Presentation
Function of Nitrogen bubble in LA cartridge Why is Nitrogen Bubble present in the cartridge: 1-2mm in diameter and is present to prevent Oxygen from being trapped in the cartridge and potentially destroying the Vasopressor or vasoconstrictor, so this [juniordentist.com]
This case report presents a patient with right lateral rectus muscle palsy and blurred vision after bimaxillary anesthesia. Signs, symptoms, and pathophysiologic hypotheses of these complications are presented. [ncbi.nlm.nih.gov]
Entire Body System
- Surgical Procedure
BACKGROUND/OBJECTIVES: A few studies have documented the effect of local anesthesia for minor dermatologic surgical procedures on children and their parents. [ncbi.nlm.nih.gov]
The drug blocks nerves and in turn, numbs pain, during surgical procedures. Allergic reactions to the drug are rare, but excessive doses of the anesthesia can cause unconsciousness, seizures, low blood pressure and even cardiac arrest. [abcnews.go.com]
- Fever
A 55-year-old man was admitted to the Department of Internal Medicine of our hospital with chief complaints of fever, cough, and right-sided chest pain. [ncbi.nlm.nih.gov]
[…] management of pain.DB00297BupivacaineA local anesthetic used in a wide variety of superficial and invasive procedures.DB00645DyclonineAn topical anesthetic used prior to examination to suppress the gag reflex or for pain relief from canker sores and fever [drugbank.ca]
Also called a fever blister. Epidural space — The space surrounding the spinal fluid sac. [medical-dictionary.thefreedictionary.com]
Diseases, symptoms or conditions for which acupuncture has been proved-through controlled trials-to be an effective treatment: Adverse reactions to radiotherapy and/or chemotherapy Allergic rhinitis (including hay fever) Biliary colic Depression (including [puheenvuoro.uusisuomi.fi]
Malignant hyperthermia is a serious reaction that involves a fast or irregular heartbeat, high fever, breathing problems, and muscle spasms. [surgeryencyclopedia.com]
- Inguinal Hernia
METHODS: A prospective study included patients operated on inguinal hernia repair according to Lichtenstein technique from January 2013 to September 2014. [ncbi.nlm.nih.gov]
Thus, 90 patients diagnosed as incarcerated inguinal hernia and underwent emergency inguinal hernia repair were included in the final analysis. [bmcanesthesiol.biomedcentral.com]
Amid PK, Shulman AG, Lichtenstein IL (1996) Simultaneous repair of bilateral inguinal hernias under local anesthesia. Ann Surg 223: 249-252. Elton C, Stoodley BJ (2001) Repair of concomitant inguinal and femoral hernias under local anaesthesia. [omicsonline.org]
Podiatry operations, such as bunionectomy and hammertoe repair Cataract removal Cystoscopy (examination of the bladder using a flexible tube inserted through the urethra) Inguinal hernia repair, although some hernias are too complex to be repaired using [jamanetwork.com]
Respiratoric
- Sneezing
[…] anesthesia.DB00907CocaineAn ester local anesthetic used during diagnostic procedures and surgeries in or through the nasal cavities.DB01075DiphenhydramineA H1 receptor antihistamine used in the treatment of seasonal allergies, and various allergic reactions including sneezing [drugbank.ca]
It is speculated that propofol may suppress sneeze inhibitory neurons. Administration of an opioid prior to propofol and the local anesthetic injection may decrease the sternutatory reflex. [ncbi.nlm.nih.gov]
These reactions are characterized by signs such as urticaria, pruritus, erythema, angioneurotic edema (including laryngeal edema), tachycardia, sneezing, nausea, vomiting, dizziness, syncope, excessive sweating, elevated temperature, and possibly, anaphylactoid-like [globalrph.com]
- Rhinorrhea
The patient may develop hypotension, tachycardia, hives, angioedema, dyspnea, bronchospasm with wheezing, or rhinorrhea. Ceasing the operation immediately at the onset of any signs or symptoms of a severe allergic reaction is important. [emedicine.medscape.com]
Gastrointestinal
- Nausea
Patients given monitored anesthesia rather than general anesthesia experience fewer incidences of nausea and vomiting and typically can be discharged home safely and quickly. The image below depicts intraoral approach for an infraorbital block. [emedicine.medscape.com]
Complaints of postoperative nausea, vomiting, throat discomfort, and voice changes were significantly fewer in the LA-MAC group than in the GA group. [ncbi.nlm.nih.gov]
- Vomiting
Patients given monitored anesthesia rather than general anesthesia experience fewer incidences of nausea and vomiting and typically can be discharged home safely and quickly. The image below depicts intraoral approach for an infraorbital block. [emedicine.medscape.com]
Complaints of postoperative nausea, vomiting, throat discomfort, and voice changes were significantly fewer in the LA-MAC group than in the GA group. [ncbi.nlm.nih.gov]
