After ivermectin therapy, he re-presented with respiratory symptoms, peripheral eosinophilia and transient pulmonary infiltrates; the classic triad of Löffler's syndrome associated with invasive helminth infection. [ncbi.nlm.nih.gov]

The patient presents with a general slight fever and cough that last for less than 2 weeks. Treatment should aim to eradicate the parasite if it is present, or to stop the triggering drug. [gpnotebook.co.uk]

• Fever

  It is characterized by migratory pulmonary eosinophilic infiltrates and peripheral eosinophilia, with malaise, fever, and cough. [ncbi.nlm.nih.gov]

  Cause(s) : Parasites such as Strongyloides Stercoralis, Dirofilaria immitis Drug-Induced due to drugs like antimicrobials, anticonvulsants, anti-inflammatories, etc Symptoms : Symptoms related to: Parasitic infection Fever and body pain Cough, wheezing [medindia.net]

  Loeffler's syndrome A form of patchy pneumonia featuring fever, cough, difficulty in breathing, associated with a marked rise in the numbers of EOSINOPHIL white cells in the lungs and the circulating blood. [medical-dictionary.thefreedictionary.com]

  Another incident again involved a young boy who had suffered from vomiting and a fever for a span of 3 months. [en.wikipedia.org]

• Cough

  It is characterized by migratory pulmonary eosinophilic infiltrates and peripheral eosinophilia, with malaise, fever, and cough. [ncbi.nlm.nih.gov]

  Cause(s) : Parasites such as Strongyloides Stercoralis, Dirofilaria immitis Drug-Induced due to drugs like antimicrobials, anticonvulsants, anti-inflammatories, etc Symptoms : Symptoms related to: Parasitic infection Fever and body pain Cough, wheezing [medindia.net]

  Loeffler's syndrome A form of patchy pneumonia featuring fever, cough, difficulty in breathing, associated with a marked rise in the numbers of EOSINOPHIL white cells in the lungs and the circulating blood. [medical-dictionary.thefreedictionary.com]

  Differential diagnosis is carried out with hives, no observed pulmonary eosinophilic infiltrates and no symptomsof cough, shortness of breath, asthma attacks. [dixion-healthcare.com]

• Dyspnea

  He had not such symptoms as cough or dyspnea. In routine laboratory studies, eosinophilia was noted. Radiographic changes were transient and disappeared by day 25. Eosinophilia was also transient and gradually returned to normal level by 2 months. [ncbi.nlm.nih.gov]

  Cause(s) : Parasites such as Strongyloides Stercoralis, Dirofilaria immitis Drug-Induced due to drugs like antimicrobials, anticonvulsants, anti-inflammatories, etc Symptoms : Symptoms related to: Parasitic infection Fever and body pain Cough, wheezing, dyspnea [medindia.net]

  Fever, malaise, cough, wheezing, and dyspnea are the most common symptoms. Less commonly, the patient may present with myalgia, anorexia, and urticaria. [emedicine.medscape.com]

• Dry Cough

  cough, breathlessness Fever Diagnosis and Tests : Differential CBC count Stool examination Immunoglobin E level Analysis of sputum or gastric lavages Bronchoalveolar lavage Chest X-ray Chest CT scan Specialist to consult : Pulmonology [medindia.net]

  Clinical findings Chest pain, dry cough, fever, malaise, tachypnoea, dyspnoea, rash, wheezing. Imaging Diffuse infiltrates on plain AP film. Bronchoscopy Increased eosinophils. Management APE may respond to corticosteroids. [medical-dictionary.thefreedictionary.com]

  Symptoms General ill feeling ( malaise ) Fever Dry cough Chest pain Shortness of breath Wheezing Rapid respiratory rate Rash Note: Symptoms range from none at all to severe. They will usually go away without treatment. [medical-dictionary-search-engines.com]

  Dry cough, breathlessness, and fever are common. Obtain a detailed drug history. [patient.info]

  Dry cough, breathlessness, and fever are common. Obtain a detailed drug history, including prescription and over-the-counter medications, nutritional supplements, and illicit drugs. [emedicine.medscape.com]

• Pleural Effusion

  Pleural effusions and lymphadenopathy are not features. Treatment and prognosis The condition is usually self-limiting and treated conservatively. Opacities typically resolve within a month 3,5. [radiopaedia.org]

  In patients with nitrofurantoin toxicity there may even be pleural effusion. [patient.info]

  Eosinophilic pleural effusion associated with valproic acid administration. South Med J. 1995 Aug. 88(8):881-2. [Medline]. Kim Y, Lee KS, Choi DC, et al. The spectrum of eosinophilic lung disease: radiologic findings. [emedicine.medscape.com]

  Pleural effusions resolve more slowly than parenchymal opacities. Drug Name Select Trade methylprednisolone MEDROL prednisone RAYOS Click here for Patient Education NOTE: This is the Professional Version. [merckmanuals.com]

