Edit concept Question Editor Create issue ticket

Liver Dysfunction

Dysfunctions Liver


Presentation

  • RESULTS: A total of 36 patients were included (44.7 14.3 years, 22.2% male, and 19.2% of patients presented with liver failure).[ncbi.nlm.nih.gov]
Jaundice
  • Jaundice in hyperemesis gravidarum may cause physicians to suspect several underlying diseases. Jaundice appeared in a woman with hyperemesis gravidarum and an ultrasound revealed biliary sludge.[ncbi.nlm.nih.gov]
  • Keywords: liver failure, jaundice, metastases, chemotherapy, cisplatin This work is published and licensed by Dove Medical Press Limited.[dovepress.com]
  • This is called jaundice, or icterus. Normal bilirubin levels are 0.2 to 1.2 mg/dL of blood. You may notice jaundice when the bilirubin level reaches 3.0 mg/dL.[chemocare.com]
Scleral Icterus
  • icterus Vascular spiders (spider telangiectasias, spider angiomata) Splenomegaly Testicular atrophy Most patients with cirrhosis severe enough to lead to ascites have additional stigmata of cirrhosis on physical examination.[aafp.org]
  • Jaundice (yellowing of the skin) and scleral icterus (yellowing of the eyes) are often present, but may not be initially noted by patients or their families until relatively late in the course of the illness.[surgery.ucsf.edu]
Retinal Hemorrhage
  • Retinal hemorrhage should be considered as the differential diagnosis of myodesopsia in the patient treated by regorafenib.[ncbi.nlm.nih.gov]
Focal Seizure
  • On hospital day two, the patient developed new-onset focal seizures secondary to metabolic abnormalities that resulted in the initiation of levetiracetam 1000 mg intravenously twice daily.[ncbi.nlm.nih.gov]

Workup

  • The most important step in the assessment of patients with acute liver failure is to identify the cause, as certain causes demand immediate and specific treatment (see Workup ).[emedicine.medscape.com]
  • The underlying disorder can have a significant effect on morbidity and mortality in both mother and fetus, and a diagnostic workup should be initiated promptly.[clevelandclinicmeded.com]

Treatment

  • Few studies have evaluated the predictive criteria as a response to treatment.[ncbi.nlm.nih.gov]

Prognosis

  • However, the impact of MELD-XI on the prognosis of HF patients in general remains unclear. METHODS AND RESULTS: We retrospectively analyzed 562 patients who were admitted to our hospital for the treatment of decompensated HF.[ncbi.nlm.nih.gov]

Etiology

  • The etiology of acute liver dysfunction was unknown, however, we believe that the combination of oral glucocorticoid and lispro insulin was suitable and useful for preventing recurrent liver dysfunction in this patient.[ncbi.nlm.nih.gov]
  • Evaluation of the acute liver failure did not reveal an etiology, and he was transferred to a tertiary care hospital for further evaluation and care.[thoracic.org]
  • Physical examination of patients with cirrhosis may reveal a variety of findings that necessitate a hepatic- or gastrointestinal-based work-up to determine the etiology.[aafp.org]

Epidemiology

  • , 510515, China. 6 Vascular Biology Research Institute, Basic Course of School, Guangdong Pharmaceutical University, Guangzhou, 510006, China. 7 Department of Pathology, Shenzhen People's Hospital, Shenzhen, Guangdong, 515020, China. 8 Department of Epidemiology[ncbi.nlm.nih.gov]
  • He has since completed further training in emergency medicine, clinical toxicology, clinical epidemiology and health professional education.[lifeinthefastlane.com]
  • Hepatitis B and C virus infection and hepatocellular carcinoma in China: a review of epidemiology and control measures. Journal of epidemiology / Japan Epidemiological Association. 2011;21(6):401–16. pmid:22041528; PubMed Central PMCID: PMC3899457.[journals.plos.org]
  • Worldwide racial and ethnic distribution of α1-antitrypsin deficiency: summary of an analysis of published genetic epidemiologic surveys. Chest 2002 ; 122 : 1818 -1829.[clinchem.aaccjnls.org]
  • This new agent is parenterally transmitted, 7-9 its prevalence is from 1% to 2% in voluntary donors from the United States, and it is more frequent than HCV in the general population. 10 Although there has been rapid increase in the molecular and epidemiologic[bloodjournal.org]
Sex distribution
Age distribution

Pathophysiology

  • Furthermore, steatosis is also a common feature in both clinical pictures The pathogenesis of artificial nutrition associated with liver dysfunction is related to overfeeding and sepsis with a pathophysiology, similar to metabolic syndrome and type 2[journals.lww.com]
  • In: Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management. 10th ed. Philadelphia, Pa.: Saunders Elsevier; 2016. . Accessed Dec. 20, 2016. Milic S, et al.[mayoclinic.org]
  • Sleisenger & Fordtran's gastrointestinal and liver disease pathophysiology, diagnosis, management (PDF) (9th ed.). St. Louis, Mo.: MD Consult. ISBN 978-1-4160-6189-2 .[en.wikipedia.org]
  • Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology/Diagnosis/Management . 10th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 94. Wong MP, Moitra VK. Hepatic encephalopathy. In: Fleisher LA, Roizen MF, Roizen JD, eds.[medlineplus.gov]
  • Although numerous pathophysiologic mechanisms of injury exist, the final common pathway is persistent wound healing resulting in hepatic parenchymal fibrosis.[aafp.org]

Prevention

  • The etiology of acute liver dysfunction was unknown, however, we believe that the combination of oral glucocorticoid and lispro insulin was suitable and useful for preventing recurrent liver dysfunction in this patient.[ncbi.nlm.nih.gov]

Ask Question

5000 Characters left Format the text using: # Heading, **bold**, _italic_. HTML code is not allowed.
By publishing this question you agree to the TOS and Privacy policy.
• Use a precise title for your question.
• Ask a specific question and provide age, sex, symptoms, type and duration of treatment.
• Respect your own and other people's privacy, never post full names or contact information.
• Inappropriate questions will be deleted.
• In urgent cases contact a physician, visit a hospital or call an emergency service!