- Gagging
[…] local or regional anesthesia for surgery and short-term management of pain.DB00297BupivacaineA local anesthetic used in a wide variety of superficial and invasive procedures.DB00645DyclonineAn topical anesthetic used prior to examination to suppress the gag [drugbank.ca]
If the throat was anesthetized, the patient cannot drink until the gag reflex returns. If a major extremity was anesthetized, the patient may have to wait until function returns before being discharged. [surgeryencyclopedia.com]
Tetracaine is also used for endoscopic procedures and gag control [1, 2]. Topical anesthesia will not cause a completely painless injection and that depends more on the needle gauge and duration of the injection. [intechopen.com]
Cardiovascular
- Hypertension
A 67-year-old man with systemic hypertension complained of visual disturbance after a dental local injection for circumzygomatic and circum-mandibular wire removal. Forty-nine days later, he had partly recovered his vision. [ncbi.nlm.nih.gov]
Epinephrine is contraindicated in patients with pheochromocytoma, hyperthyroidism, severe hypertension, or severe peripheral vascular occlusive disease. [emedicine.medscape.com]
But they differ from cocaine in that they can't be abused for the same effects and they don't produce hypertension or vasoconstriction. These drugs act on the pain receptors, the nociceptors, decreasing the rates at which they can fire. [verywellhealth.com]
They differ from cocaine mainly in that they have no abuse potential and do not act on the sympathoadrenergic system, i.e. they do not produce hypertension or local vasoconstriction, with the exception of Ropivacaine and Mepivacaine that do produce weak [en.wikipedia.org]
Jaw & Teeth
- Aphthous Stomatitis
Intraoral lesion occurrences after injection: Recurrent aphthous stomatitis and herpetic lesions originate from this type of lesion that can occur two days after the injection due to the trauma of the needle at the injection site. [intechopen.com]
Skin
- Urticaria
[…] surgeries in or through the nasal cavities.DB01075DiphenhydramineA H1 receptor antihistamine used in the treatment of seasonal allergies, and various allergic reactions including sneezing, runny nose, itchy/watery eyes, itching of nose or throat, pruritus, urticaria [drugbank.ca]
If urticaria is observed at the site of the test injection, the use of hyaluronidase is contraindicated. [emedicine.medscape.com]
Hypersensitivity to a local anaesthetic injected into the mucosal surfaces of the mouth can present with diffuse swelling of the face, which can appear like urticaria. [dermnetnz.org]
A physician should be notified immediately if any of the following occur: symptoms of an allergic reaction such as hives (urticaria), which are itchy swellings on the skin, or swelling in the mouth or throat severe headache blurred or double vision or [surgeryencyclopedia.com]
- Ulcer
The first being the ulceration due to lip biting and the scratch injury on the chin after inferior alveolar nerve block. The second report presents an unusual scratch injury on the ala of nose following maxillary infiltration anesthesia. [ncbi.nlm.nih.gov]
AnnotatedDB13683QuinisocaineNot AnnotatedDB06774CapsaicinA topical analgesic agent used for the symptomatic relief of neuropathic pain associated with post-herpetic neuralgia, as well as other muscle and joint pain.DB12532OxetacaineAn antacid used to treat gastritis, peptic ulcer [drugbank.ca]
[…] reactions to radiotherapy and/or chemotherapy Allergic rhinitis (including hay fever) Biliary colic Depression (including depressive neurosis and depression following stroke) Dysentery, acute bacillary Dysmenorrhoea, primary Epigastralgia, acute (in peptic ulcer [puheenvuoro.uusisuomi.fi]
Treating pain Slightly painful conditions, such as mouth ulcers and sore throats, can sometimes be treated with over-the-counter gels and sprays that contain a local anaesthetic. [nhs.uk]
- Pruritus
A case is presented that dramatizes the difficulties in determining the specific allergen after a patient undergoing several episodes of restorative dentistry with several varying regimens of local anesthesia repeatedly reacted with skin rashes and pruritus [ncbi.nlm.nih.gov]
[…] and surgeries in or through the nasal cavities.DB01075DiphenhydramineA H1 receptor antihistamine used in the treatment of seasonal allergies, and various allergic reactions including sneezing, runny nose, itchy/watery eyes, itching of nose or throat, pruritus [drugbank.ca]
Clinical signs of type I reactions include pruritus, urticaria, facial swelling, wheezing, dyspnea, cyanosis, laryngeal edema, nausea, vomiting, and abdominal cramping. [emedicine.medscape.com]
[…] heroin dependence Osteoarthritis Pain due to endoscopic examination Pain in thromboangiitis obliterans Polycystic ovary syndrome (Stein-Leventhal syndrome) Postextubation in children Postoperative convalescence Premenstrual syndrome Prostatitis, chronic Pruritus [puheenvuoro.uusisuomi.fi]