• Pulmonary Disorder

  Drug-induced pulmonary disorders. Intern Med. 2004 Mar. 43(3):169-70. [Medline]. Wang J, Palmer K, Lotvall J, et al. Circulating, but not local lung, IL-5 is required for the development of antigen-induced airways eosinophilia. [emedicine.medscape.com]

  Comprehensive collection of reviews covering a wide range of paediatric pulmonary disorders Each chapter presents a case scenario along with assessment and treatment of each disorder Key points summary at end of each chapter [books.google.com]

Subsequent to two syncopal episodes, a transthoracic echocardiogram was performed as part of the workup, which showed an unusual calcified mass in the left ventricular apical region but separate from the apical myocardium, with normal left ventricular [rwjms1.umdnj.edu]

• Pulmonary Infiltrate

  Abstract Eosinophilic pulmonary infiltration is an uncommon presentation from cocaine abuse. We present a patient with migratory pulmonary infiltrates and eosinophilia consistent with Löffler's syndrome. [ncbi.nlm.nih.gov]

  More and more attention has been given recently to pulmonary infiltrations with blood eosinophilia, climaxed by an editorial in FULL TEXT [annals.org]

• X-Ray Abnormal

  Description Löffler's disease, or simple pulmonary eosinophilia, was first described in 1932. [ 1 ] It is defined as transient respiratory illness associated with eosinophilia and chest X-ray abnormalities. [patient.info]

• Chest X-Ray Abnormal

  Description Löffler's disease, or simple pulmonary eosinophilia, was first described in 1932. [ 1 ] It is defined as transient respiratory illness associated with eosinophilia and chest X-ray abnormalities. [patient.info]

• Dirofilaria Immitis

  Cause(s) : Parasites such as Strongyloides Stercoralis, Dirofilaria immitis Drug-Induced due to drugs like antimicrobials, anticonvulsants, anti-inflammatories, etc Symptoms : Symptoms related to: Parasitic infection Fever and body pain Cough, wheezing [medindia.net]

  The parasite can be Strongyloides stercoralis, Dirofilaria immitis or Ascaris which can enter the body through contact with the soil. [en.wikipedia.org]

  immitis Clonorchis sinensis Paragonimus westermani Agents in drug-induced eosinophilia Antimicrobials - Dapsone, ethambutol, isoniazid, nitrofurantoin, penicillins, tetracyclines, clarithromycin, pyrimethamine, daptomycin [5] Anticonvulsants - Carbamazepines [emedicine.medscape.com]

• Toxocara Cati

  Recognised causes include: Infestations such as Ascaris lumbricoides (the most common parasite), Necator americanus, Strongyloides stercoralis, Ancylostoma duodenale, Toxocara canis and Toxocara cati, Entamoeba histolytica and Fasciola hepatica. [patient.info]

  Parasites Ascaris lumbricoides (the most common parasitic etiology) Ascaris suum Necator americanus Strongyloides stercoralis Ancylostoma braziliense Ancylostoma caninum Ancylostoma duodenale Toxocara canis Toxocara cati Entamoeba histolytica Fasciola [emedicine.medscape.com]

• Paragonimus Westermani

  westermani Agents in drug-induced eosinophilia Antimicrobials - Dapsone, ethambutol, isoniazid, nitrofurantoin, penicillins, tetracyclines, clarithromycin, pyrimethamine, daptomycin [5] Anticonvulsants - Carbamazepines, phenytoin, valproic acid, ethambutol [emedicine.medscape.com]

• Gnathostoma Spinigerum

  Gnathostoma spinigerum immunoblot was positive. [ncbi.nlm.nih.gov]

• Pleural Effusion

  Pleural effusions and lymphadenopathy are not features. Treatment and prognosis The condition is usually self-limiting and treated conservatively. Opacities typically resolve within a month 3,5. [radiopaedia.org]

  In patients with nitrofurantoin toxicity there may even be pleural effusion. [patient.info]

  Eosinophilic pleural effusion associated with valproic acid administration. South Med J. 1995 Aug. 88(8):881-2. [Medline]. Kim Y, Lee KS, Choi DC, et al. The spectrum of eosinophilic lung disease: radiologic findings. [emedicine.medscape.com]

  Pleural effusions resolve more slowly than parenchymal opacities. Drug Name Select Trade methylprednisolone MEDROL prednisone RAYOS Click here for Patient Education NOTE: This is the Professional Version. [merckmanuals.com]

Treatment If a cause is found, therapy consists of removing the offending drug or treating the infection with antibiotic or antiparasitic medication. Expectations (prognosis) The disease often resolves without treatment. [medical-dictionary-search-engines.com]

