she was born, little Kennedy Grace Briggs had difficulty breathing and developed a rash. [foodpoisoningbulletin.com]

The first classifies the wide variety of disorders that can cause neurologic symptoms the patient with cancer, discusses the pathophysiology of nervous system metastases, the pathophysiology and treatment of brain edema and the approach to supportive [books.google.ro]

[…] transplacental transmission during pregnancy ; or direct contact with infected vaginal secretions during birth Incubation time: 3–70 days (usually within a month) Risk factors Immunodeficiency Age > 60 Pregnancy Neonates References: [1] [2] [3] [4] Pathophysiology [amboss.com]

Authors’ Affiliations (1) Pediatric Highly Intensive Care Unit, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy References Villa G, Diana MC, [ijponline.biomedcentral.com]

Pathophysiology L monocytogenes is a motile, non–spore-forming, gram-positive bacillus that has aerobic and facultatively anaerobic characteristics. [emedicine.medscape.com]

Because the majority of listeria infections occur in patients who are immunosuppressed, it would be reasonable to provide education for healthcare professionals on preventing these infections in all patients receiving immunosuppressants, including anti-TNF-alpha [ncbi.nlm.nih.gov]

Blue Bell recalled all of its products last month after the Centers for Disease Control and Prevention found listeria bacteria in several frozen treat items produced in Blue Bell’s plants. [consumerist.com]

Some types of bacterial meningitis can be prevented through immunizations. There are vaccines that protect against pneumococcus, meningococcus, and Hib, all of which cause meningitis. Vaccinations are key to the prevention of meningitis. [healthline.com]

Prevention The best way to prevent a Listeria infection is by using careful food preparation techniques. Here are tips for avoiding the bacteria: All meat should be properly cooked. Refrigerate or freeze cooked foods within two hours of preparation. [livescience.com]

Prevention The most effective way to protect you and your child against certain types of bacterial meningitis is to get vaccinated. [cdc.gov]