Preservative-free clonidine, administered into the epidural or subarachnoid space (150-450 µg), produces dose-dependent analgesia and, unlike opioids, does not produce depression of ventilation, pruritus, nausea, or vomiting. [nysora.com]
- Insect Bite
bites or minor skin irritations.DB01161ChloroprocaineA local anesthetic agent indicated for intrathecal injection in adults for the production of subarachnoid block, or spinal anesthesia.DB08987EtidocaineEtidocaine is marketed under the name Duranest [drugbank.ca]
Topical anesthetics are used to relieve pain and itching caused by conditions such as sunburn or other minor burns, insect bites or stings, poison ivy, poison oak, poison sumac, and minor cuts and scratches. [mayoclinic.org]
Over-the-counter local anesthetics are also available to provide temporary relief from pain, irritation, and itching caused by various conditions such as cold sores, canker sores, sore throats, sunburn, insect bites, poison ivy, and minor cuts and scratches [henryschein.com]
They are ingredients in a variety of nonprescription products that are applied to the skin to relieve the discomfort of sunburn, insect bites or stings, poison ivy, and minor cuts, scratches, and burns. [surgeryencyclopedia.com]
- Eczema
Allergic sensitization and possible cross-reaction to topical anesthetics are a potential occupational hazard for ophthalmologists, especially in providers with chronic eczema.14 Second, patients’ comorbidities must be considered prior to local anesthetic [ncbi.nlm.nih.gov]
Neurologic
- Seizure
Abstract We report a young male patient who experienced seizure after local injection of 3 mL 2% lidocaine with epinephrine 1:200,000 around a recurrent nasal angiofibroma. [ncbi.nlm.nih.gov]
CNS Depression – Conscious patients receiving CNS depressant drugs such as benzodiazepines or IV anesthetic drugs will have higher seizure threshold, and may not manifest seizure activity before complete CNS depression results. [openanesthesia.org]
Allergic reactions to the drug are rare, but excessive doses of the anesthesia can cause unconsciousness, seizures, low blood pressure and even cardiac arrest. [abcnews.go.com]
Overdose or inadvertent injection of an LA into a blood vessel can cause systemic toxicity, which mainly affects the CNS (tinnitus, seizures, etc.) and the CVS (bradycardia, arrhythmias, etc.). [amboss.com]
[…] med lokalanalgesi ved circumcision Research output: Contribution to journal › Journal article › Research › peer-review Overview Citationformats We present two cases in which two boys of four weeks and four and a half months, respectively, experienced seizures [research.regionh.dk]
- Headache
There is also a small risk of developing a severe headache called a spinal headache following a spinal or epidural block. [surgeryencyclopedia.com]
Temporary adverse effects that affect some people include: blurred vision, dizziness, and vomiting headache muscle twitching continuing numbness, weakness, or tingling Some people may have an allergic reaction. [medicalnewstoday.com]
There is a small risk of developing a severe headache called a spinal headache following a spinal or epidural block. This headache is severe when the patient is upright and hardly felt when the patient lies down. [medical-dictionary.thefreedictionary.com]
Headache, nausea, and drowsiness are also common. The goals of postoperative pain management are to minimize discomfort and allow you to move with less pain in order to participate in physical therapy after surgery. [orthoinfo.aaos.org]
- Convulsions
After the application of lidocaine, the infant stopped crying, and then generalized tonic-clonic convulsions and a diffuse erythematous rash developed. [ncbi.nlm.nih.gov]
Cardiotoxicity of local anesthetics can be compared using the CC/CNS dose ratio that is the ratio of the dose causing cardiac collapse (CC) to the dose causing seizure/convulsions. The lower the number the more cardiotoxic the drug (ex. [openanesthesia.org]
In low doses local anesthetic is an anti-convulsant C. The patient should be pre-medicated prior to treatment D. Epilepsy is an absolute contraindication to amide type anesthetics E. Oxygen should be available to deliver in an emergency [proprofs.com]
If no adrenaline is added then bradycardia with hypotension will occur. Severe toxicity: Usually about 4 - 7 times the convulsant dose needs to be injected before cardiovascular collapse occurs. [slideshare.net]
- Tremor
Other effects: the systemic diffusion of a local anesthetic can induce, in addition to vasodilation: cardiac effects: decrease of conduction and force of contraction, resulting in hypotension, even shock. neurological effects: tremors even seizures explained [pharmacorama.com]