By the end of treatment, most of the cutaneous lesions, the pulmonary infiltrates and the peripheral eosinophilia had resolved. The final diagnosis was larva migrans associated with Löffler's syndrome. Copyright 2002 S. Karger AG, Basel [ncbi.nlm.nih.gov]

The disease is usually self-limited so it often resolves itself without treatment. Drugs Used to Treat Loeffler's Syndrome The following list of medications are in some way related to, or used in the treatment of this condition. [drugs.com]

Treatment should aim to eradicate the parasite if it is present, or to stop the triggering drug. Otherwise, there is no specific treatment as the disease is self-limiting. [gpnotebook.co.uk]

Complications Restrictive cardiomyopathy due to pericardial fibrosis Prognosis Often resolves without therapy; less commonly, it evolves to acute idiopathic eosinophilic pneumonia. [medical-dictionary.thefreedictionary.com]

Treatment and prognosis The condition is usually self-limiting and treated conservatively. Opacities typically resolve within a month 3,5. Complications A restrictive type cardiomyopathy can develop from endomyocardial fibrosis. [radiopaedia.org]

Treatment and Prognosis We value and respect our HERWriters' experiences, but everyone is different. Many of our writers are speaking from personal experience, and what's worked for them may not work for you. [empowher.com]

Expectations (prognosis) The disease often resolves without treatment. If treatment is needed, the response is usually good. However, relapses can occur. Complications A rare complication of simple pulmonary eosinophilia is severe pneumonia. [medical-dictionary-search-engines.com]

Prognosis Löffler's disease tends to follow an uncomplicated course and resolve completely within a month. Recurrence occurs only if infection recurs or the offending drug is reintroduced. [patient.info]

A1 - BAHK,Y W, PY - 1962/4/1/pubmed PY - 1962/4/1/medline PY - 1962/4/1/entrez KW - LOEFFLER'S SYNDROME/etiology KW - LUNG ABSCESS/parasitology KW - PARAGONIMUS/infection SP - 598 EP - 601 JF - Radiology JO - Radiology VL - 78 SN - 0033-8419 UR - 's_syndrome [wwww.unboundmedicine.com]

Etiology The cause is not usually identified but a number of allergens have been linked to the syndrome: parasites (e.g. [radiopaedia.org]

Parasites Ascaris lumbricoides (the most common parasitic etiology) Ascaris suum Necator americanus Strongyloides stercoralis Ancylostoma braziliense Ancylostoma caninum Ancylostoma duodenale Toxocara canis Toxocara cati Entamoeba histolytica Fasciola [emedicine.medscape.com]

Parasitic infections, especially ascariasis, may be the cause, but an identifiable etiologic agent is not found in up to one third of patients. [merckmanuals.com]

The original description of Löffler syndrome listed parasitic infection with Ascaris lumbricoides as its most common cause; however, other parasitic infections and acute hypersensitivity reactions to drugs are included as etiologies for simple pulmonary [emedicine.com]

The epidemiological aspect of Löffler's syndrome isn't well known since there have been minimal statistics reported on the topic. In 1909 a man named H. French first described the condition. [en.wikipedia.org]

Epidemiology This is an uncommon condition in the UK but is more likely in children and more likely in parts of the world where parasitic infestation abounds. [patient.info]

Epidemiology Frequency United States Intestinal helminthiases associated with Löffler syndrome, such as ascariasis, have a reported prevalence of 20-67% among children in rural southern communities. [emedicine.com]

Clinical manifestations, pathophysiology, and diagnosis of the hypereosinophilic syndromes. . Accessed July 22, 2016. . [mayoclinic.org]

Pathophysiology Löffler syndrome has classically been related to the transit of parasitic organisms through the lungs during their life cycle in the human host. [emedicine.com]

Celecoxib is a selective inhibitor of COX-2, and there is accumulating evidence that the induction and regulation of COX-2 may be key elements in the pathophysiological process of a number of inflammatory disorders and may play an important role in the [thorax.bmj.com]

Our patient was successfully treated with ivermectin, a corticosteroid cream, and inhalation medication in an early phase, which prevented complications. We present the details of this case and review the literature. [ncbi.nlm.nih.gov]

Prevention This is largely the prevention of parasitic infestation in endemic areas. Good hygiene and hand washing before eating are also important. Historical notes Wilhelm Löffler was born in 1887 and died in 1972. [patient.info]

Prevention This is a rare disorder. Many times, the cause cannot be found. Minimizing exposure to possible risk factors (certain medicines, some metals) may reduce risk. Update Date: 5/7/2003 David A. [medical-dictionary-search-engines.com]

Prevention of this syndrome is education-based, consisting of educating individuals on proper handwashing techniques, as well as how to correctly dispose of feces. [en.wikipedia.org]

The best way to prevent Strongyloides infection is to wear shoes when you are walking on soil, avoid contact with fecal matter or sewage, and clean up after dogs. Proper sewage disposal and fecal management are keys to prevention. [cdc.gov]