As serum levels increase to 5-8 mcg/mL, nystagmus, slurred speech, localized muscle twitching, or fine tremors may be noticed. Patients also have been noted to have hallucinations at these levels. [emedicine.medscape.com]
CLINICAL MANIFESTATION OF LOCAL ANESTHETIC OVERDOSE SIGNS LOW TO MODERATE OVERDOSE LEVELS: • Confusion • Talkativeness • Apprehension • Excitedness • Slurred speech • Generalized stutter • Muscular twitching, tremor of face and extremities • Elevated [slideshare.net]
Self-limited side effects include palpitations, anxiety, sweating, tremor, tachycardia, and elevated blood pressure. [intechopen.com]
- Slurred Speech
The early signs/symptoms advance to CNS depression with slurred speech, drowsiness, unconsciousness, and then respiratory arrest. [openanesthesia.org]
speech 7 Muscular twitching (especially facial) 8 Irrational conversation ... 6 Fundamentals of Anaesthesia The gold standard text for the Primary FRCA exam - well established and covers full curriculum. [educalingo.com]
As serum levels increase to 5-8 mcg/mL, nystagmus, slurred speech, localized muscle twitching, or fine tremors may be noticed. Patients also have been noted to have hallucinations at these levels. [emedicine.medscape.com]
CLINICAL MANIFESTATION OF LOCAL ANESTHETIC OVERDOSE SIGNS LOW TO MODERATE OVERDOSE LEVELS: • Confusion • Talkativeness • Apprehension • Excitedness • Slurred speech • Generalized stutter • Muscular twitching, tremor of face and extremities • Elevated [slideshare.net]
Workup
The diagnostic workup for all patients before LC included a medical history, physical examination, and abdominal ultrasonography. [bmcsurg.biomedcentral.com]
Treatment
Local Anesthesia is a very integral part of almost every Dental Treatment performed which is used in making treatment procedures painless for the patient. [juniordentist.com]
The treatment outcome after SRP did not show a significant difference between gel and injection group (P > 0.05). [ncbi.nlm.nih.gov]
Prognosis
Conclusion Historically, elderly patients with ASDH treated with a traditional craniotomy performed under general anesthesia have not had a good prognosis. [ncbi.nlm.nih.gov]
This content is for informational purposes only and does not substitute for formal and individualized diagnosis, prognosis, treatment, prescription, and/or dietary advice from a licensed medical professional. [healdove.com]
Etiology
When postoperative altered sensation occurs, etiologic considerations should always include local anesthetic administration technique. [ncbi.nlm.nih.gov]
A possible etiology is retinal and choroid artery occlusion following the intra-arterial injection which strongly emphasizes the need for aspiration prior to the injection [42]. [intechopen.com]
Epidemiology
However, the latex stopper at the end of most cartridges has not been implicated in adverse reactions among dental patients, based on available case reports. 15 As with many dental issues, no prospective epidemiologic study has evaluated this issue. [dentistryiq.com]
Physicians at the Department of Epidemiology and the Department of Ophthalmology, Maastricht, the Netherlands, reviewed the literature in MEDLINE, EMBASE, CIN-AHL, PsychInfo, and Cochrane databases. [reviewofophthalmology.com]
Addiss DG, Shaffer N, Fowler BS, Tauxe RV (1990) The epidemiology of appendicitis and appendectomy in the United States. Am J Epidemiol 132: 910-925. [omicsonline.org]
Materials and methods Based on our preliminary observations that pain scores were decreased at least by half, the Department of Biostatistics and Epidemiology randomized 30 patients to receive either periprostatic lidocaine (group one) or no anesthetic [nature.com]
Statistical methods for assessing the influence of study characteristics on treatment effects in ‘meta-epidemiological’ research. Stat Med 2002 ; 21 : 1513 -24. ↵ Bradburn MJ, Deeks JJ, Berlin JA, Russell LA. [bmj.com]
Pathophysiology
Signs, symptoms, and pathophysiologic hypotheses of these complications are presented. [ncbi.nlm.nih.gov]
Prevention
This prevents elevated extracellular tissue pressure, a cause of ischemic damage to extraocular muscles or nerves. [ncbi.nlm.nih.gov]
Function of Nitrogen bubble in LA cartridge Why is Nitrogen Bubble present in the cartridge: 1-2mm in diameter and is present to prevent Oxygen from being trapped in the cartridge and potentially destroying the Vasopressor or vasoconstrictor, so this [juniordentist.com]
Local Anesthesia Part 1: Introduction & The Drugs CE Credit(s): 1 Member Price: $49.00 Retail Price: $69.00 Description: Updated for 2018 Local anesthetics, the most used drugs in dentistry, are the safest & most effective drugs for the prevention and [ebusiness.ada.org]
This prevents pain during surgical procedures. An anesthetic drug is applied to the part of the body that is to undergo surgery. It may be used with sedation, which calms the patient and reduces stress levels. [medicalnewstoday.com]